Casp14 (caspase 14) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Casp14 (caspase 14) Rattus norvegicus
Analyze
Symbol: Casp14
Name: caspase 14
RGD ID: 1311781
Description: Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in positive regulation of neuron apoptotic process. Located in keratin filament. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis. Orthologous to human CASP14 (caspase 14); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: caspase-14; LOC299587
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,577,315 - 11,583,987 (+)NCBIGRCr8
mRatBN7.2710,929,759 - 10,932,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,926,725 - 10,933,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,750,087 - 13,752,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,627,533 - 15,630,347 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,505,382 - 13,508,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,938,376 - 13,944,286 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,938,302 - 13,945,130 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,094,304 - 14,099,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,487,166 - 12,489,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,456,557 - 12,489,998 (+)NCBI
Celera79,047,174 - 9,050,006 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp14RatAutosomal Recessive Congenital Ichthyosis 12  ISOCASP14 (Homo sapiens)8554872ClinVar Annotator: match by term: Ichthyosis more ...ClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp14RatAutosomal Recessive Congenital Ichthyosis 12  ISOCASP14 (Homo sapiens)7240710 OMIM 

1 to 20 of 64 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp14Rat(+)-dexrazoxane multiple interactionsISOCasp14 (Mus musculus)6480464[Doxorubicin co-treated with Dexrazoxane] results in decreased expression of CASP14 mRNACTDPMID:26873546
Casp14Rat(S)-nicotine increases expressionISOCASP14 (Homo sapiens)6480464Nicotine results in increased expression of CASP14 mRNACTDPMID:23825647
Casp14Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expressionEXP 6480464o and p'-DDT analog results in decreased expression of CASP14 mRNACTDPMID:22937105
Casp14Rat1,2-dichloroethane increases expressionISOCasp14 (Mus musculus)6480464ethylene dichloride results in increased expression of CASP14 mRNACTDPMID:28960355
Casp14Rat1,2-dimethylhydrazine decreases expressionISOCasp14 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of CASP14 mRNACTDPMID:22206623
Casp14Rat17beta-estradiol increases expressionISOCASP14 (Homo sapiens)6480464Estradiol results in increased expression of CASP14 mRNACTDPMID:23373633
Casp14Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CASP14 mRNACTDPMID:19520675
Casp14Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCasp14 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CASP14 mRNACTDPMID:21570461
Casp14Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCasp14 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of CASP14 mRNACTDPMID:12167310 and PMID:17035482
Casp14Rat2,6-dimethoxyphenol multiple interactionsISOCASP14 (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in decreased expression of CASP14 proteinCTDPMID:38598786
Casp14Rat2-hydroxypropanoic acid decreases expressionISOCASP14 (Homo sapiens)6480464Lactic Acid results in decreased expression of CASP14 mRNACTDPMID:30851411
Casp14Rat4,4'-sulfonyldiphenol increases expressionISOCasp14 (Mus musculus)6480464bisphenol S results in increased expression of CASP14 mRNACTDPMID:38908815
Casp14Rat4,4'-sulfonyldiphenol increases expressionISOCASP14 (Homo sapiens)6480464bisphenol S results in increased expression of CASP14 mRNACTDPMID:33312107
Casp14Rataflatoxin B1 increases expressionISOCASP14 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of CASP14 mRNACTDPMID:32234424
Casp14Rataldrin increases expressionISOCasp14 (Mus musculus)6480464Aldrin results in increased expression of CASP14 mRNACTDPMID:18579281
Casp14Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of CASP14 mRNACTDPMID:35163327
Casp14Ratarsenite(3-) increases expressionISOCASP14 (Homo sapiens)6480464arsenite results in increased expression of CASP14 mRNACTDPMID:23974009
Casp14Ratbenzo[a]pyrene affects methylationISOCASP14 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of CASP14 promoterCTDPMID:27901495
Casp14Ratbeta-damascenone increases expressionISOCasp14 (Mus musculus)6480464beta-damascenone results in increased expression of CASP14 mRNACTDPMID:22982537
Casp14Ratbeta-damascenone affects localizationISOCasp14 (Mus musculus)6480464beta-damascenone affects the localization of CASP14 proteinCTDPMID:22982537

1 to 20 of 64 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp14Ratanimal organ development involved_inIEAARBA:ARBA000292471600115GO_REF:0000117UniProtGO_REF:0000117
Casp14Ratbiological_process  ND 159840709/2009: no relevant rat dataRGD 
Casp14Ratpositive regulation of apoptotic process involved_inIEAARBA:ARBA000277451600115GO_REF:0000117UniProtGO_REF:0000117
Casp14Ratpositive regulation of neuron apoptotic process involved_inIBAMGI:1277950 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Casp14Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Casp14Ratproteolysis involved_inIEAInterPro:IPR001309 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Casp14Ratsystem development involved_inIEAARBA:ARBA000277021600115GO_REF:0000117UniProtGO_REF:0000117

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp14Ratcornified envelope is_active_inIEAUniProtKB:O89094 and ensembl:ENSMUSP000000054881600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratcornified envelope is_active_inISOCasp14 (Mus musculus)1624291 PMID:26644517RGDPMID:26644517
Casp14Ratcytoplasm part_ofISOCASP14 (Homo sapiens)1624291 PMID:23377137RGDPMID:23377137
Casp14Ratcytoplasm part_ofIEAUniProtKB:P31944 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratcytoplasm is_active_inIBAFB:FBgn0010501 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Casp14Ratcytosol located_inISOCASP14 (Homo sapiens)1624291 RGDGO_REF:0000052
Casp14Ratcytosol located_inIEAUniProtKB:B2CIS9 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratcytosol located_inIEAUniProtKB:P31944 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratcytosol is_active_inIBAMGI:107700 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Casp14Ratkeratin filament  IDA 2313178 RGD 
Casp14Ratmitochondrion located_inIEAUniProtKB:B2CIS9 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratmitochondrion located_inISOCASP14 (Homo sapiens)1624291 RGDGO_REF:0000052
Casp14Ratmitochondrion located_inIEAUniProtKB:P31944 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratnucleoplasm located_inIEAUniProtKB:P31944 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratnucleoplasm located_inISOCASP14 (Homo sapiens)1624291 RGDGO_REF:0000052
Casp14Ratnucleoplasm located_inIEAUniProtKB:B2CIS9 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
Casp14Ratnucleus part_ofISOCASP14 (Homo sapiens)1624291 PMID:23377137RGDPMID:23377137
Casp14Ratnucleus part_ofIEAUniProtKB:P31944 and ensembl:ENSP000003934171600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 18 of 18 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp14Ratcysteine-type endopeptidase activity enablesIEAInterPro:IPR001309 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Casp14Ratcysteine-type peptidase activity enablesIEAInterPro:IPR0159171600115GO_REF:0000002InterProGO_REF:0000002
Casp14Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Casp14Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Casp14Ratprotein binding enablesISOCASP14 (Homo sapiens)1624291UniProtKB:P07602 more ...RGDPMID:24872419 and PMID:25416956


#
Reference Title
Reference Citation
1. Distribution of caspase-14 in epidermis and hair follicles is evolutionarily conserved among mammals. Alibardi L, etal., Anat Rec A Discov Mol Cell Evol Biol. 2005 Oct;286(2):962-73.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:23376485   PMID:23377137   PMID:23979707  



Casp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,577,315 - 11,583,987 (+)NCBIGRCr8
mRatBN7.2710,929,759 - 10,932,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,926,725 - 10,933,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,750,087 - 13,752,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,627,533 - 15,630,347 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,505,382 - 13,508,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,938,376 - 13,944,286 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,938,302 - 13,945,130 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,094,304 - 14,099,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,487,166 - 12,489,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,456,557 - 12,489,998 (+)NCBI
Celera79,047,174 - 9,050,006 (+)NCBICelera
Cytogenetic Map7q11NCBI
CASP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,049,480 - 15,058,293 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,049,480 - 15,058,293 (+)EnsemblGRCh38hg38GRCh38
GRCh371915,160,291 - 15,169,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,024,015 - 15,027,900 (+)NCBINCBI36Build 36hg18NCBI36
Build 341915,024,014 - 15,027,900NCBI
Celera1915,058,743 - 15,062,628 (+)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,727,867 - 14,736,682 (+)NCBIHuRef
CHM1_11915,159,760 - 15,168,573 (+)NCBICHM1_1
T2T-CHM13v2.01915,174,417 - 15,183,232 (+)NCBIT2T-CHM13v2.0
Casp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,547,829 - 78,554,181 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,547,825 - 78,554,128 (-)EnsemblGRCm39 Ensembl
GRCm381078,711,995 - 78,718,347 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,711,991 - 78,718,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,174,740 - 78,181,038 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,115,126 - 78,121,371 (-)NCBIMGSCv36mm8
Celera1079,733,914 - 79,740,355 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Casp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554958,213,763 - 8,221,616 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554958,214,512 - 8,221,124 (-)NCBIChiLan1.0ChiLan1.0
CASP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,938,212 - 19,970,641 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,955,262 - 18,987,678 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,594,810 - 14,604,109 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,565,543 - 15,574,402 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,565,543 - 15,574,402 (+)Ensemblpanpan1.1panPan2
CASP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,060,351 - 47,067,169 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,062,278 - 47,065,001 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,911,092 - 46,917,669 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,553,425 - 47,560,009 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,553,782 - 47,560,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,784,855 - 46,791,428 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02047,204,643 - 47,211,219 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,475,191 - 47,481,766 (-)NCBIUU_Cfam_GSD_1.0
Casp14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,846,067 - 205,852,182 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,396,866 - 5,399,278 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,396,866 - 5,399,255 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,524,183 - 62,531,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,522,294 - 62,531,594 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2262,076,316 - 62,089,874 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CASP14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,649,993 - 13,654,309 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,648,598 - 13,652,821 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,899,601 - 5,914,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,127,743 - 2,130,496 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,125,575 - 2,131,656 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Casp14
13 total Variants

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:85
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000009643
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat

1 to 10 of 16 rows



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 10 9 14 20 2 8 2 6 30 18 3 3 26 18



Ensembl Acc Id: ENSRNOT00000009643   ⟹   ENSRNOP00000009643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,926,725 - 10,933,405 (+)Ensembl
Rnor_6.0 Ensembl713,938,302 - 13,945,130 (+)Ensembl
RefSeq Acc Id: NM_001191776   ⟹   NP_001178705
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,580,339 - 11,583,171 (+)NCBI
mRatBN7.2710,929,759 - 10,932,591 (+)NCBI
Rnor_6.0713,940,638 - 13,943,470 (+)NCBI
Rnor_5.0714,094,304 - 14,099,953 (+)NCBI
Celera79,047,174 - 9,050,006 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263160   ⟹   XP_063119230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,577,315 - 11,583,987 (+)NCBI
Protein RefSeqs NP_001178705 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119230 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009643
  ENSRNOP00000009643.2
RefSeq Acc Id: NP_001178705   ⟸   NM_001191776
- UniProtKB: D3ZZ65 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009643   ⟸   ENSRNOT00000009643
RefSeq Acc Id: XP_063119230   ⟸   XM_063263160
- Peptide Label: isoform X1
- UniProtKB: D3ZZ65 (UniProtKB/TrEMBL)
Caspase family p10   Caspase family p20

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZ65-F1-model_v2 AlphaFold D3ZZ65 1-246 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695063
Promoter ID:EPDNEW_R5588
Type:multiple initiation site
Name:Casp14_1
Description:caspase 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0713,938,395 - 13,938,455EPDNEW


1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-34845 BioCyc
Ensembl Genes ENSRNOG00000007352 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009643 ENTREZGENE
  ENSRNOT00000009643.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1460 UniProtKB/TrEMBL
InterPro Caspase-like_dom UniProtKB/TrEMBL
  Caspase_cys_AS UniProtKB/TrEMBL
  Pept_C14 UniProtKB/TrEMBL
  Pept_C14_caspase UniProtKB/TrEMBL
  Pept_C14_ICE_p20 UniProtKB/TrEMBL
  Pept_C14_p10 UniProtKB/TrEMBL
  Pept_C14_p45_core UniProtKB/TrEMBL
KEGG Report rno:299587 UniProtKB/TrEMBL
NCBI Gene 299587 ENTREZGENE
PANTHER CASPASE UniProtKB/TrEMBL
  CASPASE-14 UniProtKB/TrEMBL
Pfam Peptidase_C14 UniProtKB/TrEMBL
PhenoGen Casp14 PhenoGen
PRINTS IL1BCENZYME UniProtKB/TrEMBL
PROSITE CASPASE_CYS UniProtKB/TrEMBL
  CASPASE_P10 UniProtKB/TrEMBL
  CASPASE_P20 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007352 RatGTEx
SMART CASc UniProtKB/TrEMBL
Superfamily-SCOP SSF52129 UniProtKB/TrEMBL
UniProt D3ZZ65 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Casp14  caspase 14   Casp14_predicted  caspase 14 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Casp14_predicted  caspase 14 (predicted)      Symbol and Name status set to approved 70820 APPROVED