Ch25h (cholesterol 25-hydroxylase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ch25h (cholesterol 25-hydroxylase) Rattus norvegicus
Analyze
Symbol: Ch25h
Name: cholesterol 25-hydroxylase
RGD ID: 1310575
Description: Predicted to enable C-4 methylsterol oxidase activity and cholesterol 25-hydroxylase activity. Predicted to be involved in several processes, including B cell chemotaxis; negative regulation of fusion of virus membrane with host plasma membrane; and sterol metabolic process. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human CH25H (cholesterol 25-hydroxylase); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrolein.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cholesterol 25-monooxygenase; LOC309527
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,428,048 - 241,429,366 (-)NCBIGRCr8
mRatBN7.21232,014,877 - 232,016,195 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,014,880 - 232,016,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,404,834 - 240,406,152 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01247,327,664 - 247,328,982 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,165,868 - 240,167,186 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01252,807,062 - 252,811,409 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,807,065 - 252,808,380 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01260,028,706 - 260,035,142 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41238,457,017 - 238,458,335 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11238,620,925 - 238,622,241 (-)NCBI
Celera1229,127,450 - 229,128,768 (-)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRatautoimmune lymphoproliferative syndrome  ISORGD:13215608554872ClinVar Annotator: match by term: AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE I, AUTOSOMAL DOMINANT | ClinVar Annotator: more ...ClinVarPMID:10875918|PMID:22237435|PMID:28492532
Ch25hRatFamilial Thoracic Aortic Aneurysm 6  ISORGD:13215608554872ClinVar Annotator: match by term: Aortic aneurysm, familial thoracic 6ClinVarPMID:28492532

1 to 20 of 98 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISORGD:132156064804642,2',4,4'-tetrabromodiphenyl ether affects the expression of CH25H mRNACTDPMID:31173147
Ch25hRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13215616480464Tetrachlorodibenzodioxin results in decreased expression of CH25H mRNACTDPMID:17035482|PMID:19933214
Ch25hRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CH25H mRNACTDPMID:33387578|PMID:34747641
Ch25hRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of CH25H mRNACTDPMID:22298810
Ch25hRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:13215616480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CH25H promoter]CTDPMID:19654925
Ch25hRat2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expressionISORGD:132156064804642,2',4,4',5-brominated diphenyl ether results in increased expression of CH25H mRNACTDPMID:26705709
Ch25hRat3,3',5,5'-tetrabromobisphenol A increases expressionISORGD:13215606480464tetrabromobisphenol A results in increased expression of CH25H mRNACTDPMID:33476716
Ch25hRat3,4-methylenedioxymethamphetamine decreases expressionISORGD:13215616480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of CH25H mRNACTDPMID:20188158
Ch25hRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORGD:13215606480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...CTDPMID:28628672
Ch25hRat4,4'-sulfonyldiphenol multiple interactionsISORGD:13215606480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ...CTDPMID:28628672
Ch25hRatacetamide increases expressionEXP 6480464acetamide results in increased expression of CH25H mRNACTDPMID:31881176
Ch25hRatacrolein increases expressionEXP 6480464Acrolein results in increased expression of CH25H mRNACTDPMID:38090360
Ch25hRatacrylamide decreases expressionISORGD:13215616480464Acrylamide results in decreased expression of CH25H mRNACTDPMID:35032568
Ch25hRataflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of CH25H mRNACTDPMID:25378103
Ch25hRatall-trans-retinoic acid multiple interactionsISORGD:13215616480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CH25H mRNACTDPMID:36189433
Ch25hRatarsenite(3-) multiple interactionsISORGD:13215606480464arsenite inhibits the reaction [G3BP1 protein binds to CH25H mRNA]CTDPMID:32406909
Ch25hRatbenzo[a]pyrene increases expressionISORGD:13215616480464Benzo(a)pyrene results in increased expression of CH25H mRNACTDPMID:22228805
Ch25hRatbenzo[a]pyrene decreases methylationISORGD:13215606480464Benzo(a)pyrene results in decreased methylation of CH25H exonCTDPMID:27901495
Ch25hRatbenzo[a]pyrene affects methylationISORGD:13215606480464Benzo(a)pyrene affects the methylation of CH25H promoterCTDPMID:27901495
Ch25hRatbeta-naphthoflavone multiple interactionsEXP 6480464[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CH25H mRNACTDPMID:18164116

1 to 20 of 98 rows

Biological Process
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRatB cell chemotaxis involved_inISSUniProtKB:Q9Z0F51600115GO_REF:0000024UniProtGO_REF:0000024
Ch25hRatB cell chemotaxis involved_inISORGD:13215611624291 PMID:22999953RGDPMID:22999953
Ch25hRatcholesterol metabolic process involved_inISORGD:13215601624291 PMID:33239446RGDPMID:33239446
Ch25hRatcholesterol metabolic process involved_inIBAMGI:1333869|PANTHER:PTN000221316|UniProtKB:O959921600115GO_REF:0000033GO_CentralGO_REF:0000033
Ch25hRatcholesterol metabolic process acts_upstream_of_or_withinISORGD:13215611624291 PMID:9852097RGDPMID:9852097
Ch25hRatcholesterol metabolic process involved_inISSUniProtKB:O959921600115GO_REF:0000024UniProtGO_REF:0000024
Ch25hRatlipid biosynthetic process involved_inIEAInterPro:IPR0066941600115GO_REF:0000002InterProGO_REF:0000002
Ch25hRatlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatnegative regulation of cholesterol metabolic process involved_inISORGD:13215611624291 PMID:29033131RGDPMID:29033131
Ch25hRatnegative regulation of fusion of virus membrane with host plasma membrane involved_inISSUniProtKB:O959921600115GO_REF:0000024UniProtGO_REF:0000024
Ch25hRatnegative regulation of fusion of virus membrane with host plasma membrane involved_inISORGD:13215601624291 PMID:32944968, PMID:33239446RGDPMID:32944968|PMID:33239446
Ch25hRatresponse to type I interferon involved_inISSUniProtKB:O959921600115GO_REF:0000024UniProtGO_REF:0000024
Ch25hRatresponse to type I interferon involved_inISORGD:13215601624291 PMID:33239446RGDPMID:33239446
Ch25hRatsteroid biosynthetic process involved_inIEAUniProtKB-KW:KW-07521600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatsteroid metabolic process involved_inIEAUniProtKB-KW:KW-07531600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatsterol biosynthetic process involved_inIBACGD:CAL0000198201|PANTHER:PTN000221246|SGD:S000003292|TAIR:locus:2043132|TAIR:locus:2118121|TAIR:locus:505006515|ZFIN:ZDB-GENE-040426-26701600115GO_REF:0000033GO_CentralGO_REF:0000033
Ch25hRatsterol biosynthetic process involved_inIEAUniProtKB-KW:KW-07561600115GO_REF:0000043UniProtGO_REF:0000043
1 to 17 of 17 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRatendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Ch25hRatendoplasmic reticulum membrane is_active_inIBAPANTHER:PTN000221246|SGD:S000003292|TAIR:locus:2024982|TAIR:locus:20431321600115GO_REF:0000033GO_CentralGO_REF:0000033
Ch25hRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRatC-4 methylsterol oxidase activity enablesIBACGD:CAL0000198201|PANTHER:PTN000221246|SGD:S000003292|TAIR:locus:2024982|TAIR:locus:2043132|TAIR:locus:2118121|TAIR:locus:5050065151600115GO_REF:0000033GO_CentralGO_REF:0000033
Ch25hRatcholesterol 25-hydroxylase activity enablesISSUniProtKB:Q9Z0F51600115GO_REF:0000024UniProtGO_REF:0000024
Ch25hRatcholesterol 25-hydroxylase activity enablesIEAEC:1.14.99.381600115GO_REF:0000003UniProtGO_REF:0000003
Ch25hRatcholesterol 25-hydroxylase activity enablesIEARHEA:211041600115GO_REF:0000116RHEAGO_REF:0000116
Ch25hRatcholesterol 25-hydroxylase activity enablesISORGD:13215611624291 PMID:22999953, PMID:29033131RGDPMID:22999953|PMID:29033131
Ch25hRatcholesterol 25-hydroxylase activity enablesISSUniProtKB:O959921600115GO_REF:0000024UniProtGO_REF:0000024
Ch25hRatcholesterol 25-hydroxylase activity enablesISORGD:13215601624291 PMID:32944968RGDPMID:32944968
Ch25hRatiron ion binding enablesIEAInterPro:IPR0066941600115GO_REF:0000002InterProGO_REF:0000002
Ch25hRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatmonooxygenase activity enablesIEAUniProtKB-KW:KW-05031600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatoxidoreductase activity enablesIEAUniProtKB-KW:KW-05601600115GO_REF:0000043UniProtGO_REF:0000043
Ch25hRatoxidoreductase activity enablesIEAInterPro:IPR0066941600115GO_REF:0000002InterProGO_REF:0000002
Ch25hRatprotein binding enablesISORGD:13215601624291UniProtKB:P32242|UniProtKB:P60329 PMID:32296183RGDPMID:32296183
Ch25hRatsteroid hydroxylase activity enablesIBAMGI:1333869|PANTHER:PTN000221316|UniProtKB:O959921600115GO_REF:0000033GO_CentralGO_REF:0000033
Ch25hRatsteroid hydroxylase activity enablesISORGD:13215611624291 PMID:9852097RGDPMID:9852097
1 to 15 of 15 rows

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRatbile acid biosynthetic pathway  ISORGD:132156010402751 SMPDBSMP:00035
Ch25hRatcerebrotendinous xanthomatosis pathway  ISORGD:132156010402751 SMPDBSMP:00315
Ch25hRatcongenital bile acid synthesis defect pathway  ISORGD:132156010402751 SMPDBSMP:00318
Ch25hRatcongenital bile acid synthesis defect pathway  ISORGD:132156010402751 SMPDBSMP:00314
Ch25hRatfamilial hypercholanemia pathway  ISORGD:132156010402751 SMPDBSMP:00317
Ch25hRatZellweger syndrome pathway  ISORGD:132156010402751 SMPDBSMP:00316

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ch25hRatbile acid biosynthetic pathway  IEA 6907045 KEGGrno:00120
Ch25hRatprimary bile acid biosynthetic pathway  IEA 6907045 KEGGrno:00120

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9852097   PMID:11207193   PMID:11967195   PMID:12390873   PMID:12477932   PMID:15489334   PMID:22999953   PMID:38331303  



Ch25h
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,428,048 - 241,429,366 (-)NCBIGRCr8
mRatBN7.21232,014,877 - 232,016,195 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,014,880 - 232,016,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,404,834 - 240,406,152 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01247,327,664 - 247,328,982 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,165,868 - 240,167,186 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01252,807,062 - 252,811,409 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,807,065 - 252,808,380 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01260,028,706 - 260,035,142 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41238,457,017 - 238,458,335 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11238,620,925 - 238,622,241 (-)NCBI
Celera1229,127,450 - 229,128,768 (-)NCBICelera
Cytogenetic Map1q53NCBI
CH25H
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381089,205,629 - 89,207,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1089,205,629 - 89,207,317 (-)EnsemblGRCh38hg38GRCh38
GRCh371090,965,386 - 90,967,074 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,955,674 - 90,957,051 (-)NCBINCBI36Build 36hg18NCBI36
Build 341090,955,673 - 90,957,051NCBI
Celera1084,712,523 - 84,713,900 (-)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1084,600,155 - 84,601,532 (-)NCBIHuRef
CHM1_11091,247,750 - 91,249,127 (-)NCBICHM1_1
T2T-CHM13v2.01090,089,526 - 90,091,214 (-)NCBIT2T-CHM13v2.0
Ch25h
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,451,183 - 34,452,548 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,451,178 - 34,452,564 (-)EnsemblGRCm39 Ensembl
GRCm381934,473,783 - 34,475,148 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,473,778 - 34,475,164 (-)EnsemblGRCm38mm10GRCm38
MGSCv371934,548,273 - 34,549,625 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361934,539,780 - 34,541,132 (-)NCBIMGSCv36mm8
Celera1935,249,457 - 35,250,809 (-)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.69NCBI
Ch25h
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554253,763,302 - 3,764,432 (+)NCBIChiLan1.0ChiLan1.0
CH25H
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28101,224,225 - 101,225,577 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110101,229,539 - 101,230,993 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01085,930,638 - 85,932,065 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11089,470,908 - 89,472,278 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1089,471,441 - 89,472,259 (-)Ensemblpanpan1.1panPan2
CH25H
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12638,884,356 - 38,885,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2638,635,628 - 38,637,001 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02640,468,717 - 40,470,089 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12638,339,014 - 38,340,386 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02637,902,557 - 37,903,928 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02639,172,313 - 39,173,684 (-)NCBIUU_Cfam_GSD_1.0
Ch25h
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721343,382,065 - 43,384,853 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366015,015,219 - 5,160,908 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366015,015,922 - 5,016,942 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CH25H
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14101,123,398 - 101,125,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114101,122,318 - 101,128,622 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214110,108,096 - 110,110,898 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CH25H
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1982,632,151 - 82,634,101 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl982,633,004 - 82,633,819 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604843,308,387 - 43,309,759 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ch25h
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473739,649 - 41,241 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Ch25h
7 total Variants

Predicted Target Of
Summary Value
Count of predictions:19
Count of miRNA genes:17
Interacting mature miRNAs:19
Transcripts:ENSRNOT00000025856
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 73 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464234238494Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat

1 to 10 of 73 rows
AI169398  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21232,015,144 - 232,015,348 (+)MAPPERmRatBN7.2
Rnor_6.01252,807,330 - 252,807,533NCBIRnor6.0
Rnor_5.01260,028,974 - 260,029,177UniSTSRnor5.0
RGSC_v3.41238,457,285 - 238,457,488UniSTSRGSC3.4
Celera1229,127,718 - 229,127,921UniSTS
RH 3.4 Map11591.0UniSTS
Cytogenetic Map1q52UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 56 31



Ensembl Acc Id: ENSRNOT00000025856   ⟹   ENSRNOP00000025856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1232,014,880 - 232,016,195 (-)Ensembl
Rnor_6.0 Ensembl1252,807,065 - 252,808,380 (-)Ensembl
RefSeq Acc Id: NM_001025415   ⟹   NP_001020586
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,428,048 - 241,429,366 (-)NCBI
mRatBN7.21232,014,877 - 232,016,195 (-)NCBI
Rnor_6.01252,807,062 - 252,808,380 (-)NCBI
Rnor_5.01260,028,706 - 260,035,142 (-)NCBI
RGSC_v3.41238,457,017 - 238,458,335 (-)RGD
Celera1229,127,450 - 229,128,768 (-)RGD
Sequence:
Protein RefSeqs NP_001020586 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH97964 (Get FASTA)   NCBI Sequence Viewer  
  CAR81281 (Get FASTA)   NCBI Sequence Viewer  
  CBX84759 (Get FASTA)   NCBI Sequence Viewer  
  EDM13160 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025856
  ENSRNOP00000025856.1
GenBank Protein Q4QQV7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020586   ⟸   NM_001025415
- UniProtKB: Q4QQV7 (UniProtKB/Swiss-Prot),   A6I129 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025856   ⟸   ENSRNOT00000025856
Fatty acid hydroxylase

Name Modeler Protein Id AA Range Protein Structure
AF-Q4QQV7-F1-model_v2 AlphaFold Q4QQV7 1-298 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690865
Promoter ID:EPDNEW_R1388
Type:single initiation site
Name:Ch25h_1
Description:cholesterol 25-hydroxylase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01252,808,396 - 252,808,456EPDNEW


1 to 16 of 16 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-55874 BioCyc
Ensembl Genes ENSRNOG00000019141 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025856 ENTREZGENE
  ENSRNOT00000025856.4 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7387594 IMAGE-MGC_LOAD
InterPro Fatty_acid_hydroxylase UniProtKB/Swiss-Prot
  Sterol_Desaturase_Related UniProtKB/Swiss-Prot
KEGG Report rno:309527 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116092 IMAGE-MGC_LOAD
NCBI Gene 309527 ENTREZGENE
PANTHER STEROL DESATURASE UniProtKB/Swiss-Prot
Pfam FA_hydroxylase UniProtKB/Swiss-Prot
PhenoGen Ch25h PhenoGen
RatGTEx ENSRNOG00000019141 RatGTEx
UniProt A6I129 ENTREZGENE, UniProtKB/TrEMBL
  CH25H_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 16 of 16 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ch25h  cholesterol 25-hydroxylase  Ch25h_predicted  cholesterol 25-hydroxylase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ch25h_predicted  cholesterol 25-hydroxylase (predicted)      Symbol and Name status set to approved 70820 APPROVED