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Gene: Tmem127 (transmembrane protein 127) Rattus norvegicus

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Symbol:

Tmem127

Name:

transmembrane protein 127

RGD ID:

1309744

Description:

Predicted to enable small GTPase binding activity. Predicted to be involved in negative regulation of TOR signaling and negative regulation of cell population proliferation. Predicted to act upstream of or within endosome organization. Predicted to be located in early endosome and plasma membrane. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in pheochromocytoma. Orthologous to human TMEM127 (transmembrane protein 127); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC311405; MGC156781; RGD1309744; similar to hypothetical protein FLJ20507

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM127 (transmembrane protein 127)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tmem127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem127 (transmembrane protein 127)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tmem127 (transmembrane protein 127)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Homo sapiens (human):	TMEM127 (transmembrane protein 127)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tmem127 (transmembrane protein 127)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tmem127	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	134,919,416 - 134,932,210 (+)	NCBI		GRCr8
mRatBN7.2	3	114,466,095 - 114,478,894 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	114,466,171 - 114,477,519 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	118,357,660 - 118,370,450 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	126,953,204 - 126,965,994 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	124,613,584 - 124,626,374 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	119,677,575 - 119,690,371 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	119,677,575 - 119,690,366 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	126,202,774 - 126,215,589 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	114,746,454 - 114,759,251 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	114,652,049 - 114,664,824 (+)	NCBI
Celera	3	113,306,634 - 113,319,570 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	acute myeloid leukemia		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Acute myeloid leukemia, adult	ClinVar	PMID:20923864\|PMID:25741868\|PMID:28492532
Tmem127	Rat	acute promyelocytic leukemia		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Acute promyelocytic leukemia	ClinVar	PMID:25741868\|PMID:28492532\|PMID:32575117
Tmem127	Rat	Hereditary Neoplastic Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23551308\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28646318\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	Hereditary Neoplastic Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23551308\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28646318\|PMID:28717660\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30246500\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:35189708\|PMID:36451132\|PMID:36655350\|PMID:9536098
Tmem127	Rat	Hereditary Neoplastic Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:16199547\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23551308\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28646318\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	Hereditary Neoplastic Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:16199547\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28492532\|PMID:28567294\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	Hereditary Neoplastic Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:16199547\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28492532\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338
Tmem127	Rat	Hereditary Neoplastic Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:16199547\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28492532\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:33051659
Tmem127	Rat	Hereditary Paraganglioma-Pheochromocytoma Syndromes		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paraganglioma-Pheochromocytoma Syndromes	ClinVar	PMID:16199547\|PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28646318\|PMID:28717660\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30246500\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:35189708\|PMID:36451132\|PMID:36655350\|PMID:9536098
Tmem127	Rat	intellectual disability		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar
Tmem127	Rat	Islet Cell Tumor Syndrome		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Chromaffinoma	ClinVar	PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28492532\|PMID:28717660\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30246500\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338\|PMID:35189708\|PMID:36451132\|PMID:36655350\|PMID:9536098
Tmem127	Rat	Multiple mitochondrial dysfunctions syndrome 10		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Multiple mitochondrial dysfunctions syndrome 10	ClinVar	PMID:25741868\|PMID:26267327\|PMID:26467025\|PMID:28492532\|PMID:33051659\|PMID:33219105
Tmem127	Rat	ocular melanoma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Intraocular melanoma	ClinVar	PMID:25741868\|PMID:28492532
Tmem127	Rat	ovarian cancer		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Ovarian cancer	ClinVar	PMID:25741868\|PMID:28492532
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:16199547\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28855235\|PMID:29282712\|PMID:29909963\|PMID:30877234\|PMID:31666924\|PMID:32877928\|PMID:33051659\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:16199547\|PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28646318\|PMID:28717660\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30246500\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:35189708\|PMID:36451132\|PMID:36655350\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:16199547\|PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28646318\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas	ClinVar	PMID:16199547\|PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas	ClinVar	PMID:16199547\|PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:33051659\|PMID:33219105\|PMID:34308366\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:16199547\|PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22517554\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28458909\|PMID:28492532\|PMID:28567294\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas	ClinVar	PMID:16199547\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28492532\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338\|PMID:9536098
Tmem127	Rat	paraganglioma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:16199547\|PMID:17576681\|PMID:20154675\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:25800244\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:28384794\|PMID:28492532\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:33051659\|PMID:33219105\|PMID:9536098
Tmem127	Rat	pheochromocytoma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Pheochromocytoma \| ClinVar Annotator: match by term: Pheochromocytoma, susceptibility to	ClinVar	PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:20301715\|PMID:20923864\|PMID:21156949\|PMID:21613359\|PMID:22136840\|PMID:22419703\|PMID:22541004\|PMID:23666964\|PMID:24033266\|PMID:24334765\|PMID:24694336\|PMID:25389632\|PMID:25637381\|PMID:25741868\|PMID:26267327\|PMID:26269449\|PMID:26467025\|PMID:26960314\|PMID:27153395\|PMID:28384794\|PMID:28492532\|PMID:28717660\|PMID:28855235\|PMID:29282712\|PMID:29625052\|PMID:29909963\|PMID:30113886\|PMID:30246500\|PMID:30877234\|PMID:31666924\|PMID:32575117\|PMID:32877928\|PMID:32994724\|PMID:33051659\|PMID:33219105\|PMID:34439168\|PMID:34870338\|PMID:35189708\|PMID:36451132\|PMID:36655350\|PMID:9536098
Tmem127	Rat	schizophrenia		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106\|PMID:30208311
Tmem127	Rat	Smith-Magenis syndrome		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Chromosome 17p11.2 deletion syndrome	ClinVar	PMID:16266984\|PMID:17576681\|PMID:20154675\|PMID:25389632\|PMID:25741868\|PMID:28492532\|PMID:9536098
Tmem127	Rat	uveal melanoma		ISO	RGD:1601991	8554872	ClinVar Annotator: match by term: Uveal melanoma	ClinVar	PMID:25741868\|PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	pheochromocytoma		ISO	RGD:1601991	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:20154675

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	pheochromocytoma	susceptibility	ISO	RGD:1601991	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	RGD:1331860	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TMEM127 mRNA	CTD	PMID:36331819
Tmem127	Rat	1,2-dimethylhydrazine	affects expression	ISO	RGD:1331860	6480464	1,2-Dimethylhydrazine affects the expression of TMEM127 mRNA	CTD	PMID:22206623
Tmem127	Rat	17alpha-ethynylestradiol	affects expression	ISO	RGD:1331860	6480464	Ethinyl Estradiol affects the expression of TMEM127 mRNA	CTD	PMID:17555576
Tmem127	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1331860	6480464	Tetrachlorodibenzodioxin affects the expression of TMEM127 mRNA	CTD	PMID:21570461
Tmem127	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of TMEM127 mRNA	CTD	PMID:33387578
Tmem127	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1331860	6480464	bisphenol S results in decreased expression of TMEM127 mRNA	CTD	PMID:39298647
Tmem127	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of TMEM127 mRNA	CTD	PMID:24780913
Tmem127	Rat	acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of TMEM127 mRNA	CTD	PMID:28959563
Tmem127	Rat	all-trans-retinoic acid	increases expression	ISO	RGD:1601991	6480464	Tretinoin results in increased expression of TMEM127 mRNA	CTD	PMID:33167477
Tmem127	Rat	antirheumatic drug	decreases expression	ISO	RGD:1601991	6480464	Antirheumatic Agents results in decreased expression of TMEM127 mRNA	CTD	PMID:24449571
Tmem127	Rat	benzene	increases expression	ISO	RGD:1601991	6480464	Benzene results in increased expression of TMEM127 mRNA	CTD	PMID:19162166
Tmem127	Rat	benzo[a]pyrene	decreases methylation	ISO	RGD:1601991	6480464	Benzo(a)pyrene results in decreased methylation of TMEM127 3' UTR	CTD	PMID:27901495
Tmem127	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1331860	6480464	Diethylhexyl Phthalate results in increased expression of TMEM127 mRNA	CTD	PMID:34319233
Tmem127	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of TMEM127 mRNA	CTD	PMID:25181051\|PMID:30816183
Tmem127	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of TMEM127 mRNA	CTD	PMID:34947998
Tmem127	Rat	bisphenol A	decreases expression	ISO	RGD:1331860	6480464	bisphenol A results in decreased expression of TMEM127 mRNA	CTD	PMID:33221593
Tmem127	Rat	carbamazepine	affects expression	ISO	RGD:1601991	6480464	Carbamazepine affects the expression of TMEM127 mRNA	CTD	PMID:25979313
Tmem127	Rat	CGP 52608	multiple interactions	ISO	RGD:1601991	6480464	CGP 52608 promotes the reaction [RORA protein binds to TMEM127 gene]	CTD	PMID:28238834
Tmem127	Rat	choline	multiple interactions	ISO	RGD:1331860	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ...	CTD	PMID:20938992
Tmem127	Rat	cisplatin	increases expression	ISO	RGD:1601991	6480464	Cisplatin results in increased expression of TMEM127 mRNA	CTD	PMID:27392435
Tmem127	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1601991	6480464	di-n-butylphosphoric acid affects the expression of TMEM127 mRNA	CTD	PMID:37042841
Tmem127	Rat	doxorubicin	decreases expression	ISO	RGD:1601991	6480464	Doxorubicin results in decreased expression of TMEM127 mRNA	CTD	PMID:29803840
Tmem127	Rat	ethanol	affects splicing	ISO	RGD:1331860	6480464	Ethanol affects the splicing of TMEM127 mRNA	CTD	PMID:30319688
Tmem127	Rat	fenthion	decreases expression	ISO	RGD:1331860	6480464	Fenthion results in decreased expression of TMEM127 mRNA	CTD	PMID:34813904
Tmem127	Rat	flutamide	decreases expression	EXP		6480464	Flutamide results in decreased expression of TMEM127 mRNA	CTD	PMID:24136188
Tmem127	Rat	folic acid	multiple interactions	ISO	RGD:1331860	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ...	CTD	PMID:20938992
Tmem127	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of TMEM127 mRNA	CTD	PMID:33387578
Tmem127	Rat	L-methionine	multiple interactions	ISO	RGD:1331860	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ...	CTD	PMID:20938992
Tmem127	Rat	paracetamol	affects expression	ISO	RGD:1331860	6480464	Acetaminophen affects the expression of TMEM127 mRNA	CTD	PMID:17562736
Tmem127	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	RGD:1331860	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TMEM127 mRNA	CTD	PMID:36331819
Tmem127	Rat	propiconazole	decreases expression	ISO	RGD:1331860	6480464	propiconazole results in decreased expression of TMEM127 mRNA	CTD	PMID:21278054
Tmem127	Rat	sodium arsenite	increases expression	ISO	RGD:1601991	6480464	sodium arsenite results in increased expression of TMEM127 mRNA	CTD	PMID:38568856
Tmem127	Rat	sulindac	increases expression	ISO	RGD:1601991	6480464	Sulindac results in increased expression of TMEM127 mRNA	CTD	PMID:11906190
Tmem127	Rat	thiram	decreases expression	ISO	RGD:1601991	6480464	Thiram results in decreased expression of TMEM127 mRNA	CTD	PMID:38568856
Tmem127	Rat	titanium dioxide	decreases methylation	ISO	RGD:1331860	6480464	titanium dioxide results in decreased methylation of TMEM127 gene	CTD	PMID:35295148
Tmem127	Rat	triphenyl phosphate	affects expression	ISO	RGD:1601991	6480464	triphenyl phosphate affects the expression of TMEM127 mRNA	CTD	PMID:37042841
Tmem127	Rat	urethane	increases expression	ISO	RGD:1601991	6480464	Urethane results in increased expression of TMEM127 mRNA	CTD	PMID:28818685
Tmem127	Rat	valproic acid	increases expression	ISO	RGD:1601991	6480464	Valproic Acid results in increased expression of TMEM127 mRNA	CTD	PMID:23179753

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	biological_process		ND		1598407	01/2009: no relevant rat data	RGD
Tmem127	Rat	endosome organization	acts_upstream_of_or_within	ISO	RGD:1331860	1624291	MGI:5581337 PMID:24334765	RGD	PMID:24334765
Tmem127	Rat	endosome organization	acts_upstream_of_or_within	IEA	UniProtKB:Q8BGP5\|ensembl:ENSMUSP00000035434	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem127	Rat	negative regulation of cell population proliferation	involved_in	ISO	RGD:1601991	1624291	PMID:20154675	RGD	PMID:20154675
Tmem127	Rat	negative regulation of cell population proliferation	involved_in	IEA	UniProtKB:O75204\|ensembl:ENSP00000258439	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem127	Rat	negative regulation of cell population proliferation	involved_in	IEA	InterPro:IPR033331	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Tmem127	Rat	negative regulation of TOR signaling	involved_in	ISO	RGD:1601991	1624291	PMID:20154675	RGD	PMID:20154675
Tmem127	Rat	negative regulation of TOR signaling	involved_in	IEA	UniProtKB:O75204\|ensembl:ENSP00000258439	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem127	Rat	negative regulation of TOR signaling	involved_in	IEA	InterPro:IPR033331	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Tmem127	Rat	regulation of TOR signaling	involved_in	IBA	MGI:1916720\|PANTHER:PTN002002006\|UniProtKB:O75204	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tmem127	Rat	regulation of TOR signaling	acts_upstream_of_or_within	IEA	UniProtKB:Q8BGP5\|ensembl:ENSMUSP00000035434	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem127	Rat	regulation of TOR signaling	acts_upstream_of_or_within	ISO	RGD:1331860	1624291	MGI:5581337 PMID:24334765	RGD	PMID:24334765

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	cytoplasm	located_in	ISO	RGD:1601991	1624291	PMID:20154675	RGD	PMID:20154675
Tmem127	Rat	cytoplasm	located_in	IEA	UniProtKB:O75204\|ensembl:ENSP00000258439	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem127	Rat	early endosome	located_in	ISO	RGD:1601991	1624291	PMID:24334765	RGD	PMID:24334765
Tmem127	Rat	early endosome	located_in	IEA	UniProtKB:O75204\|ensembl:ENSP00000258439	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Tmem127	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tmem127	Rat	membrane	is_active_in	IBA	PANTHER:PTN002002006\|UniProtKB:O75204	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tmem127	Rat	plasma membrane	located_in	ISO	RGD:1601991	1624291	PMID:20154675	RGD	PMID:20154675
Tmem127	Rat	plasma membrane	located_in	IEA	UniProtKB:O75204\|ensembl:ENSP00000258439	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem127	Rat	small GTPase binding	enables	ISO	RGD:1601991	1624291	PMID:24334765	RGD	PMID:24334765
Tmem127	Rat	small GTPase binding	enables	IEA	UniProtKB:O75204\|ensembl:ENSP00000258439	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

PMID:12477932	PMID:20154675	PMID:22871113	PMID:24334765

Tmem127
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	134,919,416 - 134,932,210 (+)	NCBI		GRCr8
mRatBN7.2	3	114,466,095 - 114,478,894 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	114,466,171 - 114,477,519 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	118,357,660 - 118,370,450 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	126,953,204 - 126,965,994 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	124,613,584 - 124,626,374 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	119,677,575 - 119,690,371 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	119,677,575 - 119,690,366 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	126,202,774 - 126,215,589 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	114,746,454 - 114,759,251 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	114,652,049 - 114,664,824 (+)	NCBI
Celera	3	113,306,634 - 113,319,570 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

TMEM127
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	96,248,514 - 96,265,997 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	96,248,500 - 96,266,047 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	96,914,252 - 96,931,735 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	96,280,039 - 96,295,459 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	91,357,500 - 91,372,939 (-)	NCBI		Celera
Cytogenetic Map	2	q11.2	NCBI
HuRef	2	90,877,443 - 90,893,248 (-)	NCBI		HuRef
CHM1_1	2	96,920,300 - 96,936,106 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	96,755,122 - 96,772,605 (-)	NCBI		T2T-CHM13v2.0

Tmem127
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	127,089,868 - 127,103,028 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	127,089,828 - 127,103,027 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	127,247,904 - 127,261,108 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	127,247,908 - 127,261,107 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	127,073,711 - 127,086,500 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	126,939,416 - 126,952,205 (+)	NCBI		MGSCv36	mm8
Celera	2	128,487,347 - 128,500,147 (+)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	61.87	NCBI

Tmem127
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	3,808,455 - 3,822,497 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955470	3,809,835 - 3,822,442 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM127
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	32,042,817 - 32,057,217 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	32,045,577 - 32,059,977 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	103,049,655 - 103,065,116 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	97,174,322 - 97,189,177 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	97,174,322 - 97,189,171 (-)	Ensembl	panpan1.1		panPan2

TMEM127
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	34,512,753 - 34,527,208 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	34,512,792 - 34,523,692 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	34,282,678 - 34,295,473 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	35,283,964 - 35,296,760 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	35,283,938 - 35,296,757 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	34,413,107 - 34,426,110 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	34,481,752 - 34,494,521 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	34,688,570 - 34,701,364 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem127
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	83,091,414 - 83,106,154 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936744	344,356 - 359,044 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936744	344,356 - 359,086 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM127
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	46,966,892 - 46,978,810 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	46,966,858 - 47,017,659 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	49,108,738 - 49,121,833 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM127
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	671,259 - 685,217 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	673,375 - 685,228 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	168,096,788 - 168,111,829 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem127
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	2,333,472 - 2,344,674 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624749	2,333,472 - 2,344,652 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Tmem127
62 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	402
Count of miRNA genes:	231
Interacting mature miRNAs:	276
Transcripts:	ENSRNOT00000031577
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	84091273	129091273	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	112287552	135181505	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat

RH131467

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	114,478,542 - 114,478,723 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	119,690,020 - 119,690,200	NCBI	Rnor6.0
Rnor_5.0	3	126,215,238 - 126,215,418	UniSTS	Rnor5.0
RGSC_v3.4	3	114,758,900 - 114,759,080	UniSTS	RGSC3.4
Celera	3	113,319,219 - 113,319,399	UniSTS
RH 3.4 Map	3	998.6	UniSTS
Cytogenetic Map	3	q36	UniSTS

RH134539

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	37,678,069 - 37,678,260 (+)	MAPPER	mRatBN7.2
mRatBN7.2	3	114,477,209 - 114,477,400 (-)	MAPPER	mRatBN7.2
mRatBN7.2	3	114,477,209 - 114,477,400 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	119,688,687 - 119,688,877	NCBI	Rnor6.0
Rnor_6.0	11	39,764,643 - 39,764,833	NCBI	Rnor6.0
Rnor_5.0	3	126,213,905 - 126,214,095	UniSTS	Rnor5.0
Rnor_5.0	11	42,970,012 - 42,970,202	UniSTS	Rnor5.0
RGSC_v3.4	3	114,757,567 - 114,757,757	UniSTS	RGSC3.4
RGSC_v3.4	11	38,545,442 - 38,545,632	UniSTS	RGSC3.4
Celera	11	37,556,695 - 37,556,885	UniSTS
Celera	3	113,317,886 - 113,318,076	UniSTS
Cytogenetic Map	3	q36	UniSTS

AI317350

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	114,478,364 - 114,478,451 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	119,689,842 - 119,689,928	NCBI	Rnor6.0
Rnor_5.0	3	126,215,060 - 126,215,146	UniSTS	Rnor5.0
RGSC_v3.4	3	114,758,722 - 114,758,808	UniSTS	RGSC3.4
Celera	3	113,319,041 - 113,319,127	UniSTS
Cytogenetic Map	3	q36	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001100978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC131850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000031577 ⟹ ENSRNOP00000030631

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	119,677,575 - 119,690,366 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117496 ⟹ ENSRNOP00000097003

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	114,466,171 - 114,477,519 (+)	Ensembl

RefSeq Acc Id:

NM_001100978 ⟹ NP_001094448

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,919,417 - 134,932,210 (+)	NCBI
mRatBN7.2	3	114,466,101 - 114,478,894 (+)	NCBI
Rnor_6.0	3	119,677,575 - 119,690,371 (+)	NCBI
Rnor_5.0	3	126,202,774 - 126,215,589 (+)	NCBI
RGSC_v3.4	3	114,746,454 - 114,759,251 (+)	RGD
Celera	3	113,306,634 - 113,319,570 (+)	RGD

Sequence:

show sequence

GAAGCCGGAAGTGCATCGGCCAGGGTCCGTCTGGGCGTTGCGGGATTGGGGCCTGGGATCTCTTGGCCCCGGCAGCTAAGAAGCCTGTGACCGGGCGAAGCGGCGCCATCCCAGCCCTGAGGCCTGCT
GACCGACAGGCTCTGCGTTCCCCGCTGAGGTCGGCGGCCACTACCAGCGACCGCAGAGCTACAGCGGGCAGCCCCGGGCATGTATGCCCCTGGAGGCGCCGGGCTGCCGGGAGGGCGCCGGCGGAGAA
GCCCGGGAAGCAGCGCTCTTCCTAAGCAGCCGGAGCGGAGCCTGGCTTCGGCCCTGCCTGGCGCCCTGTCCATCACAGCGCTGTGCACTGCCCTCGCGGAGCCCGCTTGGTTGCACATCCATGGAGGC
ACCTGTTCCCGCCAGGAGCTGGGGGTCTCAGACGTGCTGGGCTATGTGCACCCGGATCTGCTAAAAGATTTCTGCATGAACCCCCAAACAGTTCTTCTCCTGAGGGTCATCGCTGCCTTCTGCTTCTT
GGGCATCCTGTGTAGTCTCTCTGCATTCCTGTTGGATGTCTTTGGGCCCAAGCATCCAGCTCTGAAGATTACTCGTCGCTATGCCTTCGCTCACATCCTCACTGTCCTACAGTGTGCTACGGTCATTG
GCTTTTCCTACTGGGCTTCTGAGCTCATCCTGGCCCAGCAGCAACAGCATAAGAAGTACCACGGCTCCCAAGTCTATGTCACCTTTGCTGTTAGCTTCTACCTGGTGGCAGGAGCTGGCGGAGCCTCA
ATCCTGGCTACTGCAGCCAACCTCCTGCGCCACTATCCAACAGAGGAAGAAGAACAAGCACTGGAGCTGCTATCTGAGATGGAGGAGAATGACCCCTACCCAGCAGAGTATGAGGTCATCAACCAATT
CCAGCCACCCCCTGCCTACACACCATAATGCCAGCAGGGGCTCTCTTCCTCAGCAGCCCTTCCCCCCAGTGCCACAGCTCCTTTTATACCCAGAGGAGCCACTTCCCCCAGCAGGTCTCACCTGTAGG
ACCCTGACCATCTTCACCAAACCTTCTCCAGGAGACACTCTGCCTTTAGGCTTGTCCATGTGTCCCTGCTCTGCAGAGCTGGGACTCTGATTTTATATAATGTACTCTTTCCCTCCCAGCACCCTCTG
CTCCTTTCCTATTCACTAGCTCCTTCCAACCAGGGATGGTCAGATAAGTTTCCTCTCCTTGGGTTGCTGCTGGTAGTGGCCAGTCCCTAAGAGAGGTACCAACAGAGCACAAGGGGAAGGGACTGTGC
CATGCAGGTTCACTTTGCCAGGCCCAGCATTTGTGCCACTTGTGTATCTCTGGGCTGATCCCTCTTTTCTTCTAGAGTGCCCAGGCCCAGCCATCCACATTGTGGATTCTCTGCACTTTAGTCTCCAG
GCCACTCCTCATGTGTGTTCTGGTTTTCTGGAGAGAAGGAATCACTGCTGGGGAGCAATACAACTGTTCTCCTGCCCGGCCCTGGCTTCCTGTGGTTAGAACCAGGCAAGGAAGCAGAACCAGACAAG
AGACTGACTCTTTTGAGGACCCCAGTGAAGGGGGCTGAGTGCCCTAGCCCCTTCACCTTTTAATGTGAGTGGTTTTGAAAGGAGAAAAACAAAACCAAGCAATAGCAGCCATACTCTCTTTCTAAAAC
AGGGATAAAGCTGCTGTTGTTCAGAAATGTAGCCCATCCTTTATGGCTCTGCAATATTTTGGACCATAGCTCCCTCTGAGCCTATAGTCACGCCTCCCAGTCTCCAACAGAATGCAGGCTTTCTGTCC
TGGCTCCTTCTTCCAGGCAGCTGTGGCTCCCTGGGGCCTTTCTGTGGAACTAGGGCCACATGGCCCCCACGGGGCTGAGAACTATGGCCTGGCTGGCTGGCCAGCGTGGTGCTCCTCAGAACTGTGGC
ACTGAGATGTAACCTGGCCTCAGTTCAGGGACAGGGGGCCAAGTAGGGCAGGACCCTCCACTCTCCACACAGGTACTCCACCCAGAGGCCCAATAGGTTGGTGTCAGGACCCTGTCAGATGTGCAGGC
CTGGCTGTAGCCTTCAGAGTCAATGTGGCCCTAGACTGTGACTTGGGGCTACAGCTTGCTGCATGCCCCTCTCCCGTTCTGGAATGTATGCTGGTCTTGTGGTGTGCTACTGGGCTGTTACTCTAGCT
ATTCTGTTTGCCTTGGGTCCAGTTTTTTTTGGGGGGTGGGGGGTGTTTTTTTTTCCCCCTGGAGATCTGGGGCATAAGGTAGGTGAGACCTGAGAGGCCTGCAGCATGGATCCAGGTAGGCAAGCTGT
TCTTGTTCAGTTATGAGCTTCTCTGGAGTAAGAGTCTAGTGCTAACTGAAGGGAAAATGAATCCCAATCTCCTACCACCCATAAGACAACAGACATTTTGAACAAGAATGGAGAATGAATACAGTTGT
TGAACTGTGACTACAAGAAGACTGTCAACTCCCCATTCTTTGGCCAGAAAGAGTGGTGAATATGTGGACAAATGCCTATGCAGATGAAGACCAAGTGTGCCCATAAGAAAGCATCTGCCTGGAGTTCC
CTGCTGTAATGCCAAAGTGTGCCCCAGGATGACTCTCCCATTCTTCAGACCCCTCTCTGAGGCAAGAAAGGCTGCCAGGTGATGCCTGAGCACAGAATCAAGGGGCTAAGTTATGACTGCCTGTCTGA
TGTTCTGAGCTCATCATAGACAGGCTTCTGGTGTGTGTCCAGCTCTCTAACATGGCACCTGAGGGAGCAGGCCAGAAGTCCAGCACCAAACATGCATGCCAAAGTGAATGAGGACTGGACCCTGTGGA
CCGTTCCTTGTGATTTGGAACCCACTTTTTACTAGCTTCCCGTTCCTCTGGCCTTTCTCTTTTCCCTGCCATTCTCACACTGGTAGTTTGTCATATAGATTACTCTGGTTGTGTTTTTCTTTTCTAGG
GAAAAAATTAAAAGGCAAAACAAAAACCAGGAACTACAAATGAGAATGCAAATGCCAGTGGCTGACTGTCATTTTTGTCACAATTTTCCAGATGTTTGTTCTCTTCCTCTCAGAGAAGCAGAAGGCAT
TCACTGATGAAGCTTGTAATATGGAGCAGAGGTAGGAGGGACTTGGCATGCGCCTGCAACACGCACAACATTTTGGTCCTTGGGAGCCTCCCATTCCTGACACCTTTCACAGAGGAAGTTCTCAAAGC
CCACAGCTAGAAACAGTAGGTGGCTGTGCCCAAAATCTCAGTTCCAGACCTTGAGCTGCCTCTCTGCATGTCCTGATTAGCTGCAGAAGAGATGTTTCAGACCTCTACTGGTACTTACTGGGAGAAGC
CTGAAAATAAAAATGACTCTGGGAGCAAGACCTGCGGTCACTCTCCAGGCAGTTGTTGGGTGAAACCTTGATGGCTACCCACACTTTTAGTTCATTCATTCTCAACCCACGCACTGGACCCCAAGTGT
GTGAAAACATTTAGGGCTCTCTTTGGCAAGTGTTCCATTCCTAGCAGGATGCATGTCTTTCCTGGAAACTGATAATCTTCTCCTTATGTGTCCACTCACACATGTCTAAGAAGGGTCCATTGGATTAT
GCACAAAACACTGAGCCCCATGAAAGAAATAGGAAGACTGACAGGACCCTCTCTCCTAGGACTTACTTAGCCCAGGAGACAGACTCAGCCACAAGGAAACAGTGAAATGAGTAGTCTCCTGGACACGT
TGGGAAAGCCCTATGCTAGAAATGGGAGGCTGGATCTAACCAGAATAATTACTAACATCTTCCAGGTGGGGAGCCTGGGTTGTGTGGGAGAGCATTTCAGGGAGGGGCTGTTCCCTCTGAGGGAATGG
CAATAGTGGTCAGGATGTGCTGTGAAGTGGGATGGTGCAGACCCATCTAATGTTCCTCAAAGCAATGGGAAGCCATAGGAGGGCGCTAAAAGAAAAGGGGATCCAGTTTTATGGTGAGGTGGAGGGGC
TGCTGATACTAAGAAAAGCACCTGAGAGTGTGAGAATTGGGGGGCAGGTATACATTGGAGGACCCTCAGGCCTGGTAAGAGGAGGAAAGAATGATCACAGCTAGGTGCTGGGGTAGAGAACCCAGGAT
CTCCATCCCTGTCATATGCACTAGAAGATGGGATCAGCCTTGTAACTCAAGCGTGCCTCAAAAAGAGAGCTGTGTTGGGTAAGGACAGCAAAGACAAGCCTTTGAAAACACAAAGTGACTGATGTACC
TAGAGGAAAGGCCGTTCTGTCTAGATTATTCTCACTCAGAGGTGCCTGTGCCCTGGGCCAGGACAGTATGGAATATAAAGTTCTGTGGGGAGACAAAAAAGAACTAATAAACTTTATATAGCCTTTGT
TTTCAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039104991 ⟹ XP_038960919

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,919,416 - 134,932,210 (+)	NCBI
mRatBN7.2	3	114,466,095 - 114,478,894 (+)	NCBI


Protein RefSeqs	NP_001094448	(Get FASTA)	NCBI Sequence Viewer
	XP_038960919	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI31851	(Get FASTA)	NCBI Sequence Viewer
	EDL80110	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000097003.1
	ENSRNOP00000102251

RefSeq Acc Id:

NP_001094448 ⟸ NM_001100978

- UniProtKB:

A2RRU2 (UniProtKB/TrEMBL), A0A8I6AS31 (UniProtKB/TrEMBL), A6HQ09 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYAPGGAGLPGGRRRRSPGSSALPKQPERSLASALPGALSITALCTALAEPAWLHIHGGTCSRQELGVSDVLGYVHPDLLKDFCMNPQTVLLLRVIAAFCFLGILCSLSAFLLDVFGPKHPALKITRR
YAFAHILTVLQCATVIGFSYWASELILAQQQQHKKYHGSQVYVTFAVSFYLVAGAGGASILATAANLLRHYPTEEEEQALELLSEMEENDPYPAEYEVINQFQPPPAYTP

hide sequence

Ensembl Acc Id:

ENSRNOP00000030631 ⟸ ENSRNOT00000031577

RefSeq Acc Id:	XP_038960919 ⟸ XM_039104991
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000097003 ⟸ ENSRNOT00000117496

Protein Domains

Transmembrane protein 127 transmembrane region

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A2RRU2-F1-model_v2	AlphaFold	A2RRU2	1-238	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13692400

Promoter ID:

EPDNEW_R2925

Type:

initiation region

Name:

Tmem127_1

Description:

transmembrane protein 127

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	119,677,596 - 119,677,656	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-47999	BioCyc
Ensembl Genes	ENSRNOG00000022727	Ensembl
	ENSRNOG00000071101	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00000088819	ENTREZGENE
Ensembl Transcript	ENSRNOT00000117496.1	UniProtKB/TrEMBL
	ENSRNOT00000150685	ENTREZGENE
IMAGE_CLONE	IMAGE:7125680	IMAGE-MGC_LOAD
InterPro	TMEM127	UniProtKB/TrEMBL
	TMEM127_TM	UniProtKB/TrEMBL
KEGG Report	rno:311405	UniProtKB/TrEMBL
MGC_CLONE	MGC:156781	IMAGE-MGC_LOAD
NCBI Gene	311405	ENTREZGENE
PANTHER	PTHR28358	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 127	UniProtKB/TrEMBL
Pfam	TMEM127	UniProtKB/TrEMBL
PhenoGen	Tmem127	PhenoGen
RatGTEx	ENSRNOG00000022727	RatGTEx
	ENSRNOG00000071101	RatGTEx
	ENSRNOG00000088819	RatGTEx
UniProt	A0A8I6AS31	ENTREZGENE, UniProtKB/TrEMBL
	A2RRU2	ENTREZGENE, UniProtKB/TrEMBL
	A6HQ09	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-01-14	Tmem127	transmembrane protein 127	RGD1309744	similar to hypothetical protein FLJ20507	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1309744	similar to hypothetical protein FLJ20507	RGD1309744_predicted	similar to hypothetical protein FLJ20507 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1309744_predicted	similar to hypothetical protein FLJ20507 (predicted)	LOC311405_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC311405_predicted	similar to hypothetical protein FLJ20507 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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