Tmem127 (transmembrane protein 127) - Rat Genome Database

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Gene: Tmem127 (transmembrane protein 127) Heterocephalus glaber
Analyze
Symbol: Tmem127
Name: transmembrane protein 127
RGD ID: 18927248
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN endosome organization (ortholog); regulation of TOR signaling (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); acute promyelocytic leukemia (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); early endosome (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,333,472 - 2,344,674 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,333,472 - 2,344,652 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Tmem127
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,333,472 - 2,344,674 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,333,472 - 2,344,652 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TMEM127
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38296,248,514 - 96,265,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl296,248,500 - 96,266,047 (-)EnsemblGRCh38hg38GRCh38
GRCh37296,914,252 - 96,931,735 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,280,039 - 96,295,459 (-)NCBINCBI36Build 36hg18NCBI36
Celera291,357,500 - 91,372,939 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef290,877,443 - 90,893,248 (-)NCBIHuRef
CHM1_1296,920,300 - 96,936,106 (-)NCBICHM1_1
T2T-CHM13v2.0296,755,122 - 96,772,605 (-)NCBIT2T-CHM13v2.0
Tmem127
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,089,868 - 127,103,028 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,089,828 - 127,103,027 (+)EnsemblGRCm39 Ensembl
GRCm382127,247,904 - 127,261,108 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,247,908 - 127,261,107 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,073,711 - 127,086,500 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362126,939,416 - 126,952,205 (+)NCBIMGSCv36mm8
Celera2128,487,347 - 128,500,147 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.87NCBI
Tmem127
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83134,919,416 - 134,932,210 (+)NCBIGRCr8
mRatBN7.23114,466,095 - 114,478,894 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,466,171 - 114,477,519 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3118,357,660 - 118,370,450 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03126,953,204 - 126,965,994 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,613,584 - 124,626,374 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,677,575 - 119,690,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,677,575 - 119,690,366 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,202,774 - 126,215,589 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,746,454 - 114,759,251 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13114,652,049 - 114,664,824 (+)NCBI
Celera3113,306,634 - 113,319,570 (+)NCBICelera
Cytogenetic Map3q36NCBI
Tmem127
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,808,455 - 3,822,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554703,809,835 - 3,822,442 (-)NCBIChiLan1.0ChiLan1.0
TMEM127
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21232,042,817 - 32,057,217 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A32,045,577 - 32,059,977 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A103,049,655 - 103,065,116 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A97,174,322 - 97,189,177 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A97,174,322 - 97,189,171 (-)Ensemblpanpan1.1panPan2
TMEM127
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,512,753 - 34,527,208 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,512,792 - 34,523,692 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1734,282,678 - 34,295,473 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01735,283,964 - 35,296,760 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1735,283,938 - 35,296,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11734,413,107 - 34,426,110 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01734,481,752 - 34,494,521 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01734,688,570 - 34,701,364 (+)NCBIUU_Cfam_GSD_1.0
Tmem127
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,091,414 - 83,106,154 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744344,356 - 359,044 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936744344,356 - 359,086 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM127
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl346,966,892 - 46,978,810 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1346,966,858 - 47,017,659 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,108,738 - 49,121,833 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM127
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114671,259 - 685,217 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14673,375 - 685,228 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041168,096,788 - 168,111,829 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012667   ⟹   ENSHGLP00000012531
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247492,333,472 - 2,344,674 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000012668   ⟹   ENSHGLP00000012532
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247492,333,472 - 2,344,674 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000012669   ⟹   ENSHGLP00000012533
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247492,335,395 - 2,344,674 (-)Ensembl
RefSeq Acc Id: XM_004844353   ⟹   XP_004844410
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247492,333,472 - 2,344,652 (-)NCBI
RefSeq Acc Id: XR_002394754
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247492,333,472 - 2,344,652 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004844410 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10622 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012533
  ENSHGLP00100030135
GenBank Protein JAO02854 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004844410   ⟸   XM_004844353
- UniProtKB: G5BMW1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000012532   ⟸   ENSHGLT00000012668
Ensembl Acc Id: ENSHGLP00000012531   ⟸   ENSHGLT00000012667
Ensembl Acc Id: ENSHGLP00000012533   ⟸   ENSHGLT00000012669


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008960 Ensembl, ENTREZGENE
  ENSHGLG00100032998 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000012669 ENTREZGENE
  ENSHGLT00100062160 UniProtKB/TrEMBL
InterPro TMEM127 UniProtKB/TrEMBL
  TMEM127_TM UniProtKB/TrEMBL
KEGG Report hgl:101702991 UniProtKB/TrEMBL
NCBI Gene Tmem127 ENTREZGENE
PANTHER PTHR28358 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 127 UniProtKB/TrEMBL
Pfam TMEM127 UniProtKB/TrEMBL
UniProt G5BMW1 ENTREZGENE, UniProtKB/TrEMBL