Papss1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) - Rat Genome Database

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Gene: Papss1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) Rattus norvegicus
Analyze
Symbol: Papss1
Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 1
RGD ID: 1308081
Description: Predicted to enable adenylylsulfate kinase activity; protein homodimerization activity; and sulfate adenylyltransferase (ATP) activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Orthologous to human PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1); PARTICIPATES IN selenoamino acid metabolic pathway; purine metabolic pathway; sulfur metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; LOC295443
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82222,646,103 - 222,788,475 (+)NCBIGRCr8
mRatBN7.22220,040,343 - 220,114,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2220,040,312 - 220,114,395 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2227,694,669 - 227,769,811 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02225,594,371 - 225,669,512 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02220,451,980 - 220,527,122 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02236,605,695 - 236,680,772 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,605,695 - 236,680,772 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02255,150,454 - 255,224,840 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42229,005,799 - 229,040,958 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12228,889,020 - 229,027,522 (+)NCBI
Celera2212,293,970 - 212,366,124 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-octylphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
Aroclor 1254  (ISO)
arsenic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
Diisodecyl phthalate  (ISO)
diuron  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
glafenine  (EXP)
glycidyl methacrylate  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
L-1,4-dithiothreitol  (ISO)
L-ascorbic acid  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
molybdate  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perchlorate  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
selenic acid  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungstate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12414806   PMID:12477932   PMID:14747722   PMID:23207770  


Genomics

Comparative Map Data
Papss1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82222,646,103 - 222,788,475 (+)NCBIGRCr8
mRatBN7.22220,040,343 - 220,114,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2220,040,312 - 220,114,395 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2227,694,669 - 227,769,811 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02225,594,371 - 225,669,512 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02220,451,980 - 220,527,122 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02236,605,695 - 236,680,772 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,605,695 - 236,680,772 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02255,150,454 - 255,224,840 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42229,005,799 - 229,040,958 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12228,889,020 - 229,027,522 (+)NCBI
Celera2212,293,970 - 212,366,124 (+)NCBICelera
Cytogenetic Map2q43NCBI
PAPSS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384107,613,666 - 107,720,234 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4107,590,276 - 107,720,234 (-)EnsemblGRCh38hg38GRCh38
GRCh374108,534,822 - 108,641,390 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364108,754,271 - 108,860,868 (-)NCBINCBI36Build 36hg18NCBI36
Build 344108,892,426 - 108,999,023NCBI
Celera4105,829,640 - 105,936,231 (-)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4104,266,753 - 104,373,278 (-)NCBIHuRef
CHM1_14108,511,323 - 108,617,917 (-)NCBICHM1_1
T2T-CHM13v2.04110,915,973 - 111,022,538 (-)NCBIT2T-CHM13v2.0
Papss1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393131,270,626 - 131,349,432 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3131,270,529 - 131,349,432 (+)EnsemblGRCm39 Ensembl
GRCm383131,564,764 - 131,643,671 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3131,564,768 - 131,643,671 (+)EnsemblGRCm38mm10GRCm38
MGSCv373131,227,732 - 131,306,635 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363131,502,197 - 131,580,977 (+)NCBIMGSCv36mm8
Celera3137,997,596 - 138,077,551 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map361.05NCBI
Papss1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554961,993,172 - 2,059,174 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554961,993,423 - 2,057,384 (+)NCBIChiLan1.0ChiLan1.0
PAPSS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23105,712,866 - 105,819,249 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14106,007,794 - 106,113,928 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04100,119,540 - 100,225,575 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14110,692,601 - 110,798,589 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4110,692,601 - 110,798,619 (-)Ensemblpanpan1.1panPan2
PAPSS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13228,136,741 - 28,235,529 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3228,136,909 - 28,235,484 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3213,786,487 - 13,885,180 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03228,366,674 - 28,465,600 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3228,366,674 - 28,465,638 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13228,360,120 - 28,458,995 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03228,104,488 - 28,203,414 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03211,654,297 - 11,753,135 (+)NCBIUU_Cfam_GSD_1.0
Papss1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530112,894,769 - 13,006,269 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936818864,180 - 974,989 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936818863,969 - 975,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAPSS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8114,252,416 - 114,373,427 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18114,252,059 - 114,369,309 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28122,548,837 - 122,549,561 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAPSS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1755,545,835 - 55,650,311 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl755,545,616 - 55,650,206 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603734,171,401 - 34,275,633 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Papss1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248301,577,681 - 1,636,476 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248301,582,240 - 1,636,349 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Papss1
366 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:67
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000015077
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
2299161Iddm33Insulin dependent diabetes mellitus QTL 332.98blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2206312063220876787Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2219753301226277316Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat

Markers in Region
RH129187  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22220,114,160 - 220,114,346 (+)MAPPERmRatBN7.2
Rnor_6.02236,680,538 - 236,680,723NCBIRnor6.0
Rnor_5.02255,224,606 - 255,224,791UniSTSRnor5.0
RGSC_v3.42229,040,724 - 229,040,909UniSTSRGSC3.4
Celera2212,365,890 - 212,366,075UniSTS
RH 3.4 Map21547.7UniSTS
Cytogenetic Map2q43UniSTS
Papss1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22220,113,737 - 220,113,952 (+)MAPPERmRatBN7.2
Rnor_6.02236,680,115 - 236,680,329NCBIRnor6.0
Rnor_5.02255,224,183 - 255,224,397UniSTSRnor5.0
RGSC_v3.42229,040,301 - 229,040,515UniSTSRGSC3.4
Celera2212,365,467 - 212,365,681UniSTS
Cytogenetic Map2q43UniSTS
G46408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22220,077,542 - 220,077,760 (+)MAPPERmRatBN7.2
Rnor_6.02236,643,521 - 236,643,738NCBIRnor6.0
Rnor_5.02255,187,589 - 255,187,806UniSTSRnor5.0
RGSC_v3.42229,004,112 - 229,004,329UniSTSRGSC3.4
Celera2212,329,293 - 212,329,510UniSTS
Cytogenetic Map2q43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 38 22 19 22 2 2 74 35 35 11 2
Low 14 19 19 19 6 9 6 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015077   ⟹   ENSRNOP00000015077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2220,040,312 - 220,114,392 (+)Ensembl
Rnor_6.0 Ensembl2236,605,695 - 236,680,772 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081248   ⟹   ENSRNOP00000075620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2220,061,910 - 220,114,395 (+)Ensembl
Rnor_6.0 Ensembl2236,625,357 - 236,680,771 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085301   ⟹   ENSRNOP00000071489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2220,040,312 - 220,114,392 (+)Ensembl
Rnor_6.0 Ensembl2236,605,758 - 236,680,206 (+)Ensembl
RefSeq Acc Id: NM_001395059   ⟹   NP_001381988
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82222,714,430 - 222,788,475 (+)NCBI
mRatBN7.22220,040,343 - 220,114,399 (+)NCBI
RefSeq Acc Id: XM_063281662   ⟹   XP_063137732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82222,646,103 - 222,788,471 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001381988 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137732 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66793 (Get FASTA)   NCBI Sequence Viewer  
  EDL82217 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015077.7
  ENSRNOP00000071489
  ENSRNOP00000071489.2
  ENSRNOP00000075620.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000071489   ⟸   ENSRNOT00000085301
RefSeq Acc Id: ENSRNOP00000075620   ⟸   ENSRNOT00000081248
RefSeq Acc Id: ENSRNOP00000015077   ⟸   ENSRNOT00000015077
RefSeq Acc Id: NP_001381988   ⟸   NM_001395059
- UniProtKB: A0A0G2K0L0 (UniProtKB/TrEMBL),   B2RYI8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137732   ⟸   XM_063281662
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0L0 (UniProtKB/TrEMBL)
Protein Domains
ATP-sulfurylase PUA-like   Sulphate adenylyltransferase catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0L0-F1-model_v2 AlphaFold A0A0G2K0L0 1-623 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691762
Promoter ID:EPDNEW_R2286
Type:initiation region
Name:Papss1_1
Description:3'-phosphoadenosine 5'-phosphosulfate synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02236,605,701 - 236,605,761EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308081 AgrOrtholog
BioCyc Gene G2FUF-51190 BioCyc
Ensembl Genes ENSRNOG00000011311 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015077.8 UniProtKB/TrEMBL
  ENSRNOT00000081248.2 UniProtKB/TrEMBL
  ENSRNOT00000085301 ENTREZGENE
  ENSRNOT00000085301.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  3.40.50.620 UniProtKB/TrEMBL
  Sulfate adenylyltransferase UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7937610 IMAGE-MGC_LOAD
InterPro APS_kinase UniProtKB/TrEMBL
  ATP-Sase_PUA-like_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PUA-like UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
  Sulfurylase_cat_dom UniProtKB/TrEMBL
  Sulphate_adenylyltransferase UniProtKB/TrEMBL
MGC_CLONE MGC:188588 IMAGE-MGC_LOAD
NCBI Gene 295443 ENTREZGENE
PANTHER BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE UniProtKB/TrEMBL
  BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1 UniProtKB/TrEMBL
Pfam APS_kinase UniProtKB/TrEMBL
  ATP-sulfurylase UniProtKB/TrEMBL
  PUA_2 UniProtKB/TrEMBL
PhenoGen Papss1 PhenoGen
RatGTEx ENSRNOG00000011311 RatGTEx
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
  PUA-like UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2K0L0 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KB21_RAT UniProtKB/TrEMBL
  B2RYI8 ENTREZGENE, UniProtKB/TrEMBL
  F1LX70_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Papss1  3'-phosphoadenosine 5'-phosphosulfate synthase 1   Papss1_predicted  3'-phosphoadenosine 5'-phosphosulfate synthase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Papss1_predicted  3'-phosphoadenosine 5'-phosphosulfate synthase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED