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Gene: Capn12 (calpain 12) Rattus norvegicus

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Symbol:

Capn12

Name:

calpain 12

RGD ID:

1307341

Description:

Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Orthologous to human CAPN12 (calpain 12); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

calpain-12; LOC308476

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CAPN12 (calpain 12)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Capn12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Capn12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CAPN12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CAPN12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Capn12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CAPN12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CAPN12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Capn12 (calpain 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CAPN12 (calpain 12)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Capn12 (calpain 12)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	capn12 (calpain 12)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Caenorhabditis elegans (roundworm):	clp-7	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	clp-6	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	XB5844015 [provisional:capn2]	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	93,298,571 - 93,311,220 (+)	NCBI		GRCr8
mRatBN7.2	1	84,171,059 - 84,183,161 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	84,171,059 - 84,183,119 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	89,580,975 - 89,593,038 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	98,040,078 - 98,052,143 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	91,336,837 - 91,348,901 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	87,066,289 - 87,078,348 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	87,066,289 - 87,078,348 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	88,246,907 - 88,258,966 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	83,989,000 - 84,001,059 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	84,066,985 - 84,078,502 (+)	NCBI
Celera	1	78,561,187 - 78,573,226 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Capn12	Rat	maturity-onset diabetes of the young type 1		ISO	RGD:1316482	8554872	ClinVar Annotator: match by term: Type 2 diabetes mellitus	ClinVar	PMID:28492532
Capn12	Rat	type 2 diabetes mellitus		ISO	RGD:1316482	8554872	ClinVar Annotator: match by term: Type 2 diabetes mellitus	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Capn12	Rat	17alpha-ethynylestradiol	increases expression	EXP		6480464	Ethinyl Estradiol results in increased expression of CAPN12 mRNA	CTD	PMID:17557909
Capn12	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:1316483	6480464	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CAPN12 promoter]	CTD	PMID:19654925
Capn12	Rat	4,4'-diaminodiphenylmethane	increases expression	ISO	RGD:1316483	6480464	4,4'-diaminodiphenylmethane results in increased expression of CAPN12 mRNA	CTD	PMID:18648102
Capn12	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	RGD:1316483	6480464	bisphenol S results in decreased methylation of CAPN12 exon	CTD	PMID:33297965
Capn12	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	RGD:1316483	6480464	bisphenol S affects the methylation of CAPN12 gene	CTD	PMID:31683443
Capn12	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of CAPN12 mRNA	CTD	PMID:25825206
Capn12	Rat	aflatoxin B1	decreases expression	ISO	RGD:1316482	6480464	Aflatoxin B1 results in decreased expression of CAPN12 mRNA	CTD	PMID:27153756
Capn12	Rat	aflatoxin B1	decreases methylation	ISO	RGD:1316482	6480464	Aflatoxin B1 results in decreased methylation of CAPN12 intron	CTD	PMID:30157460
Capn12	Rat	aristolochic acid A	increases expression	ISO	RGD:1316482	6480464	aristolochic acid I results in increased expression of CAPN12 mRNA	CTD	PMID:33212167
Capn12	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1316482	6480464	Benzo(a)pyrene results in increased methylation of CAPN12 promoter	CTD	PMID:27901495
Capn12	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1316482	6480464	Benzo(a)pyrene results in decreased expression of CAPN12 mRNA	CTD	PMID:32234424
Capn12	Rat	bis(2-chloroethyl) sulfide	increases expression	ISO	RGD:1316482	6480464	Mustard Gas results in increased expression of CAPN12 mRNA	CTD	PMID:25102026
Capn12	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of CAPN12 mRNA	CTD	PMID:25181051
Capn12	Rat	bisphenol A	decreases methylation	ISO	RGD:1316482	6480464	bisphenol A results in decreased methylation of CAPN12 gene	CTD	PMID:31601247
Capn12	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of CAPN12 mRNA	CTD	PMID:31129395
Capn12	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with tributyltin] results in decreased expression of CAPN12 mRNA	CTD	PMID:31129395
Capn12	Rat	bisphenol F	decreases expression	ISO	RGD:1316483	6480464	bisphenol F results in decreased expression of CAPN12 mRNA	CTD	PMID:38685157
Capn12	Rat	cadmium dichloride	decreases expression	ISO	RGD:1316482	6480464	Cadmium Chloride results in decreased expression of CAPN12 mRNA	CTD	PMID:38382870
Capn12	Rat	calcitriol	increases expression	ISO	RGD:1316482	6480464	Calcitriol results in increased expression of CAPN12 mRNA	CTD	PMID:21592394
Capn12	Rat	calcitriol	multiple interactions	ISO	RGD:1316482	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of CAPN12 mRNA	CTD	PMID:21592394
Capn12	Rat	carbamazepine	affects expression	ISO	RGD:1316482	6480464	Carbamazepine affects the expression of CAPN12 mRNA	CTD	PMID:25979313
Capn12	Rat	chlordecone	increases expression	ISO	RGD:1316483	6480464	Chlordecone results in increased expression of CAPN12 mRNA	CTD	PMID:33711761
Capn12	Rat	cyclosporin A	increases expression	ISO	RGD:1316482	6480464	Cyclosporine results in increased expression of CAPN12 mRNA	CTD	PMID:27989131
Capn12	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1316482	6480464	di-n-butylphosphoric acid affects the expression of CAPN12 mRNA	CTD	PMID:37042841
Capn12	Rat	doxorubicin	increases expression	ISO	RGD:1316482	6480464	Doxorubicin results in increased expression of CAPN12 mRNA	CTD	PMID:29803840
Capn12	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of CAPN12 mRNA	CTD	PMID:33387578
Capn12	Rat	glyphosate	increases methylation	EXP		6480464	Glyphosate results in increased methylation of CAPN12 gene	CTD	PMID:31011160
Capn12	Rat	GSK-J4	decreases expression	ISO	RGD:1316482	6480464	GSK-J4 results in decreased expression of CAPN12 mRNA	CTD	PMID:29301935
Capn12	Rat	okadaic acid	decreases expression	ISO	RGD:1316482	6480464	Okadaic Acid results in decreased expression of CAPN12 mRNA	CTD	PMID:38832940
Capn12	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of CAPN12 mRNA	CTD	PMID:33387578
Capn12	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	RGD:1316483	6480464	perfluorohexanesulfonic acid results in decreased expression of CAPN12 mRNA	CTD	PMID:37995155
Capn12	Rat	propanal	increases expression	ISO	RGD:1316482	6480464	propionaldehyde results in increased expression of CAPN12 mRNA	CTD	PMID:26079696
Capn12	Rat	sodium arsenite	decreases expression	ISO	RGD:1316482	6480464	sodium arsenite results in decreased expression of CAPN12 mRNA	CTD	PMID:34032870
Capn12	Rat	sodium arsenite	decreases expression	ISO	RGD:1316483	6480464	sodium arsenite results in decreased expression of CAPN12 mRNA	CTD	PMID:37682722
Capn12	Rat	sotorasib	multiple interactions	ISO	RGD:1316482	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CAPN12 mRNA	CTD	PMID:36139627
Capn12	Rat	testosterone	multiple interactions	ISO	RGD:1316482	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of CAPN12 mRNA	CTD	PMID:21592394
Capn12	Rat	testosterone	increases expression	ISO	RGD:1316482	6480464	Testosterone results in increased expression of CAPN12 mRNA	CTD	PMID:21592394
Capn12	Rat	trametinib	multiple interactions	ISO	RGD:1316482	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of CAPN12 mRNA	CTD	PMID:36139627
Capn12	Rat	tributylstannane	multiple interactions	EXP		6480464	[bisphenol A co-treated with tributyltin] results in decreased expression of CAPN12 mRNA	CTD	PMID:31129395
Capn12	Rat	valproic acid	affects expression	ISO	RGD:1316483	6480464	Valproic Acid affects the expression of CAPN12 mRNA	CTD	PMID:17292431
Capn12	Rat	valproic acid	affects expression	ISO	RGD:1316482	6480464	Valproic Acid affects the expression of CAPN12 mRNA	CTD	PMID:25979313

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Capn12	Rat	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Capn12	Rat	proteolysis	involved_in	IEA	InterPro:IPR001300\|InterPro:IPR022684	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Capn12	Rat	proteolysis	involved_in	IBA	FB:FBgn0012051\|FB:FBgn0025866\|MGI:107437\|MGI:2181366\|MGI:88263\|MGI:88264\|PANTHER:PTN000021568\|RGD:2267\|RGD:2268\|RGD:2269\|UniProtKB:P07384\|UniProtKB:P17655\|UniProtKB:P20807\|UniProtKB:Q9HC96\|WB:WBGene00006606	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Capn12	Rat	cytoplasm	is_active_in	IBA	FB:FBgn0012051\|FB:FBgn0025866\|FB:FBgn0260450\|MGI:107437\|MGI:1352490\|MGI:88263\|MGI:88264\|PANTHER:PTN000021568\|RGD:2268\|RGD:2269\|RGD:69354\|UniProtKB:P07384\|UniProtKB:P17655\|UniProtKB:P20807\|UniProtKB:Q9HC96\|UniProtKB:Q9Y6Q1\|WB:WBGene00000542	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Capn12	Rat	calcium ion binding	enables	IEA	InterPro:IPR002048	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Capn12	Rat	calcium-dependent cysteine-type endopeptidase activity	enables	IBA	FB:FBgn0012051\|FB:FBgn0025866\|MGI:107437\|MGI:2181366\|MGI:88263\|MGI:88264\|PANTHER:PTN000021568\|RGD:2267\|RGD:2269\|RGD:69354\|UniProtKB:P07384\|UniProtKB:P17655\|UniProtKB:Q9HC96	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Capn12	Rat	calcium-dependent cysteine-type endopeptidase activity	enables	IEA	InterPro:IPR001300\|InterPro:IPR022684	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Capn12	Rat	cysteine-type peptidase activity	enables	IEA	UniProtKB-KW:KW-0788	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Capn12	Rat	cysteine-type peptidase activity	enables	IEA	UniRule:UR000413271	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Capn12	Rat	hydrolase activity	enables	IEA	UniRule:UR000413271	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Capn12	Rat	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Capn12	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Capn12	Rat	peptidase activity	enables	IEA	UniRule:UR000413271	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Capn12	Rat	peptidase activity	enables	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Capn12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	93,298,571 - 93,311,220 (+)	NCBI		GRCr8
mRatBN7.2	1	84,171,059 - 84,183,161 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	84,171,059 - 84,183,119 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	89,580,975 - 89,593,038 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	98,040,078 - 98,052,143 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	91,336,837 - 91,348,901 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	87,066,289 - 87,078,348 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	87,066,289 - 87,078,348 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	88,246,907 - 88,258,966 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	83,989,000 - 84,001,059 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	84,066,985 - 84,078,502 (+)	NCBI
Celera	1	78,561,187 - 78,573,226 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

CAPN12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	38,730,192 - 38,744,693 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	38,730,187 - 38,769,904 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	39,220,832 - 39,235,114 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	43,912,672 - 43,926,954 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	43,912,671 - 43,926,954	NCBI
Celera	19	36,022,825 - 36,037,032 (-)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	35,667,615 - 35,682,075 (-)	NCBI		HuRef
CHM1_1	19	39,221,640 - 39,235,595 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	41,534,246 - 41,548,645 (-)	NCBI		T2T-CHM13v2.0

Capn12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	28,580,890 - 28,593,010 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	28,580,847 - 28,592,988 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	28,881,465 - 28,893,585 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	28,881,422 - 28,893,563 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	29,666,675 - 29,678,604 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	28,590,417 - 28,602,345 (+)	NCBI		MGSCv36	mm8
Celera	7	23,443,096 - 23,455,025 (+)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	16.94	NCBI

Capn12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	761,015 - 770,327 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	761,015 - 771,387 (+)	NCBI	ChiLan1.0	ChiLan1.0

CAPN12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	45,022,279 - 45,036,564 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	46,892,628 - 46,907,061 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	35,824,858 - 35,839,633 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	44,396,099 - 44,409,441 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	44,394,323 - 44,409,441 (-)	Ensembl	panpan1.1		panPan2

CAPN12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	114,342,210 - 114,347,873 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	114,342,521 - 114,354,482 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	113,747,505 - 113,759,624 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	114,944,822 - 114,956,873 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	114,942,987 - 114,956,640 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	114,518,101 - 114,530,073 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	114,135,462 - 114,147,615 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	115,174,114 - 115,186,160 (+)	NCBI		UU_Cfam_GSD_1.0

Capn12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	13,237,769 - 13,261,377 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936801	1,403,256 - 1,412,570 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936801	1,402,813 - 1,426,733 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAPN12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	47,565,440 - 47,578,994 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	47,565,917 - 47,579,278 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	43,126,499 - 43,139,839 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAPN12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	33,372,942 - 33,403,800 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	33,373,372 - 33,385,758 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	11,323,650 - 11,370,402 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Capn12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	12,113,970 - 12,124,499 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	12,114,392 - 12,125,633 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Capn12
41 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	67
Count of miRNA genes:	59
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000027645
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	72197680	90508767	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	83547917	128547917	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	50343510	99980958	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	78430754	91209302	Rat

RH130124

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	84,182,829 - 84,183,027 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	87,078,059 - 87,078,256	NCBI	Rnor6.0
Rnor_5.0	1	88,258,677 - 88,258,874	UniSTS	Rnor5.0
RGSC_v3.4	1	84,000,770 - 84,000,967	UniSTS	RGSC3.4
Celera	1	78,572,937 - 78,573,134	UniSTS
RH 3.4 Map	1	829.8	UniSTS
Cytogenetic Map	1	q22	UniSTS
Cytogenetic Map	1	q21	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	59	31


RefSeq Transcripts	NM_001110808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005505354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027645 ⟹ ENSRNOP00000027645

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	84,171,059 - 84,183,119 (+)	Ensembl
Rnor_6.0 Ensembl	1	87,066,289 - 87,078,348 (+)	Ensembl

RefSeq Acc Id:

NM_001110808 ⟹ NP_001104278

RefSeq Status:

INFERRED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	93,298,571 - 93,310,630 (+)	NCBI
mRatBN7.2	1	84,171,059 - 84,183,119 (+)	NCBI
Rnor_6.0	1	87,066,289 - 87,078,348 (+)	NCBI
Rnor_5.0	1	88,246,907 - 88,258,966 (+)	NCBI
RGSC_v3.4	1	83,989,000 - 84,001,059 (+)	RGD
Celera	1	78,561,187 - 78,573,226 (+)	RGD

Sequence:

show sequence

CCATGCTTAAAGACCCCCAACAGGGTACAAATGGAACAGAAGCCCCGCCTCATGACTCAGGAGGTTAAAGGGCTTGGGTCCTTCTGTGTGCCCAGAGTGTCCGGATGGCGAGTGGCAACAGGAAGGTC
ACTATCCAGCTGGTGGACGACGGGGCCGCGGCTGGAGCTGGGGGCCCACAGCTCTTTAAGGGTCAGAACTACGAAGCCATCCGAGCAGCTTGCCTGGATTCCGGGATCCTGTTTCGTGACCCTTGCTT
CCCTGCTGGCCCTGATGCCCTTGGCTATGACAAGCTGGGACCTGACTCAGAGAAGGCCAAAGGGGTGGAATGGAAGAGGCCTCATGAGTTTTGTGCCGAGCCCCAGTTCATCTGTGAAGACATGAGTA
GAACAGATGTGTGCCAGGGCAGCTTGGGAAACTGCTGGCTTCTAGCAGCGGCTGCCTCTCTCACGCTGTACCCCAGACTCCTGTACCGGGTGGTCCCCCCTGGGCAAGGCTTCCAAGATGGCTATGCT
GGGGTTTTCCACTTTCAGCTCTGGCAGTTTGGCCGATGGGTGGATGTGGTGGTGGACGACAAACTGCCTGTGCGTGACGGGAAGCTGCTCTTTGTGCGCTCAGAACAAAGGAACGAGTTCTGGGCCCC
TCTACTGGAAAAGGCCTATGCCAAGCTCCACGGCTCCTATGAGGTAATGCGAGGAGGTCACATGAACGAGGCATTTGTGGACTTTACGGGAGGCGTGGGCGAGGTCCTCTACTTGAGACAGAACACCC
CAGGTGTCTTTGCCGCCCTTCGCCATGCCCTGGCCAAGGAGTCCCTTGTGGGTGCCACTGCCCTGAGTGATCGGGGTGAGATCCGCACAGATGAAGGGCTTGTGAAAGGACATGCTTATTCTGTCACA
GGCACACACAAGATGTCTCTGGGCTTCACCAAGGTGCGGCTGCTGCGGCTGAGGAACCCCTGGGGCCGCGTGGAGTGGTCCGGGCCCTGGAGCGACAGCTGCCCACGCTGGGACATGCTCCCCTCTGA
GTGGAGAGATGCCCTGCTTGTGAAAAAGGAGGATGGCGAGTTCTGGATGGAGCTTCAGGACTTCCTCACGCACTTCAACACGGTCCAGATTTGTTCACTGAGCCCTGAGGTGTTGGGCCCCAGCCCGG
CTGGTGGCGGCTGGCACATTCACACCTTCCAGGGCCGCTGGGTGCGCGGCTTCAACTCCGGTGGGAGTCAGCCCAGCGCTGAAAACTTCTGGACCAATCCCCAGTTCCGGCTGACACTGCTGGAGCCG
GATGAGGAAGAGGATGAAGATGATGAAGAGGGACCCTGGGGAGGCTGGGGAGCTGCAGGGGCACGGCCAGCGAGAGGAGGCCGAGTCCCCAAGTGCACGGTCCTACTGTCACTCATCCAACGCAACCG
CCGGTGTCTGAGGGCCAAGGGCCTCACTTACCTCACTGTGGGCTTCCACGTGTTCCAGATCCCGGAGGAGCTGCTGGGCCTCTGGGACTCTCCGCGCAGCCGCGCGCTCTTACCGGGACTGCTGCGCG
CCGACCGCTCGGTTTTCTGTGCCCGCCGCGACGTGAGCCGACGCTGCCGCCTGCCGCCCGGCCACTACCTGGTGGTGCCCAGCGCCTCGCGCGTGGGCGATGAAGCCGACTTCACGCTGCGCATCTTC
TCGGAGCGCAGCCACACCGCAGTGGAGATCGATGACGTGATCAGCGCGGACCTGGACGCCCTCCAGGCCCCCTACAAGCCTCTGGAGCTGGAGTTGGCACAGCTATTTTTGGAGCTGGCTGGAGAGGA
GGAGGAGCTCAATGCTCTCCAGCTGCAGACCTTAATAAGCATTGCTCTGGAGCCTGCTAGGAACAACACCAGGACCTCTGGAGAGATTGGCCTTAGGACCTGCGAACAGCTTGTGCAGTGTTTTGGGC
GTGGGCAAAGATTGGCCCTATACCACTTCCAGGAACTCTGGGGCCATCTCCTGTCATGGCAGGCCACATTTGACAAGTTCGATGAAGATGCTTCTGGGACAATGAACTCCTGTGAACTGAGGCTGGCA
CTGACTGCCGCAGGCTTCCACCTGAACAACCAGCTGACCCAGGCTCTCACTAGCCGCTACCGAAACAGCCGGCTCCGCGTGGACTTCGAGCACTTTGTGTGTTGTGCAGCCCGGCTCACCTGCATCTT
CCGCCACTGCTGCCAACACCTGGATGGCGGCGAGGGGGTCGTCTGCCTGACCCACAAACAGTGGTCGGAGGTGGCCACCTTCTCATAGGCTTGAAGCTGAGGGAGTCTGCCCTGCTGCCCTGCTGCCC
TGCTTGGTGCCAGTGATGGAAGATGAACATGGATGAGCTCGGCTTGGGCCCAACTTGCTGTCACACAGGTGGAGGCTATGGTGTCTGTCTTCTGGCTATGTGGTCCTGGCTGGCCTCACAAGTGCTGG
GATTACGAGCTGGAGCTGTCCCAAACAGAACTGTCTTCCTTTTACAACTTGTGCATGTCAGTCCCTGCATGGAGGCCCATAAACCACACACAGGCACTGGGCCAGTGAGCACTGCAAGCTCCCTGGGG
AATGACGGGGACGCAGGGAGAAGATGACACCAGAGTCCTTCTTAAAAATATTACTTGTTTTATTCTCCCATCCCCAGAGGGTGGTTTATCCAGAAACCAAGAAAATAAAAATCAATCAGAATAAACTC
AAGGGGGTGGGTGGAGAGAAACCCATTAACGACCAGGCAGGCAGGCCAGCGCCCACCTCCACCTCAGGAGGTCCCCGTAGACCCCTGCCCACCGCCATAAGGGGAAAATCAGGAGGGGGCTGGGAGGG
CAGCGAATCAGCTATGTCTTCATTATGAGAGTGAGAGAGGTGGCAGAGATATGCAGCTAGATGGATATATATTTATATAATAAATCCGTAAGTTAATAAAGTAAATAGTAATTCTC

hide sequence

RefSeq Acc Id:

XM_039111580 ⟹ XP_038967508

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	93,298,675 - 93,311,220 (+)	NCBI
mRatBN7.2	1	84,171,134 - 84,183,161 (+)	NCBI

RefSeq Acc Id:

XM_039111581 ⟹ XP_038967509

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	93,298,675 - 93,309,709 (+)	NCBI
mRatBN7.2	1	84,171,134 - 84,182,198 (+)	NCBI

RefSeq Acc Id:

XR_005505354

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	93,298,675 - 93,309,826 (+)	NCBI
mRatBN7.2	1	84,171,134 - 84,182,315 (+)	NCBI


Protein RefSeqs	NP_001104278	(Get FASTA)	NCBI Sequence Viewer
	XP_038967508	(Get FASTA)	NCBI Sequence Viewer
	XP_038967509	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07864	(Get FASTA)	NCBI Sequence Viewer
	EDM07865	(Get FASTA)	NCBI Sequence Viewer
	EDM07866	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027645
	ENSRNOP00000027645.3

RefSeq Acc Id:

NP_001104278 ⟸ NM_001110808

- UniProtKB:

D3ZJZ8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASGNRKVTIQLVDDGAAAGAGGPQLFKGQNYEAIRAACLDSGILFRDPCFPAGPDALGYDKLGPDSEKAKGVEWKRPHEFCAEPQFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPPG
QGFQDGYAGVFHFQLWQFGRWVDVVVDDKLPVRDGKLLFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNTPGVFAALRHALAKESLVGATALSDRGEIRTDEGLV
KGHAYSVTGTHKMSLGFTKVRLLRLRNPWGRVEWSGPWSDSCPRWDMLPSEWRDALLVKKEDGEFWMELQDFLTHFNTVQICSLSPEVLGPSPAGGGWHIHTFQGRWVRGFNSGGSQPSAENFWTNPQ
FRLTLLEPDEEEDEDDEEGPWGGWGAAGARPARGGRVPKCTVLLSLIQRNRRCLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSRALLPGLLRADRSVFCARRDVSRRCRLPPGHYLVVPSASRVGDE
ADFTLRIFSERSHTAVEIDDVISADLDALQAPYKPLELELAQLFLELAGEEEELNALQLQTLISIALEPARNNTRTSGEIGLRTCEQLVQCFGRGQRLALYHFQELWGHLLSWQATFDKFDEDASGTM
NSCELRLALTAAGFHLNNQLTQALTSRYRNSRLRVDFEHFVCCAARLTCIFRHCCQHLDGGEGVVCLTHKQWSEVATFS

hide sequence

Ensembl Acc Id:

ENSRNOP00000027645 ⟸ ENSRNOT00000027645

RefSeq Acc Id:	XP_038967508 ⟸ XM_039111580
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038967509 ⟸ XM_039111581
- Peptide Label:	isoform X2

Protein Domains

Calpain catalytic EF-hand

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZJZ8-F1-model_v2	AlphaFold	D3ZJZ8	1-719	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-60207	BioCyc
Ensembl Genes	ENSRNOG00000020389	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027645	ENTREZGENE
	ENSRNOT00000027645.5	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.380	UniProtKB/TrEMBL
	Cysteine proteinases	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
InterPro	C2_III	UniProtKB/TrEMBL
	Calpain_cysteine_protease	UniProtKB/TrEMBL
	Calpain_domain_III	UniProtKB/TrEMBL
	Calpain_III	UniProtKB/TrEMBL
	Calpain_III_sf	UniProtKB/TrEMBL
	EF-hand-like_dom	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_Ca-bd	UniProtKB/TrEMBL
	Papain_like_cys_pep_sf	UniProtKB/TrEMBL
	Pept_cys_AS	UniProtKB/TrEMBL
	Peptidase_C2_calpain_cat	UniProtKB/TrEMBL
KEGG Report	rno:308476	UniProtKB/TrEMBL
NCBI Gene	308476	ENTREZGENE
PANTHER	CALPAIN	UniProtKB/TrEMBL
	PTHR10183:SF280	UniProtKB/TrEMBL
Pfam	Calpain_III	UniProtKB/TrEMBL
	Peptidase_C2	UniProtKB/TrEMBL
PhenoGen	Capn12	PhenoGen
PRINTS	CALPAIN	UniProtKB/TrEMBL
PROSITE	CALPAIN_CAT	UniProtKB/TrEMBL
	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	THIOL_PROTEASE_CYS	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020389	RatGTEx
SMART	calpain_III	UniProtKB/TrEMBL
	CysPc	UniProtKB/TrEMBL
Superfamily-SCOP	Peptidase_C2	UniProtKB/TrEMBL
	SSF47473	UniProtKB/TrEMBL
	SSF54001	UniProtKB/TrEMBL
UniProt	D3ZJZ8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Capn12	calpain 12	Capn12_predicted	calpain 12 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Capn12_predicted	calpain 12 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar