Ppp2r3a (protein phosphatase 2, regulatory subunit B'', alpha) - Rat Genome Database

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Gene: Ppp2r3a (protein phosphatase 2, regulatory subunit B'', alpha) Rattus norvegicus
Analyze
Symbol: Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
RGD ID: 1306958
Description: Predicted to enable protein phosphatase regulator activity and protein-macromolecule adaptor activity. Predicted to be involved in several processes, including regulation of canonical Wnt signaling pathway; regulation of cell migration involved in somitogenic axis elongation; and somitogenesis. Predicted to be part of protein phosphatase type 2A complex. Orthologous to human PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha); PARTICIPATES IN dopamine signaling pathway; mRNA decay pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA for thyroid hormone receptor binding site (258bp); LOC363122; protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88110,582,479 - 110,720,516 (-)NCBIGRCr8
mRatBN7.28101,703,512 - 101,841,530 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8101,704,778 - 101,841,502 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8107,366,598 - 107,462,469 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08105,565,916 - 105,661,788 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08103,408,435 - 103,504,306 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08109,481,352 - 109,621,462 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8109,482,614 - 109,621,408 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08108,898,749 - 109,038,840 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48106,061,334 - 106,155,090 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18106,081,385 - 106,158,939 (-)NCBI
Celera8101,095,388 - 101,189,142 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. DARPP-32, Jack of All Trades... Master of Which? Yger M and Girault JA, Front Behav Neurosci. 2011 Sep 8;5:56. doi: 10.3389/fnbeh.2011.00056. eCollection 2011.
Additional References at PubMed
PMID:15687260   PMID:16567647   PMID:17055435   PMID:34635097   PMID:34982454  


Genomics

Comparative Map Data
Ppp2r3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88110,582,479 - 110,720,516 (-)NCBIGRCr8
mRatBN7.28101,703,512 - 101,841,530 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8101,704,778 - 101,841,502 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8107,366,598 - 107,462,469 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08105,565,916 - 105,661,788 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08103,408,435 - 103,504,306 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08109,481,352 - 109,621,462 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8109,482,614 - 109,621,408 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08108,898,749 - 109,038,840 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48106,061,334 - 106,155,090 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18106,081,385 - 106,158,939 (-)NCBI
Celera8101,095,388 - 101,189,142 (-)NCBICelera
Cytogenetic Map8q31NCBI
PPP2R3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383135,965,728 - 136,147,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3135,965,728 - 136,147,894 (+)EnsemblGRCh38hg38GRCh38
GRCh373135,684,570 - 135,866,736 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363137,167,257 - 137,349,423 (+)NCBINCBI36Build 36hg18NCBI36
Build 343137,224,279 - 137,349,431NCBI
Celera3134,110,687 - 134,292,965 (+)NCBICelera
Cytogenetic Map3q22.2-q22.3NCBI
HuRef3133,061,996 - 133,244,183 (+)NCBIHuRef
CHM1_13135,647,730 - 135,830,019 (+)NCBICHM1_1
T2T-CHM13v2.03138,711,499 - 138,893,700 (+)NCBIT2T-CHM13v2.0
Ppp2r3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399100,982,188 - 101,129,031 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9100,982,283 - 101,128,994 (-)EnsemblGRCm39 Ensembl
GRCm389101,104,989 - 101,251,832 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9101,105,084 - 101,251,795 (-)EnsemblGRCm38mm10GRCm38
MGSCv379101,007,319 - 101,154,162 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369100,956,921 - 101,108,095 (-)NCBIMGSCv36mm8
Celera9100,640,744 - 100,786,778 (-)NCBICelera
Cytogenetic Map9E4NCBI
cM Map953.19NCBI
Ppp2r3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555012,648,017 - 2,752,057 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555012,648,017 - 2,751,999 (-)NCBIChiLan1.0ChiLan1.0
PPP2R3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22133,896,877 - 134,079,058 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13133,901,614 - 134,083,788 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03133,017,166 - 133,202,163 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13140,485,926 - 140,666,592 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3140,485,925 - 140,666,592 (+)Ensemblpanpan1.1panPan2
PPP2R3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12332,441,130 - 32,628,588 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2332,471,921 - 32,626,548 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2332,426,057 - 32,613,965 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02332,969,746 - 33,157,659 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2332,969,747 - 33,157,639 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12332,652,811 - 32,840,709 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02332,720,304 - 32,908,185 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02332,960,890 - 33,151,864 (+)NCBIUU_Cfam_GSD_1.0
Ppp2r3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560272,106,796 - 72,271,369 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365298,920,243 - 9,033,865 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365298,885,803 - 9,034,217 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1376,945,395 - 77,147,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11376,945,318 - 77,148,521 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21384,435,243 - 84,445,841 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11554,291,843 - 54,480,733 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604127,352,064 - 27,547,761 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473012,429,902 - 12,567,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473012,384,691 - 12,568,115 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppp2r3a
930 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:213
Count of miRNA genes:130
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000010320
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat

Markers in Region
RH142510  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,731,115 - 101,731,277 (+)MAPPERmRatBN7.2
Rnor_6.08109,508,952 - 109,509,113NCBIRnor6.0
Rnor_5.08108,926,349 - 108,926,510UniSTSRnor5.0
RGSC_v3.48106,087,689 - 106,087,850UniSTSRGSC3.4
Celera8101,121,743 - 101,121,904UniSTS
RH 3.4 Map81170.9UniSTS
Cytogenetic Map8q31UniSTS
RH142615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,705,174 - 101,705,274 (+)MAPPERmRatBN7.2
Rnor_6.08109,483,013 - 109,483,112NCBIRnor6.0
Rnor_5.08108,900,410 - 108,900,509UniSTSRnor5.0
RGSC_v3.48106,061,750 - 106,061,849UniSTSRGSC3.4
Celera8101,095,804 - 101,095,903UniSTS
RH 3.4 Map81172.7UniSTS
Cytogenetic Map8q31UniSTS
BE116212  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,734,861 - 101,735,021 (+)MAPPERmRatBN7.2
Rnor_6.08109,512,698 - 109,512,857NCBIRnor6.0
Rnor_5.08108,930,095 - 108,930,254UniSTSRnor5.0
RGSC_v3.48106,091,435 - 106,091,594UniSTSRGSC3.4
Celera8101,125,489 - 101,125,648UniSTS
RH 3.4 Map81170.0UniSTS
Cytogenetic Map8q31UniSTS
RH137441  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,704,786 - 101,704,997 (+)MAPPERmRatBN7.2
Rnor_6.08109,482,625 - 109,482,835NCBIRnor6.0
Rnor_5.08108,900,022 - 108,900,232UniSTSRnor5.0
RGSC_v3.48106,061,362 - 106,061,572UniSTSRGSC3.4
Celera8101,095,416 - 101,095,626UniSTS
Cytogenetic Map8q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 43 13 8 8 11 68 34 32 8 8
Low 1 44 41 11 41 6 1 9 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010320   ⟹   ENSRNOP00000010321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8101,704,778 - 101,798,521 (-)Ensembl
Rnor_6.0 Ensembl8109,482,614 - 109,576,353 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087334   ⟹   ENSRNOP00000069077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8101,705,359 - 101,782,914 (-)Ensembl
Rnor_6.0 Ensembl8109,483,217 - 109,560,747 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087398   ⟹   ENSRNOP00000073764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8101,722,298 - 101,841,502 (-)Ensembl
Rnor_6.0 Ensembl8109,483,855 - 109,621,408 (-)Ensembl
RefSeq Acc Id: NM_001012202   ⟹   NP_001012202
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,583,724 - 110,677,482 (-)NCBI
mRatBN7.28101,704,759 - 101,798,521 (-)NCBI
Rnor_6.08109,482,597 - 109,576,353 (-)NCBI
Rnor_5.08108,898,749 - 109,038,840 (-)NCBI
RGSC_v3.48106,061,334 - 106,155,090 (-)RGD
Celera8101,095,388 - 101,189,142 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243633   ⟹   XP_006243695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,582,479 - 110,720,516 (-)NCBI
mRatBN7.28101,704,726 - 101,841,530 (-)NCBI
Rnor_6.08109,481,352 - 109,621,462 (-)NCBI
Rnor_5.08108,898,749 - 109,038,840 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243634   ⟹   XP_006243696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,582,479 - 110,661,957 (-)NCBI
mRatBN7.28101,703,512 - 101,782,914 (-)NCBI
Rnor_6.08109,481,352 - 109,561,396 (-)NCBI
Rnor_5.08108,898,749 - 109,038,840 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001012202   ⟸   NM_001012202
- UniProtKB: D3ZLD7 (UniProtKB/TrEMBL),   A6I2G5 (UniProtKB/TrEMBL),   A0A0G2K6D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243695   ⟸   XM_006243633
- Peptide Label: isoform X1
- UniProtKB: D3ZLD7 (UniProtKB/TrEMBL),   A6I2G5 (UniProtKB/TrEMBL),   A0A0G2K6D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243696   ⟸   XM_006243634
- Peptide Label: isoform X2
- UniProtKB: Q5PQN8 (UniProtKB/TrEMBL),   A0A0G2JUF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073764   ⟸   ENSRNOT00000087398
RefSeq Acc Id: ENSRNOP00000069077   ⟸   ENSRNOT00000087334
RefSeq Acc Id: ENSRNOP00000010321   ⟸   ENSRNOT00000010320
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLD7-F1-model_v2 AlphaFold D3ZLD7 1-1150 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696222
Promoter ID:EPDNEW_R6745
Type:multiple initiation site
Name:Ppp2r3a_2
Description:protein phosphatase 2, regulatory subunit B'', alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6746  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08109,560,766 - 109,560,826EPDNEW
RGD ID:13696229
Promoter ID:EPDNEW_R6746
Type:initiation region
Name:Ppp2r3a_1
Description:protein phosphatase 2, regulatory subunit B'', alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6745  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08109,621,422 - 109,621,482EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306958 AgrOrtholog
BioCyc Gene G2FUF-29362 BioCyc
Ensembl Genes ENSRNOG00000022999 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010320 ENTREZGENE
  ENSRNOT00000010320.7 UniProtKB/TrEMBL
  ENSRNOT00000087334.2 UniProtKB/TrEMBL
  ENSRNOT00000087398.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.238.220 UniProtKB/TrEMBL
  1.10.238.230 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro EF-hand-like_dom UniProtKB/TrEMBL
  EF-hand_13 UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  P2R3A_B_D_EF-hand UniProtKB/TrEMBL
KEGG Report rno:363122 UniProtKB/TrEMBL
NCBI Gene 363122 ENTREZGENE
PANTHER PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA UniProtKB/TrEMBL
Pfam EF-hand_13 UniProtKB/TrEMBL
  EF-hand_5 UniProtKB/TrEMBL
  EF_hand_5 UniProtKB/TrEMBL
  P2R3B_EF-hand UniProtKB/TrEMBL
PhenoGen Ppp2r3a PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022999 RatGTEx
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0G2JUF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K6D1 ENTREZGENE, UniProtKB/TrEMBL
  A6I2G5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZLD7 ENTREZGENE, UniProtKB/TrEMBL
  Q5PQN8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-04-29 Ppp2r3a  protein phosphatase 2, regulatory subunit B'', alpha  Ppp2r3a  protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ppp2r3a  protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha  Ppp2r3a_predicted  protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ppp2r3a_predicted  protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha (predicted)      Symbol and Name status set to approved 70820 APPROVED