Trmt5 (tRNA methyltransferase 5) - Rat Genome Database

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Gene: Trmt5 (tRNA methyltransferase 5) Rattus norvegicus
Analyze
Symbol: Trmt5
Name: tRNA methyltransferase 5
RGD ID: 1306567
Description: Predicted to enable tRNA methyltransferase activity. Predicted to be involved in mitochondrial tRNA methylation and tRNA N1-guanine methylation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 26. Orthologous to human TRMT5 (tRNA methyltransferase 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362754; RGD1306567; similar to RIKEN cDNA 2610027O18; TRM5 tRNA methyltransferase 5 homolog; TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae); tRNA (guanine(37)-N1)-methyltransferase; tRNA (guanine-N(1)-)-methyltransferase; tRNA methyltransferase 5 homolog; tRNA methyltransferase 5 homolog (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8697,702,375 - 97,723,534 (-)NCBIGRCr8
mRatBN7.2691,963,558 - 91,987,660 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl691,943,724 - 91,987,555 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx692,370,586 - 92,377,255 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0692,670,084 - 92,676,753 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0692,097,974 - 92,104,643 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0696,164,579 - 96,171,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl696,153,014 - 96,171,779 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06105,596,366 - 105,603,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4695,708,552 - 95,715,602 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1695,712,388 - 95,719,101 (-)NCBI
Celera690,443,075 - 90,450,125 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trmt5RatBranchiootic Syndrome 3  ISORGD:13152568554872ClinVar Annotator: match by term: Branchiootic syndrome 3ClinVarPMID:25414181|PMID:28492532
Trmt5Ratcombined oxidative phosphorylation deficiency 26  ISORGD:13152568554872ClinVar Annotator: match by term: Combined oxidative phosphorylation deficiency 26 | ClinVar Annotator: match by more ...ClinVarPMID:2544623|PMID:25741868|PMID:26189817|PMID:28492532|PMID:29021354|PMID:31038196|PMID:35342985
Trmt5Ratgenetic disease  ISORGD:13152568554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trmt5Ratcombined oxidative phosphorylation deficiency 26  ISORGD:13152567240710 OMIM 

1 to 20 of 43 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trmt5Rat1,2-dichloroethane decreases expressionISORGD:16167056480464ethylene dichloride results in decreased expression of TRMT5 mRNACTDPMID:28960355
Trmt5Rat1,2-dimethylhydrazine decreases expressionISORGD:161670564804641,2-Dimethylhydrazine results in decreased expression of TRMT5 mRNACTDPMID:22206623
Trmt5Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:16167056480464Tetrachlorodibenzodioxin affects the expression of TRMT5 mRNACTDPMID:24680724
Trmt5Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of TRMT5 mRNACTDPMID:33387578
Trmt5Rat2,4-dinitrotoluene affects expressionEXP 64804642,4-dinitrotoluene affects the expression of TRMT5 mRNACTDPMID:21346803
Trmt5Rat5-aza-2'-deoxycytidine affects expressionISORGD:13152566480464Decitabine affects the expression of TRMT5 mRNACTDPMID:23300844
Trmt5Rataflatoxin B1 decreases methylationISORGD:13152566480464Aflatoxin B1 results in decreased methylation of TRMT5 geneCTDPMID:27153756
Trmt5Ratarsenous acid increases response to substanceISORGD:13152566480464TRMT5 protein results in increased susceptibility to Arsenic TrioxideCTDPMID:20707922
Trmt5Ratbis(2-chloroethyl) sulfide decreases expressionISORGD:13152566480464Mustard Gas results in decreased expression of TRMT5 mRNACTDPMID:25102026
Trmt5Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of TRMT5 mRNACTDPMID:25181051
Trmt5Ratbisphenol A increases expressionISORGD:16167056480464bisphenol A results in increased expression of TRMT5 mRNACTDPMID:29161229
Trmt5Ratcadmium dichloride decreases expressionEXP 6480464Cadmium Chloride results in decreased expression of TRMT5 mRNACTDPMID:33453195
Trmt5Ratcantharidin decreases expressionISORGD:16167056480464Cantharidin results in decreased expression of TRMT5 mRNACTDPMID:36907384
Trmt5Ratcholine multiple interactionsISORGD:16167056480464[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ...CTDPMID:20938992
Trmt5Ratcisplatin affects expressionISORGD:13152566480464Cisplatin affects the expression of TRMT5 mRNACTDPMID:23300844
Trmt5Ratcoumestrol increases expressionISORGD:13152566480464Coumestrol results in increased expression of TRMT5 mRNACTDPMID:19167446
Trmt5Ratcyclosporin A increases expressionISORGD:13152566480464Cyclosporine results in increased expression of TRMT5 mRNACTDPMID:25562108
Trmt5RatDDE increases expressionISORGD:13152566480464Dichlorodiphenyl Dichloroethylene results in increased expression of TRMT5 mRNACTDPMID:38568856
Trmt5Ratdiarsenic trioxide increases response to substanceISORGD:13152566480464TRMT5 protein results in increased susceptibility to Arsenic TrioxideCTDPMID:20707922
Trmt5RatDibutyl phosphate affects expressionISORGD:13152566480464di-n-butylphosphoric acid affects the expression of TRMT5 mRNACTDPMID:37042841

1 to 20 of 43 rows

Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trmt5Ratmethylation involved_inIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Trmt5Ratmitochondrial tRNA methylation involved_inISORGD:13152561624291 PMID:26189817RGDPMID:26189817
Trmt5Ratmitochondrial tRNA methylation involved_inIBAPANTHER:PTN000582732|SGD:S000001112|UniProtKB:Q32P411600115GO_REF:0000033GO_CentralGO_REF:0000033
Trmt5Ratmitochondrial tRNA methylation involved_inIEAUniProtKB:Q32P41|ensembl:ENSP000002612491600115GO_REF:0000107EnsemblGO_REF:0000107
Trmt5RattRNA methylation involved_inIEAUniRule:UR0001660871600115GO_REF:0000104UniProtGO_REF:0000104
Trmt5RattRNA methylation involved_inIEAARBA:ARBA000280681600115GO_REF:0000117UniProtGO_REF:0000117
Trmt5RattRNA methylation involved_inIEAInterPro:IPR0257921600115GO_REF:0000002InterProGO_REF:0000002
Trmt5RattRNA N1-guanine methylation involved_inIBAPANTHER:PTN000582806|SGD:S000001112|TAIR:locus:20783861600115GO_REF:0000033GO_CentralGO_REF:0000033
Trmt5RattRNA processing involved_inIEAUniProtKB-KW:KW-08191600115GO_REF:0000043UniProtGO_REF:0000043
1 to 9 of 9 rows

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trmt5Ratcytoplasm located_inIEAUniRule:UR0001660871600115GO_REF:0000104UniProtGO_REF:0000104
Trmt5Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Trmt5Ratcytoplasm is_active_inIBAPANTHER:PTN000582729|SGD:S000001112|UniProtKB:Q32P41|UniProtKB:Q57X101600115GO_REF:0000033GO_CentralGO_REF:0000033
Trmt5Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Trmt5Ratmitochondrial matrix located_inISORGD:13152561624291 PMID:26189817RGDPMID:26189817
Trmt5Ratmitochondrial matrix located_inIEAUniProtKB-SubCell:SL-01701600115GO_REF:0000044UniProtGO_REF:0000044
Trmt5Ratmitochondrial matrix is_active_inIBAPANTHER:PTN000582732|SGD:S000001112|UniProtKB:Q32P411600115GO_REF:0000033GO_CentralGO_REF:0000033
Trmt5Ratmitochondrial matrix located_inIEAUniProtKB:Q32P41|ensembl:ENSP000002612491600115GO_REF:0000107EnsemblGO_REF:0000107
Trmt5Ratmitochondrial matrix located_inIEAUniRule:UR0001660871600115GO_REF:0000104UniProtGO_REF:0000104
Trmt5Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Trmt5Ratnucleus located_inIEAUniRule:UR0001660871600115GO_REF:0000104UniProtGO_REF:0000104
Trmt5Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Trmt5Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
1 to 13 of 13 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Trmt5Ratmethyltransferase activity enablesIEAUniProtKB-KW:KW-04891600115GO_REF:0000043UniProtGO_REF:0000043
Trmt5Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Trmt5RattRNA (guanine(37)-N1)-methyltransferase activity enablesIEAEC:2.1.1.2281600115GO_REF:0000003UniProtGO_REF:0000003
Trmt5RattRNA (guanine(37)-N1)-methyltransferase activity enablesIEAUniRule:UR0001660871600115GO_REF:0000104UniProtGO_REF:0000104
Trmt5RattRNA (guanine(37)-N1)-methyltransferase activity enablesIEAInterPro:IPR0257921600115GO_REF:0000002InterProGO_REF:0000002
Trmt5RattRNA (guanine(37)-N1)-methyltransferase activity enablesIEARHEA:368991600115GO_REF:0000116RHEAGO_REF:0000116
Trmt5RattRNA methyltransferase activity enablesIBAPANTHER:PTN000582729|SGD:S000001112|SGD:S000003018|TAIR:locus:2078386|UniProtKB:Q582931600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:26189817   PMID:34800366  



Trmt5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8697,702,375 - 97,723,534 (-)NCBIGRCr8
mRatBN7.2691,963,558 - 91,987,660 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl691,943,724 - 91,987,555 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx692,370,586 - 92,377,255 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0692,670,084 - 92,676,753 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0692,097,974 - 92,104,643 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0696,164,579 - 96,171,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl696,153,014 - 96,171,779 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06105,596,366 - 105,603,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4695,708,552 - 95,715,602 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1695,712,388 - 95,719,101 (-)NCBI
Celera690,443,075 - 90,450,125 (-)NCBICelera
Cytogenetic Map6q24NCBI
TRMT5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381460,971,441 - 60,981,690 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1460,971,441 - 60,981,170 (-)EnsemblGRCh38hg38GRCh38
GRCh371461,438,159 - 61,448,408 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361460,507,912 - 60,517,535 (-)NCBINCBI36Build 36hg18NCBI36
Celera1441,488,423 - 41,498,046 (-)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1441,601,518 - 41,611,139 (-)NCBIHuRef
CHM1_11461,377,442 - 61,387,063 (-)NCBICHM1_1
T2T-CHM13v2.01455,177,981 - 55,188,230 (-)NCBIT2T-CHM13v2.0
Trmt5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391273,315,289 - 73,333,754 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1273,326,785 - 73,333,484 (-)EnsemblGRCm39 Ensembl
GRCm381273,268,515 - 73,286,975 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1273,280,011 - 73,286,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv371274,381,397 - 74,387,698 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361274,198,849 - 74,205,538 (-)NCBIMGSCv36mm8
Celera1274,391,725 - 74,398,044 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1230.42NCBI
Trmt5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554668,680,429 - 8,685,942 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554668,679,795 - 8,690,203 (+)NCBIChiLan1.0ChiLan1.0
TRMT5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21562,108,241 - 62,118,481 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11461,328,331 - 61,334,686 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01441,578,241 - 41,588,494 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11459,836,893 - 59,847,145 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1459,836,906 - 59,845,936 (-)Ensemblpanpan1.1panPan2
TRMT5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1835,952,183 - 35,960,681 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl835,952,365 - 35,960,945 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha835,705,590 - 35,714,105 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0836,185,634 - 36,194,515 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl836,183,069 - 36,194,043 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1835,796,181 - 35,805,034 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0835,873,622 - 35,882,503 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0836,235,460 - 36,244,350 (-)NCBIUU_Cfam_GSD_1.0
Trmt5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864069,053,660 - 69,063,587 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364955,127,113 - 5,138,343 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364955,131,642 - 5,137,998 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1189,909,660 - 189,923,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11189,909,654 - 189,923,308 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21211,196,389 - 211,205,568 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRMT5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12438,164,262 - 38,173,917 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2438,167,915 - 38,174,140 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605326,418,791 - 26,428,466 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trmt5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473440,144,291 - 40,149,362 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473440,143,073 - 40,154,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Trmt5
85 total Variants


Assembly: mRatBN7.2
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
6 91981681 91981682 G A snv ACI/EurMcwi (2019), RCS/LavRrrcMcwi (2021), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), M520/NRrrcMcwi (2019), M520/N (2020), MWF/Hsd (2019), PVG/Seac (2019), ACI/EurMcwi (2019NG), BDIX/NemOdaMcwi (2022), BUF/MnaMcwi (2022), DA/OlaHsd (2019NG), F344/DuCrl (2019NG), F344/DuCrl (2019NG), F344/DuCrl (2021), European Variation Archive Release 3, European Variation Archive Release 4, LEXF2A/StmMcwi (2023), FXLE26/StmMcwi (2023), FXLE22/StmMcwi (2023), FXLE20/StmMcwi (2023), LEXF8D/StmMcwi (2023), LEXF6B/StmMcwi (2023), FXLE15/StmMcwi (2023), FXLE21/StmMcwi (2023), LEXF5/StmMcwi (2023), FXLE12/StmMcwi (2023), European Variation Archive Release 6, F344/NHsd (2021), F344/StmMcwi (2019), FHH/EurMcwi (2019NG), FXLE12/StmMcwi (2021), FXLE12/Stm (2019NG), FXLE15/StmMcwi (2021), FXLE15/Stm (2019NG), FXLE19/StmMcwi (2022), FXLE20/Stm (2019NG), FXLE23/Stm (2022), FXLE26/Stm (2022), LEW/Crl (2019NG), LEXF1C/StmMcwi (2021), LEXF2A/Stm (2022), LEXF2C/StmMcwi (2022), LEXF5/Stm (2019NG), LEXF6B/Stm (2019NG), LEXF8A/StmMcwi (2021), LEXF8D/Stm (2022), LEXF9/StmMcwi (2022), M520/NRrrcMcwi (2019NG), MWF/SimwMcwi (2019NG), MWF/SimwMcwi (2019), ACI/N (2020) View more Information

Predicted Target Of
Summary Value
Count of predictions:319
Count of miRNA genes:196
Interacting mature miRNAs:223
Transcripts:ENSRNOT00000010546
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat

1 to 10 of 29 rows
RH133482  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8697,716,885 - 97,717,448 (+)Marker Load Pipeline
mRatBN7.2691,981,031 - 91,981,594 (+)MAPPERmRatBN7.2
Rnor_6.0696,165,116 - 96,165,678NCBIRnor6.0
Rnor_5.06105,596,903 - 105,597,465UniSTSRnor5.0
RGSC_v3.4695,709,088 - 95,709,650UniSTSRGSC3.4
Celera690,443,612 - 90,444,174UniSTS
RH 3.4 Map6660.2UniSTS
Cytogenetic Map6q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000010546   ⟹   ENSRNOP00000010546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl691,980,495 - 91,986,042 (-)Ensembl
Rnor_6.0 Ensembl696,164,579 - 96,171,629 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078190   ⟹   ENSRNOP00000068961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl691,943,724 - 91,987,555 (-)Ensembl
Rnor_6.0 Ensembl696,153,014 - 96,171,779 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113633   ⟹   ENSRNOP00000079268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl691,943,724 - 91,986,360 (-)Ensembl
RefSeq Acc Id: NM_001396073   ⟹   NP_001383002
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8697,716,731 - 97,723,399 (-)NCBI
mRatBN7.2691,980,877 - 91,987,545 (-)NCBI
RefSeq Acc Id: NM_001396074   ⟹   NP_001383003
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8697,716,731 - 97,723,399 (-)NCBI
mRatBN7.2691,980,877 - 91,987,545 (-)NCBI
RefSeq Acc Id: XM_039112507   ⟹   XP_038968435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8697,702,375 - 97,723,534 (-)NCBI
mRatBN7.2691,963,558 - 91,987,660 (-)NCBI
RefSeq Acc Id: XM_039112509   ⟹   XP_038968437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8697,716,731 - 97,723,534 (-)NCBI
mRatBN7.2691,980,877 - 91,987,660 (-)NCBI
1 to 11 of 11 rows
Protein RefSeqs NP_001383002 (Get FASTA)   NCBI Sequence Viewer  
  NP_001383003 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968435 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968437 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03610 (Get FASTA)   NCBI Sequence Viewer  
  EDM03611 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010546
  ENSRNOP00000010546.6
  ENSRNOP00000068961
  ENSRNOP00000068961.1
  ENSRNOP00000079268.1
1 to 11 of 11 rows
Ensembl Acc Id: ENSRNOP00000068961   ⟸   ENSRNOT00000078190
Ensembl Acc Id: ENSRNOP00000010546   ⟸   ENSRNOT00000010546
RefSeq Acc Id: XP_038968435   ⟸   XM_039112507
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JU45 (UniProtKB/TrEMBL),   A0A8I5ZMD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968437   ⟸   XM_039112509
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000079268   ⟸   ENSRNOT00000113633
SAM-dependent methyltransferase TRM5/TYW2-type

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JU45-F1-model_v2 AlphaFold A0A0G2JU45 1-496 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694664
Promoter ID:EPDNEW_R5188
Type:initiation region
Name:Trmt5_1
Description:tRNA methyltransferase 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0696,171,635 - 96,171,695EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-37114 BioCyc
BioCyc Pathway PWY-6829 [tRNA methylation (yeast)] BioCyc
  PWY-7286 [7-(3-amino-3-carboxypropyl)-wyosine biosynthesis] BioCyc
BioCyc Pathway Image PWY-6829 BioCyc
  PWY-7286 BioCyc
Ensembl Genes ENSRNOG00000007785 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010546 ENTREZGENE
  ENSRNOT00000010546.8 UniProtKB/TrEMBL
  ENSRNOT00000078190 ENTREZGENE
  ENSRNOT00000078190.2 UniProtKB/TrEMBL
  ENSRNOT00000113633.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
  Met-10+ protein-like domains UniProtKB/TrEMBL
InterPro MeTrfase_TRM5/TYW2 UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
  tRNA_Gua_MeTrfase_euk UniProtKB/TrEMBL
NCBI Gene 362754 ENTREZGENE
PANTHER TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE UniProtKB/TrEMBL
  TRNA METHYLTRANSFERASE UniProtKB/TrEMBL
Pfam Met_10 UniProtKB/TrEMBL
PhenoGen Trmt5 PhenoGen
PROSITE SAM_MT_TRM5_TYW2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007785 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0G2JU45 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMD1 ENTREZGENE, UniProtKB/TrEMBL
  A6HC55 ENTREZGENE, UniProtKB/TrEMBL
  A6HC56 ENTREZGENE, UniProtKB/TrEMBL
  F1LYK6 ENTREZGENE, UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-02 Trmt5  tRNA methyltransferase 5  Trmt5  tRNA methyltransferase 5 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-17 Trmt5  tRNA methyltransferase 5 homolog (S. cerevisiae)  Trmt5  TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Trmt5  TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)   Trmt5_predicted  TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Trmt5_predicted  TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) (predicted)  RGD1306567_predicted  similar to RIKEN cDNA 2610027O18 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1306567_predicted  similar to RIKEN cDNA 2610027O18 (predicted)  LOC362754_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362754_predicted  similar to RIKEN cDNA 2610027O18 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL