Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Aqr | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | AQR (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AQR mRNA | CTD | PMID:22079256 | Aqr | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Aqr (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of AQR mRNA | CTD | PMID:22206623 | Aqr | Rat | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | AQR (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to AQR protein | CTD | PMID:32991956 | Aqr | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | AQR (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Aqr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Aqr (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AQR mRNA | CTD | PMID:19465110 | Aqr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AQR mRNA | CTD | PMID:34747641 | Aqr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Aqr (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of AQR mRNA | CTD | PMID:21570461 | Aqr | Rat | 2,4,6-tribromophenol | increases expression | ISO | AQR (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Aqr | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of AQR mRNA | CTD | PMID:30851411 | Aqr | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | AQR (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of AQR protein | CTD | PMID:31675489 | Aqr | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of AQR mRNA | CTD | PMID:30047161 | Aqr | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of AQR mRNA | CTD | PMID:30047161 | Aqr | Rat | antirheumatic drug | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of AQR mRNA | CTD | PMID:24449571 | Aqr | Rat | aristolochic acid A | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of AQR mRNA | CTD | PMID:33212167 | Aqr | Rat | arsane | affects methylation | ISO | AQR (Homo sapiens) | 6480464 | Arsenic affects the methylation of AQR gene | CTD | PMID:25304211 | Aqr | Rat | arsenic atom | affects methylation | ISO | AQR (Homo sapiens) | 6480464 | Arsenic affects the methylation of AQR gene | CTD | PMID:25304211 | Aqr | Rat | arsenite(3-) | multiple interactions | ISO | AQR (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to AQR mRNA] | CTD | PMID:32406909 | Aqr | Rat | benzo[a]pyrene | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of AQR mRNA | CTD | PMID:20064835 | Aqr | Rat | benzo[a]pyrene | increases expression | ISO | Aqr (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of AQR mRNA | CTD | PMID:22228805 | Aqr | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Aqr | Rat | benzo[a]pyrene diol epoxide I | affects expression | ISO | AQR (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Aqr | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of AQR mRNA | CTD | PMID:25181051 more ... | Aqr | Rat | bisphenol A | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of AQR protein | CTD | PMID:31675489 | Aqr | Rat | bisphenol A | decreases methylation | ISO | AQR (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of AQR gene | CTD | PMID:31601247 | Aqr | Rat | bisphenol A | decreases methylation | ISO | Aqr (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of AQR promoter | CTD | PMID:27312807 | Aqr | Rat | carbamazepine | affects expression | ISO | AQR (Homo sapiens) | 6480464 | Carbamazepine affects the expression of AQR mRNA | CTD | PMID:24752500 | Aqr | Rat | chlorpyrifos | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of AQR mRNA | CTD | PMID:37019170 | Aqr | Rat | cisplatin | multiple interactions | ISO | Aqr (Mus musculus) | 6480464 | [Cisplatin co-treated with Lutein] results in decreased expression of AQR mRNA | CTD | PMID:24865317 | Aqr | Rat | cisplatin | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | Cisplatin results in decreased expression of AQR mRNA | CTD | PMID:24865317 | Aqr | Rat | cypermethrin | increases expression | ISO | Aqr (Mus musculus) | 6480464 | cypermethrin results in increased expression of AQR mRNA | CTD | PMID:21142847 | Aqr | Rat | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of AQR mRNA | CTD | PMID:23640034 | Aqr | Rat | diclofenac | affects expression | ISO | AQR (Homo sapiens) | 6480464 | Diclofenac affects the expression of AQR mRNA | CTD | PMID:24752500 | Aqr | Rat | doxorubicin | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of AQR mRNA | CTD | PMID:29803840 | Aqr | Rat | enzyme inhibitor | multiple interactions | ISO | AQR (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of AQR protein | CTD | PMID:23301498 | Aqr | Rat | folic acid | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | Folic Acid results in decreased expression of AQR mRNA | CTD | PMID:25629700 | Aqr | Rat | FR900359 | decreases phosphorylation | ISO | AQR (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of AQR protein | CTD | PMID:37730182 | Aqr | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of AQR mRNA | CTD | PMID:22061828 | Aqr | Rat | ivermectin | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of AQR protein | CTD | PMID:32959892 | Aqr | Rat | lead(0) | affects expression | ISO | AQR (Homo sapiens) | 6480464 | Lead affects the expression of AQR mRNA | CTD | PMID:28903495 | Aqr | Rat | lutein | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | Lutein results in decreased expression of AQR mRNA | CTD | PMID:24865317 | Aqr | Rat | lutein | multiple interactions | ISO | Aqr (Mus musculus) | 6480464 | [Cisplatin co-treated with Lutein] results in decreased expression of AQR mRNA | CTD | PMID:24865317 | Aqr | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of AQR mRNA | CTD | PMID:30047161 | Aqr | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of AQR mRNA | CTD | PMID:25729387 | Aqr | Rat | paracetamol | increases expression | ISO | AQR (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of AQR mRNA | CTD | PMID:22230336 | Aqr | Rat | paraquat | multiple interactions | ISO | Aqr (Mus musculus) | 6480464 | APOD protein affects the reaction [Paraquat results in decreased expression of AQR mRNA] | CTD | PMID:21688324 | Aqr | Rat | paraquat | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | Paraquat results in decreased expression of AQR mRNA | CTD | PMID:21688324 | Aqr | Rat | pirinixic acid | increases expression | ISO | Aqr (Mus musculus) | 6480464 | pirinixic acid results in increased expression of AQR mRNA | CTD | PMID:23811191 | Aqr | Rat | potassium chromate | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of AQR mRNA | CTD | PMID:22079256 | Aqr | Rat | potassium chromate | multiple interactions | ISO | AQR (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AQR mRNA | CTD | PMID:22079256 | Aqr | Rat | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of AQR mRNA | CTD | PMID:30047161 | Aqr | Rat | rac-lactic acid | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of AQR mRNA | CTD | PMID:30851411 | Aqr | Rat | resveratrol | multiple interactions | ISO | AQR (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of AQR mRNA | CTD | PMID:23557933 | Aqr | Rat | silicon dioxide | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of AQR mRNA | CTD | PMID:19073995 | Aqr | Rat | silver atom | increases expression | ISO | Aqr (Mus musculus) | 6480464 | Silver results in increased expression of AQR mRNA | CTD | PMID:19429238 | Aqr | Rat | silver(0) | increases expression | ISO | Aqr (Mus musculus) | 6480464 | Silver results in increased expression of AQR mRNA | CTD | PMID:19429238 | Aqr | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of AQR mRNA | CTD | PMID:30047161 | Aqr | Rat | tert-butyl hydroperoxide | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of AQR mRNA | CTD | PMID:15336504 | Aqr | Rat | thapsigargin | increases expression | ISO | Aqr (Mus musculus) | 6480464 | Thapsigargin results in increased expression of AQR protein | CTD | PMID:24648495 | Aqr | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of AQR mRNA | CTD | PMID:34492290 | Aqr | Rat | titanium dioxide | decreases expression | ISO | Aqr (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of AQR mRNA | CTD | PMID:29264374 | Aqr | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of AQR mRNA | CTD | PMID:25729387 | Aqr | Rat | triptonide | increases expression | ISO | Aqr (Mus musculus) | 6480464 | triptonide results in increased expression of AQR mRNA | CTD | PMID:33045310 | Aqr | Rat | valproic acid | affects expression | ISO | Aqr (Mus musculus) | 6480464 | Valproic Acid affects the expression of AQR mRNA | CTD | PMID:17963808 | Aqr | Rat | valproic acid | affects expression | ISO | AQR (Homo sapiens) | 6480464 | Valproic Acid affects the expression of AQR mRNA | CTD | PMID:25979313 | Aqr | Rat | valproic acid | decreases expression | ISO | AQR (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of AQR mRNA | CTD | PMID:23179753 and PMID:27188386 | |