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Gene: PRSS47P (serine protease 47, pseudogene) Homo sapiens

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Symbol:

PRSS47P

Name:

serine protease 47, pseudogene

RGD ID:

9586643

HGNC Page

HGNC:37326

Description:

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space.

Type:

pseudo (Ensembl: transcribed_unprocessed_pseudogene)

RefSeq Status:

INFERRED

Previously known as:

protease, serine 47; protease, serine, 47; PRSS47; putative serine protease 47; serine protease 47

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	92,177,163 - 92,191,156 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	92,177,235 - 92,189,635 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	94,939,445 - 94,953,438 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	93,979,266 - 93,992,679 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	65,375,741 - 65,389,155 (-)	NCBI		Celera
Cytogenetic Map	9	q22.31	NCBI
HuRef	9	64,617,377 - 64,630,720 (-)	NCBI		HuRef
T2T-CHM13v2.0	9	104,343,670 - 104,357,663 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary sensory and autonomic neuropathy type 1 (IAGP)

hereditary sensory neuropathy (IAGP)

spinal muscular atrophy with lower extremity predominant 2A (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

6-propyl-2-thiouracil (ISO)

amitrole (ISO)

methimazole (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

sulfadimethoxine (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis (IBA,IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IBA)

Molecular Function

serine-type endopeptidase activity (IBA,IEA)

serine-type peptidase activity (IEA)

References

Additional References at PubMed

PMID:21873635

Genomics

Comparative Map Data

PRSS47P
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	92,177,163 - 92,191,156 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	92,177,235 - 92,189,635 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	94,939,445 - 94,953,438 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	93,979,266 - 93,992,679 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	65,375,741 - 65,389,155 (-)	NCBI		Celera
Cytogenetic Map	9	q22.31	NCBI
HuRef	9	64,617,377 - 64,630,720 (-)	NCBI		HuRef
T2T-CHM13v2.0	9	104,343,670 - 104,357,663 (-)	NCBI		T2T-CHM13v2.0

Prss47
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	65,192,427 - 65,200,685 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	65,192,420 - 65,200,574 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	65,044,613 - 65,052,871 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	65,044,606 - 65,052,760 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	65,146,086 - 65,154,068 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	65,059,569 - 65,067,551 (-)	NCBI		MGSCv36	mm8
Celera	13	66,681,436 - 66,689,362 (-)	NCBI		Celera
Cytogenetic Map	13	B3	NCBI
cM Map	13	34.21	NCBI

Prss47
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	145,606 - 160,046 (+)	NCBI		GRCr8
mRatBN7.2	17	139,835 - 154,263 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	140,603 - 154,261 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	17	2,814,264 - 2,828,350 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	2,814,431 - 2,827,001 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	5,046,191 - 5,059,896 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	5,612,357 - 5,626,529 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	2,354,796 - 2,368,873 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

PRSS47P
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	47,305,930 - 47,319,863 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	47,308,316 - 47,322,249 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	63,241,482 - 63,246,209 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

LOC476356
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	97,734,075 - 97,742,179 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	100,667,843 - 100,675,953 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	98,347,778 - 98,356,028 (+)	NCBI		ROS_Cfam_1.0
UNSW_CanFamBas_1.0	1	97,692,811 - 97,701,058 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	98,451,710 - 98,459,960 (-)	NCBI		UU_Cfam_GSD_1.0

LOC110259104
(Sus scrofa - pig)

No map positions available.

PRSS47
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	102,720,299 - 102,736,257 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	90,990,149 - 91,014,263 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 9p24.3-q34.3(chr9:204193-138179445)	copy number gain	See cases [RCV000133791]	Chr9:204193..138179445 [GRCh38] Chr9:204193..141073897 [GRCh37] Chr9:194193..140193718 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9q21.11-31.2(chr9:68420430-106579493)x3	copy number gain	See cases [RCV000136788]	Chr9:68420430..106579493 [GRCh38] Chr9:71130848..109341774 [GRCh37] Chr9:70225166..108381595 [NCBI36] Chr9:9q21.11-31.2	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124524)x3	copy number gain	See cases [RCV000138783]	Chr9:193412..138124524 [GRCh38] Chr9:204090..141018976 [GRCh37] Chr9:194090..140138797 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9p11.2-q34.3(chr9:193412-138159073)x3	copy number gain	See cases [RCV000139207]	Chr9:193412..138159073 [GRCh38] Chr9:68420641..141053525 [GRCh37] Chr9:67910461..140173346 [NCBI36] Chr9:9p11.2-q34.3	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138159073)x3	copy number gain	See cases [RCV000138962]	Chr9:193412..138159073 [GRCh38] Chr9:204104..141053525 [GRCh37] Chr9:194104..140173346 [NCBI36] Chr9:9p24.3-q34.3	pathogenic\|conflicting data from submitters
GRCh38/hg38 9q21.12-31.3(chr9:69627642-111454304)x3	copy number gain	See cases [RCV000139789]	Chr9:69627642..111454304 [GRCh38] Chr9:72242558..114216584 [GRCh37] Chr9:71432378..113256405 [NCBI36] Chr9:9q21.12-31.3	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:203861-138125937)x3	copy number gain	See cases [RCV000141876]	Chr9:203861..138125937 [GRCh38] Chr9:203861..141020389 [GRCh37] Chr9:193861..140140210 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9q22.31(chr9:92094765-92337566)x3	copy number gain	See cases [RCV000143043]	Chr9:92094765..92337566 [GRCh38] Chr9:94857047..95099848 [GRCh37] Chr9:93896868..94139669 [NCBI36] Chr9:9q22.31	uncertain significance
GRCh38/hg38 9p24.3-q34.3(chr9:203862-138125937)x3	copy number gain	See cases [RCV000143476]	Chr9:203862..138125937 [GRCh38] Chr9:203862..141020389 [GRCh37] Chr9:193862..140140210 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3	copy number gain	See cases [RCV000148113]	Chr9:193412..138179445 [GRCh38] Chr9:204193..141073897 [GRCh37] Chr9:194193..140193718 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3	copy number gain	See cases [RCV000050348]	Chr9:193412..138179445 [GRCh38] Chr9:204193..141073897 [GRCh37] Chr9:194193..140193718 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9q22.31(chr9:91935027-92331095)x3	copy number gain	See cases [RCV000052234]	Chr9:91935027..92331095 [GRCh38] Chr9:94697309..95093377 [GRCh37] Chr9:93737130..94133198 [NCBI36] Chr9:9q22.31	uncertain significance
GRCh38/hg38 9q22.31-22.33(chr9:91596533-97018746)x1	copy number loss	See cases [RCV000052916]	Chr9:91596533..97018746 [GRCh38] Chr9:94358815..99781028 [GRCh37] Chr9:93398636..98820849 [NCBI36] Chr9:9q22.31-22.33	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124532)x3	copy number gain	See cases [RCV000053745]	Chr9:193412..138124532 [GRCh38] Chr9:204193..141018984 [GRCh37] Chr9:194193..140138805 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]\|See cases [RCV000053748]	Chr9:193412..138179445 [GRCh38] Chr9:266045..141073897 [GRCh37] Chr9:256045..140193718 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh38/hg38 9q22.1-32(chr9:88522292-113687796)x3	copy number gain	See cases [RCV000053752]	Chr9:88522292..113687796 [GRCh38] Chr9:91137207..116450076 [GRCh37] Chr9:90327027..115489897 [NCBI36] Chr9:9q22.1-32	pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138114463)x3	copy number gain	See cases [RCV000053746]	Chr9:193412..138114463 [GRCh38] Chr9:214367..141008915 [GRCh37] Chr9:204367..140128736 [NCBI36] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:163131-141122114)x3	copy number gain	See cases [RCV000240081]	Chr9:163131..141122114 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:62525-141006407)	copy number gain	See cases [RCV000449375]	Chr9:62525..141006407 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020389)x3	copy number gain	not specified [RCV003986800]	Chr9:203861..141020389 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203864-141020389)x3	copy number gain	See cases [RCV000448978]	Chr9:203864..141020389 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9q21.11-34.3(chr9:71069743-140999928)	copy number gain	Global developmental delay [RCV000626548]	Chr9:71069743..140999928 [GRCh37] Chr9:9q21.11-34.3	likely pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203862-141020389)	copy number gain	See cases [RCV000512392]	Chr9:203862..141020389 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9q22.31(chr9:94907633-96493970)x1	copy number loss	not provided [RCV000683156]	Chr9:94907633..96493970 [GRCh37] Chr9:9q22.31	uncertain significance
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141122247)x3	copy number gain	not provided [RCV000748055]	Chr9:10590..141122247 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141107672)x3	copy number gain	not provided [RCV000748053]	Chr9:10590..141107672 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:46587-141066491)x3	copy number gain	not provided [RCV000748063]	Chr9:46587..141066491 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141114095)x2	copy number gain	not provided [RCV000748054]	Chr9:10590..141114095 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020388)x3	copy number gain	not provided [RCV000845900]	Chr9:203861..141020388 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9q21.2-22.32(chr9:79520825-97201274)	copy number gain	not provided [RCV000767645]	Chr9:79520825..97201274 [GRCh37] Chr9:9q21.2-22.32	pathogenic
GRCh37/hg19 9q22.31(chr9:94667669-95345847)x3	copy number gain	not provided [RCV000847811]	Chr9:94667669..95345847 [GRCh37] Chr9:9q22.31	uncertain significance
GRCh37/hg19 9q21.11-34.3(chr9:71416475-141020389)x3	copy number gain	not provided [RCV000847808]	Chr9:71416475..141020389 [GRCh37] Chr9:9q21.11-34.3	pathogenic
GRCh37/hg19 9q22.31(chr9:94671200-95325631)x3	copy number gain	See cases [RCV001007416]	Chr9:94671200..95325631 [GRCh37] Chr9:9q22.31	uncertain significance
NC_000009.11:g.12246100_101559378inv	inversion	Recurrent spontaneous abortion [RCV000999471]	Chr9:12246100..101559378 [GRCh37] Chr9:9p23-q22.33	likely pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:353349-141020389)	copy number gain	not specified [RCV002053823]	Chr9:353349..141020389 [GRCh37] Chr9:9p24.3-q34.3	pathogenic
GRCh37/hg19 9q21.11-33.2(chr9:71349994-122603410)	copy number gain	not specified [RCV002053853]	Chr9:71349994..122603410 [GRCh37] Chr9:9q21.11-33.2	likely pathogenic
NC_000009.11:g.(?_94794747)_(95527026_?)del	deletion	Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures [RCV001900344]\|Hereditary sensory and autonomic neuropathy type 1 [RCV001875146]	Chr9:94794747..95527026 [GRCh37] Chr9:9q22.31	uncertain significance
NC_000009.11:g.(?_94485944)_(95527026_?)del	deletion	not provided [RCV003113522]	Chr9:94485944..95527026 [GRCh37] Chr9:9q22.31	pathogenic
GRCh37/hg19 9q22.2-31.1(chr9:93864974-106661581)x1	copy number loss	Gorlin syndrome [RCV002279743]	Chr9:93864974..106661581 [GRCh37] Chr9:9q22.2-31.1	pathogenic
GRCh37/hg19 9p24.3-q34.11(chr9:203861-131603223)x3	copy number gain	See cases [RCV002292402]	Chr9:203861..131603223 [GRCh37] Chr9:9p24.3-q34.11	pathogenic
GRCh37/hg19 9p22.1-q33.1(chr9:19356861-119513311)	copy number loss	Distal tetrasomy 15q [RCV002280776]	Chr9:19356861..119513311 [GRCh37] Chr9:9p22.1-q33.1	uncertain significance
GRCh37/hg19 9q22.31(chr9:94666958-95339157)x3	copy number gain	not provided [RCV002475857]	Chr9:94666958..95339157 [GRCh37] Chr9:9q22.31	uncertain significance
Single allele	deletion	not provided [RCV003448676]	Chr9:92679543..109378847 [GRCh37] Chr9:9q22.2-31.2	pathogenic
GRCh37/hg19 9q22.31(chr9:94666957-95345707)x3	copy number gain	not specified [RCV003986810]	Chr9:94666957..95345707 [GRCh37] Chr9:9q22.31	uncertain significance
GRCh37/hg19 9q22.2-22.31(chr9:92891639-95599825)x3	copy number gain	not provided [RCV004819549]	Chr9:92891639..95599825 [GRCh37] Chr9:9q22.2-22.31	uncertain significance

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system
54	77	214	96	295	49	127	16	84	13	94	286	291	6	358	41	229	104	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_076102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001350291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AL136097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HY036024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HY221149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000611097

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	9	92,177,235 - 92,189,635 (-)	Ensembl

Ensembl Acc Id:

ENST00000672321

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	9	92,186,950 - 92,191,156 (-)	Ensembl

RefSeq Acc Id:

NM_001350291 ⟹ NP_001337220

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	9	92,184,332 - 92,191,156 (-)	NCBI

Sequence:

show sequence

AAAGGGGATGCATGGGAGACCTTGCGGATGTAGGAACTGCTCCTTTTGTTGCTGGAGTGGTGGA
TGGGAGACTCTACACATTGGCTCAGATCCATGGAACTGCACAGCCCTGAGACTGAACTTTCGTG
TGTGCAAACTAAAAAAATCAACCAGGATGGAAATAAAAACTCATCAAACGTATACATGGGATAC
TTACATTTCATTCCAGGTGGCTCCAGAGACGACATCAAGCAAGTGTGTGGGAAGCCTAAGGTGG
TGGGGAAGATCTATGGTGGCCGGGACGCAGCAGCTGGCCAGTGGCCATGGCAGGCCAGCCTGCT
CTACTGGGGCTCGCACCTCTGTGGAGCTGTCCTCATCGACTCCTGCTGGCTGGTATCAACTACC
CACTGCTTTCTCAACAAATCCCAGGCCCCGAAGAACTATCAGGTTCTGTTGGGAAACATCCAAC
TGTATCATCAAACCCAGCACACCCAGAAGATGTCTGTGCACCGGATCATCACCCATCCAGACTT
TGAGAAGCTCCACCCCTTTGGGAGTGACATTGCCATGTTGCAGCTGCACCTGCCTATGAACTTC
ACTTCCTACATTGTCCCTGTCTGCCTCCCATCCCGGGACATGCAGCTGCCCAGTAACGTGTCCT
GTTGGATAACCGGCTGGGGAATGCTCACCGAAGACCATAAGAGGGGTGTGGGAGAGGCGGGAGG
ATGAGGGAGGGGAAGGAGAGGGAGGCAGAGGGGAAGAAGGAAGGATGGCTTAGCCAGGCAAAGA
GGAAGCCACTGGACTTGGCCCTCTGTGCCTCATTTCCATGACCGGTAAGGTGAGGACCACCACG
CTGGGGCCTTTCTACTTCTGAAAGTTTGTGATCCCATAGCTTTAGAGTTCCCTGAGTCCCAGGC
TCTGAAAGTCTGGGAATCTTTAACTTTTGAGAATCCAGAATCTGGGTTCTTTGAGTCTTCATGG
TTCTTCTTTTTAATGTTTTATTTATTTATTCATTTATTTATTTACTTATTTATTTTTTGAGACG
GAGTCTCACTCTGTCACCTAGGCTAGAGTACAGTGGCATGATCTCGGCTCACTGCAACCTCCGC
CTCCCAGGTTCAAGCAATTCTCCTGCCTTAGCCTCTCAAGTAGCTGGCATTACAGGCATGCACC
ACCATGCCCGGCTAATTTTGTATCTTTAGTAGAGACAGGGTTTCTCCATGTAGGTCAGGCTGGT
CTTGAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGCTTCCCAAAGTGCTGGGATGACAGGCG
TGAGCCACTATTTTAAGGTTTTAGTCAGCCATGGGACTAAGATGACTCGATTGAACTCCAAAGA
CATGCTTGGGGGCTGGCCCATTCTAGGTCACCACCAAACACTTGGATCGTCCCTTGCTTGGGAA
GGTGCTTGGGAAGAGTGGAGAGAAAACACATGGTGGCTCTGCAGTCTGAGGCTGCATGATCCAG
TTAGAATGATTGCGACGTAGAACTCTTGACCTTCTCTGAACCTCATGTTGCTCTTATCCTAACC
TGGGTCATTCATCTACTTCACAGTCTTGTTACGTGACTGAATAACAGAGGAGAGAGTTGTGTGT
GTTTTCATCGTTAGATGAGTAGGAAAGAAATGTAAGCAAAGATTTATACACAAGAGTGTTTATT
GAAGAAAGGAGTGTTTACAGTTTAGGGAAATGCTTATGGTATGATGTTAAGGGAAAAAGGAAGA
ACATATATTTAATTATGTGTAGGGTTAGCATTTCTCAACAGAGGTGCTGTACGTATTTTTGATA
GAATATGTCTTCACTGAGTGGGGCTCTGCTAGCATCCATGGCCTTTGACTGCCAGATGGAGGGG
ATTCTCCCTGATCATCTGCTGGCTGGTCCCCAGCATTCACACATACATCTGGTTATACCTTGAG
GGTAGAGGCAACATATACTTGTTTTAATATCCCAAACGGTGCTCCTGGGCTGGTACCACCGTGC
TGCATGACACTGATAGACCACCATTTCTTGCCTGTAGCTTCGGAACTGGTCACCCAGCTTCCAT
TCTTCTGTGCCCCCACTGTAGGCTCCATGTGGGTGTCGGAGTGTTACTTTAAATATTAGTCATG
TCACTTCCCGGTTCAGTATTCTACAGTAACTTCTCATTTGTGCAAAATGAAATCCAGACACATG
GCCAGGCGTGGTGGCTCATGCCTGCAATTCCAGCACCCTTCCCATCCCCCACCTCCCACCGCGC
CCTTCCCATCCCCCACCTCCCACCACACCCTTCACATCCCCCATCTCCCACAGCACCCTTCACA
TCCCCCACCTCCCACCGCACCCTTCACATCCCCCACCTCCCACCGCACCCTTCACATCCCCCAC
CTCCCACCGCACCCTTCACATCCCCCACCTCCCACCACACCCTTCACATCCCCCACCTCCCACC
GCACCCTTCACATCCCCCATCTCCTGCTCCAGTCATGACACATCCCACCTTCCAATGCACCCTT
TCCATTCTTCATATTTCACTGCAGCCATTACATACCCCATCTTTTACTGCAGCCTTCACATACC
CCACCCCATCCTCTTGGGCCTCCTGGGTACTCTTTGAACATCTCAAGGCTATTTCTATCTCGGG
GCCTTTAGCTGCTGTTTTTTTTTTTTCTTAGCTTGCTTGTCATTCTCATCTTTGCAGGAGTCAC
TTCTTTACATTTACTATTCAGTTTTTTTTCTTGGTTTTACTTAATCATGTGAGCTAAAATAGGC
AACCCCCTCTATCACATCTTCCTGTTTTATTTTCTTCATATCACTTAATCTAAAATATTTTTTA
ATTTATTATTTCATATAATCTGTCACTTTCTACTAAAAATTATCTATATCATTAGCATGTAAAA
GACAGCACCAGGATAGCTGAATAGATGAGTGAATAGATCAGTGATTGTGTTAGTGAATGGATGG
ATGGATGGATGGATGGATGGATGGATGGATGGATGAATGGATAAATGGATGGATAATGGATGGC
TAGAATGATGGGTGACTGCATGGATGGAAGGATAAGTGGAGGGATGAGTGGATGGATGGATGGA
TTGATGGATGATATTTGAGTTGG

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Protein Sequences


GenBank Protein	A8MTI9	(Get FASTA)	NCBI Sequence Viewer
	EAW62808	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001337220 ⟸ NM_001350291

- Sequence:

show sequence

MGDSTHWLRSMELHSPETELSCVQTKKINQDGNKNSSNVYMGYLHFIPGGSRDDIKQVCGKPKV
VGKIYGGRDAAAGQWPWQASLLYWGSHLCGAVLIDSCWLVSTTHCFLNKSQAPKNYQVLLGNIQ
LYHQTQHTQKMSVHRIITHPDFEKLHPFGSDIAMLQLHLPMNFTSYIVPVCLPSRDMQLPSNVS
CWITGWGMLTEDHKRGVGEAGG

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Protein Domains

Peptidase S1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A8MTI9-F1-model_v2	AlphaFold	A8MTI9	1-375	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:37326	AgrOrtholog
COSMIC	PRSS47P	COSMIC
Ensembl Genes	ENSG00000276717	Ensembl, ENTREZGENE
Gene3D-CATH	2.40.10.10	UniProtKB/Swiss-Prot
	putative rabgap domain of human tbc1 domain family member 14 like domains	UniProtKB/Swiss-Prot
GTEx	ENSG00000276717	GTEx
HGNC ID	HGNC:37326	ENTREZGENE
Human Proteome Map	PRSS47P	Human Proteome Map
InterPro	Peptidase_S1_PA	UniProtKB/Swiss-Prot
	Peptidase_S1_PA_chymotrypsin	UniProtKB/Swiss-Prot
	Peptidase_S1A	UniProtKB/Swiss-Prot
	Trypsin_dom	UniProtKB/Swiss-Prot
NCBI Gene	PRSS47	ENTREZGENE
PANTHER	PROTEASE, SERINE 47	UniProtKB/Swiss-Prot
	TRANSMEMBRANE PROTEASE SERINE	UniProtKB/Swiss-Prot
Pfam	Trypsin	UniProtKB/Swiss-Prot
PRINTS	CHYMOTRYPSIN	UniProtKB/Swiss-Prot
PROSITE	TRYPSIN_DOM	UniProtKB/Swiss-Prot
SMART	Tryp_SPc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50494	UniProtKB/Swiss-Prot
UniProt	A8MTI9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-07-19	PRSS47P	serine protease 47, pseudogene	PRSS47	serine protease 47	Symbol and/or name change	19259463	PROVISIONAL
2018-01-23	PRSS47	serine protease 47		protease, serine 47	Symbol and/or name change	5135510	APPROVED
2015-11-24	PRSS47	protease, serine 47		protease, serine, 47	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar