Sox18 (SRY-box transcription factor 18) - Rat Genome Database

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Gene: Sox18 (SRY-box transcription factor 18) Chinchilla lanigera
Analyze
Symbol: Sox18
Name: SRY-box transcription factor 18
RGD ID: 9065897
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN angiogenesis (ortholog); blood vessel development (ortholog); blood vessel endothelial cell migration (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); autosomal dominant nocturnal frontal lobe epilepsy (ortholog); basal cell carcinoma (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SRY (sex determining region Y)-box 18; SRY-box 18; transcription factor SOX-18
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955528204,729 - 206,772 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sox18Chinchillaautosomal dominant nocturnal frontal lobe epilepsy  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant nocturnal frontal lobe epilepsyClinVarPMID:28492532
Sox18Chinchillabenign familial infantile seizures 6  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant nocturnal frontal lobe epilepsyClinVarPMID:28492532
Sox18Chinchillabladder exstrophy-epispadias-cloacal exstrophy complex  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Bladder exstrophy-epispadias-cloacal exstrophy complexClinVarPMID:25741868 and PMID:28492532
Sox18Chinchilladevelopmental and epileptic encephalopathy  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathyClinVarPMID:24811917 more ...
Sox18Chinchilladevelopmental and epileptic encephalopathy 33  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathy more ...ClinVarPMID:24811917 more ...
Sox18Chinchillaearly infantile epileptic encephalopathy  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Early infantile epileptic encephalopathyClinVarPMID:24811917 more ...
Sox18Chinchillagenetic disease  ISOSOX18 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Sox18Chinchillahypotrichosis-lymphedema-telangiectasia syndrome  ISOSOX18 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11701398 more ...
Sox18Chinchillahypotrichosis-lymphedema-telangiectasia-renal defect syndrome  ISOSOX18 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12740761 more ...
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sox18ChinchillaArsenic Poisoning  ISOSOX18 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16835338
Sox18Chinchillabasal cell carcinoma  ISOSOX18 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:36428691
Sox18Chinchillaskin disease  ISOSOX18 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16835338
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sox18Chinchillahypotrichosis-lymphedema-telangiectasia syndrome  ISOSOX18 (Homo sapiens)7240710 OMIM 
Sox18Chinchillahypotrichosis-lymphedema-telangiectasia-renal defect syndrome  ISOSOX18 (Homo sapiens)7240710 OMIM 


Biological Process
1 to 20 of 34 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sox18Chinchillaangiogenesis involved_inISOSOX18 (Homo sapiens)9068941 PMID:16882943UniProtPMID:16882943
Sox18Chinchillaangiogenesis acts_upstream_of_or_withinISOMGI:1075439068941 PMID:16895970MGIPMID:16895970
Sox18Chinchillablood vessel development acts_upstream_of_or_withinISOMGI:18561359068941 PMID:10742113MGIPMID:10742113
Sox18Chinchillablood vessel development acts_upstream_of_or_withinISOMGI:18561369068941 PMID:19429912MGIPMID:19429912
Sox18Chinchillablood vessel endothelial cell migration involved_inISOSOX18 (Homo sapiens)9068941 PMID:16882943UniProtPMID:16882943
Sox18Chinchillacell maturation acts_upstream_of_or_withinISOSox18 (Mus musculus)9068941 PMID:20228271MGIPMID:20228271
Sox18Chinchillaembryonic heart tube development acts_upstream_of_or_withinISOMGI:1075439068941 PMID:17610846MGIPMID:17610846
Sox18Chinchillaendocardial cell differentiation acts_upstream_of_or_withinISOMGI:1075439068941 PMID:17610846MGIPMID:17610846
Sox18Chinchillaendocardium formation acts_upstream_of_or_withinISOMGI:1075439068941 PMID:17610846MGIPMID:17610846
Sox18Chinchillaestablishment of endothelial barrier involved_inISOSOX18 (Homo sapiens)9068941 PMID:18065521UniProtPMID:18065521
Sox18Chinchillahair cycle process involved_inISOSOX18 (Homo sapiens)9068941 PMID:12740761UniProtPMID:12740761
Sox18Chinchillahair follicle development acts_upstream_of_or_withinISOMGI:18561359068941 PMID:10742113MGIPMID:10742113
Sox18Chinchillahair follicle development acts_upstream_of_or_withinISOMGI:21788099068941 PMID:11094083MGIPMID:11094083
Sox18Chinchillaheart development NOT|acts_upstream_of_or_withinISOMGI:21788099068941 PMID:11094083MGIPMID:11094083
Sox18Chinchillaheart development acts_upstream_of_or_withinISOMGI:18561359068941 PMID:10742113MGIPMID:10742113
Sox18Chinchillain utero embryonic development acts_upstream_of_or_withinISOMGI:18561369068941 PMID:19429912MGIPMID:19429912
Sox18Chinchillain utero embryonic development acts_upstream_of_or_withinISOMGI:21788099068941 PMID:18931657MGIPMID:18931657
Sox18Chinchillain utero embryonic development acts_upstream_of_or_withinISOMGI:18561359068941 PMID:10742113MGIPMID:10742113
Sox18Chinchillain utero embryonic development NOT|acts_upstream_of_or_withinISOMGI:21788099068941 PMID:11094083MGIPMID:11094083
Sox18Chinchillalymph vessel development acts_upstream_of_or_withinISOMGI:18561359068941 PMID:291594MGIPMID:291594
1 to 20 of 34 rows

Cellular Component

  

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sox18ChinchillaDNA binding enablesISOSox18 (Mus musculus)9068941 PMID:12446692MGIPMID:12446692
Sox18ChinchillaDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOSOX18 (Homo sapiens)9068941 PMID:22292085BHF-UCLPMID:22292085
Sox18ChinchillaDNA-binding transcription factor activity enablesISOSox18 (Mus musculus)9068941 PMID:10742113 more ...MGIPMID:10742113 more ...
Sox18ChinchillaDNA-binding transcription factor activity, RNA polymerase II-specific enablesISOSox18 (Mus musculus)9068941 PMID:22344693MGIPMID:22344693
Sox18Chinchillaprotein binding enablesISOPR:P202639068941 PMID:22344693MGIPMID:22344693
Sox18Chinchillaprotein binding enablesISOUniProtKB:Q8CFN59068941 PMID:11554755UniProtPMID:11554755
Sox18ChinchillaRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOSOX18 (Homo sapiens)9068941 PMID:22292085BHF-UCLPMID:22292085
Sox18Chinchillasequence-specific DNA binding enablesISOSox18 (Mus musculus)9068941 PMID:7651823MGIPMID:7651823
Sox18Chinchillasequence-specific double-stranded DNA binding enablesISOSOX18 (Homo sapiens)9068941 PMID:28473536ARUK-UCLPMID:28473536
Sox18Chinchillatranscription cis-regulatory region binding enablesISOSox18 (Mus musculus)9068941 PMID:14634005 and PMID:18931657MGIPMID:14634005 and PMID:18931657
Sox18Chinchillatranscription cis-regulatory region binding enablesISOSOX18 (Homo sapiens)9068941 PMID:18065521UniProtPMID:18065521
1 to 11 of 11 rows


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
PMID:30032202  



Sox18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955528204,729 - 206,772 (+)NCBIChiLan1.0ChiLan1.0
SOX18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382064,047,582 - 64,049,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2064,047,582 - 64,049,639 (-)EnsemblGRCh38hg38GRCh38
GRCh372062,678,935 - 62,680,992 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362062,149,523 - 62,151,423 (-)NCBINCBI36Build 36hg18NCBI36
Build 342062,149,524 - 62,151,423NCBI
Celera2059,365,185 - 59,367,085 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2059,413,178 - 59,414,764 (-)NCBIHuRef
CHM1_12062,580,086 - 62,582,001 (-)NCBICHM1_1
T2T-CHM13v2.02065,867,606 - 65,869,664 (-)NCBIT2T-CHM13v2.0
Sox18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392181,311,630 - 181,313,433 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2181,311,629 - 181,313,433 (-)EnsemblGRCm39 Ensembl
GRCm382181,669,837 - 181,671,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,669,836 - 181,671,640 (-)EnsemblGRCm38mm10GRCm38
MGSCv372181,404,542 - 181,406,345 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362181,599,249 - 181,601,015 (-)NCBIMGSCv36mm8
Celera2185,752,229 - 185,754,032 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.71NCBI
Sox18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83189,163,000 - 189,164,802 (-)NCBIGRCr8
mRatBN7.23168,785,488 - 168,787,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,785,490 - 168,787,290 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3173,164,968 - 173,166,742 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03182,124,059 - 182,125,833 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,786,438 - 178,788,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03177,177,237 - 177,179,039 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,177,310 - 177,179,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,885,768 - 180,887,570 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,820,460 - 170,822,262 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13170,726,497 - 170,728,298 (-)NCBI
Celera3163,800,470 - 163,802,272 (+)NCBICelera
Cytogenetic Map3q43NCBI
SOX18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,865,334 - 69,867,256 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,857,345 - 69,859,266 (-)NCBINHGRI_mPanPan1
SOX18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12447,494,581 - 47,496,563 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2447,494,902 - 47,496,970 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2446,628,401 - 46,630,374 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02448,633,494 - 48,635,467 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2448,633,492 - 48,635,406 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12447,478,102 - 47,480,075 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,602,566 - 47,604,541 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02448,341,512 - 48,343,485 (-)NCBIUU_Cfam_GSD_1.0
Sox18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,777,684 - 195,779,662 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651411,231,305 - 11,233,337 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651411,231,327 - 11,233,292 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOX18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,869,870 - 62,871,748 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,869,868 - 62,871,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SOX18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12195,418 - 197,221 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605047,629,355 - 47,631,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sox18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,679,091 - 29,681,049 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474129,679,274 - 29,681,069 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






RefSeq Acc Id: XM_013507511   ⟹   XP_013362965
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955528204,729 - 206,772 (+)NCBI
Sequence:
Protein RefSeqs XP_013362965 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_013362965   ⟸   XM_013507511
- Sequence:



Database
Acc Id
Source(s)
NCBI Gene Sox18 ENTREZGENE


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-06-18 Sox18  SRY-box transcription factor 18  Sox18  SRY-box 18  Symbol and/or name change 5135510 APPROVED
2016-08-16 Sox18  SRY-box 18    SRY (sex determining region Y)-box 18  Symbol and/or name change 5135510 APPROVED