Sftpd (surfactant protein D) - Rat Genome Database

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Gene: Sftpd (surfactant protein D) Chinchilla lanigera
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Symbol: Sftpd
Name: surfactant protein D
RGD ID: 9007412
Description: ENCODES a protein that exhibits galactomannan binding (ortholog); identical protein binding (ortholog); lipopolysaccharide binding (ortholog); INVOLVED IN defense response to virus (ortholog); innate immune response in mucosa (ortholog); lung alveolus development (ortholog); PARTICIPATES IN forkhead class A signaling pathway; surfactant homeostasis pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); adult respiratory distress syndrome (ortholog); asthma (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); multivesicular body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pulmonary surfactant-associated protein D
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955510213,438 - 225,896 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_004955510213,468 - 226,096 (+)NCBIChiLan1.0ChiLan1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data
Sftpd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955510213,438 - 225,896 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_004955510213,468 - 226,096 (+)NCBIChiLan1.0ChiLan1.0
SFTPD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381079,937,740 - 79,982,383 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1079,936,423 - 79,983,996 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371081,697,496 - 81,708,861 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361081,687,476 - 81,698,841 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341081,687,486 - 81,698,836NCBI
Celera1075,688,432 - 75,699,799 (-)NCBICelera
Cytogenetic Map10q22.3NCBI
HuRef1075,540,246 - 75,551,613 (-)NCBIHuRef
CHM1_11081,980,534 - 81,991,901 (-)NCBICHM1_1
T2T-CHM13v2.01080,806,973 - 80,851,624 (-)NCBIT2T-CHM13v2.0
Sftpd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391440,894,169 - 40,907,155 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1440,894,170 - 40,907,128 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381441,172,212 - 41,185,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1441,172,214 - 41,185,149 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371441,985,501 - 41,998,487 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361440,080,927 - 40,093,876 (-)NCBIMGSCv36mm8
Celera1437,332,219 - 37,345,205 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1422.36NCBI
Sftpd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81617,080,575 - 17,093,047 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1617,080,567 - 17,094,036 (-)EnsemblGRCr8
mRatBN7.21617,046,491 - 17,058,968 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,046,483 - 17,059,927 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1617,110,520 - 17,122,892 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,238,920 - 18,251,351 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01617,163,418 - 17,175,790 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1617,235,809 - 17,248,232 (-)NCBI
Lyon_Normotensive1617,108,762 - 17,121,185 (-)NCBI
Lyon_Hypertensive1617,102,717 - 17,115,140 (-)NCBI
F344_StmMcwi1617,248,013 - 17,260,436 (-)NCBI
Rnor_6.01618,753,535 - 18,766,100 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1618,745,458 - 18,766,174 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01618,621,441 - 18,633,581 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1617,272,045 - 17,284,082 (-)NCBICelera
RH 3.4 Map16167.0RGD
Cytogenetic Map16p14NCBI
SFTPD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2891,904,806 - 91,950,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11091,910,131 - 91,957,119 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01076,275,147 - 76,318,952 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11078,965,252 - 78,974,181 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1078,965,252 - 78,974,181 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
SFTPD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,394,755 - 29,407,499 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl429,394,678 - 29,407,293 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha429,519,118 - 29,533,724 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0429,696,757 - 29,711,366 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl429,696,745 - 29,709,347 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1429,566,382 - 29,580,989 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0429,769,003 - 29,783,612 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0430,123,008 - 30,137,617 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sftpd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1142,624,946 - 42,634,830 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_02440721351,337,526 - 51,349,920 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493671660,656 - 73,099 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493671660,754 - 73,010 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFTPD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1482,051,451 - 82,067,976 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11482,051,400 - 82,069,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21488,660,094 - 88,675,023 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SFTPD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1960,885,270 - 60,896,676 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366604812,161,420 - 12,172,864 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1951,809,241 - 51,820,974 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl951,811,052 - 51,820,650 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Sftpd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248416,917,067 - 6,938,594 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248416,916,849 - 6,936,077 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Sftpd
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11319,689,837 - 19,703,507 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000001212   ⟹   ENSCLAP00000001171
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955510213,438 - 225,896 (+)Ensembl
RefSeq Acc Id: XM_005407866   ⟹   XP_005407923
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955510213,649 - 226,096 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005407867   ⟹   XP_005407924
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955510213,468 - 226,096 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013506331   ⟹   XP_013361785
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955510213,649 - 226,096 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407923 (Get FASTA)   NCBI Sequence Viewer  
  XP_005407924 (Get FASTA)   NCBI Sequence Viewer  
  XP_013361785 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001171
  ENSCLAP00000001171.1
RefSeq Acc Id: XP_005407924   ⟸   XM_005407867
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UHV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005407923   ⟸   XM_005407866
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UHV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013361785   ⟸   XM_013506331
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCLAP00000001171   ⟸   ENSCLAT00000001212
Protein Domains
C-type lectin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000893 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001212 ENTREZGENE
  ENSCLAT00000001212.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
  SFTPD helical domain UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/TrEMBL
  Ca-dependent_lectin UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Collectin_CTLD UniProtKB/TrEMBL
  CTDL_fold UniProtKB/TrEMBL
  Surfac_D-trimer UniProtKB/TrEMBL
NCBI Gene Sftpd ENTREZGENE
PANTHER PULMONARY SURFACTANT-ASSOCIATED PROTEIN A UniProtKB/TrEMBL
  PULMONARY SURFACTANT-ASSOCIATED PROTEIN D UniProtKB/TrEMBL
Pfam Collagen UniProtKB/TrEMBL
  Lectin_C UniProtKB/TrEMBL
  Surfac_D-trimer UniProtKB/TrEMBL
PROSITE C_TYPE_LECTIN_1 UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/TrEMBL
SMART CLECT UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/TrEMBL
  Triple coiled coil domain of C-type lectins UniProtKB/TrEMBL
UniProt A0A8C2UHV9 ENTREZGENE, UniProtKB/TrEMBL