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Gene: Sftpd (surfactant associated protein D) Mus musculus
Symbol: Sftpd
Name: surfactant associated protein D
Description: Exhibits identical protein binding activity. Predicted to be involved in several processes, including induction of bacterial agglutination; opsonization; and regulation of phagocytosis. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Is expressed in lung; otic capsule; and skeleton. Orthologous to human SFTPD (surfactant protein D); PARTICIPATES IN surfactant homeostasis pathway; forkhead class A signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI573415; lung surfactant protein D; PSP-D; pulmonary surfactant-associated protein D; Sfpd; Sftp4; SP-D
Homo sapiens (human) : SFTPD (surfactant protein D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sftpd (surfactant protein D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sftpd (surfactant protein D)
Pan paniscus (bonobo/pygmy chimpanzee) : SFTPD (surfactant protein D)
Canis lupus familiaris (dog) : SFTPD (surfactant protein D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sftpd (surfactant protein D)
Sus scrofa (pig) : SFTPD (surfactant protein D)
Chlorocebus sabaeus (green monkey) : SFTPD (surfactant protein D)
Heterocephalus glaber (naked mole-rat) : Sftpd (surfactant protein D)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1441,172,214 - 41,185,149 (-)Ensembl
GRCm381441,172,212 - 41,185,198 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371441,985,501 - 41,998,487 (-)NCBIGRCm37mm9NCBIm37
MGSCv361440,080,927 - 40,093,876 (-)NCBImm8
Celera1437,332,219 - 37,345,205 (-)NCBICelera
Cytogenetic Map14 BNCBI
cM Map1422.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sftpd
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11287
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.