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Gene: Sftpd (surfactant associated protein D) Mus musculus
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Symbol: Sftpd
Name: surfactant associated protein D
Description: Exhibits identical protein binding activity. Predicted to be involved in several processes, including induction of bacterial agglutination; opsonization; and regulation of phagocytosis. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Is expressed in lung; otic capsule; and skeleton. Orthologous to human SFTPD (surfactant protein D); PARTICIPATES IN surfactant homeostasis pathway; forkhead class A signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI573415; lung surfactant protein D; PSP-D; pulmonary surfactant-associated protein D; Sfpd; Sftp4; SP-D
Orthologs:
Homo sapiens (human) : SFTPD (surfactant protein D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sftpd (surfactant protein D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sftpd (surfactant protein D)
Pan paniscus (bonobo/pygmy chimpanzee) : SFTPD (surfactant protein D)
Canis lupus familiaris (dog) : SFTPD (surfactant protein D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sftpd (surfactant protein D)
Sus scrofa (pig) : SFTPD (surfactant protein D)
Chlorocebus sabaeus (green monkey) : SFTPD (surfactant protein D)
Heterocephalus glaber (naked mole-rat) : Sftpd (surfactant protein D)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1441,172,214 - 41,185,149 (-)Ensembl
GRCm381441,172,212 - 41,185,198 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371441,985,501 - 41,998,487 (-)NCBIGRCm37mm9NCBIm37
MGSCv361440,080,927 - 40,093,876 (-)NCBImm8
Celera1437,332,219 - 37,345,205 (-)NCBICelera
Cytogenetic Map14 BNCBI
cM Map1422.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sftpd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11287
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.