Ucp1 (uncoupling protein 1) - Rat Genome Database

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Gene: Ucp1 (uncoupling protein 1) Chinchilla lanigera
Analyze
Symbol: Ucp1
Name: uncoupling protein 1
RGD ID: 8973102
Description: ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); long-chain fatty acid binding (ortholog); INVOLVED IN adaptive thermogenesis (ortholog); brown fat cell differentiation (ortholog); cellular response to cold (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN mitochondrial envelope (ortholog); mitochondrial inner membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial brown fat uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554283,274,810 - 3,283,237 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554283,253,363 - 3,282,518 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ucp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554283,274,810 - 3,283,237 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554283,253,363 - 3,282,518 (+)NCBIChiLan1.0ChiLan1.0
UCP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384140,559,431 - 140,568,961 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4140,559,431 - 140,568,961 (-)EnsemblGRCh38hg38GRCh38
GRCh374141,480,585 - 141,490,115 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364141,700,500 - 141,709,457 (-)NCBINCBI36Build 36hg18NCBI36
Build 344141,838,654 - 141,847,612NCBI
Celera4138,811,044 - 138,819,947 (-)NCBICelera
Cytogenetic Map4q31.1NCBI
HuRef4137,211,503 - 137,220,406 (-)NCBIHuRef
CHM1_14141,458,398 - 141,467,306 (-)NCBICHM1_1
T2T-CHM13v2.04143,879,138 - 143,888,662 (-)NCBIT2T-CHM13v2.0
Ucp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,016,977 - 84,025,085 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,016,981 - 84,025,081 (+)EnsemblGRCm39 Ensembl
GRCm38883,290,348 - 83,298,456 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,290,352 - 83,298,452 (+)EnsemblGRCm38mm10GRCm38
MGSCv37885,814,247 - 85,822,355 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36886,180,467 - 86,188,157 (+)NCBIMGSCv36mm8
Celera887,564,747 - 87,572,801 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map839.65NCBI
Ucp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,713,350 - 41,721,421 (-)NCBIGRCr8
mRatBN7.21924,808,782 - 24,816,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,808,783 - 24,816,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1931,627,843 - 31,635,958 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01932,282,249 - 32,290,366 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01934,500,303 - 34,508,418 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01924,456,976 - 24,464,808 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,456,976 - 24,464,807 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01935,434,980 - 35,442,812 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,527,548 - 26,535,621 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11926,532,373 - 26,540,447 (-)NCBI
Celera1924,348,444 - 24,356,517 (-)NCBICelera
Cytogenetic Map19q11NCBI
UCP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23138,435,652 - 138,445,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14138,823,275 - 138,832,954 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04132,921,033 - 132,930,714 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14144,230,858 - 144,239,803 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4144,230,858 - 144,240,178 (-)Ensemblpanpan1.1panPan2
UCP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1192,254,881 - 2,289,902 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha192,528,227 - 2,536,537 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0192,346,071 - 2,354,913 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl192,344,973 - 2,354,916 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1192,283,269 - 2,291,546 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0192,644,470 - 2,652,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,000,436 - 3,008,747 (+)NCBIUU_Cfam_GSD_1.0
Ucp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530149,820,808 - 49,828,140 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365357,258,343 - 7,265,398 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365357,258,146 - 7,265,475 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1886,522,028 - 86,526,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2891,981,524 - 91,985,738 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UCP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1787,492,444 - 87,502,894 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl787,492,195 - 87,502,665 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603767,019,274 - 67,029,935 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ucp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004625006155,100 - 162,551 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004625006155,179 - 162,544 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000011029   ⟹   ENSCLAP00000010895
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554283,274,810 - 3,283,237 (+)Ensembl
RefSeq Acc Id: XM_005386670   ⟹   XP_005386727
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554283,275,432 - 3,282,518 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005386671   ⟹   XP_005386728
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554283,253,363 - 3,282,518 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386727 (Get FASTA)   NCBI Sequence Viewer  
  XP_005386728 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010895
  ENSCLAP00000010895.1
RefSeq Acc Id: XP_005386728   ⟸   XM_005386671
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005386727   ⟸   XM_005386670
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V6I7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000010895   ⟸   ENSCLAT00000011029


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007517 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000011029 ENTREZGENE
  ENSCLAT00000011029.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mit_carrier UniProtKB/TrEMBL
  Mito_Metabolite_Transporter UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/TrEMBL
NCBI Gene Ucp1 ENTREZGENE
PANTHER MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED UniProtKB/TrEMBL
  PTHR45618:SF19 UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PRINTS MTUNCOUPLING UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/TrEMBL
UniProt A0A8C2V6I7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ucp1  uncoupling protein 1    uncoupling protein 1 (mitochondrial, proton carrier)  Symbol and/or name change 5135510 APPROVED