Pfkp (phosphofructokinase, platelet) - Rat Genome Database

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Gene: Pfkp (phosphofructokinase, platelet) Chinchilla lanigera
Analyze
Symbol: Pfkp
Name: phosphofructokinase, platelet
RGD ID: 8938427
Description: ENCODES a protein that exhibits 6-phosphofructokinase activity (ortholog); ATP binding (ortholog); fructose-6-phosphate binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); fructose 1,6-bisphosphate metabolic process (ortholog); fructose 6-phosphate metabolic process (ortholog); PARTICIPATES IN glycolysis pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); schizophrenia (ortholog); syndromic microphthalmia 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent 6-phosphofructokinase, platelet type
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542128,042,973 - 28,098,358 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PfkpChinchillaschizophrenia  ISOPFKP (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
PfkpChinchillasyndromic microphthalmia 5  ISOPFKP (Homo sapiens)8554872ClinVar Annotator: match by term: Anophthalmia-microphthalmia syndromeClinVarPMID:26893459
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PfkpChinchillaExperimental Liver Cirrhosis  ISOPFKP (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25380136


Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PfkpChinchillacytoplasm located_inISOPFKP (Homo sapiens)9068941 PMID:25468996BHF-UCLPMID:25468996
PfkpChinchillacytosol located_inISOPfkp (Mus musculus)9068941 PMID:2521854MGIPMID:2521854

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PfkpChinchillaglycolysis pathway   ISOPfkp (Rattus norvegicus)9068941 RGDPMID:2931076 and REF_RGD_ID:2302736

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Pfkp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542128,042,973 - 28,098,358 (-)NCBIChiLan1.0ChiLan1.0
PFKP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38103,067,548 - 3,136,805 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl103,066,333 - 3,137,718 (+)EnsemblGRCh38hg38GRCh38
GRCh37103,109,740 - 3,178,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36103,099,752 - 3,168,996 (+)NCBINCBI36Build 36hg18NCBI36
Build 34103,099,751 - 3,168,995NCBI
Celera103,056,125 - 3,124,845 (+)NCBICelera
Cytogenetic Map10p15.2NCBI
HuRef103,045,950 - 3,114,052 (+)NCBIHuRef
CHM1_1103,109,390 - 3,178,958 (+)NCBICHM1_1
T2T-CHM13v2.0103,068,649 - 3,138,082 (+)NCBIT2T-CHM13v2.0
Pfkp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39136,629,910 - 6,699,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl136,629,804 - 6,698,813 (-)EnsemblGRCm39 Ensembl
GRCm38136,579,874 - 6,649,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl136,579,768 - 6,648,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv37136,579,120 - 6,647,970 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36136,579,120 - 6,647,970 (-)NCBIMGSCv36mm8
Celera136,529,169 - 6,596,776 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map133.25NCBI
Pfkp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81768,639,749 - 68,704,055 (+)NCBIGRCr8
mRatBN7.21763,729,743 - 63,794,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1763,729,780 - 63,794,018 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1767,232,016 - 67,296,305 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01771,060,799 - 71,125,092 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01765,083,081 - 65,147,319 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01768,510,765 - 68,574,387 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1768,511,064 - 68,559,471 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01770,227,547 - 70,290,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41774,760,912 - 74,823,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11774,771,768 - 74,833,862 (+)NCBI
Celera1763,327,855 - 63,392,034 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
PFKP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2815,557,973 - 15,629,863 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11015,563,326 - 15,635,185 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0103,062,844 - 3,134,955 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1103,080,248 - 3,148,018 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl103,080,242 - 3,244,790 (+)Ensemblpanpan1.1panPan2
PFKP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1232,220,876 - 32,254,354 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl232,220,878 - 32,260,911 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha229,249,439 - 29,293,199 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0232,603,570 - 32,647,286 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl232,603,572 - 32,647,341 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1229,690,270 - 29,734,042 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0230,527,797 - 30,571,404 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,255,597 - 31,299,277 (-)NCBIUU_Cfam_GSD_1.0
Pfkp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934434,940,588 - 34,996,015 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648411,103,142 - 11,161,344 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648411,105,814 - 11,161,238 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFKP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1067,022,655 - 67,082,449 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11067,022,652 - 67,082,336 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21073,581,212 - 73,608,200 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PFKP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.193,130,701 - 3,191,590 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl93,130,566 - 3,191,576 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660518,281,360 - 8,342,269 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfkp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247757,324,662 - 7,390,271 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247757,325,032 - 7,390,200 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Ensembl Acc Id: ENSCLAT00000005201   ⟹   ENSCLAP00000005108
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000005202   ⟹   ENSCLAP00000005109
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)Ensembl
RefSeq Acc Id: XM_005383907   ⟹   XP_005383964
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383908   ⟹   XP_005383965
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513655   ⟹   XP_013369109
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,098,358 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513656   ⟹   XP_013369110
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,097,904 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513657   ⟹   XP_013369111
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513658   ⟹   XP_013369112
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005383965   ⟸   XM_005383908
- Peptide Label: isoform X3
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383964   ⟸   XM_005383907
- Peptide Label: isoform X1
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369109   ⟸   XM_013513655
- Peptide Label: isoform X2
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369110   ⟸   XM_013513656
- Peptide Label: isoform X2
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369112   ⟸   XM_013513658
- Peptide Label: isoform X5
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
Phosphofructokinase



1 to 23 of 23 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000003626 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005201 ENTREZGENE
  ENSCLAT00000005201.1 UniProtKB/TrEMBL
  ENSCLAT00000005202 ENTREZGENE
  ENSCLAT00000005202.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.450 UniProtKB/TrEMBL
  3.40.50.460 UniProtKB/TrEMBL
InterPro 6-Pfructokinase_euk UniProtKB/TrEMBL
  ATP_PFK UniProtKB/TrEMBL
  PFK_vert-type UniProtKB/TrEMBL
  Phosphofructokinase_CS UniProtKB/TrEMBL
  Phosphofructokinase_dom UniProtKB/TrEMBL
  PKF_sf UniProtKB/TrEMBL
NCBI Gene Pfkp ENTREZGENE
PANTHER ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE UniProtKB/TrEMBL
  PHOSPHOFRUCTOKINASE UniProtKB/TrEMBL
Pfam PFK UniProtKB/TrEMBL
PIRSF ATP_PFK_euk UniProtKB/TrEMBL
PRINTS PHFRCTKINASE UniProtKB/TrEMBL
PROSITE PHOSPHOFRUCTOKINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53784 UniProtKB/TrEMBL
UniProt A0A8C2USC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UTL2 ENTREZGENE, UniProtKB/TrEMBL
1 to 23 of 23 rows