Pfkp (phosphofructokinase, platelet) - Rat Genome Database

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Gene: Pfkp (phosphofructokinase, platelet) Chinchilla lanigera
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Symbol: Pfkp
Name: phosphofructokinase, platelet
RGD ID: 8938427
Description: ENCODES a protein that exhibits 6-phosphofructokinase activity (ortholog); ATP binding (ortholog); fructose-6-phosphate binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); fructose 1,6-bisphosphate metabolic process (ortholog); fructose 6-phosphate metabolic process (ortholog); PARTICIPATES IN glycolysis pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent 6-phosphofructokinase, platelet type
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542128,042,973 - 28,098,358 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pfkp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542128,042,973 - 28,098,358 (-)NCBIChiLan1.0ChiLan1.0
PFKP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38103,067,548 - 3,136,805 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl103,066,333 - 3,137,718 (+)EnsemblGRCh38hg38GRCh38
GRCh37103,109,740 - 3,178,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36103,099,752 - 3,168,996 (+)NCBINCBI36Build 36hg18NCBI36
Build 34103,099,751 - 3,168,995NCBI
Celera103,056,125 - 3,124,845 (+)NCBICelera
Cytogenetic Map10p15.2NCBI
HuRef103,045,950 - 3,114,052 (+)NCBIHuRef
CHM1_1103,109,390 - 3,178,958 (+)NCBICHM1_1
T2T-CHM13v2.0103,068,649 - 3,138,082 (+)NCBIT2T-CHM13v2.0
Pfkp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39136,629,910 - 6,699,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl136,629,804 - 6,698,813 (-)EnsemblGRCm39 Ensembl
GRCm38136,579,874 - 6,649,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl136,579,768 - 6,648,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv37136,579,120 - 6,647,970 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36136,579,120 - 6,647,970 (-)NCBIMGSCv36mm8
Celera136,529,169 - 6,596,776 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map133.25NCBI
Pfkp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81768,639,749 - 68,704,055 (+)NCBIGRCr8
mRatBN7.21763,729,743 - 63,794,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1763,729,780 - 63,794,018 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1767,232,016 - 67,296,305 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01771,060,799 - 71,125,092 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01765,083,081 - 65,147,319 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01768,510,765 - 68,574,387 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1768,511,064 - 68,559,471 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01770,227,547 - 70,290,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41774,760,912 - 74,823,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11774,771,768 - 74,833,862 (+)NCBI
Celera1763,327,855 - 63,392,034 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
PFKP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2815,557,973 - 15,629,863 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11015,563,326 - 15,635,185 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0103,062,844 - 3,134,955 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1103,080,248 - 3,148,018 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl103,080,242 - 3,244,790 (+)Ensemblpanpan1.1panPan2
PFKP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1232,220,876 - 32,254,354 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl232,220,878 - 32,260,911 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha229,249,439 - 29,293,199 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0232,603,570 - 32,647,286 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl232,603,572 - 32,647,341 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1229,690,270 - 29,734,042 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0230,527,797 - 30,571,404 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,255,597 - 31,299,277 (-)NCBIUU_Cfam_GSD_1.0
Pfkp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934434,940,588 - 34,996,015 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648411,103,142 - 11,161,344 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648411,105,814 - 11,161,238 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFKP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1067,022,655 - 67,082,449 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11067,022,652 - 67,082,336 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21073,581,212 - 73,608,200 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PFKP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.193,130,701 - 3,191,590 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl93,130,566 - 3,191,576 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660518,281,360 - 8,342,269 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfkp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247757,324,662 - 7,390,271 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247757,325,032 - 7,390,200 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000005201   ⟹   ENSCLAP00000005108
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000005202   ⟹   ENSCLAP00000005109
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542128,043,271 - 28,086,796 (-)Ensembl
RefSeq Acc Id: XM_005383907   ⟹   XP_005383964
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383908   ⟹   XP_005383965
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513655   ⟹   XP_013369109
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,098,358 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513656   ⟹   XP_013369110
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,097,904 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513657   ⟹   XP_013369111
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513658   ⟹   XP_013369112
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542128,042,973 - 28,089,031 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005383965   ⟸   XM_005383908
- Peptide Label: isoform X3
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383964   ⟸   XM_005383907
- Peptide Label: isoform X1
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369109   ⟸   XM_013513655
- Peptide Label: isoform X2
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369110   ⟸   XM_013513656
- Peptide Label: isoform X2
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369112   ⟸   XM_013513658
- Peptide Label: isoform X5
- UniProtKB: A0A8C2USC9 (UniProtKB/TrEMBL),   A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369111   ⟸   XM_013513657
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UTL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005109   ⟸   ENSCLAT00000005202
RefSeq Acc Id: ENSCLAP00000005108   ⟸   ENSCLAT00000005201
Protein Domains
Phosphofructokinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003626 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005201 ENTREZGENE
  ENSCLAT00000005201.1 UniProtKB/TrEMBL
  ENSCLAT00000005202 ENTREZGENE
  ENSCLAT00000005202.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.450 UniProtKB/TrEMBL
  3.40.50.460 UniProtKB/TrEMBL
InterPro 6-Pfructokinase_euk UniProtKB/TrEMBL
  ATP_PFK UniProtKB/TrEMBL
  PFK_vert-type UniProtKB/TrEMBL
  Phosphofructokinase_CS UniProtKB/TrEMBL
  Phosphofructokinase_dom UniProtKB/TrEMBL
  PKF_sf UniProtKB/TrEMBL
NCBI Gene Pfkp ENTREZGENE
PANTHER ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE UniProtKB/TrEMBL
  PHOSPHOFRUCTOKINASE UniProtKB/TrEMBL
Pfam PFK UniProtKB/TrEMBL
PIRSF ATP_PFK_euk UniProtKB/TrEMBL
PRINTS PHFRCTKINASE UniProtKB/TrEMBL
PROSITE PHOSPHOFRUCTOKINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53784 UniProtKB/TrEMBL
UniProt A0A8C2USC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UTL2 ENTREZGENE, UniProtKB/TrEMBL