Amfr (autocrine motility factor receptor) - Rat Genome Database

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Gene: Amfr (autocrine motility factor receptor) Chinchilla lanigera
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Symbol: Amfr
Name: autocrine motility factor receptor
RGD ID: 8930557
Description: ENCODES a protein that exhibits BAT3 complex binding (ortholog); identical protein binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); learning or memory (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN dendrite (ortholog); Derlin-1 retrotranslocation complex (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: autocrine motility factor receptor, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase AMFR
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543314,172,808 - 14,212,110 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543314,172,871 - 14,205,484 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Amfr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543314,172,808 - 14,212,110 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543314,172,871 - 14,205,484 (-)NCBIChiLan1.0ChiLan1.0
AMFR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381656,361,452 - 56,425,545 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1656,361,452 - 56,425,545 (-)EnsemblGRCh38hg38GRCh38
GRCh371656,395,364 - 56,459,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361654,952,865 - 55,016,945 (-)NCBINCBI36Build 36hg18NCBI36
Build 341654,952,864 - 55,016,804NCBI
Celera1640,892,193 - 40,957,463 (-)NCBICelera
Cytogenetic Map16q13NCBI
HuRef1642,266,003 - 42,329,606 (-)NCBIHuRef
CHM1_11657,802,735 - 57,866,433 (-)NCBICHM1_1
T2T-CHM13v2.01662,156,498 - 62,220,616 (-)NCBIT2T-CHM13v2.0
Amfr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39894,698,216 - 94,739,301 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl894,698,216 - 94,739,470 (-)EnsemblGRCm39 Ensembl
GRCm38893,971,588 - 94,012,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl893,971,588 - 94,012,842 (-)EnsemblGRCm38mm10GRCm38
MGSCv37896,495,488 - 96,536,540 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36896,861,055 - 96,901,971 (-)NCBIMGSCv36mm8
Celera898,301,641 - 98,335,290 (-)NCBICelera
Cytogenetic Map8C5NCBI
cM Map845.96NCBI
Amfr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81911,002,451 - 11,038,182 (+)NCBIGRCr8
mRatBN7.21910,996,705 - 11,032,260 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,996,099 - 11,032,247 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01911,473,538 - 11,509,500 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1911,473,541 - 11,508,102 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01911,447,902 - 11,483,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41911,434,553 - 11,467,592 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11911,417,443 - 11,471,813 (+)NCBI
Celera1910,881,564 - 10,916,023 (+)NCBICelera
Cytogenetic Map19p12NCBI
AMFR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21865,843,225 - 65,907,259 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11671,762,368 - 71,826,081 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01636,647,792 - 36,711,782 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11655,780,633 - 55,843,738 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1655,780,633 - 55,843,744 (-)Ensemblpanpan1.1panPan2
AMFR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,766,910 - 59,803,292 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,767,324 - 59,801,883 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha256,392,079 - 56,436,972 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0260,303,688 - 60,348,369 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl260,303,780 - 60,348,358 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1257,133,765 - 57,178,394 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0258,142,842 - 58,187,484 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0259,035,835 - 59,080,467 (+)NCBIUU_Cfam_GSD_1.0
Amfr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,861,780 - 50,896,114 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364758,692,844 - 8,727,385 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364758,692,969 - 8,727,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMFR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl629,366,936 - 29,413,697 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1629,366,812 - 29,417,800 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2626,739,205 - 26,753,523 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AMFR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1542,276,672 - 42,334,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl542,275,584 - 42,334,207 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604734,030,673 - 34,088,632 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amfr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624757136,283 - 179,138 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624757136,289 - 179,743 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000010851   ⟹   ENSCLAP00000010719
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543314,172,808 - 14,205,918 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000010852   ⟹   ENSCLAP00000010720
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543314,200,125 - 14,212,110 (-)Ensembl
RefSeq Acc Id: XM_013516124   ⟹   XP_013371578
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543314,172,871 - 14,205,484 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013371578 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010719
  ENSCLAP00000010719.1
  ENSCLAP00000010720.1
RefSeq Acc Id: XP_013371578   ⟸   XM_013516124
- UniProtKB: A0A8C2VCH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000010719   ⟸   ENSCLAT00000010851
Ensembl Acc Id: ENSCLAP00000010720   ⟸   ENSCLAT00000010852
Protein Domains
CUE   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007397 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010851 ENTREZGENE
  ENSCLAT00000010851.1 UniProtKB/TrEMBL
  ENSCLAT00000010852.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro AMFR_Ube2g2-bd UniProtKB/TrEMBL
  CUE UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Amfr ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE AMFR UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE RNF8 UniProtKB/TrEMBL
Pfam CUE UniProtKB/TrEMBL
  G2BR UniProtKB/TrEMBL
  zf-RING_2 UniProtKB/TrEMBL
PROSITE CUE UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART CUE UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8C2V756_CHILA UniProtKB/TrEMBL
  A0A8C2VCH4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Amfr  autocrine motility factor receptor    autocrine motility factor receptor, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED