Ttll10 (tubulin tyrosine ligase like 10) - Rat Genome Database

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Gene: Ttll10 (tubulin tyrosine ligase like 10) Chinchilla lanigera
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Symbol: Ttll10
Name: tubulin tyrosine ligase like 10
RGD ID: 8928345
Description: ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); protein-glycine ligase activity, elongating (ortholog); INVOLVED IN protein polyglycylation (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); dilated cardiomyopathy 1LL (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); microtubule cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive polyglycylase TTLL10; tubulin tyrosine ligase-like family member 10
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554869,576,174 - 9,589,297 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttll10Chinchillachromosome 1p36 deletion syndrome  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 1p36 deletion syndromeClinVarPMID:25741868
Ttll10Chinchillacongenital myasthenic syndrome 8  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital myasthenic syndrome 8ClinVarPMID:24951643 and PMID:28492532
Ttll10Chinchilladilated cardiomyopathy 1LL  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Left ventricular noncompaction 8ClinVarPMID:28492532
Ttll10ChinchillaEhlers-Danlos syndrome spondylodysplastic type 2  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome more ...ClinVarPMID:10862081 more ...
Ttll10ChinchillaGoldberg-Shprintzen syndrome  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Shprintzen-Goldberg syndromeClinVarPMID:28492532
Ttll10Chinchillaimmunodeficiency 16  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Combined immunodeficiency due to OX40 deficiencyClinVarPMID:10862081 more ...
Ttll10Chinchillaimmunodeficiency 38  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiencyClinVarPMID:10862081 more ...
Ttll10ChinchillaJoubert syndrome 25  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Joubert syndrome 25ClinVarPMID:10862081 more ...
Ttll10ChinchillaNeurodevelopmental Disorders  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Ttll10ChinchillaPeroxisome Biogenesis Disorder, Complementation Group 7  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Peroxisome biogenesis disorder and complementation group 7ClinVarPMID:10862081 more ...
Ttll10ChinchillaShprintzen-Goldberg Craniosynostosis  ISOTTLL10 (Homo sapiens)8554872ClinVar Annotator: match by term: Shprintzen-Goldberg syndromeClinVarPMID:28492532
1 to 11 of 11 rows


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttll10Chinchillaprotein polyglycylation involved_inISOTtll10 (Mus musculus)9068941 PMID:19524510UniProtPMID:19524510
Ttll10Chinchillaprotein polyglycylation NOT|involved_inISOTTLL10 (Homo sapiens)9068941 PMID:19524510UniProtPMID:19524510

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttll10Chinchillaaxoneme located_inISOTtll10 (Mus musculus)9068941 PMID:19524510UniProtPMID:19524510
Ttll10Chinchillacilium located_inISOTtll10 (Mus musculus)9068941 PMID:19524510UniProtPMID:19524510
Ttll10Chinchillamicrotubule cytoskeleton located_inISOTtll10 (Mus musculus)9068941 PMID:19524510UniProtPMID:19524510

Molecular Function

  


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074  



Ttll10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554869,576,174 - 9,589,297 (-)NCBIChiLan1.0ChiLan1.0
TTLL10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,173,880 - 1,197,936 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,173,880 - 1,197,936 (+)EnsemblGRCh38hg38GRCh38
GRCh3711,109,260 - 1,133,316 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,104,940 - 1,111,104 (+)NCBINCBI36Build 36hg18NCBI36
Celera11,449,545 - 1,473,572 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1380,667 - 405,028 (+)NCBIHuRef
CHM1_111,096,258 - 1,120,338 (+)NCBICHM1_1
T2T-CHM13v2.01602,477 - 626,317 (+)NCBIT2T-CHM13v2.0
Ttll10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,119,292 - 156,135,274 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4156,119,297 - 156,143,871 (-)EnsemblGRCm39 Ensembl
GRCm384156,034,835 - 156,050,817 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,034,840 - 156,059,414 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,408,946 - 155,424,926 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,878,635 - 154,903,144 (-)NCBIMGSCv36mm8
Celera4158,297,379 - 158,313,214 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.82NCBI
Ttll10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,912,371 - 171,937,733 (-)NCBIGRCr8
mRatBN7.25166,630,147 - 166,644,114 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,630,152 - 166,653,707 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,333,682 - 169,347,676 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,155,103 - 171,169,098 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,117,637 - 171,131,632 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,471,020 - 173,517,783 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,471,010 - 173,484,986 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,943,171 - 176,991,593 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,879,873 - 172,893,840 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,830,952 - 164,844,917 (-)NCBICelera
Cytogenetic Map5q36NCBI
TTLL10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,028,822 - 227,053,429 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,727,108 - 225,751,687 (-)NCBINHGRI_mPanPan1
PanPan1.111,131,691 - 1,143,449 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,131,691 - 1,155,349 (+)Ensemblpanpan1.1panPan2
TTLL10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,364,247 - 56,390,899 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,336,884 - 56,388,693 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,441,173 - 56,467,874 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,567,076 - 56,593,786 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,567,098 - 56,593,789 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,557,918 - 56,584,529 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,450,101 - 56,476,816 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,840,094 - 56,866,804 (+)NCBIUU_Cfam_GSD_1.0
Ttll10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,537,402 - 27,550,174 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367371,910,286 - 1,926,061 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTLL10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,497,597 - 63,511,918 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,494,759 - 63,513,884 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,031,709 - 58,042,565 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTLL10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,247,309 - 130,270,452 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605434,816,286 - 34,840,974 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttll10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248188,382,673 - 8,389,891 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Acc Id: XM_013504222   ⟹   XP_013359676
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554869,576,174 - 9,589,297 (-)NCBI
Sequence:
Protein RefSeqs XP_013359676 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000012736.1
RefSeq Acc Id: XP_013359676   ⟸   XM_013504222
- Sequence:



1 to 12 of 12 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000008793 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012884.1 UniProtKB/TrEMBL
Gene3D-CATH ATP-grasp fold, B domain UniProtKB/TrEMBL
InterPro TTL/TTLL_fam UniProtKB/TrEMBL
  TTLL10 UniProtKB/TrEMBL
NCBI Gene LOC102029519 ENTREZGENE
PANTHER INACTIVE POLYGLYCYLASE TTLL10 UniProtKB/TrEMBL
  PTHR46810 UniProtKB/TrEMBL
Pfam TTL UniProtKB/TrEMBL
PROSITE TTL UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt A0A8C2VHE8_CHILA UniProtKB/TrEMBL
1 to 12 of 12 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Ttll10  tubulin tyrosine ligase like 10    tubulin tyrosine ligase-like family member 10  Symbol and/or name change 5135510 APPROVED
2015-08-25 Ttll10  tubulin tyrosine ligase-like family member 10  LOC102029519  protein polyglycylase TTLL10-like  Symbol and/or name change 5135510 APPROVED