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Gene: Slc22a8 (solute carrier family 22 member 8) Chinchilla lanigera

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Symbol:

Slc22a8

Name:

solute carrier family 22 member 8

RGD ID:

8901704

Description:

ENCODES a protein that exhibits antiporter activity (ortholog); organic anion transmembrane transporter activity (ortholog); prostaglandin transmembrane transporter activity (ortholog); INVOLVED IN glutathione transport (ortholog); prostaglandin transport (ortholog); quaternary ammonium group transport (ortholog); PARTICIPATES IN ibuprofen pharmacodynamics pathway; ibuprofen pharmacokinetics pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Liver Cirrhosis (ortholog); Human Influenza (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

solute carrier family 22 (organic anion transporter), member 8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955599	283,929 - 300,796 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955599	284,038 - 299,603 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

Experimental Liver Cirrhosis (ISO)

Human Influenza (ISO)

intellectual disability (ISO)

leukocyte adhesion deficiency 3 (ISO)

liver cirrhosis (ISO)

steatotic liver disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glutathione transport (ISO)

prostaglandin transport (ISO)

quaternary ammonium group transport (ISO)

Cellular Component

apical plasma membrane (ISO)

basolateral plasma membrane (ISO)

Molecular Function

antiporter activity (ISO)

organic anion transmembrane transporter activity (ISO)

prostaglandin transmembrane transporter activity (ISO)

protein kinase C binding (ISO)

quaternary ammonium group transmembrane transporter activity (ISO)

solute:inorganic anion antiporter activity (ISO)

xenobiotic transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ibuprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacokinetics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Slc22a8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955599	283,929 - 300,796 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955599	284,038 - 299,603 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC22A8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	62,992,824 - 63,015,841 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	62,989,154 - 63,015,841 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	62,760,296 - 62,783,313 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	62,516,872 - 62,539,887 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	62,516,872 - 62,539,887	NCBI
Celera	11	60,084,341 - 60,107,363 (-)	NCBI		Celera
Cytogenetic Map	11	q12.3	NCBI
HuRef	11	59,089,368 - 59,112,301 (-)	NCBI		HuRef
CHM1_1	11	62,643,053 - 62,666,076 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	62,982,101 - 63,005,127 (-)	NCBI		T2T-CHM13v2.0

Slc22a8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	8,568,576 - 8,589,199 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	8,568,618 - 8,589,199 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	8,591,254 - 8,611,835 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	8,591,254 - 8,611,835 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	8,665,744 - 8,686,325 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	8,658,334 - 8,678,879 (+)	NCBI		MGSCv36	mm8
Celera	19	8,349,417 - 8,369,998 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	5.44	NCBI

Slc22a8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	214,925,506 - 214,945,516 (+)	NCBI		GRCr8
mRatBN7.2	1	205,496,331 - 205,516,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	205,498,084 - 205,517,450 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	213,904,489 - 213,921,937 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	220,941,693 - 220,959,924 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	213,634,411 - 213,652,643 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	224,799,444 - 224,818,482 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	224,800,252 - 224,818,482 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	231,735,287 - 231,755,261 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	211,269,366 - 211,287,596 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	211,427,795 - 211,446,026 (+)	NCBI
Celera	1	203,011,366 - 203,029,496 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

SLC22A8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	64,214,698 - 64,237,854 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	65,259,865 - 65,282,950 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	58,345,026 - 58,368,089 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	61,696,354 - 61,719,413 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	61,696,354 - 61,719,413 (-)	Ensembl	panpan1.1		panPan2

SLC22A8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	53,709,592 - 53,728,595 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	53,709,591 - 53,728,578 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	52,315,443 - 52,334,482 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	54,754,911 - 54,773,992 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	54,754,940 - 54,773,983 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	53,856,934 - 53,875,969 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	53,431,286 - 53,450,303 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	54,218,623 - 54,237,679 (+)	NCBI		UU_Cfam_GSD_1.0

Slc22a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	10,205,484 - 10,229,431 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	319,260 - 343,300 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	319,372 - 343,171 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC22A8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	8,782,060 - 8,800,997 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	8,782,030 - 8,800,998 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	8,124,926 - 8,143,912 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC22A8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	10,885,895 - 10,909,739 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	10,886,690 - 10,910,546 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	108,240,303 - 108,262,690 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc22a8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624926	1,374,103 - 1,388,586 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624926	1,373,804 - 1,390,248 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005414750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005414751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005414752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01076637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01062374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000000504 ⟹ ENSCLAP00000000475

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955599	283,929 - 300,796 (+)	Ensembl

RefSeq Acc Id:

XM_005414750 ⟹ XP_005414807

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955599	284,038 - 299,603 (+)	NCBI

Sequence:

show sequence

AAGGCCCAAACACAGCTTTGTTGGAGCTGAGCCGTCCAACCCAGCAGCTGCCAGACCCTACCTA
GGACAGAGCGAGGGCTCCAGTGACGGCTCCACCATCCCACCAGAGAAGACTGGCCACCAGCCAG
ATACCCCTGCAACTCCAGCTCCTCCTCCGCGGTGCCATGGCCTTCTCAGACCTCCTAGAGCGCG
TGGGCAGCATGGGCCCCTTCCAGTACCGGCACATACTCCTGCTCGCCCTCCCGATCCTTGGCAT
GGCCAACCACAACCTGCTGCAGATCTTCACAGCCACCACCCCTGCCCACCACTGCCGCCCACCC
CCCAACGCCTCTGAGGGGCCCTGGATGCCCTTCCTGGGCCCCAATGGGAAGCCTGAGAAGTGCC
TCCGCTTGGCGTACACGCCCAACACCAGCATGCCCAACGCCACCCAGGTGACCACCGAGCCCTG
CTTGGACGGCTGGGTCTACAATGCCACCAGGGACACCATTGTGACAGAGTGGGACCTGGTGTGC
AGCTCTGCCAAGATGAAGGAGATGGCGCAGTCGGTCTACATGGCAGGCATCCTGATCGGAGGCC
TGGTGCTGGGGAAGCTGTCTGACAGGTTTGGCCGCAAGCCCATCCTGACCTTCAGCTACCTCCT
GCTGGCCACCAGCGGCTCAGGCACAGCCTTCAGCCCCAGCCTCCCCACCTACATGGTCTTCCGC
TTCCTGTGTGGCTTCAGCATCTCAGGAATTACCCTGAGCACCGTCATCCTGAATGTGGAGTGGG
TGCCCACCTGGATGCGGGCCATCTCGTCCACAATGATCGGCTACTTCTACACCGTCGGCCAGTT
CCTCCTGTCCGGCCTGGCCTATGCCATCCCCCAGTGGCGCTGGCTGCAGCTGACCGTGTCTGTG
CCCTTCTTCGTCTTCTGCCTGCTGTCCTGGTGGGTCCCTGAGTCCATCCGCTGGTTGGTGCTGT
CTGGAAAGTTCTCAAAGGCCCTGCAGACACTGCAGGGCGTGGCCACCTTCAATGGCAAGAAGGA
AGAAGGGGAGAAGCTCAGCGTAGAGGAGCTGAAGCTCAACCTGCAGAAGGATATCGCCTTGGCC
AAGACCAAGTATGGTGCCATGCACCTGTTCCGGATCCCCATCCTGCGCCGCATGACTCTCTGTC
TCTCGTTGGCCTGGTTTTCCACTGGCTTTGCCTACTACAGTTTGGCCATGGGCGTGGAAGAGTT
TGGGGTGGACATCTACATCCTCCAGATCATCTTCGGAGGGGTGGACATTCCCTCCAAGTTCATC
ACCATCCTCTCCGTGAGCTACCTGGGCCGGCACATCACCCAGGCCTCCACCCTGCTCCTGGGAG
GAGGCACCATCCTGGCTCTCATCCTGATGCCCGAGGACATGCACATCCTGAGGACAGCACTGGC
TGTGTTTGGGAAGGGATGCCTGTCAAGCTCCTTCAGCTGCCTCTTCCTCTATACCAGCGAGCTC
TACCCAACAGTCATCCGGCAGACAGGCATGGGCCTCAGCAACATGTGGGCCCGCGTGGGGAGCA
TGATGGCCCCGCTAGTGAAGATCACAGGCGAGGTGCACCCTGCCATCCCCAACATCGTGTACGG
GACCATGGCCCTGCTGGGGGGCAGCACCGCCTTCTTCCTTCCAGAGACCCTCAACCGCCCTTTG
CCAGAGAACTTAGAAGACCTACAGCAGTGGTCCAAGCCAGCAAAGGAGACAAGGCTGGAGCTGG
AAGCAGAGAAAGAGGCCCAGAAGATACCTCTGAAGTCAGGCACACAGGGCGTAGGCCCCAGCTG
AGGGAGAGGCCTGCCCTGCCCCGACACCGATCCCACAGGGACCTGCCTGCCTGGGACCCTGCAG
TGGGGCCTGGGTGGGTCTGTGCCCACACACACAGCCTTCTGAGGGTGCCGTGAGACCACCCACC
TCCTCCCCCAGGGCCTCAGCCACTGCAGGCCCAGCCTCCCACCTGCCCCAGGCCCTGCTCTCCC
TCTGGCCAAGCCTCTTCCCGAGGTCCCTGGCTCAGCCCTCAGACAGCGCCCTCTTCTTGCCCTC
AACTCCTCTTTGGGATGGGAAATTTCAATAAATAGCAACAAGAGCTCAAGCAAGAA

hide sequence

RefSeq Acc Id:

XM_005414751 ⟹ XP_005414808

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955599	284,038 - 299,603 (+)	NCBI

Sequence:

show sequence

AAGGCCCAAACACAGCTTTGTTGGAGCTGAGCCGTCCAACCCAGCAGCTGCCAGACCCTACCTA
GGACAGAGCGAGGGCTCCAGTGACGGCTCCACCATCCCACCAGAGAAGACTGGCCACCAGTGGG
ACCTGGTGTGCAGCTCTGCCAAGATGAAGGAGATGGCGCAGTCGGTCTACATGGCAGGCATCCT
GATCGGAGGCCTGGTGCTGGGGAAGCTGTCTGACAGGTTTGGCCGCAAGCCCATCCTGACCTTC
AGCTACCTCCTGCTGGCCACCAGCGGCTCAGGCACAGCCTTCAGCCCCAGCCTCCCCACCTACA
TGGTCTTCCGCTTCCTGTGTGGCTTCAGCATCTCAGGAATTACCCTGAGCACCGTCATCCTGAA
TGTGGAGTGGGTGCCCACCTGGATGCGGGCCATCTCGTCCACAATGATCGGCTACTTCTACACC
GTCGGCCAGTTCCTCCTGTCCGGCCTGGCCTATGCCATCCCCCAGTGGCGCTGGCTGCAGCTGA
CCGTGTCTGTGCCCTTCTTCGTCTTCTGCCTGCTGTCCTGGTGGGTCCCTGAGTCCATCCGCTG
GTTGGTGCTGTCTGGAAAGTTCTCAAAGGCCCTGCAGACACTGCAGGGCGTGGCCACCTTCAAT
GGCAAGAAGGAAGAAGGGGAGAAGCTCAGCGTAGAGGAGCTGAAGCTCAACCTGCAGAAGGATA
TCGCCTTGGCCAAGACCAAGTATGGTGCCATGCACCTGTTCCGGATCCCCATCCTGCGCCGCAT
GACTCTCTGTCTCTCGTTGGCCTGGTTTTCCACTGGCTTTGCCTACTACAGTTTGGCCATGGGC
GTGGAAGAGTTTGGGGTGGACATCTACATCCTCCAGATCATCTTCGGAGGGGTGGACATTCCCT
CCAAGTTCATCACCATCCTCTCCGTGAGCTACCTGGGCCGGCACATCACCCAGGCCTCCACCCT
GCTCCTGGGAGGAGGCACCATCCTGGCTCTCATCCTGATGCCCGAGGACATGCACATCCTGAGG
ACAGCACTGGCTGTGTTTGGGAAGGGATGCCTGTCAAGCTCCTTCAGCTGCCTCTTCCTCTATA
CCAGCGAGCTCTACCCAACAGTCATCCGGCAGACAGGCATGGGCCTCAGCAACATGTGGGCCCG
CGTGGGGAGCATGATGGCCCCGCTAGTGAAGATCACAGGCGAGGTGCACCCTGCCATCCCCAAC
ATCGTGTACGGGACCATGGCCCTGCTGGGGGGCAGCACCGCCTTCTTCCTTCCAGAGACCCTCA
ACCGCCCTTTGCCAGAGAACTTAGAAGACCTACAGCAGTGGTCCAAGCCAGCAAAGGAGACAAG
GCTGGAGCTGGAAGCAGAGAAAGAGGCCCAGAAGATACCTCTGAAGTCAGGCACACAGGGCGTA
GGCCCCAGCTGAGGGAGAGGCCTGCCCTGCCCCGACACCGATCCCACAGGGACCTGCCTGCCTG
GGACCCTGCAGTGGGGCCTGGGTGGGTCTGTGCCCACACACACAGCCTTCTGAGGGTGCCGTGA
GACCACCCACCTCCTCCCCCAGGGCCTCAGCCACTGCAGGCCCAGCCTCCCACCTGCCCCAGGC
CCTGCTCTCCCTCTGGCCAAGCCTCTTCCCGAGGTCCCTGGCTCAGCCCTCAGACAGCGCCCTC
TTCTTGCCCTCAACTCCTCTTTGGGATGGGAAATTTCAATAAATAGCAACAAGAGCTCAAGCAA
GAA

hide sequence

RefSeq Acc Id:

XM_005414752 ⟹ XP_005414809

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955599	284,038 - 299,603 (+)	NCBI

Sequence:

show sequence

AAGGCCCAAACACAGCTTTGTTGGAGCTGAGCCGTCCAACCCAGCAGCTGCCAGACCCTACCTA
GGACAGAGCGAGGGCTCCAGTGACGGCTCCACCATCCCACCAGAGAAGACTGGCCACCAGATAC
CCCTGCAACTCCAGCTCCTCCTCCGCGGTGCCATGGCCTTCTCAGACCTCCTAGAGCGCGTGGG
CAGCATGGGCCCCTTCCAGTACCGGCACATACTCCTGCTCGCCCTCCCGATCCTTGGCATGGCC
AACCACAACCTGCTGCAGATCTTCACAGCCACCACCCCTGCCCACCACTGCCGCCCACCCCCCA
ACGCCTCTGAGGGGCCCTGGATGCCCTTCCTGGGCCCCAATGGGAAGCCTGAGAAGTGCCTCCG
CTTGGCGTACACGCCCAACACCAGCATGCCCAACGCCACCCAGGTGACCACCGAGCCCTGCTTG
GACGGCTGGGTCTACAATGCCACCAGGGACACCATTGTGACAGAGTGGGACCTGGTGTGCAGCT
CTGCCAAGATGAAGGAGATGGCGCAGTCGGTCTACATGGCAGGCATCCTGATCGGAGGCCTGGT
GCTGGGGAAGCTGTCTGACAGGTTTGGCCGCAAGCCCATCCTGACCTTCAGCTACCTCCTGCTG
GCCACCAGCGGCTCAGGCACAGCCTTCAGCCCCAGCCTCCCCACCTACATGGTCTTCCGCTTCC
TGTGTGGCTTCAGCATCTCAGGAATTACCCTGAGCACCGTCATCCTGAATGTGGAGTGGGTGCC
CACCTGGATGCGGGCCATCTCGTCCACAATGATCGGCTACTTCTACACCGTCGGCCAGTTCCTC
CTGTCCGGCCTGGCCTATGCCATCCCCCAGTGGCGCTGGCTGCAGCTGACCGTGTCTGTGCCCT
TCTTCGTCTTCTGCCTGCTGTCCTGGTGGGTCCCTGAGTCCATCCGCTGGTTGGTGCTGTCTGG
AAAGTTCTCAAAGGCCCTGCAGACACTGCAGGGCGTGGCCACCTTCAATGGCAAGAAGGAAGAA
GGGGAGAAGCTCAGCGTAGAGGAGCTGAAGCTCAACCTGCAGAAGGATATCGCCTTGGCCAAGA
CCAAGTATGGTGCCATGCACCTGTTCCGGATCCCCATCCTGCGCCGCATGACTCTCTGTCTCTC
GTTGGCCTGGTTTTCCACTGGCTTTGCCTACTACAGTTTGGCCATGGGCGTGGAAGAGTTTGGG
GTGGACATCTACATCCTCCAGATCATCTTCGGAGGGGTGGACATTCCCTCCAAGTTCATCACCA
TCCTCTCCGTGAGCTACCTGGGCCGGCACATCACCCAGGCCTCCACCCTGCTCCTGGGAGGAGG
CACCATCCTGGCTCTCATCCTGATGCCCGAGGACATGCACATCCTGAGGACAGCACTGGCTGTG
TTTGGGAAGGGATGCCTGTCAAGCTCCTTCAGCTGCCTCTTCCTCTATACCAGCGAGCTCTACC
CAACAGTCATCCGGCAGACAGGCATGGGCCTCAGCAACATGTGGGCCCGCGTGGGGAGCATGAT
GGCCCCGCTAGTGAAGATCACAGGCGAGGTGCACCCTGCCATCCCCAACATCGTGTACGGGACC
ATGGCCCTGCTGGGGGGCAGCACCGCCTTCTTCCTTCCAGAGACCCTCAACCGCCCTTTGCCAG
AGAACTTAGAAGACCTACAGCAGTGGTCCAAGCCAGCAAAGGAGACAAGGCTGGAGCTGGAAGC
AGAGAAAGAGGCCCAGAAGATACCTCTGAAGTCAGGCACACAGGGCGTAGGCCCCAGCTGAGGG
AGAGGCCTGCCCTGCCCCGACACCGATCCCACAGGGACCTGCCTGCCTGGGACCCTGCAGTGGG
GCCTGGGTGGGTCTGTGCCCACACACACAGCCTTCTGAGGGTGCCGTGAGACCACCCACCTCCT
CCCCCAGGGCCTCAGCCACTGCAGGCCCAGCCTCCCACCTGCCCCAGGCCCTGCTCTCCCTCTG
GCCAAGCCTCTTCCCGAGGTCCCTGGCTCAGCCCTCAGACAGCGCCCTCTTCTTGCCCTCAACT
CCTCTTTGGGATGGGAAATTTCAATAAATAGCAACAAGAGCTCAAGCAAGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005414807	(Get FASTA)	NCBI Sequence Viewer
	XP_005414808	(Get FASTA)	NCBI Sequence Viewer
	XP_005414809	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000000475
	ENSCLAP00000000475.1

RefSeq Acc Id:	XP_005414809 ⟸ XM_005414752
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UG70 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAFSDLLERVGSMGPFQYRHILLLALPILGMANHNLLQIFTATTPAHHCRPPPNASEGPWMPFL GPNGKPEKCLRLAYTPNTSMPNATQVTTEPCLDGWVYNATRDTIVTEWDLVCSSAKMKEMAQSV YMAGILIGGLVLGKLSDRFGRKPILTFSYLLLATSGSGTAFSPSLPTYMVFRFLCGFSISGITL STVILNVEWVPTWMRAISSTMIGYFYTVGQFLLSGLAYAIPQWRWLQLTVSVPFFVFCLLSWWV PESIRWLVLSGKFSKALQTLQGVATFNGKKEEGEKLSVEELKLNLQKDIALAKTKYGAMHLFRI PILRRMTLCLSLAWFSTGFAYYSLAMGVEEFGVDIYILQIIFGGVDIPSKFITILSVSYLGRHI TQASTLLLGGGTILALILMPEDMHILRTALAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGL SNMWARVGSMMAPLVKITGEVHPAIPNIVYGTMALLGGSTAFFLPETLNRPLPENLEDLQQWSK PAKETRLELEAEKEAQKIPLKSGTQGVGPS hide sequence

RefSeq Acc Id:	XP_005414807 ⟸ XM_005414750
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UG70 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAFSDLLERVGSMGPFQYRHILLLALPILGMANHNLLQIFTATTPAHHCRPPPNASEGPWMPFL GPNGKPEKCLRLAYTPNTSMPNATQVTTEPCLDGWVYNATRDTIVTEWDLVCSSAKMKEMAQSV YMAGILIGGLVLGKLSDRFGRKPILTFSYLLLATSGSGTAFSPSLPTYMVFRFLCGFSISGITL STVILNVEWVPTWMRAISSTMIGYFYTVGQFLLSGLAYAIPQWRWLQLTVSVPFFVFCLLSWWV PESIRWLVLSGKFSKALQTLQGVATFNGKKEEGEKLSVEELKLNLQKDIALAKTKYGAMHLFRI PILRRMTLCLSLAWFSTGFAYYSLAMGVEEFGVDIYILQIIFGGVDIPSKFITILSVSYLGRHI TQASTLLLGGGTILALILMPEDMHILRTALAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGL SNMWARVGSMMAPLVKITGEVHPAIPNIVYGTMALLGGSTAFFLPETLNRPLPENLEDLQQWSK PAKETRLELEAEKEAQKIPLKSGTQGVGPS hide sequence

RefSeq Acc Id:

XP_005414808 ⟸ XM_005414751

- Peptide Label:

isoform X2

- Sequence:

show sequence

MKEMAQSVYMAGILIGGLVLGKLSDRFGRKPILTFSYLLLATSGSGTAFSPSLPTYMVFRFLCG
FSISGITLSTVILNVEWVPTWMRAISSTMIGYFYTVGQFLLSGLAYAIPQWRWLQLTVSVPFFV
FCLLSWWVPESIRWLVLSGKFSKALQTLQGVATFNGKKEEGEKLSVEELKLNLQKDIALAKTKY
GAMHLFRIPILRRMTLCLSLAWFSTGFAYYSLAMGVEEFGVDIYILQIIFGGVDIPSKFITILS
VSYLGRHITQASTLLLGGGTILALILMPEDMHILRTALAVFGKGCLSSSFSCLFLYTSELYPTV
IRQTGMGLSNMWARVGSMMAPLVKITGEVHPAIPNIVYGTMALLGGSTAFFLPETLNRPLPENL
EDLQQWSKPAKETRLELEAEKEAQKIPLKSGTQGVGPS

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Ensembl Acc Id:

ENSCLAP00000000475 ⟸ ENSCLAT00000000504

Protein Domains

Major facilitator superfamily (MFS) profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000000390	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000000504	ENTREZGENE
	ENSCLAT00000000504.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/TrEMBL
InterPro	MFS_dom	UniProtKB/TrEMBL
	MFS_sugar_transport-like	UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/TrEMBL
	Orgcat_transp/SVOP	UniProtKB/TrEMBL
	Sugar_transporter_CS	UniProtKB/TrEMBL
NCBI Gene	Slc22a8	ENTREZGENE
PANTHER	SOLUTE CARRIER FAMILY 22 MEMBER	UniProtKB/TrEMBL
	SOLUTE CARRIER FAMILY 22 MEMBER 8	UniProtKB/TrEMBL
Pfam	Sugar_tr	UniProtKB/TrEMBL
PROSITE	MFS	UniProtKB/TrEMBL
	SUGAR_TRANSPORT_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103473	UniProtKB/TrEMBL
UniProt	A0A8C2UG70	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Slc22a8	solute carrier family 22 member 8		solute carrier family 22 (organic anion transporter), member 8	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB