Aldh8a1 (aldehyde dehydrogenase 8 family member A1) - Rat Genome Database

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Gene: Aldh8a1 (aldehyde dehydrogenase 8 family member A1) Chinchilla lanigera
Analyze
Symbol: Aldh8a1
Name: aldehyde dehydrogenase 8 family member A1
RGD ID: 8889595
Description: ENCODES a protein that exhibits retinal dehydrogenase activity (ortholog); INVOLVED IN 9-cis-retinoic acid biosynthetic process (ortholog); retinal metabolic process (ortholog); retinoic acid metabolic process (ortholog); ASSOCIATED WITH cholestasis (ortholog); Familial Behcet-Like Autoinflammatory Syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aldehyde dehydrogenase 8 family, member A1; aldehyde dehydrogenase family 8 member A1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,773,861 - 1,794,328 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,773,884 - 1,794,325 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Aldh8a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,773,861 - 1,794,328 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,773,884 - 1,794,325 (+)NCBIChiLan1.0ChiLan1.0
ALDH8A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386134,917,393 - 134,950,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6134,917,393 - 134,950,115 (-)EnsemblGRCh38hg38GRCh38
GRCh376135,238,531 - 135,271,239 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366135,280,221 - 135,312,937 (-)NCBINCBI36Build 36hg18NCBI36
Build 346135,280,221 - 135,312,937NCBI
Celera6135,978,855 - 136,011,613 (-)NCBICelera
Cytogenetic Map6q23.3NCBI
HuRef6132,802,624 - 132,835,473 (-)NCBIHuRef
CHM1_16135,500,243 - 135,532,981 (-)NCBICHM1_1
T2T-CHM13v2.06136,105,650 - 136,138,351 (-)NCBIT2T-CHM13v2.0
Aldh8a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391021,253,199 - 21,272,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1021,253,190 - 21,272,484 (+)EnsemblGRCm39 Ensembl
GRCm381021,377,300 - 21,396,578 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1021,377,291 - 21,396,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv371021,097,106 - 21,116,384 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361021,066,707 - 21,085,994 (+)NCBIMGSCv36mm8
Celera1021,271,834 - 21,291,207 (+)NCBICelera
Cytogenetic Map10A3NCBI
cM Map109.75NCBI
Aldh8a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8118,003,507 - 18,022,952 (+)NCBIGRCr8
mRatBN7.2116,183,940 - 16,203,385 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,183,940 - 16,203,385 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,939,802 - 15,967,859 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,941,695 - 21,969,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,165,019 - 16,193,076 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0116,910,043 - 16,929,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,910,069 - 16,930,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0118,065,355 - 18,084,421 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,750,783 - 16,769,899 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera114,601,982 - 14,621,191 (+)NCBICelera
Cytogenetic Map1p12NCBI
ALDH8A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25154,892,189 - 154,939,701 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16152,790,595 - 152,847,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06132,685,904 - 132,732,194 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16136,782,957 - 136,815,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6136,782,957 - 136,815,611 (-)Ensemblpanpan1.1panPan2
ALDH8A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,672,422 - 27,695,029 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,673,024 - 27,694,868 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,553,032 - 28,575,378 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0127,830,092 - 27,852,485 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl127,830,696 - 27,852,360 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1127,714,409 - 27,736,977 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0127,594,758 - 27,617,127 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0127,905,932 - 27,928,311 (-)NCBIUU_Cfam_GSD_1.0
Aldh8a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946122,783,100 - 122,801,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365602,562,748 - 2,580,201 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365602,562,394 - 2,580,261 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH8A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl129,060,701 - 29,083,143 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1129,060,682 - 29,083,815 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,551,894 - 32,561,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH8A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11338,489,459 - 38,521,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1338,490,181 - 38,522,087 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604010,689,605 - 10,721,369 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh8a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248862,702,960 - 2,722,357 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248862,702,328 - 2,721,954 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000007789   ⟹   ENSCLAP00000007670
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554391,773,861 - 1,794,328 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000007790   ⟹   ENSCLAP00000007671
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554391,773,999 - 1,786,936 (+)Ensembl
RefSeq Acc Id: XM_005390500   ⟹   XP_005390557
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554391,773,884 - 1,794,325 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013517432   ⟹   XP_013372886
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554391,773,884 - 1,794,325 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005390557 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372886 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007670
  ENSCLAP00000007670.1
  ENSCLAP00000007671.1
RefSeq Acc Id: XP_005390557   ⟸   XM_005390500
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V501 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013372886   ⟸   XM_013517432
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSCLAP00000007670   ⟸   ENSCLAT00000007789
Ensembl Acc Id: ENSCLAP00000007671   ⟸   ENSCLAT00000007790
Protein Domains
Aldehyde dehydrogenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005380 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007789 ENTREZGENE
  ENSCLAT00000007789.1 UniProtKB/TrEMBL
  ENSCLAT00000007790.1 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
NCBI Gene Aldh8a1 ENTREZGENE
PANTHER 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE UniProtKB/TrEMBL
  2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/TrEMBL
UniProt A0A8C2UZK5_CHILA UniProtKB/TrEMBL
  A0A8C2V501 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Aldh8a1  aldehyde dehydrogenase 8 family member A1    aldehyde dehydrogenase 8 family, member A1  Symbol and/or name change 5135510 APPROVED