ALDH8A1 (aldehyde dehydrogenase 8 family member A1) - Rat Genome Database

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Gene: ALDH8A1 (aldehyde dehydrogenase 8 family member A1) Sus scrofa
Analyze
Symbol: ALDH8A1
Name: aldehyde dehydrogenase 8 family member A1
RGD ID: 14099072
Description: ENCODES a protein that exhibits oxidoreductase activity (inferred); oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (inferred); retinal dehydrogenase activity (inferred); INVOLVED IN 9-cis-retinoic acid biosynthetic process (ortholog); ASSOCIATED WITH cholestasis (ortholog); familial Behcet-like autoinflammatory syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aldehyde dehydrogenase 8A1; aldehyde dehydrogenase family 8 member A1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl129,060,701 - 29,083,143 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1129,060,682 - 29,083,815 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,551,894 - 32,561,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
ALDH8A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl129,060,701 - 29,083,143 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1129,060,682 - 29,083,815 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,551,894 - 32,561,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH8A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386134,917,393 - 134,950,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6134,917,393 - 134,950,115 (-)EnsemblGRCh38hg38GRCh38
GRCh376135,238,531 - 135,271,239 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366135,280,221 - 135,312,937 (-)NCBINCBI36Build 36hg18NCBI36
Build 346135,280,221 - 135,312,937NCBI
Celera6135,978,855 - 136,011,613 (-)NCBICelera
Cytogenetic Map6q23.3NCBI
HuRef6132,802,624 - 132,835,473 (-)NCBIHuRef
CHM1_16135,500,243 - 135,532,981 (-)NCBICHM1_1
T2T-CHM13v2.06136,105,650 - 136,138,351 (-)NCBIT2T-CHM13v2.0
Aldh8a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391021,253,199 - 21,272,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1021,253,190 - 21,272,484 (+)EnsemblGRCm39 Ensembl
GRCm381021,377,300 - 21,396,578 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1021,377,291 - 21,396,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv371021,097,106 - 21,116,384 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361021,066,707 - 21,085,994 (+)NCBIMGSCv36mm8
Celera1021,271,834 - 21,291,207 (+)NCBICelera
Cytogenetic Map10A3NCBI
Aldh8a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2116,183,940 - 16,203,385 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,183,940 - 16,203,385 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,939,802 - 15,967,859 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0121,941,695 - 21,969,752 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0116,165,019 - 16,193,076 (+)NCBIRnor_WKY
Rnor_6.0116,910,043 - 16,929,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,910,069 - 16,930,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0118,065,355 - 18,084,421 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,750,783 - 16,769,899 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera114,601,982 - 14,621,191 (+)NCBICelera
Cytogenetic Map1p12NCBI
Aldh8a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,773,861 - 1,794,328 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,773,884 - 1,794,325 (+)NCBIChiLan1.0ChiLan1.0
ALDH8A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16136,782,957 - 136,815,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6136,782,957 - 136,815,611 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06132,685,904 - 132,732,194 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ALDH8A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,672,422 - 27,695,029 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,673,024 - 27,694,868 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,553,032 - 28,575,378 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0127,830,092 - 27,852,485 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl127,830,696 - 27,852,360 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1127,714,409 - 27,736,977 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0127,594,758 - 27,617,127 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0127,905,932 - 27,928,311 (-)NCBIUU_Cfam_GSD_1.0
Aldh8a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946122,783,100 - 122,801,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365602,562,748 - 2,580,201 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365602,562,394 - 2,580,261 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH8A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11338,489,459 - 38,521,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1338,490,181 - 38,522,087 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604010,689,605 - 10,721,369 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh8a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248862,702,960 - 2,722,357 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248862,702,328 - 2,721,954 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system renal system reproductive system
High
Medium 2
Low 1 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000029261   ⟹   ENSSSCP00000026279
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl129,060,701 - 29,079,324 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000086170   ⟹   ENSSSCP00000072988
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl129,060,710 - 29,083,143 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000104897   ⟹   ENSSSCP00000076505
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl129,060,732 - 29,081,979 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000106764   ⟹   ENSSSCP00000080766
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl129,060,732 - 29,081,979 (+)Ensembl
RefSeq Acc Id: XM_021087621   ⟹   XP_020943280
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1129,060,682 - 29,083,815 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020943280 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABC58679 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020943280   ⟸   XM_021087621
- UniProtKB: A0A481BBL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000026279   ⟸   ENSSSCT00000029261
RefSeq Acc Id: ENSSSCP00000072988   ⟸   ENSSSCT00000086170
RefSeq Acc Id: ENSSSCP00000080766   ⟸   ENSSSCT00000106764
RefSeq Acc Id: ENSSSCP00000076505   ⟸   ENSSSCT00000104897
Protein Domains
Aldedh


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000028115 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000026279.3 UniProtKB/TrEMBL
  ENSSSCP00000072988.1 UniProtKB/TrEMBL
  ENSSSCP00000080766 ENTREZGENE
Ensembl Transcript ENSSSCT00000029261.3 UniProtKB/TrEMBL
  ENSSSCT00000086170.1 UniProtKB/TrEMBL
  ENSSSCT00000106764 ENTREZGENE
Gene3D-CATH 3.40.309.10 UniProtKB/TrEMBL
  3.40.605.10 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
NCBI Gene ALDH8A1 ENTREZGENE
Pfam Aldedh UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/TrEMBL
UniProt A0A481BBL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2RL67_PIG UniProtKB/TrEMBL
  I3LQA1_PIG UniProtKB/TrEMBL
  Q15I70_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85244 ENTREZGENE