Cpsf1 (cleavage and polyadenylation specific factor 1) - Rat Genome Database

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Gene: Cpsf1 (cleavage and polyadenylation specific factor 1) Chinchilla lanigera
Analyze
Symbol: Cpsf1
Name: cleavage and polyadenylation specific factor 1
RGD ID: 8854232
Description: ENCODES a protein that exhibits enzyme binding (ortholog); mRNA 3'-UTR AU-rich region binding (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); Disease Progression (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); FOUND IN mRNA cleavage and polyadenylation specificity factor complex (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor subunit 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,024,406 - 3,039,425 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,024,324 - 3,039,004 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cpsf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,024,406 - 3,039,425 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,024,324 - 3,039,004 (-)NCBIChiLan1.0ChiLan1.0
CPSF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,393,231 - 144,409,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,393,229 - 144,409,335 (-)EnsemblGRCh38hg38GRCh38
GRCh378145,618,446 - 145,634,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,589,254 - 145,605,541 (-)NCBINCBI36Build 36hg18NCBI36
Build 348145,589,253 - 145,605,541NCBI
Celera8141,792,905 - 141,809,167 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,731,448 - 140,747,966 (-)NCBIHuRef
CHM1_18145,656,550 - 145,673,024 (-)NCBICHM1_1
T2T-CHM13v2.08145,562,868 - 145,579,148 (-)NCBIT2T-CHM13v2.0
Cpsf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,480,008 - 76,491,861 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,480,003 - 76,491,791 (-)EnsemblGRCm39 Ensembl
GRCm381576,595,808 - 76,607,661 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,595,803 - 76,607,591 (-)EnsemblGRCm38mm10GRCm38
MGSCv371576,426,238 - 76,438,021 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,423,063 - 76,434,809 (-)NCBIMGSCv36mm8
Celera1578,089,201 - 78,101,206 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.13NCBI
Cpsf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,200,078 - 110,210,644 (-)NCBIGRCr8
mRatBN7.27108,319,429 - 108,330,018 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,319,434 - 108,329,934 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,061,260 - 110,071,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,284,973 - 112,295,415 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,245,683 - 112,256,252 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,661,779 - 117,672,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,661,661 - 117,672,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,649,863 - 117,660,456 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,647,975 - 114,658,568 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,682,284 - 114,692,737 (-)NCBI
Celera7104,669,635 - 104,680,226 (-)NCBICelera
Cytogenetic Map7q34NCBI
CPSF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,882,889 - 161,900,722 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,411,908 - 137,429,795 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,158,494 - 141,176,354 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,149,253 - 144,166,183 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,148,075 - 144,166,043 (-)Ensemblpanpan1.1panPan2
CPSF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,817,440 - 37,827,868 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,817,442 - 37,825,212 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,780,111 - 37,793,256 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,293,061 - 38,306,204 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,293,061 - 38,306,328 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,984,868 - 37,998,022 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,093,511 - 38,106,668 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,569,886 - 38,583,035 (-)NCBIUU_Cfam_GSD_1.0
Cpsf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303419,543 - 431,194 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,849,329 - 7,857,214 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,848,846 - 7,857,291 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPSF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14382,887 - 393,732 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24473,501 - 482,157 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CPSF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,602,549 - 138,618,802 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,602,835 - 138,617,071 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,238,282 - 1,255,392 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpsf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,444,386 - 12,457,864 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,444,371 - 12,457,864 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000017912   ⟹   ENSCLAP00000017737
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554543,024,406 - 3,039,425 (-)Ensembl
RefSeq Acc Id: XM_005395878   ⟹   XP_005395935
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554543,024,324 - 3,039,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005395879   ⟹   XP_005395936
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554543,024,417 - 3,039,001 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005395935 (Get FASTA)   NCBI Sequence Viewer  
  XP_005395936 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017737
  ENSCLAP00000017737.1
RefSeq Acc Id: XP_005395935   ⟸   XM_005395878
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005395936   ⟸   XM_005395879
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VM67 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000017737   ⟸   ENSCLAT00000017912
Protein Domains
Cleavage/polyadenylation specificity factor A


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017912 ENTREZGENE
  ENSCLAT00000017912.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Cleavage/polyA-sp_fac_asu_C UniProtKB/TrEMBL
  Cleavage/polyA-sp_fac_asu_N UniProtKB/TrEMBL
  RSE1/DDB1/CFT1/CPSF1 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Cpsf1 ENTREZGENE
PANTHER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 UniProtKB/TrEMBL
  DNA REPAIR/RNA PROCESSING CPSF FAMILY UniProtKB/TrEMBL
Pfam CPSF_A UniProtKB/TrEMBL
  MMS1_N UniProtKB/TrEMBL
UniProt A0A8C2VM67 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Cpsf1  cleavage and polyadenylation specific factor 1    cleavage and polyadenylation specific factor 1, 160kDa  Symbol and/or name change 5135510 APPROVED