Creb3l2 (cAMP responsive element binding protein 3 like 2) - Rat Genome Database

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Gene: Creb3l2 (cAMP responsive element binding protein 3 like 2) Chinchilla lanigera
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Symbol: Creb3l2
Name: cAMP responsive element binding protein 3 like 2
RGD ID: 8835404
Description: ENCODES a protein that exhibits cAMP response element binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cartilage development (ortholog); chondrocyte differentiation (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN chromatin (ortholog); endoplasmic reticulum (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cAMP responsive element binding protein 3-like 2; cyclic AMP-responsive element-binding protein 3-like protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554945,045,272 - 5,089,121 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554945,014,509 - 5,094,220 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Creb3l2Chinchillapleomorphic xanthoastrocytoma  ISORGD:13144298554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358


Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Creb3l2Chinchillacartilage development involved_inISORGD:15503809068941 PMID:19767744UniProtPMID:19767744
Creb3l2Chinchillachondrocyte differentiation involved_inISORGD:15503809068941 PMID:19767744UniProtPMID:19767744
Creb3l2Chinchillaendoplasmic reticulum to Golgi vesicle-mediated transport involved_inISORGD:15503809068941 PMID:19767744UniProtPMID:19767744
Creb3l2Chinchillapositive regulation of DNA-templated transcription involved_inISORGD:13144299068941 PMID:17178827UniProtPMID:17178827
Creb3l2Chinchillapositive regulation of DNA-templated transcription involved_inISORGD:15503809068941 PMID:19767744UniProtPMID:19767744
Creb3l2Chinchillapositive regulation of gene expression  ISORGD:13060409068941 RGDPMID:23842743|REF_RGD_ID:13515084
Creb3l2Chinchillapositive regulation of neuron projection development  ISORGD:13060409068941 RGDPMID:23842743|REF_RGD_ID:13515084
Creb3l2Chinchillapositive regulation of transcription by RNA polymerase II involved_inISORGD:15503809068941 PMID:17178827NTNU_SBPMID:17178827
Creb3l2Chinchillaresponse to endoplasmic reticulum stress  ISORGD:13060409068941 RGDPMID:19666046|REF_RGD_ID:13515083
Creb3l2Chinchillaresponse to endoplasmic reticulum stress involved_inISORGD:13144299068941 PMID:17178827UniProtPMID:17178827
1 to 10 of 10 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Creb3l2Chinchillachromatin  ISORGD:13060409068941 RGDPMID:23842743|REF_RGD_ID:13515084
Creb3l2Chinchillaendoplasmic reticulum located_inISORGD:13144299068941 PMID:17178827HPAGO_REF:0000052|PMID:17178827
Creb3l2Chinchillanucleoplasm located_inISORGD:13144299068941 HPAGO_REF:0000052
Creb3l2Chinchillanucleus located_inISORGD:13144299068941 PMID:17178827UniProtPMID:17178827
Creb3l2Chinchillaperinuclear endoplasmic reticulum  ISORGD:13060409068941 RGDPMID:23842743|REF_RGD_ID:13515084

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Creb3l2ChinchillacAMP response element binding enablesISORGD:13144299068941 PMID:17178827UniProtPMID:17178827
Creb3l2ChinchillacAMP response element binding enablesISORGD:15503809068941 PMID:19767744UniProtPMID:19767744
Creb3l2ChinchillaDNA-binding transcription activator activity, RNA polymerase II-specific  ISORGD:13060409068941 RGDPMID:23842743|REF_RGD_ID:13515084
Creb3l2ChinchillaDNA-binding transcription activator activity, RNA polymerase II-specific enablesISORGD:15503809068941 PMID:17178827NTNU_SBPMID:17178827
Creb3l2ChinchillaRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISORGD:15503809068941 PMID:17178827NTNU_SBPMID:17178827
Creb3l2Chinchillatranscription cis-regulatory region binding enablesISORGD:13144299068941 PMID:17178827UniProtPMID:17178827
Creb3l2Chinchillatranscription cis-regulatory region binding enablesISORGD:15503809068941 PMID:19767744UniProtPMID:19767744

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Creb3l2Chinchillaendoplasmic reticulum stress - the unfolded protein response pathway  ISORGD:13144299068941 RGDPMID:22733998|REF_RGD_ID:10450872

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:30032202  



Creb3l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554945,045,272 - 5,089,121 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554945,014,509 - 5,094,220 (+)NCBIChiLan1.0ChiLan1.0
CREB3L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387137,874,979 - 138,002,086 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7137,874,979 - 138,002,086 (-)EnsemblGRCh38hg38GRCh38
GRCh377137,559,725 - 137,686,832 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367137,210,265 - 137,337,386 (-)NCBINCBI36Build 36hg18NCBI36
Build 347137,016,979 - 137,144,101NCBI
Celera7132,298,692 - 132,425,654 (-)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7131,867,554 - 131,994,857 (-)NCBIHuRef
CHM1_17137,493,293 - 137,620,361 (-)NCBICHM1_1
T2T-CHM13v2.07139,184,080 - 139,311,621 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27136,905,109 - 137,032,069 (-)NCBI
Creb3l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39637,307,956 - 37,419,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl637,304,190 - 37,419,081 (-)EnsemblGRCm39 Ensembl
GRCm38637,327,255 - 37,442,276 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl637,327,255 - 37,442,146 (-)EnsemblGRCm38mm10GRCm38
MGSCv37637,281,021 - 37,392,148 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36637,260,627 - 37,371,747 (-)NCBIMGSCv36mm8
Celera637,307,243 - 37,429,201 (-)NCBICelera
Cytogenetic Map6B1NCBI
cM Map616.18NCBI
Creb3l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8466,874,623 - 66,990,962 (-)NCBIGRCr8
mRatBN7.2465,907,570 - 66,112,078 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl465,907,655 - 66,023,763 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx470,849,613 - 70,965,757 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0466,770,691 - 66,886,837 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0465,160,628 - 65,276,768 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0464,869,285 - 64,981,519 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl464,869,026 - 64,981,384 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0464,691,125 - 64,803,069 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4464,703,458 - 64,816,668 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1464,979,587 - 65,092,798 (-)NCBI
Celera460,932,138 - 61,044,664 (-)NCBICelera
Cytogenetic Map4q22NCBI
CREB3L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26174,688,367 - 174,816,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1726,698,619 - 26,827,174 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07129,833,446 - 129,960,145 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17142,326,266 - 142,452,438 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7142,331,759 - 142,452,438 (-)Ensemblpanpan1.1panPan2
CREB3L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11610,683,169 - 10,803,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1610,682,935 - 11,248,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1611,696,999 - 11,817,077 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01610,643,987 - 10,764,606 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1610,644,016 - 10,760,664 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11611,106,597 - 11,226,365 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01610,209,275 - 10,329,400 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01610,351,793 - 10,471,726 (+)NCBIUU_Cfam_GSD_1.0
Creb3l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511816,806,312 - 16,916,844 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365922,308,156 - 2,413,510 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365922,302,921 - 2,413,486 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CREB3L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1811,533,183 - 11,666,113 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11811,533,184 - 11,666,132 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21812,205,340 - 12,338,168 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CREB3L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121106,572,893 - 106,705,080 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21106,578,422 - 106,705,089 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660723,436,572 - 3,563,264 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Creb3l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476518,157,132 - 18,276,029 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476518,152,099 - 18,275,614 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Transcripts XM_013505001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01061517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBCQ01154997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCLAT00000001954   ⟹   ENSCLAP00000001910
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554945,045,272 - 5,089,121 (+)Ensembl
RefSeq Acc Id: XM_013505001   ⟹   XP_013360455
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554945,014,509 - 5,094,220 (+)NCBI
Sequence:
Protein RefSeqs XP_013360455 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001910
  ENSCLAP00000001910.1
RefSeq Acc Id: XP_013360455   ⟸   XM_013505001
- UniProtKB: A0A8C2UN88 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000001910   ⟸   ENSCLAT00000001954
bZIP



1 to 15 of 15 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000001408 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001954 ENTREZGENE
  ENSCLAT00000001954.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
NCBI Gene Creb3l2 ENTREZGENE
PANTHER CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A UniProtKB/TrEMBL
  PTHR46004:SF2 UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP SSF57959 UniProtKB/TrEMBL
UniProt A0A8C2UN88 ENTREZGENE, UniProtKB/TrEMBL
1 to 15 of 15 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Creb3l2  cAMP responsive element binding protein 3 like 2    cAMP responsive element binding protein 3-like 2  Symbol and/or name change 5135510 APPROVED