Akap10 (A-kinase anchoring protein 10) - Rat Genome Database

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Gene: Akap10 (A-kinase anchoring protein 10) Chinchilla lanigera
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Symbol: Akap10
Name: A-kinase anchoring protein 10
RGD ID: 8816520
Description: ENCODES a protein that exhibits protein kinase A binding (ortholog); INVOLVED IN protein localization (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Heart Block (ortholog); Meckel Syndrome 9 (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A kinase (PRKA) anchor protein 10; A-kinase anchor protein 10, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955467926,508 - 990,753 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955467919,207 - 990,753 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akap10Chinchillaautistic disorder  ISOAKAP10 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Akap10ChinchillaHeart Block  ISOAKAP10 (Homo sapiens)8554872ClinVar Annotator: match by term: Conduction disorder of the heartClinVarPMID:25741868
Akap10ChinchillaMeckel Syndrome 9  ISOAKAP10 (Homo sapiens)8554872ClinVar Annotator: match by term: Meckel syndrome and type 9ClinVarPMID:21493627
Akap10ChinchillaPotocki-Lupski syndrome  ISOAKAP10 (Homo sapiens)8554872ClinVar Annotator: match by term: Potocki-Lupski syndromeClinVarPMID:28837307
Akap10Chinchillasudden infant death syndrome  ISOAKAP10 (Homo sapiens)8554872ClinVar Annotator: match by term: SUDDEN INFANT DEATH SYNDROMEClinVarPMID:25741868


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akap10Chinchillaprotein localization acts_upstream_of_or_withinISOAkap10 (Mus musculus)9068941 PMID:11248059MGIPMID:11248059

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akap10Chinchillacytosol located_inISOAKAP10 (Homo sapiens)9068941 HPAGO_REF:0000052
Akap10Chinchillamitochondrion located_inISOAkap10 (Mus musculus)9068941 PMID:11248059MGIPMID:11248059
Akap10Chinchillamitochondrion located_inISOAKAP10 (Homo sapiens)9068941 PMID:34800366FlyBasePMID:34800366
Akap10Chinchillaplasma membrane located_inISOAKAP10 (Homo sapiens)9068941 HPAGO_REF:0000052
Akap10Chinchillaprotein-containing complex part_ofISOAKAP10 (Homo sapiens)9068941 PMID:25097019UniProtPMID:25097019

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akap10Chinchillaprotein kinase A (PKA) signaling pathway   ISOAKAP10 (Homo sapiens)9068941 RGDPMID:14715913 more ...

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
PMID:22301074   PMID:30032202  



Akap10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955467926,508 - 990,753 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955467919,207 - 990,753 (-)NCBIChiLan1.0ChiLan1.0
AKAP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381719,904,302 - 19,977,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1719,904,302 - 19,978,343 (-)EnsemblGRCh38hg38GRCh38
GRCh371719,807,615 - 19,881,141 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361719,749,341 - 19,821,721 (-)NCBINCBI36Build 36hg18NCBI36
Build 341719,749,343 - 19,821,721NCBI
Celera1717,222,124 - 17,295,198 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1719,186,622 - 19,259,887 (-)NCBIHuRef
CHM1_11719,816,578 - 19,889,916 (-)NCBICHM1_1
T2T-CHM13v2.01719,852,961 - 19,926,536 (-)NCBIT2T-CHM13v2.0
Akap10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,756,029 - 61,821,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1161,762,133 - 61,821,078 (-)EnsemblGRCm39 Ensembl
GRCm381161,865,203 - 61,930,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,871,307 - 61,930,252 (-)EnsemblGRCm38mm10GRCm38
MGSCv371161,684,809 - 61,743,728 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361161,687,502 - 61,746,421 (-)NCBIMGSCv36mm8
MGSCv361162,301,085 - 62,361,341 (-)NCBIMGSCv36mm8
Celera1168,653,621 - 68,654,049 (-)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.96NCBI
Akap10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,044,819 - 47,108,153 (-)NCBIGRCr8
mRatBN7.21046,545,371 - 46,608,730 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,551,532 - 46,608,769 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1051,248,531 - 51,311,754 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01050,739,062 - 50,802,283 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,242,473 - 46,305,700 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,150,902 - 48,210,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,150,902 - 48,210,074 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01047,937,683 - 48,001,356 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41048,031,107 - 48,087,922 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11048,075,066 - 48,101,518 (-)NCBI
Celera1045,798,800 - 45,855,285 (-)NCBICelera
Cytogenetic Map10q22NCBI
AKAP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,889,409 - 54,975,328 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,701,183 - 59,787,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,150,628 - 31,226,569 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,297,164 - 36,372,087 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,297,164 - 36,372,087 (+)Ensemblpanpan1.1panPan2
AKAP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1540,242,709 - 40,333,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl540,245,770 - 40,329,982 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha540,388,840 - 40,474,407 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0540,352,790 - 40,438,407 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl540,355,978 - 40,437,939 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1540,324,380 - 40,409,956 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0540,269,866 - 40,355,416 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,462,609 - 40,548,188 (+)NCBIUU_Cfam_GSD_1.0
Akap10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560258,792,417 - 58,865,444 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936821946,751 - 1,018,072 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936821946,761 - 1,019,488 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,732,123 - 59,789,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,732,317 - 59,782,422 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AKAP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11618,455,422 - 18,538,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1618,453,093 - 18,538,041 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660592,298,073 - 2,379,728 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Akap10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248496,221,551 - 6,300,264 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248496,221,655 - 6,306,497 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000013727   ⟹   ENSCLAP00000013573
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955467926,508 - 990,753 (-)Ensembl
RefSeq Acc Id: XM_005399292   ⟹   XP_005399349
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955467919,207 - 990,753 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013522190   ⟹   XP_013377644
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955467919,207 - 990,753 (-)NCBI
Sequence:
Protein RefSeqs XP_005399349 (Get FASTA)   NCBI Sequence Viewer  
  XP_013377644 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013573
  ENSCLAP00000013573.1
RefSeq Acc Id: XP_005399349   ⟸   XM_005399292
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YPE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013377644   ⟸   XM_013522190
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCLAP00000013573   ⟸   ENSCLAT00000013727
RGS



1 to 17 of 17 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000009378 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013727 ENTREZGENE
  ENSCLAT00000013727.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
InterPro AKAP10_AKB_dom UniProtKB/TrEMBL
  Cell_Polariz_PKAAnc UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
NCBI Gene Akap10 ENTREZGENE
PANTHER A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL UniProtKB/TrEMBL
  A-KINASE ANCHOR PROTEINS UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A8C2YPE9 ENTREZGENE, UniProtKB/TrEMBL
1 to 17 of 17 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Akap10  A-kinase anchoring protein 10    A kinase (PRKA) anchor protein 10  Symbol and/or name change 5135510 APPROVED