Tppp2 (tubulin polymerization promoting protein family member 2) - Rat Genome Database

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Gene: Tppp2 (tubulin polymerization promoting protein family member 2) Chinchilla lanigera
Analyze
Symbol: Tppp2
Name: tubulin polymerization promoting protein family member 2
RGD ID: 8786878
Description: ENCODES a protein that exhibits tubulin binding (ortholog); INVOLVED IN microtubule bundle formation (ortholog); regulation of flagellated sperm motility (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); purine nucleoside phosphorylase deficiency (ortholog); FOUND IN cytosol (ortholog); sperm flagellum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubulin polymerization-promoting protein family member 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,779,375 - 1,785,575 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,779,405 - 1,785,385 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
sperm flagellum  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tppp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,779,375 - 1,785,575 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,779,405 - 1,785,385 (+)NCBIChiLan1.0ChiLan1.0
TPPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381421,024,299 - 21,036,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1421,024,109 - 21,036,276 (+)EnsemblGRCh38hg38GRCh38
GRCh371421,498,376 - 21,500,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,568,296 - 20,570,167 (+)NCBINCBI36Build 36hg18NCBI36
Build 341420,568,511 - 20,570,166NCBI
Celera141,359,208 - 1,361,197 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,619,284 - 1,621,273 (+)NCBIHuRef
CHM1_11421,500,454 - 21,502,443 (+)NCBICHM1_1
T2T-CHM13v2.01415,221,665 - 15,233,755 (+)NCBIT2T-CHM13v2.0
Tppp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391452,155,887 - 52,158,161 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1452,155,882 - 52,158,157 (+)EnsemblGRCm39 Ensembl
GRCm381451,918,430 - 51,920,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,918,425 - 51,920,700 (+)EnsemblGRCm38mm10GRCm38
MGSCv371452,538,436 - 52,540,375 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361450,840,376 - 50,842,651 (+)NCBIMGSCv36mm8
Celera1448,904,044 - 48,905,975 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1426.72NCBI
Tppp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81527,087,457 - 27,090,869 (+)NCBIGRCr8
mRatBN7.21524,614,284 - 24,627,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,614,006 - 24,618,967 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,385,402 - 27,387,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,341,123 - 28,343,417 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,594,067 - 26,596,361 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,319,175 - 28,321,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,319,136 - 28,321,476 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01532,131,751 - 32,134,449 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,351,907 - 27,354,201 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1524,919,795 - 24,922,089 (+)NCBICelera
Cytogenetic Map15p14NCBI
TPPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,481,667 - 22,484,381 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,698,154 - 21,700,221 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,839,314 - 1,847,789 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,921,223 - 19,929,695 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,927,478 - 19,928,973 (+)Ensemblpanpan1.1panPan2
TPPP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,118,516 - 18,126,661 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,119,594 - 18,126,663 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,603,958 - 18,612,111 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,379,272 - 18,387,432 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,380,689 - 18,382,319 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11518,060,621 - 18,068,781 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,116,582 - 18,124,736 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,244,499 - 18,252,668 (+)NCBIUU_Cfam_GSD_1.0
Tppp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,320,929 - 32,323,163 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936880230,626 - 232,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936880230,626 - 232,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,105,215 - 78,110,405 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,106,126 - 78,108,570 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TPPP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,503,616 - 21,505,890 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,504,299 - 21,505,799 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605924,929,967 - 24,932,053 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tppp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,021,639 - 7,023,027 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,021,146 - 7,023,129 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002237   ⟹   ENSCLAP00000002191
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555501,779,375 - 1,785,575 (+)Ensembl
RefSeq Acc Id: XM_013508575   ⟹   XP_013364029
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555501,779,405 - 1,785,385 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013364029 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002191
  ENSCLAP00000002191.1
Reference Protein Sequences
RefSeq Acc Id: XP_013364029   ⟸   XM_013508575
- UniProtKB: A0A8C2UKE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002191   ⟸   ENSCLAT00000002237


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001582 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002237 ENTREZGENE
  ENSCLAT00000002237.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  P25-alpha UniProtKB/TrEMBL
NCBI Gene Tppp2 ENTREZGENE
PANTHER PTHR12932 UniProtKB/TrEMBL
  PTHR12932:SF21 UniProtKB/TrEMBL
Pfam p25-alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8C2UKE1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Tppp2  tubulin polymerization promoting protein family member 2    tubulin polymerization-promoting protein family member 2  Symbol and/or name change 5135510 APPROVED