Cndp2 (carnosine dipeptidase 2) - Rat Genome Database

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Gene: Cndp2 (carnosine dipeptidase 2) Chinchilla lanigera
Analyze
Symbol: Cndp2
Name: carnosine dipeptidase 2
RGD ID: 8783584
Description: ENCODES a protein that exhibits dipeptidase activity (ortholog); peptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH chromosome 18q deletion syndrome (ortholog); Diabetic Nephropathies (ortholog); intellectual disability (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CNDP dipeptidase 2 (metallopeptidase M20 family); cytosolic non-specific dipeptidase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540257,938,276 - 57,960,056 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540257,939,003 - 57,960,056 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cndp2Chinchillachromosome 18q deletion syndrome  ISOCNDP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Monosomy 18q and deletion 18qClinVarPMID:25741868 and PMID:31690835
Cndp2Chinchillaintellectual disability  ISOCNDP2 (Homo sapiens)8554872ClinVar Annotator: match by term: intellectual disabilitiesClinVarPMID:25741868
Cndp2Chinchillaintestinal volvulus  ISOCNDP2 (Homo sapiens)8554872ClinVar Annotator: match by term: INTESTINAL MALROTATION and FAMILIALClinVarPMID:25741868
Cndp2ChinchillaNeurodevelopmental Disorders  ISOCNDP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Cndp2Chinchillapulmonary valve stenosis  ISOCNDP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary valve stenosisClinVarPMID:25741868
Cndp2ChinchillaVolvulus Of Midgut  ISOCNDP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Volvulus of midgutClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cndp2ChinchillaDiabetic Nephropathies  ISOCNDP2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21573905
Cndp2Chinchillasteatotic liver disease  ISOCNDP2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25226513


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cndp2Chinchillaproteolysis acts_upstream_of_or_withinISOCndp2 (Mus musculus)9068941 PMID:1235912MGIPMID:1235912

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cndp2Chinchillacytosol located_inISOCNDP2 (Homo sapiens)9068941 HPAGO_REF:0000052
Cndp2Chinchillanucleoplasm located_inISOCNDP2 (Homo sapiens)9068941 HPAGO_REF:0000052

Molecular Function

  

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cndp2Chinchillahistidine metabolic pathway  ISOCNDP2 (Homo sapiens)9068941 SMPDBSMP:00044
Cndp2Chinchillahistidinemia pathway  ISOCNDP2 (Homo sapiens)9068941 SMPDBSMP:00191

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Cndp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540257,938,276 - 57,960,056 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540257,939,003 - 57,960,056 (+)NCBIChiLan1.0ChiLan1.0
CNDP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381874,496,363 - 74,523,454 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1874,495,816 - 74,523,454 (+)EnsemblGRCh38hg38GRCh38
GRCh371872,163,598 - 72,190,689 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361870,314,577 - 70,339,336 (+)NCBINCBI36Build 36hg18NCBI36
Build 341870,314,576 - 70,339,336NCBI
Celera1869,030,559 - 69,057,800 (+)NCBICelera
Cytogenetic Map18q22.3NCBI
HuRef1868,895,464 - 68,922,779 (+)NCBIHuRef
CHM1_11872,158,824 - 72,186,014 (+)NCBICHM1_1
T2T-CHM13v2.01874,723,735 - 74,750,816 (+)NCBIT2T-CHM13v2.0
Cndp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391884,685,590 - 84,703,827 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1884,685,590 - 84,703,827 (-)EnsemblGRCm39 Ensembl
GRCm381884,667,465 - 84,685,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1884,667,465 - 84,685,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371884,836,861 - 84,855,025 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361884,801,662 - 84,819,826 (-)NCBIMGSCv36mm8
Celera1885,734,462 - 85,752,580 (-)NCBICelera
Cytogenetic Map18E4NCBI
cM Map1857.53NCBI
Cndp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81880,314,799 - 80,331,900 (-)NCBIGRCr8
mRatBN7.21878,039,924 - 78,057,030 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1878,039,932 - 78,056,922 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1880,142,709 - 80,159,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01880,814,783 - 80,831,835 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01878,650,467 - 78,667,521 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01881,521,966 - 81,539,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1881,521,968 - 81,539,065 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01880,566,927 - 80,584,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41881,215,851 - 81,232,949 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11881,289,302 - 81,306,399 (-)NCBI
Celera1876,656,181 - 76,673,279 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
CNDP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21792,070,643 - 92,132,773 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11877,763,264 - 77,825,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01867,920,453 - 67,982,843 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11871,162,331 - 71,262,787 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1871,162,331 - 71,188,879 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl1871,199,916 - 71,250,847 (+)Ensemblpanpan1.1panPan2
CNDP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.114,914,739 - 4,931,700 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl14,914,737 - 4,929,449 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha15,922,186 - 5,939,148 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.014,725,237 - 4,742,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl14,725,241 - 4,742,200 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.114,764,150 - 4,781,110 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.014,717,626 - 4,734,583 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.014,888,578 - 4,905,557 (-)NCBIUU_Cfam_GSD_1.0
Cndp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494418,676,542 - 18,694,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366163,998,289 - 4,012,904 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366163,997,670 - 4,016,077 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNDP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1149,565,335 - 149,583,998 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11149,565,327 - 149,584,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21165,529,517 - 165,548,510 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNDP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1185,376,201 - 5,400,778 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl185,375,729 - 5,397,100 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606020,483,123 - 20,507,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cndp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248066,172,809 - 6,195,644 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248066,174,621 - 6,196,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000019354   ⟹   ENSCLAP00000019169
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540257,938,276 - 57,960,056 (+)Ensembl
RefSeq Acc Id: XM_005373079   ⟹   XP_005373136
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540257,939,003 - 57,960,056 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511436   ⟹   XP_013366890
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540257,940,165 - 57,960,056 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511441   ⟹   XP_013366895
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540257,939,791 - 57,960,056 (+)NCBI
Sequence:
Protein RefSeqs XP_005373136 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366890 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366895 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019169
  ENSCLAP00000019169.1
RefSeq Acc Id: XP_005373136   ⟸   XM_005373079
- UniProtKB: A0A8C2YS32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366895   ⟸   XM_013511441
- UniProtKB: A0A8C2YS32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366890   ⟸   XM_013511436
- UniProtKB: A0A8C2YS32 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000019169   ⟸   ENSCLAT00000019354
Peptidase M20 dimerisation



1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000013139 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019354 ENTREZGENE
  ENSCLAT00000019354.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.360 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro ArgE/DapE_CS UniProtKB/TrEMBL
  CNDP/DUG1 UniProtKB/TrEMBL
  Cyt/Met_Dipeptidase UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/TrEMBL
  Peptidase_M20_dimer UniProtKB/TrEMBL
NCBI Gene Cndp2 ENTREZGENE
PANTHER BETA-ALA-HIS DIPEPTIDASE UniProtKB/TrEMBL
  CYTOSOLIC NON-SPECIFIC DIPEPTIDASE UniProtKB/TrEMBL
Pfam M20_dimer UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/TrEMBL
PIRSF CNDP_dipeptidase UniProtKB/TrEMBL
PROSITE ARGE_DAPE_CPG2_2 UniProtKB/TrEMBL
Superfamily-SCOP Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A8C2YS32 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-28 Cndp2  carnosine dipeptidase 2    CNDP dipeptidase 2 (metallopeptidase M20 family)  Symbol and/or name change 5135510 APPROVED