Cndp2 (carnosine dipeptidase 2) - Rat Genome Database

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Gene: Cndp2 (carnosine dipeptidase 2) Heterocephalus glaber
Analyze
Symbol: Cndp2
Name: carnosine dipeptidase 2
RGD ID: 18910826
Description: ENCODES a protein that exhibits carboxypeptidase activity (inferred); dipeptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN proteolysis (ortholog); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH chromosome 18q deletion syndrome (ortholog); Diabetic Nephropathies (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CNDP dipeptidase 2 (metallopeptidase M20 family); cytosolic non-specific dipeptidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248066,172,809 - 6,195,644 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248066,174,621 - 6,196,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA,ISO)

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cndp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248066,172,809 - 6,195,644 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248066,174,621 - 6,196,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CNDP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381874,496,363 - 74,523,454 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1874,495,816 - 74,523,454 (+)EnsemblGRCh38hg38GRCh38
GRCh371872,163,598 - 72,190,689 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361870,314,577 - 70,339,336 (+)NCBINCBI36Build 36hg18NCBI36
Build 341870,314,576 - 70,339,336NCBI
Celera1869,030,559 - 69,057,800 (+)NCBICelera
Cytogenetic Map18q22.3NCBI
HuRef1868,895,464 - 68,922,779 (+)NCBIHuRef
CHM1_11872,158,824 - 72,186,014 (+)NCBICHM1_1
T2T-CHM13v2.01874,723,735 - 74,750,816 (+)NCBIT2T-CHM13v2.0
Cndp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391884,685,590 - 84,703,827 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1884,685,590 - 84,703,827 (-)EnsemblGRCm39 Ensembl
GRCm381884,667,465 - 84,685,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1884,667,465 - 84,685,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371884,836,861 - 84,855,025 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361884,801,662 - 84,819,826 (-)NCBIMGSCv36mm8
Celera1885,734,462 - 85,752,580 (-)NCBICelera
Cytogenetic Map18E4NCBI
cM Map1857.53NCBI
Cndp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81880,314,799 - 80,331,900 (-)NCBIGRCr8
mRatBN7.21878,039,924 - 78,057,030 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1878,039,932 - 78,056,922 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1880,142,709 - 80,159,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01880,814,783 - 80,831,835 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01878,650,467 - 78,667,521 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01881,521,966 - 81,539,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1881,521,968 - 81,539,065 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01880,566,927 - 80,584,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41881,215,851 - 81,232,949 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11881,289,302 - 81,306,399 (-)NCBI
Celera1876,656,181 - 76,673,279 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
Cndp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540257,938,276 - 57,960,056 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540257,939,003 - 57,960,056 (+)NCBIChiLan1.0ChiLan1.0
CNDP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21792,070,643 - 92,132,773 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11877,763,264 - 77,825,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01867,920,453 - 67,982,843 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11871,162,331 - 71,262,787 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1871,162,331 - 71,188,879 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl1871,199,916 - 71,250,847 (+)Ensemblpanpan1.1panPan2
CNDP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.114,914,739 - 4,931,700 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl14,914,737 - 4,929,449 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha15,922,186 - 5,939,148 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.014,725,237 - 4,742,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl14,725,241 - 4,742,200 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.114,764,150 - 4,781,110 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.014,717,626 - 4,734,583 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.014,888,578 - 4,905,557 (-)NCBIUU_Cfam_GSD_1.0
Cndp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494418,676,542 - 18,694,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366163,998,289 - 4,012,904 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366163,997,670 - 4,016,077 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNDP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1149,565,335 - 149,583,998 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11149,565,327 - 149,584,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21165,529,517 - 165,548,510 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNDP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1185,376,201 - 5,400,778 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl185,375,729 - 5,397,100 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606020,483,123 - 20,507,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000000490   ⟹   ENSHGLP00000000451
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248066,172,809 - 6,195,644 (-)Ensembl
RefSeq Acc Id: XM_004861952   ⟹   XP_004862009
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248066,174,621 - 6,194,097 (-)NCBI
RefSeq Acc Id: XM_004861953   ⟹   XP_004862010
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248066,174,621 - 6,196,039 (-)NCBI
RefSeq Acc Id: XM_004861954   ⟹   XP_004862011
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248066,174,621 - 6,195,626 (-)NCBI
RefSeq Acc Id: XM_021242155   ⟹   XP_021097814
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248066,174,621 - 6,193,174 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004862009 (Get FASTA)   NCBI Sequence Viewer  
  XP_004862010 (Get FASTA)   NCBI Sequence Viewer  
  XP_004862011 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097814 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000000451
  ENSHGLP00100012518
GenBank Protein JAN97104 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004862010   ⟸   XM_004861953
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J1L6 (UniProtKB/TrEMBL),   G5BAR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862011   ⟸   XM_004861954
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J1L6 (UniProtKB/TrEMBL),   G5BAR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862009   ⟸   XM_004861952
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J1L6 (UniProtKB/TrEMBL),   G5BAR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097814   ⟸   XM_021242155
- Peptide Label: isoform X2
- UniProtKB: G5BAR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000000451   ⟸   ENSHGLT00000000490


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000420 Ensembl, ENTREZGENE
  ENSHGLG00100009273 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000000490 ENTREZGENE
  ENSHGLT00100012662 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.360 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro ArgE/DapE_CS UniProtKB/TrEMBL
  CNDP/DUG1 UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/TrEMBL
  Peptidase_M20_dimer UniProtKB/TrEMBL
KEGG Report hgl:101709694 UniProtKB/TrEMBL
NCBI Gene Cndp2 ENTREZGENE
PANTHER BETA-ALA-HIS DIPEPTIDASE UniProtKB/TrEMBL
  CYTOSOLIC NON-SPECIFIC DIPEPTIDASE UniProtKB/TrEMBL
Pfam M20_dimer UniProtKB/TrEMBL
  Peptidase_M20 UniProtKB/TrEMBL
PIRSF CNDP_dipeptidase UniProtKB/TrEMBL
PROSITE ARGE_DAPE_CPG2_2 UniProtKB/TrEMBL
Superfamily-SCOP Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A0P6J1L6 ENTREZGENE, UniProtKB/TrEMBL
  G5BAR1 ENTREZGENE, UniProtKB/TrEMBL