Dgcr8 (DGCR8 microprocessor complex subunit) - Rat Genome Database

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Gene: Dgcr8 (DGCR8 microprocessor complex subunit) Chinchilla lanigera
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Symbol: Dgcr8
Name: DGCR8 microprocessor complex subunit
RGD ID: 8772816
Description: ENCODES a protein that exhibits double-stranded RNA binding (ortholog); heme binding (ortholog); identical protein binding (ortholog); INVOLVED IN DNA damage response (ortholog); positive regulation of pre-miRNA processing (ortholog); primary miRNA processing (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH alcohol dependence (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DGCR8, microprocessor complex subunit; microprocessor complex subunit DGCR8
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,998,565 - 18,030,831 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,998,565 - 18,034,247 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dgcr8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,998,565 - 18,030,831 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,998,565 - 18,034,247 (-)NCBIChiLan1.0ChiLan1.0
DGCR8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,080,241 - 20,111,872 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,080,221 - 20,111,877 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,067,764 - 20,099,395 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,447,834 - 18,479,400 (+)NCBINCBI36Build 36hg18NCBI36
Build 342218,442,387 - 18,473,952NCBI
Celera223,919,807 - 3,951,450 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,688,418 - 3,720,061 (+)NCBIHuRef
CHM1_12220,067,440 - 20,099,084 (+)NCBICHM1_1
T2T-CHM13v2.02220,459,152 - 20,490,922 (+)NCBIT2T-CHM13v2.0
Dgcr8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,071,812 - 18,107,115 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,071,812 - 18,107,110 (-)EnsemblGRCm39 Ensembl
GRCm381618,253,948 - 18,289,251 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,253,948 - 18,289,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv371618,254,057 - 18,289,261 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,167,527 - 18,202,731 (-)NCBIMGSCv36mm8
Celera1618,826,710 - 18,861,913 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.31NCBI
Dgcr8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,208,959 - 96,241,560 (+)NCBIGRCr8
mRatBN7.21182,704,673 - 82,737,251 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,704,729 - 82,737,242 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,433,115 - 91,465,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,094,345 - 84,126,856 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,147,858 - 83,180,371 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,852,682 - 86,885,233 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,852,711 - 86,885,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,946,649 - 89,979,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,698,795 - 84,731,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11184,739,438 - 84,770,066 (+)NCBI
Celera1181,481,738 - 81,514,247 (+)NCBICelera
Cytogenetic Map11q23NCBI
DGCR8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,707,454 - 29,738,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,254,342 - 32,285,490 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,841,041 - 2,872,325 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12218,518,789 - 18,544,740 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2218,518,783 - 18,544,740 (+)Ensemblpanpan1.1panPan2
DGCR8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.02630,628,666 - 30,665,068 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,628,671 - 30,665,046 (-)EnsemblROS_Cfam_1.0 Ensembl
Dgcr8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118138,725,854 - 138,776,754 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366194,020,815 - 4,030,465 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049366193,977,144 - 4,014,273 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,977,307 - 4,014,490 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DGCR8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,469,178 - 51,489,529 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,473,512 - 51,489,535 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21455,110,551 - 55,126,577 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DGCR8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,627,924 - 5,657,773 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,629,684 - 5,652,191 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660851,275,885 - 1,305,869 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dgcr8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747689,955 - 722,266 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747689,751 - 722,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000020500   ⟹   ENSCLAP00000020304
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544217,998,565 - 18,030,831 (-)Ensembl
RefSeq Acc Id: XM_005391742   ⟹   XP_005391799
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544217,998,565 - 18,030,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013517769   ⟹   XP_013373223
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544217,998,565 - 18,034,247 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391799 (Get FASTA)   NCBI Sequence Viewer  
  XP_013373223 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020304
  ENSCLAP00000020304.1
RefSeq Acc Id: XP_005391799   ⟸   XM_005391742
- UniProtKB: A0A8C2VVW1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373223   ⟸   XM_013517769
- UniProtKB: A0A8C2VVW1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000020304   ⟸   ENSCLAT00000020500
Protein Domains
DRBM   WW


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013910 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020500 ENTREZGENE
  ENSCLAT00000020500.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
  3.30.160.20 UniProtKB/TrEMBL
  3.30.160.590 UniProtKB/TrEMBL
InterPro DGCR8 UniProtKB/TrEMBL
  dsRBD_dom UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
NCBI Gene Dgcr8 ENTREZGENE
PANTHER MICROPROCESSOR COMPLEX SUBUNIT DGCR8 UniProtKB/TrEMBL
  PTHR13482 UniProtKB/TrEMBL
Pfam dsrm UniProtKB/TrEMBL
PROSITE DS_RBD UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART DSRM UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
UniProt A0A8C2VVW1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Dgcr8  DGCR8 microprocessor complex subunit    DGCR8, microprocessor complex subunit  Symbol and/or name change 5135510 APPROVED
2016-08-16 Dgcr8  DGCR8, microprocessor complex subunit    DGCR8 microprocessor complex subunit  Symbol and/or name change 5135510 APPROVED