Sgk3 (serum/glucocorticoid regulated kinase family member 3) - Rat Genome Database

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Gene: Sgk3 (serum/glucocorticoid regulated kinase family member 3) Chinchilla lanigera
Analyze
Symbol: Sgk3
Name: serum/glucocorticoid regulated kinase family member 3
RGD ID: 8770379
Description: ENCODES a protein that exhibits molecular adaptor activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (ortholog); ASSOCIATED WITH hypotrichosis (ortholog); prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase Sgk3; serum/glucocorticoid regulated kinase family, member 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544412,385,747 - 12,445,740 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544412,385,747 - 12,501,589 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Sgk3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544412,385,747 - 12,445,740 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544412,385,747 - 12,501,589 (-)NCBIChiLan1.0ChiLan1.0
SGK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38866,712,781 - 66,862,022 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl866,712,734 - 66,862,022 (+)EnsemblGRCh38hg38GRCh38
GRCh37867,625,016 - 67,774,257 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36867,787,445 - 67,936,811 (+)NCBINCBI36Build 36hg18NCBI36
Build 34867,850,015 - 67,936,809NCBI
Celera863,617,793 - 63,767,751 (+)NCBICelera
Cytogenetic Map8q13.1NCBI
HuRef863,116,616 - 63,266,844 (+)NCBIHuRef
CHM1_1867,679,569 - 67,829,231 (+)NCBICHM1_1
T2T-CHM13v2.0867,138,550 - 67,288,509 (+)NCBIT2T-CHM13v2.0
Sgk3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3919,868,355 - 9,972,795 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl19,868,332 - 9,971,070 (+)EnsemblGRCm39 Ensembl
GRCm3819,798,130 - 9,902,570 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl19,798,107 - 9,900,845 (+)EnsemblGRCm38mm10GRCm38
MGSCv3719,788,211 - 9,892,651 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3619,783,344 - 9,887,784 (+)NCBIMGSCv36mm8
Celera19,770,220 - 9,875,393 (+)NCBICelera
Cytogenetic Map1A2NCBI
cM Map12.08NCBI
Sgk3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,128,628 - 14,255,099 (-)NCBIGRCr8
mRatBN7.259,345,761 - 9,472,243 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,346,040 - 9,415,476 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx511,502,631 - 11,568,922 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0513,132,573 - 13,200,616 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0512,837,301 - 12,903,595 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.059,046,889 - 9,094,740 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl59,048,614 - 9,094,616 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0513,847,906 - 13,941,451 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera58,858,341 - 8,925,021 (-)NCBICelera
Cytogenetic Map5q11NCBI
SGK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2782,450,140 - 82,598,070 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1858,090,069 - 58,240,584 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0863,210,279 - 63,403,991 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1864,982,973 - 65,067,296 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl864,982,973 - 65,067,296 (+)Ensemblpanpan1.1panPan2
SGK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12916,236,197 - 16,418,225 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2916,274,352 - 16,415,598 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2916,661,140 - 16,731,156 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02916,355,030 - 16,498,290 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2916,355,068 - 16,506,875 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12916,457,800 - 16,527,880 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02916,557,222 - 16,627,460 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02916,813,736 - 16,884,005 (+)NCBIUU_Cfam_GSD_1.0
Sgk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530367,520,278 - 67,588,541 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364967,195,777 - 7,265,186 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364967,196,936 - 7,287,367 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Sgk3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474424,476,626 - 24,539,480 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474424,476,880 - 24,613,442 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000003302   ⟹   ENSCLAP00000003237
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544412,385,747 - 12,445,740 (-)Ensembl
RefSeq Acc Id: XM_005392140   ⟹   XP_005392197
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544412,385,747 - 12,445,980 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005392141   ⟹   XP_005392198
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544412,385,747 - 12,445,740 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005392143   ⟹   XP_005392200
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544412,385,747 - 12,501,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518177   ⟹   XP_013373631
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544412,385,747 - 12,501,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518178   ⟹   XP_013373632
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544412,385,747 - 12,501,589 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005392200   ⟸   XM_005392143
- UniProtKB: A0A8C2UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005392197   ⟸   XM_005392140
- UniProtKB: A0A8C2UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005392198   ⟸   XM_005392141
- UniProtKB: A0A8C2UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373632   ⟸   XM_013518178
- UniProtKB: A0A8C2UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373631   ⟸   XM_013518177
- UniProtKB: A0A8C2UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000003237   ⟸   ENSCLAT00000003302
Protein Domains
AGC-kinase C-terminal   Protein kinase   PX


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003302 ENTREZGENE
  ENSCLAT00000003302.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  CISK_PX UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  SGK3_dom UniProtKB/TrEMBL
NCBI Gene Sgk3 ENTREZGENE
PANTHER RIBOSOMAL PROTEIN S6 KINASE UniProtKB/TrEMBL
  SERUM/GLUCOCORTICOID REGULATED KINASE FAMILY MEMBER 3 UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  PS50195 UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A8C2UPI8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Sgk3  serum/glucocorticoid regulated kinase family member 3    serum/glucocorticoid regulated kinase family, member 3  Symbol and/or name change 5135510 APPROVED