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Gene: Uroc1 (urocanate hydratase 1) Chinchilla lanigera

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Symbol:

Uroc1

Name:

urocanate hydratase 1

RGD ID:

8759997

Description:

ENCODES a protein that exhibits urocanate hydratase activity (ortholog); INVOLVED IN L-histidine catabolic process (ortholog); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH alkaptonuria (ortholog); Ataxia (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

urocanate hydratase

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UROC1 (urocanate hydratase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Uroc1 (urocanase domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Uroc1 (urocanate hydratase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UROC1 (urocanate hydratase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UROC1 (urocanate hydratase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101964451 (urocanate hydratase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UROC1 (urocanate hydratase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UROC1 (urocanate hydratase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Uroc1 (urocanate hydratase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955421	21,732,262 - 21,765,772 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955421	21,734,910 - 21,765,754 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alkaptonuria (ISO)

Ataxia (ISO)

hepatocellular carcinoma (ISO)

intellectual disability (ISO)

Primary Lymphedema with Myelodysplasia (ISO)

urocanase deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

L-histidine catabolic process (ISO)

Cellular Component

cytosol (ISO)

Molecular Function

protein binding (ISO)

urocanate hydratase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

histidine metabolic pathway (ISO)

histidinemia pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Uroc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955421	21,732,262 - 21,765,772 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955421	21,734,910 - 21,765,754 (-)	NCBI	ChiLan1.0	ChiLan1.0

UROC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	126,481,166 - 126,517,773 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	126,481,166 - 126,517,773 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	126,200,009 - 126,236,616 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	127,682,814 - 127,719,284 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	127,682,821 - 127,719,292	NCBI
Celera	3	124,624,832 - 124,661,450 (-)	NCBI		Celera
Cytogenetic Map	3	q21.3	NCBI
HuRef	3	123,580,466 - 123,616,232 (-)	NCBI		HuRef
CHM1_1	3	126,163,023 - 126,199,631 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	129,213,641 - 129,250,072 (-)	NCBI		T2T-CHM13v2.0

Uroc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	90,310,221 - 90,341,533 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	90,310,266 - 90,341,533 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	90,333,239 - 90,364,551 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	90,333,284 - 90,364,551 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	90,283,283 - 90,314,545 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	90,298,810 - 90,330,055 (+)	NCBI		MGSCv36	mm8
Celera	6	92,226,993 - 92,258,298 (+)	NCBI		Celera
Cytogenetic Map	6	D1	NCBI
cM Map	6	40.15	NCBI

Uroc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	124,402,119 - 124,433,787 (+)	NCBI		GRCr8
mRatBN7.2	4	122,844,933 - 122,876,584 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	122,844,926 - 122,876,591 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	4	122,244,744 - 122,276,357 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	122,244,711 - 122,276,361 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	186,786,121 - 186,817,350 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	124,591,873 - 124,622,726 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	111,769,716 - 111,800,721 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

UROC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	124,405,735 - 124,454,247 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	124,416,615 - 124,451,933 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	123,530,644 - 123,569,337 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	130,845,588 - 130,882,167 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	130,846,775 - 130,882,119 (-)	Ensembl	panpan1.1		panPan2

UROC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	676,624 - 717,109 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	678,073 - 717,141 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	710,803 - 751,395 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	688,164 - 728,749 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	688,170 - 728,978 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	416,093 - 456,667 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	744,690 - 785,596 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	703,927 - 744,527 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101964451
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	19,090,631 - 19,103,805 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936898	584,157 - 600,305 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936898	583,802 - 600,305 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UROC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	53,590,776 - 53,637,713 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	53,592,763 - 53,634,214 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	58,628,304 - 58,665,410 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UROC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	54,497,373 - 54,536,295 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	54,499,487 - 54,535,862 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	111,758,893 - 111,795,753 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Uroc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624773	72,847 - 107,686 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624773	72,871 - 107,686 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005383834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013513807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013513808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01022117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01229852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000004772 ⟹ ENSCLAP00000004686

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955421	21,732,262 - 21,765,772 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000004773 ⟹ ENSCLAP00000004687

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955421	21,732,262 - 21,765,772 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000004774 ⟹ ENSCLAP00000004688

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955421	21,735,424 - 21,765,643 (-)	Ensembl

RefSeq Acc Id:

XM_005383834 ⟹ XP_005383891

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955421	21,734,910 - 21,765,754 (-)	NCBI

Sequence:

show sequence

GGCTGGAGGAGGTGGCCCTGGGGCTAGAGGTCCCCATCCGGCTGACTCCTGATTGTTCAGTGTC
CTCCCAGCCTCCCCACAGTGATGGTCTCCACCTCAAGCTCAGCAGCCATGTCCAGCCTCCAGAT
GCTGTGCTCCGGCCTGCCCTTGCGGCCCCTCCCGCAGAACCGGGGACGCTGGGCTGGGGTGCCG
CATGCCCCTGTCAGGACCCCTGGCCTCAGCCCTGTAGAAGAGCAGTTGGCCCTGAGGAATGCCC
TGCGCTACTTCCCACCTGATGTCCAGGAACTGCTGGCTCAGGAGTTTGCCCAGGAGCTGCGACT
CTATGGACACATCTACATGTACCGGTTCTGTCCCCACATCGAAATGAAGGCCTACCCAATCGAG
CAGTACCCCTGCCGGACAAGAGCTGCAGCAGCCATCATGCACATGATCATGAACAATCTGGACC
ATGCCGTAGCCCAGTTTCCCCAGGAGCTGGTGACCTATGGAGGAAATGGGCAGGTGTTCAGCAA
CTGGGCTCAGTTCTGGCTGACCATGCACTACTTGTCGAAGATGACTGAGGATCAGACCCTGGTC
ATGTACAGTGGACACCCGCTGGGCCTCTTCCCCAGCAGCCCTGGCGCCCCGAGGCTGGTCATCA
CCAATGGGATGGTCATTCCCAACTATTCCTCCAGGACAGAGTATGAGAAGCTGTTTGCCTTGGG
AGTCACAATGTACGGCCAGATGACAGCAGGCAGCTACTGCTACATCGGTCCCCAGGGAATCGTC
CACGGCACGGTGCTTACTGTGCTGAATGCTGCGCGCCGGTACCTGGGCATTGAGGACTTGGCTG
GGAAGGTCTTTGTCACCTCTGGGCTTGGCGGGATGAGCGGAGCTCAGGCCAAGGCTGCAGTCAT
CGTGGGGTGCATTGGCGTGATAGCAGAGGTTGATAAAGAAGCTCTTGTAAAACGCCGCCAGCAA
GGCTGGCTGATGGAAGTGACGGACAGCTTGGACCACTGCATTGAGAGACTCAGGAAAGCAAGGA
AAAAGAAGGAGGTGCTCAGTCTTGGTTACCATGGGAACATAGTAGATCTTTGGGAGCGCCTCGT
CCATGAATTGGACACCACAGGAGAGCTCTTGGTGGATCTCGGGTCAGACCAGACATCCTGCCAT
AACCCATTTAACGGTGGCTACTACCCTGTGCAGCTCAGCTTTGTTGAGGCCCAGCATCTCATGG
CTTCCAACCCACCTGCTTTCAAAGACCTAGTGCAAGAAAGCCTAAGGAGGCACATATCAGCCAT
CAACAGGCTGGCCAAAGAAAAATTCTTCTTCTGGGACTACGGCAATGCCTTCCTTTTGGAGGCA
CACAGAGCAGGAGCGGATGTGGCAAAGAAGGGTGCTCAGAAGACAGAATTCCGCTACCCGTCAT
ATGTCCAGCACATTATGGGGGACATATTCTCCCAGGGGTTTGGACCCTTCCGCTGGGTATGCAC
ATCGAGAGACCCCCAGGACCTGGCTGTCACAGACCAGCTGGCCACATCTGTGCTGGAGAAGGCC
ATTGCCGATGGAGTGAAGGCATCTGTGAAACTGCAGTATATGGACAACATCCGCTGGATCCGAG
AAGCCGCCAAGCATCAGCTGGTTGTGGGCTCTCAGGCACGTATCCTGTACTCAGACCAGAAGGG
CCGTGTGGCCATTGCCGTGGCCATTAACCAAGCCATCGCCAATGGAAATATCAAGGCCCCAGTG
GTTCTGAGCCGAGACCACCATGACGTAAGTGGCACTGACAGCCCCTTTCGAGAGACTTCCAACA
TATACGATGGCTCTGCCTTCTGTGCAGATATGGCTGTCCAGAACTTCGTGGGAGATGCCTGTCG
TGGAGCCACCTGGGTTGCGCTTCACAACGGAGGGGGCGTAGGCTGGGGTGAGGTGATCAATGGG
GGATTTGGCCTCGTGTTGGACGGATCCCCAGAGGCCGAGGATAAGGCCAGGATGATGCTCAGCT
GGGACGTCTCCAATGGTGTGGCCCGGCGCTGCTGGTCTGGGAACCCAAAGGCCTATGAGATCAT
CTGTCAGACGATGGAGGAGAACAGTGGCTTAGTAGTAACCCTCCCCCATGATGTGACAGACGAG
TGCATGATCCAGCGAGCCCTGCAGTCCTGAGAGGAATCCAGCAACCAGCTGCAGTCTTCCTTGT
TCCCCTTCCTCCCATGGCTCTCCTCGCCCTCCTCACCTCTACACACCTTCTCCTGCACTTCTGA
GCTTTACACACAAGCCCTCTGTGGCCCTCACAGCACTCTAGATGGGTCATATTGTACAGACAAG
CCCCAGAAAGGTGATGCCACTTGTCCATGACCATACTGCTTGACTAGGACCCCAAGGAGGGTAG
AGTATGTCTTGCTCAGAGCCAAGTCCTCAAGCCTCCTATGGGGTGGATGCCAACTTTGGGTGAC
TGCCATGAACTGGCCAACCTGGGCACCACCCAGTCTTTCCTAAGCCTCCCCAAGTTCTCTTTGG
GTTTTATCATATCACTCTGCCTCCTGTCTTCCTGTCTCCCAGCTCAGCGCTGCTCTGGTATCTG
CCCATTTATCTGTTCCTTGGCACCCTAGGATTGGGGATAAAAAGAAGGAGCCTAGGGAGGAAGA
TAAATAGGAAATAAAGGAAAAAAGTTTTAAAA

hide sequence

RefSeq Acc Id:

XM_013513807 ⟹ XP_013369261

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955421	21,734,910 - 21,765,753 (-)	NCBI

Sequence:

show sequence

GCTGGAGGAGGTGGCCCTGGGGCTAGAGGTCCCCATCCGGCTGACTCCTGATTGTTCAGTGTCC
TCCCAGCCTCCCCACAGTGATGGTCTCCACCTCAAGCTCAGCAGCCATGTCCAGCCTCCAGATG
CTGTGCTCCGGCCTGCCCTTGCGGCCCCTCCCGCAGAACCGGGGACGCTGGGCTGGGGTGCCGC
ATGCCCCTGTCAGGACCCCTGGCCTCAGCCCTGTAGAAGAGCAGTTGGCCCTGAGGAATGCCCT
GCGCTACTTCCCACCTGATGTCCAGGAACTGCTGGCTCAGGAGTTTGCCCAGGAGCTGCGACTC
TATGGACACATCTACATGTACCGGTTCTGTCCCCACATCGAAATGAAGGCCTACCCAATCGAGC
AGTACCCCTGCCGGACAAGAGCTGCAGCAGCCATCATGCACATGATCATGAACAATCTGGACCA
TGCCGTAGCCCAGTTCTGGCTGACCATGCACTACTTGTCGAAGATGACTGAGGATCAGACCCTG
GTCATGTACAGTGGACACCCGCTGGGCCTCTTCCCCAGCAGCCCTGGCGCCCCGAGGCTGGTCA
TCACCAATGGGATGGTCATTCCCAACTATTCCTCCAGGACAGAGTATGAGAAGCTGTTTGCCTT
GGGAGTCACAATGTACGGCCAGATGACAGCAGGCAGCTACTGCTACATCGGTCCCCAGGGAATC
GTCCACGGCACGGTGCTTACTGTGCTGAATGCTGCGCGCCGGTACCTGGGCATTGAGGACTTGG
CTGGGAAGGTCTTTGTCACCTCTGGGCTTGGCGGGATGAGCGGAGCTCAGGCCAAGGCTGCAGT
CATCGTGGGGTGCATTGGCGTGATAGCAGAGGTTGATAAAGAAGCTCTTGTAAAACGCCGCCAG
CAAGGCTGGCTGATGGAAGTGACGGACAGCTTGGACCACTGCATTGAGAGACTCAGGAAAGCAA
GGAAAAAGAAGGAGGTGCTCAGTCTTGGTTACCATGGGAACATAGTAGATCTTTGGGAGCGCCT
CGTCCATGAATTGGACACCACAGGAGAGCTCTTGGTGGATCTCGGGTCAGACCAGACATCCTGC
CATAACCCATTTAACGGTGGCTACTACCCTGTGCAGCTCAGCTTTGTTGAGGCCCAGCATCTCA
TGGCTTCCAACCCACCTGCTTTCAAAGACCTAGTGCAAGAAAGCCTAAGGAGGCACATATCAGC
CATCAACAGGCTGGCCAAAGAAAAATTCTTCTTCTGGGACTACGGCAATGCCTTCCTTTTGGAG
GCACACAGAGCAGGAGCGGATGTGGCAAAGAAGGGTGCTCAGAAGACAGAATTCCGCTACCCGT
CATATGTCCAGCACATTATGGGGGACATATTCTCCCAGGGGTTTGGACCCTTCCGCTGGGTATG
CACATCGAGAGACCCCCAGGACCTGGCTGTCACAGACCAGCTGGCCACATCTGTGCTGGAGAAG
GCCATTGCCGATGGAGTGAAGGCATCTGTGAAACTGCAGTATATGGACAACATCCGCTGGATCC
GAGAAGCCGCCAAGCATCAGCTGGTTGTGGGCTCTCAGGCACGTATCCTGTACTCAGACCAGAA
GGGCCGTGTGGCCATTGCCGTGGCCATTAACCAAGCCATCGCCAATGGAAATATCAAGGCCCCA
GTGGTTCTGAGCCGAGACCACCATGACGTAAGTGGCACTGACAGCCCCTTTCGAGAGACTTCCA
ACATATACGATGGCTCTGCCTTCTGTGCAGATATGGCTGTCCAGAACTTCGTGGGAGATGCCTG
TCGTGGAGCCACCTGGGTTGCGCTTCACAACGGAGGGGGCGTAGGCTGGGGTGAGGTGATCAAT
GGGGGATTTGGCCTCGTGTTGGACGGATCCCCAGAGGCCGAGGATAAGGCCAGGATGATGCTCA
GCTGGGACGTCTCCAATGGTGTGGCCCGGCGCTGCTGGTCTGGGAACCCAAAGGCCTATGAGAT
CATCTGTCAGACGATGGAGGAGAACAGTGGCTTAGTAGTAACCCTCCCCCATGATGTGACAGAC
GAGTGCATGATCCAGCGAGCCCTGCAGTCCTGAGAGGAATCCAGCAACCAGCTGCAGTCTTCCT
TGTTCCCCTTCCTCCCATGGCTCTCCTCGCCCTCCTCACCTCTACACACCTTCTCCTGCACTTC
TGAGCTTTACACACAAGCCCTCTGTGGCCCTCACAGCACTCTAGATGGGTCATATTGTACAGAC
AAGCCCCAGAAAGGTGATGCCACTTGTCCATGACCATACTGCTTGACTAGGACCCCAAGGAGGG
TAGAGTATGTCTTGCTCAGAGCCAAGTCCTCAAGCCTCCTATGGGGTGGATGCCAACTTTGGGT
GACTGCCATGAACTGGCCAACCTGGGCACCACCCAGTCTTTCCTAAGCCTCCCCAAGTTCTCTT
TGGGTTTTATCATATCACTCTGCCTCCTGTCTTCCTGTCTCCCAGCTCAGCGCTGCTCTGGTAT
CTGCCCATTTATCTGTTCCTTGGCACCCTAGGATTGGGGATAAAAAGAAGGAGCCTAGGGAGGA
AGATAAATAGGAAATAAAGGAAAAAAGTTTTAAAA

hide sequence

RefSeq Acc Id:

XM_013513808 ⟹ XP_013369262

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955421	21,734,910 - 21,765,753 (-)	NCBI

Sequence:

show sequence

GCTGGAGGAGGTGGCCCTGGGGCTAGAGGTCCCCATCCGGCTGACTCCTGATTGTTCAGTGTCC
TCCCAGCCTCCCCACAGTGATGGTCTCCACCTCAAGCTCAGCAGCCATGTCCAGCCTCCAGATG
CTGTGCTCCGGCCTGCCCTTGCGGCCCCTCCCGCAGAACCGGGGACGCTGGGCTGGGGTGCCGC
ATGCCCCTGTCAGGACCCCTGGCCTCAGCCCTGTAGAAGAGCAGTTGGCCCTGAGGAATGCCCT
GCGCTACTTCCCACCTGATGTCCAGGAACTGCTGGCTCAGGAGTTTGCCCAGGAGCTGCGACTC
TATGGACACATCTACATGTACCGGTTCTGTCCCCACATCGAAATGAAGGCCTACCCAATCGAGC
AGTACCCCTGCCGGACAAGAGCTGCAGCAGCCATCATGCACATGATCATGAACAATCTGGACCA
TGCCGTAGCCCAGGTCATTCCCAACTATTCCTCCAGGACAGAGTATGAGAAGCTGTTTGCCTTG
GGAGTCACAATGTACGGCCAGATGACAGCAGGCAGCTACTGCTACATCGGTCCCCAGGGAATCG
TCCACGGCACGGTGCTTACTGTGCTGAATGCTGCGCGCCGGTACCTGGGCATTGAGGACTTGGC
TGGGAAGGTCTTTGTCACCTCTGGGCTTGGCGGGATGAGCGGAGCTCAGGCCAAGGCTGCAGTC
ATCGTGGGGTGCATTGGCGTGATAGCAGAGGTTGATAAAGAAGCTCTTGTAAAACGCCGCCAGC
AAGGCTGGCTGATGGAAGTGACGGACAGCTTGGACCACTGCATTGAGAGACTCAGGAAAGCAAG
GAAAAAGAAGGAGGTGCTCAGTCTTGGTTACCATGGGAACATAGTAGATCTTTGGGAGCGCCTC
GTCCATGAATTGGACACCACAGGAGAGCTCTTGGTGGATCTCGGGTCAGACCAGACATCCTGCC
ATAACCCATTTAACGGTGGCTACTACCCTGTGCAGCTCAGCTTTGTTGAGGCCCAGCATCTCAT
GGCTTCCAACCCACCTGCTTTCAAAGACCTAGTGCAAGAAAGCCTAAGGAGGCACATATCAGCC
ATCAACAGGCTGGCCAAAGAAAAATTCTTCTTCTGGGACTACGGCAATGCCTTCCTTTTGGAGG
CACACAGAGCAGGAGCGGATGTGGCAAAGAAGGGTGCTCAGAAGACAGAATTCCGCTACCCGTC
ATATGTCCAGCACATTATGGGGGACATATTCTCCCAGGGGTTTGGACCCTTCCGCTGGGTATGC
ACATCGAGAGACCCCCAGGACCTGGCTGTCACAGACCAGCTGGCCACATCTGTGCTGGAGAAGG
CCATTGCCGATGGAGTGAAGGCATCTGTGAAACTGCAGTATATGGACAACATCCGCTGGATCCG
AGAAGCCGCCAAGCATCAGCTGGTTGTGGGCTCTCAGGCACGTATCCTGTACTCAGACCAGAAG
GGCCGTGTGGCCATTGCCGTGGCCATTAACCAAGCCATCGCCAATGGAAATATCAAGGCCCCAG
TGGTTCTGAGCCGAGACCACCATGACGTAAGTGGCACTGACAGCCCCTTTCGAGAGACTTCCAA
CATATACGATGGCTCTGCCTTCTGTGCAGATATGGCTGTCCAGAACTTCGTGGGAGATGCCTGT
CGTGGAGCCACCTGGGTTGCGCTTCACAACGGAGGGGGCGTAGGCTGGGGTGAGGTGATCAATG
GGGGATTTGGCCTCGTGTTGGACGGATCCCCAGAGGCCGAGGATAAGGCCAGGATGATGCTCAG
CTGGGACGTCTCCAATGGTGTGGCCCGGCGCTGCTGGTCTGGGAACCCAAAGGCCTATGAGATC
ATCTGTCAGACGATGGAGGAGAACAGTGGCTTAGTAGTAACCCTCCCCCATGATGTGACAGACG
AGTGCATGATCCAGCGAGCCCTGCAGTCCTGAGAGGAATCCAGCAACCAGCTGCAGTCTTCCTT
GTTCCCCTTCCTCCCATGGCTCTCCTCGCCCTCCTCACCTCTACACACCTTCTCCTGCACTTCT
GAGCTTTACACACAAGCCCTCTGTGGCCCTCACAGCACTCTAGATGGGTCATATTGTACAGACA
AGCCCCAGAAAGGTGATGCCACTTGTCCATGACCATACTGCTTGACTAGGACCCCAAGGAGGGT
AGAGTATGTCTTGCTCAGAGCCAAGTCCTCAAGCCTCCTATGGGGTGGATGCCAACTTTGGGTG
ACTGCCATGAACTGGCCAACCTGGGCACCACCCAGTCTTTCCTAAGCCTCCCCAAGTTCTCTTT
GGGTTTTATCATATCACTCTGCCTCCTGTCTTCCTGTCTCCCAGCTCAGCGCTGCTCTGGTATC
TGCCCATTTATCTGTTCCTTGGCACCCTAGGATTGGGGATAAAAAGAAGGAGCCTAGGGAGGAA
GATAAATAGGAAATAAAGGAAAAAAGTTTTAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005383891	(Get FASTA)	NCBI Sequence Viewer
	XP_013369261	(Get FASTA)	NCBI Sequence Viewer
	XP_013369262	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000004686
	ENSCLAP00000004686.1
	ENSCLAP00000004687
	ENSCLAP00000004687.1
	ENSCLAP00000004688.1

RefSeq Acc Id:	XP_005383891 ⟸ XM_005383834
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UWF0 (UniProtKB/TrEMBL), A0A8C2URB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVSTSSSAAMSSLQMLCSGLPLRPLPQNRGRWAGVPHAPVRTPGLSPVEEQLALRNALRYFPPD VQELLAQEFAQELRLYGHIYMYRFCPHIEMKAYPIEQYPCRTRAAAAIMHMIMNNLDHAVAQFP QELVTYGGNGQVFSNWAQFWLTMHYLSKMTEDQTLVMYSGHPLGLFPSSPGAPRLVITNGMVIP NYSSRTEYEKLFALGVTMYGQMTAGSYCYIGPQGIVHGTVLTVLNAARRYLGIEDLAGKVFVTS GLGGMSGAQAKAAVIVGCIGVIAEVDKEALVKRRQQGWLMEVTDSLDHCIERLRKARKKKEVLS LGYHGNIVDLWERLVHELDTTGELLVDLGSDQTSCHNPFNGGYYPVQLSFVEAQHLMASNPPAF KDLVQESLRRHISAINRLAKEKFFFWDYGNAFLLEAHRAGADVAKKGAQKTEFRYPSYVQHIMG DIFSQGFGPFRWVCTSRDPQDLAVTDQLATSVLEKAIADGVKASVKLQYMDNIRWIREAAKHQL VVGSQARILYSDQKGRVAIAVAINQAIANGNIKAPVVLSRDHHDVSGTDSPFRETSNIYDGSAF CADMAVQNFVGDACRGATWVALHNGGGVGWGEVINGGFGLVLDGSPEAEDKARMMLSWDVSNGV ARRCWSGNPKAYEIICQTMEENSGLVVTLPHDVTDECMIQRALQS hide sequence

RefSeq Acc Id:	XP_013369262 ⟸ XM_013513808
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C2URB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVSTSSSAAMSSLQMLCSGLPLRPLPQNRGRWAGVPHAPVRTPGLSPVEEQLALRNALRYFPPD VQELLAQEFAQELRLYGHIYMYRFCPHIEMKAYPIEQYPCRTRAAAAIMHMIMNNLDHAVAQVI PNYSSRTEYEKLFALGVTMYGQMTAGSYCYIGPQGIVHGTVLTVLNAARRYLGIEDLAGKVFVT SGLGGMSGAQAKAAVIVGCIGVIAEVDKEALVKRRQQGWLMEVTDSLDHCIERLRKARKKKEVL SLGYHGNIVDLWERLVHELDTTGELLVDLGSDQTSCHNPFNGGYYPVQLSFVEAQHLMASNPPA FKDLVQESLRRHISAINRLAKEKFFFWDYGNAFLLEAHRAGADVAKKGAQKTEFRYPSYVQHIM GDIFSQGFGPFRWVCTSRDPQDLAVTDQLATSVLEKAIADGVKASVKLQYMDNIRWIREAAKHQ LVVGSQARILYSDQKGRVAIAVAINQAIANGNIKAPVVLSRDHHDVSGTDSPFRETSNIYDGSA FCADMAVQNFVGDACRGATWVALHNGGGVGWGEVINGGFGLVLDGSPEAEDKARMMLSWDVSNG VARRCWSGNPKAYEIICQTMEENSGLVVTLPHDVTDECMIQRALQS hide sequence

RefSeq Acc Id:	XP_013369261 ⟸ XM_013513807
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2URA9 (UniProtKB/TrEMBL), A0A8C2URB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVSTSSSAAMSSLQMLCSGLPLRPLPQNRGRWAGVPHAPVRTPGLSPVEEQLALRNALRYFPPD VQELLAQEFAQELRLYGHIYMYRFCPHIEMKAYPIEQYPCRTRAAAAIMHMIMNNLDHAVAQFW LTMHYLSKMTEDQTLVMYSGHPLGLFPSSPGAPRLVITNGMVIPNYSSRTEYEKLFALGVTMYG QMTAGSYCYIGPQGIVHGTVLTVLNAARRYLGIEDLAGKVFVTSGLGGMSGAQAKAAVIVGCIG VIAEVDKEALVKRRQQGWLMEVTDSLDHCIERLRKARKKKEVLSLGYHGNIVDLWERLVHELDT TGELLVDLGSDQTSCHNPFNGGYYPVQLSFVEAQHLMASNPPAFKDLVQESLRRHISAINRLAK EKFFFWDYGNAFLLEAHRAGADVAKKGAQKTEFRYPSYVQHIMGDIFSQGFGPFRWVCTSRDPQ DLAVTDQLATSVLEKAIADGVKASVKLQYMDNIRWIREAAKHQLVVGSQARILYSDQKGRVAIA VAINQAIANGNIKAPVVLSRDHHDVSGTDSPFRETSNIYDGSAFCADMAVQNFVGDACRGATWV ALHNGGGVGWGEVINGGFGLVLDGSPEAEDKARMMLSWDVSNGVARRCWSGNPKAYEIICQTME ENSGLVVTLPHDVTDECMIQRALQS hide sequence

Ensembl Acc Id:

ENSCLAP00000004688 ⟸ ENSCLAT00000004774

Ensembl Acc Id:

ENSCLAP00000004686 ⟸ ENSCLAT00000004772

Ensembl Acc Id:

ENSCLAP00000004687 ⟸ ENSCLAT00000004773

Protein Domains

Urocanase C-terminal Urocanase N-terminal Urocanase Rossmann-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000003335	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000004772	ENTREZGENE
	ENSCLAT00000004772.1	UniProtKB/TrEMBL
	ENSCLAT00000004773	ENTREZGENE
	ENSCLAT00000004773.1	UniProtKB/TrEMBL
	ENSCLAT00000004774.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.10730	UniProtKB/TrEMBL
	Urocanase superfamily	UniProtKB/TrEMBL
InterPro	Urocanase	UniProtKB/TrEMBL
	Urocanase_C	UniProtKB/TrEMBL
	Urocanase_central_sf	UniProtKB/TrEMBL
	Urocanase_CS	UniProtKB/TrEMBL
	Urocanase_N	UniProtKB/TrEMBL
	Urocanase_Rossmann-like	UniProtKB/TrEMBL
	Urocanase_sf	UniProtKB/TrEMBL
NCBI Gene	Uroc1	ENTREZGENE
PANTHER	PTHR12216	UniProtKB/TrEMBL
	UROCANATE HYDRATASE	UniProtKB/TrEMBL
Pfam	Urocanase	UniProtKB/TrEMBL
	Urocanase_C	UniProtKB/TrEMBL
	Urocanase_N	UniProtKB/TrEMBL
PIRSF	Urocanate_hydrat	UniProtKB/TrEMBL
PROSITE	UROCANASE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF111326	UniProtKB/TrEMBL
UniProt	A0A8C2URA9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2URB1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2UWF0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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Imported Annotations - SMPDB