UROC1 (urocanate hydratase 1) - Rat Genome Database
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Gene: UROC1 (urocanate hydratase 1) Pan paniscus
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Symbol: UROC1
Name: urocanate hydratase 1
RGD ID: 11782841
Description: ENCODES a protein that exhibits urocanate hydratase activity (ortholog); INVOLVED IN histidine catabolic process (ortholog); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH Ataxia (ortholog); hepatocellular carcinoma (ortholog); intellectual disability (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: urocanate hydratase; urocanase domain containing 1; urocanate hydratase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13130,845,588 - 130,882,167 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3130,846,775 - 130,882,119 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03123,530,644 - 123,569,337 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
UROC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13130,845,588 - 130,882,167 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3130,846,775 - 130,882,119 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03123,530,644 - 123,569,337 (-)NCBIMhudiblu_PPA_v0panPan3
UROC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3126,481,166 - 126,517,773 (-)EnsemblGRCh38hg38GRCh38
GRCh383126,481,166 - 126,517,773 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373126,200,008 - 126,236,616 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363127,682,814 - 127,719,284 (-)NCBINCBI36hg18NCBI36
Build 343127,682,821 - 127,719,292NCBI
Celera3124,624,832 - 124,661,450 (-)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3123,580,466 - 123,616,232 (-)NCBIHuRef
CHM1_13126,163,023 - 126,199,631 (-)NCBICHM1_1
Uroc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,310,221 - 90,341,533 (+)NCBIGRCm39mm39
GRCm38690,333,239 - 90,364,551 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,333,284 - 90,364,551 (+)EnsemblGRCm38mm10GRCm38
MGSCv37690,283,283 - 90,314,545 (+)NCBIGRCm37mm9NCBIm37
MGSCv36690,298,810 - 90,330,055 (+)NCBImm8
Celera692,226,993 - 92,258,298 (+)NCBICelera
Cytogenetic Map6D1NCBI
Uroc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04122,244,744 - 122,276,357 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4122,244,711 - 122,276,361 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04186,786,121 - 186,817,350 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44124,591,873 - 124,622,726 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4111,769,716 - 111,800,721 (+)NCBICelera
Cytogenetic Map4q34NCBI
Uroc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,732,262 - 21,765,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542121,734,910 - 21,765,754 (-)NCBIChiLan1.0ChiLan1.0
UROC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl20678,073 - 717,141 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.120676,624 - 717,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Uroc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936898583,802 - 600,305 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UROC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,590,776 - 53,637,714 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,592,763 - 53,634,214 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2758,628,304 - 58,665,410 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UROC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl2254,499,487 - 54,535,862 (+)Ensembl
ChlSab1.12254,497,373 - 54,536,295 (+)NCBI
Uroc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477372,871 - 107,686 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000061700   ⟹   ENSPPAP00000038792
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3130,846,775 - 130,882,119 (-)Ensembl
RefSeq Acc Id: XM_014344353   ⟹   XP_014199839
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.13130,845,588 - 130,882,167 (-)NCBI
Mhudiblu_PPA_v03123,530,644 - 123,566,457 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034957287   ⟹   XP_034813178
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v03123,530,644 - 123,569,337 (-)NCBI
Protein Sequences
Protein RefSeqs XP_014199839 (Get FASTA)   NCBI Sequence Viewer  
  XP_034813178 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_014199839   ⟸   XM_014344353
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034813178   ⟸   XM_034957287
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000038792   ⟸   ENSPPAT00000061700
Protein Domains
Urocanase   Urocanase_C   Urocanase_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042107 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000038792 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061700 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10730 UniProtKB/TrEMBL
InterPro Urocanase UniProtKB/TrEMBL
  Urocanase_C UniProtKB/TrEMBL
  Urocanase_central_sf UniProtKB/TrEMBL
  Urocanase_CS UniProtKB/TrEMBL
  Urocanase_N UniProtKB/TrEMBL
  Urocanase_Rossmann-like UniProtKB/TrEMBL
  Urocanase_sf UniProtKB/TrEMBL
NCBI Gene UROC1 ENTREZGENE
PANTHER PTHR12216 UniProtKB/TrEMBL
Pfam Urocanase UniProtKB/TrEMBL
  Urocanase_C UniProtKB/TrEMBL
  Urocanase_N UniProtKB/TrEMBL
PROSITE UROCANASE UniProtKB/TrEMBL
Superfamily-SCOP SSF111326 UniProtKB/TrEMBL
UniProt A0A2R9CKV8_PANPA UniProtKB/TrEMBL