Bud23 (BUD23 rRNA methyltransferase and ribosome maturation factor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Bud23 (BUD23 rRNA methyltransferase and ribosome maturation factor) Chinchilla lanigera
Analyze
Symbol: Bud23
Name: BUD23 rRNA methyltransferase and ribosome maturation factor
RGD ID: 8752660
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); rRNA (guanine) methyltransferase activity (ortholog); INVOLVED IN positive regulation of rRNA processing (ortholog); rRNA (guanine-N7)-methylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); intestinal volvulus (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BUD23, rRNA methyltransferase and ribosome maturation factor; probable 18S rRNA (guanine-N(7))-methyltransferase; Wbscr22; Williams Beuren syndrome chromosome region 22; Williams-Beuren syndrome chromosome region 22
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,047,409 - 14,057,939 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,047,409 - 14,057,483 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bud23
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,047,409 - 14,057,939 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,047,409 - 14,057,483 (-)NCBIChiLan1.0ChiLan1.0
BUD23
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,683,597 - 73,698,212 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl773,683,597 - 73,698,212 (+)EnsemblGRCh38hg38GRCh38
GRCh37773,097,927 - 73,112,542 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,735,834 - 72,750,478 (+)NCBINCBI36Build 36hg18NCBI36
Build 34772,542,548 - 72,557,192NCBI
Celera768,576,112 - 68,590,746 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef768,980,309 - 68,994,966 (+)NCBIHuRef
CHM1_1773,243,634 - 73,258,288 (+)NCBICHM1_1
T2T-CHM13v2.0774,884,512 - 74,899,128 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,430,970 - 72,445,623 (+)NCBI
Bud23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,081,811 - 135,093,813 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,081,811 - 135,093,813 (-)EnsemblGRCm39 Ensembl
GRCm385135,052,957 - 135,064,959 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,052,957 - 135,064,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv375135,528,827 - 135,539,980 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365135,337,586 - 135,349,586 (-)NCBIMGSCv36mm8
Celera5132,063,286 - 132,074,439 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.97NCBI
Bud23
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,266,093 - 27,277,300 (+)NCBIGRCr8
mRatBN7.21221,629,551 - 21,640,758 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,629,536 - 21,640,751 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,769,812 - 22,781,449 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,382,129 - 23,393,766 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,450,784 - 22,461,993 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,669,626 - 24,680,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,669,449 - 24,680,818 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,669,896 - 26,681,103 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,724,688 - 22,735,895 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1223,392,836 - 23,404,043 (+)NCBICelera
Cytogenetic Map12q12NCBI
BUD23
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2691,201,923 - 91,216,615 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17139,466,554 - 139,481,234 (-)NCBINHGRI_mPanPan1
PanPan1.1780,836,518 - 80,851,501 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,836,518 - 80,851,497 (+)Ensemblpanpan1.1panPan2
BUD23
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,583,612 - 6,596,538 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,583,616 - 6,595,281 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha68,281,013 - 8,293,928 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.066,398,642 - 6,411,560 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,398,641 - 6,410,307 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,388,142 - 6,401,056 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,335,879 - 6,348,795 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,499,592 - 6,512,508 (-)NCBIUU_Cfam_GSD_1.0
Bud23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,127,809 - 131,138,719 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,897,432 - 2,908,802 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,897,884 - 2,908,758 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BUD23
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,960,092 - 10,973,082 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1310,960,037 - 10,973,084 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,656,154 - 10,669,253 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BUD23
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,368,950 - 9,382,951 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,368,726 - 9,382,925 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660707,119,984 - 7,134,024 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bud23
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,120,798 - 14,131,933 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474014,120,798 - 14,131,490 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000006887   ⟹   ENSCLAP00000006776
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545614,047,409 - 14,057,483 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000006888   ⟹   ENSCLAP00000006777
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545614,047,461 - 14,057,939 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000006889   ⟹   ENSCLAP00000006778
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545614,047,461 - 14,057,402 (-)Ensembl
RefSeq Acc Id: XM_005396771   ⟹   XP_005396828
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545614,047,409 - 14,057,483 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396828 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006776
  ENSCLAP00000006776.1
  ENSCLAP00000006777.1
  ENSCLAP00000006778.1
RefSeq Acc Id: XP_005396828   ⟸   XM_005396771
- UniProtKB: A0A8C2UWD4 (UniProtKB/TrEMBL),   A0A8C2UX74 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000006778   ⟸   ENSCLAT00000006889
Ensembl Acc Id: ENSCLAP00000006777   ⟸   ENSCLAT00000006888
Ensembl Acc Id: ENSCLAP00000006776   ⟸   ENSCLAT00000006887
Protein Domains
18S rRNA (guanine(1575)-N(7))-methyltransferase   Methyltransferase type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004776 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006887 ENTREZGENE
  ENSCLAT00000006887.1 UniProtKB/TrEMBL
  ENSCLAT00000006888.1 UniProtKB/TrEMBL
  ENSCLAT00000006889.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Bud23-like UniProtKB/TrEMBL
  Bud23_C UniProtKB/TrEMBL
  Methyltransf_11 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene Wbscr22 ENTREZGENE
PANTHER 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED UniProtKB/TrEMBL
  PTHR12734 UniProtKB/TrEMBL
Pfam Methyltransf_11 UniProtKB/TrEMBL
  WBS_methylT UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8C2UWD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UX74 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YL66_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-22 Bud23  BUD23 rRNA methyltransferase and ribosome maturation factor    BUD23, rRNA methyltransferase and ribosome maturation factor  Symbol and/or name change 5135510 APPROVED
2017-02-28 Bud23  BUD23, rRNA methyltransferase and ribosome maturation factor  Wbscr22  Williams-Beuren syndrome chromosome region 22  Symbol and/or name change 5135510 APPROVED
2016-08-03 Wbscr22  Williams-Beuren syndrome chromosome region 22    Williams Beuren syndrome chromosome region 22  Symbol and/or name change 5135510 APPROVED