Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)) Chinchilla lanigera
Analyze
Symbol: Entpd5
Name: ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
RGD ID: 8747976
Description: ENCODES a protein that exhibits ADP phosphatase activity (ortholog); CDP phosphatase activity (ortholog); GDP phosphatase activity (ortholog); INVOLVED IN 'de novo' post-translational protein folding (ortholog); protein N-linked glycosylation (ortholog); UDP catabolic process (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); pneumonia (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum lumen (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ectonucleoside triphosphate diphosphohydrolase 5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,421,749 - 1,441,829 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,407,812 - 1,441,829 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Entpd5Chinchillagenetic disease  ISOENTPD5 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:24763291 more ...
Entpd5Chinchillaintellectual disability  ISOENTPD5 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and mildClinVar 
Entpd5Chinchillapneumonia  ISOENTPD5 (Homo sapiens)8554872ClinVar Annotator: match by term: increased susceptibility to pneumoniaClinVar 
Entpd5Chinchillaprimary ciliary dyskinesia 16  ISOENTPD5 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary ciliary dyskinesia 16ClinVarPMID:21496787 and PMID:28492532
Entpd5Chinchillaprimary coenzyme Q10 deficiency 6  ISOENTPD5 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:21540551 more ...


Biological Process

  

Cellular Component

  

Imported Annotations - SMPDB

1 to 15 of 15 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Entpd5Chinchillaadenine phoshoribosyltransferase deficiency pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00535
Entpd5Chinchillaadenosine monophosphate deaminase deficiency pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00537
Entpd5Chinchillaadenylosuccinate lyase deficiency pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00167
Entpd5ChinchillaAICA-ribosuria pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00168
Entpd5Chinchillaazathioprine pharmacodynamics pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00427
Entpd5ChinchillaKelley-Seegmiller syndrome pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00365
Entpd5ChinchillaLesch-Nyhan syndrome pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00364
Entpd5Chinchillamercaptopurine pharmacodynamics pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00428
Entpd5Chinchillamolybdenum cofactor deficiency pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00203
Entpd5Chinchillapurine metabolic pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00050
Entpd5Chinchillapurine nucleoside phosphorylase deficiency pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00210
Entpd5Chinchillatioguanine pharmacodynamics pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00430
Entpd5Chinchillaxanthinuria type I pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00512
Entpd5Chinchillaxanthinuria pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00220
Entpd5Chinchillaxanthinuria type II pathway  ISOENTPD5 (Homo sapiens)9068941 SMPDBSMP:00513
1 to 15 of 15 rows

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:30032202  



Entpd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,421,749 - 1,441,829 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,407,812 - 1,441,829 (+)NCBIChiLan1.0ChiLan1.0
ENTPD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,955,329 - 74,019,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,958,010 - 74,019,399 (-)EnsemblGRCh38hg38GRCh38
GRCh371474,422,032 - 74,485,991 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,502,925 - 73,555,714 (-)NCBINCBI36Build 36hg18NCBI36
Build 341473,502,935 - 73,552,386NCBI
Celera1454,470,115 - 54,522,978 (-)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,600,020 - 54,652,679 (-)NCBIHuRef
CHM1_11474,372,748 - 74,425,579 (-)NCBICHM1_1
T2T-CHM13v2.01468,162,983 - 68,226,953 (-)NCBIT2T-CHM13v2.0
Entpd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,420,649 - 84,455,803 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,420,631 - 84,455,803 (-)EnsemblGRCm39 Ensembl
GRCm381284,373,875 - 84,409,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,373,857 - 84,409,029 (-)EnsemblGRCm38mm10GRCm38
MGSCv371285,714,807 - 85,749,979 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361285,263,605 - 85,298,777 (-)NCBIMGSCv36mm8
Celera1285,828,883 - 85,864,542 (-)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.18NCBI
Entpd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,750,210 - 109,786,376 (-)NCBIGRCr8
mRatBN7.26104,019,095 - 104,055,311 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6104,019,185 - 104,055,530 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,183,850 - 104,213,756 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,482,934 - 104,512,840 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,852,516 - 103,882,424 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06108,087,677 - 108,123,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,087,418 - 108,120,579 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,422,586 - 117,458,720 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,439,822 - 108,469,756 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,443,290 - 108,473,213 (-)NCBI
Celera6101,850,366 - 101,880,006 (-)NCBICelera
Cytogenetic Map6q31NCBI
ENTPD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21575,053,109 - 75,109,253 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11474,269,629 - 74,325,714 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,522,428 - 54,578,501 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,376,684 - 73,418,946 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,376,684 - 73,410,468 (-)Ensemblpanpan1.1panPan2
ENTPD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,193,463 - 47,245,865 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl847,196,439 - 47,229,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,877,776 - 46,930,168 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,422,519 - 47,473,081 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl847,414,872 - 47,464,118 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1847,090,154 - 47,142,547 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0847,108,174 - 47,160,585 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,498,539 - 47,550,882 (-)NCBIUU_Cfam_GSD_1.0
Entpd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,789,021 - 28,828,004 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364883,237,772 - 3,279,947 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364883,241,004 - 3,280,360 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENTPD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,266,824 - 97,306,981 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,270,698 - 97,316,578 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27103,024,868 - 103,070,633 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ENTPD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,176,137 - 51,234,575 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2451,181,859 - 51,231,078 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605339,386,948 - 39,459,247 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Entpd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473427,570,815 - 27,610,766 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473427,568,738 - 27,610,046 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000004901   ⟹   ENSCLAP00000004810
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555231,421,749 - 1,441,829 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000004902   ⟹   ENSCLAP00000004811
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555231,421,992 - 1,441,445 (+)Ensembl
RefSeq Acc Id: XM_013507129   ⟹   XP_013362583
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,407,812 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507130   ⟹   XP_013362584
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,421,450 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507131   ⟹   XP_013362585
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,407,959 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507132   ⟹   XP_013362586
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,407,829 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507133   ⟹   XP_013362587
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,407,952 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507134   ⟹   XP_013362588
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,407,829 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507135   ⟹   XP_013362589
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,421,749 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507136   ⟹   XP_013362590
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,417,676 - 1,441,829 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507137   ⟹   XP_013362591
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555231,417,675 - 1,441,829 (+)NCBI
Sequence:
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: XP_013362583   ⟸   XM_013507129
- UniProtKB: A0A8C2YK84 (UniProtKB/TrEMBL),   A0A8C2YK94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362586   ⟸   XM_013507132
- UniProtKB: A0A8C2YK84 (UniProtKB/TrEMBL),   A0A8C2YK94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362588   ⟸   XM_013507134
- UniProtKB: A0A8C2YK84 (UniProtKB/TrEMBL),   A0A8C2YK94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362587   ⟸   XM_013507133
- UniProtKB: A0A8C2YK84 (UniProtKB/TrEMBL),   A0A8C2YK94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362585   ⟸   XM_013507131
- UniProtKB: A0A8C2YK84 (UniProtKB/TrEMBL),   A0A8C2YK94 (UniProtKB/TrEMBL)
- Sequence:



1 to 15 of 15 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000003418 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004901 ENTREZGENE
  ENSCLAT00000004901.1 UniProtKB/TrEMBL
  ENSCLAT00000004902 ENTREZGENE
  ENSCLAT00000004902.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.40 UniProtKB/TrEMBL
  Exopolyphosphatase. Domain 2 UniProtKB/TrEMBL
InterPro GDA1_CD39_NTPase UniProtKB/TrEMBL
NCBI Gene Entpd5 ENTREZGENE
PANTHER ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 5 UniProtKB/TrEMBL
  PTHR11782 UniProtKB/TrEMBL
Pfam GDA1_CD39 UniProtKB/TrEMBL
PROSITE GDA1_CD39_NTPASE UniProtKB/TrEMBL
UniProt A0A8C2YK84 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YK94 ENTREZGENE, UniProtKB/TrEMBL
1 to 15 of 15 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-05 Entpd5  ectonucleoside triphosphate diphosphohydrolase 5 (inactive)    ectonucleoside triphosphate diphosphohydrolase 5  Symbol and/or name change 5135510 APPROVED