Fbxl3 (F-box and leucine rich repeat protein 3) - Rat Genome Database

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Gene: Fbxl3 (F-box and leucine rich repeat protein 3) Chinchilla lanigera
Analyze
Symbol: Fbxl3
Name: F-box and leucine rich repeat protein 3
RGD ID: 8715715
Description: ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN entrainment of circadian clock by photoperiod (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein destabilization (ortholog); ASSOCIATED WITH chromosome 13q14 deletion syndrome (ortholog); INTELLECTUAL DEVELOPMENTAL DISORDER WITH SHORT STATURE, FACIAL ANOMALIES, AND SPEECH DEFECTS (ortholog); neuronal ceroid lipofuscinosis (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box and leucine-rich repeat protein 3; F-box/LRR-repeat protein 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540430,215,108 - 30,229,798 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540430,215,140 - 30,229,798 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbxl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540430,215,108 - 30,229,798 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540430,215,140 - 30,229,798 (+)NCBIChiLan1.0ChiLan1.0
FBXL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381377,005,260 - 77,027,159 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1376,992,598 - 77,027,195 (-)EnsemblGRCh38hg38GRCh38
GRCh371377,579,395 - 77,601,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361376,477,397 - 76,499,258 (-)NCBINCBI36Build 36hg18NCBI36
Build 341376,477,396 - 76,499,258NCBI
Celera1358,477,376 - 58,499,318 (-)NCBICelera
Cytogenetic Map13q22.3NCBI
HuRef1358,277,088 - 58,299,043 (-)NCBIHuRef
CHM1_11377,547,295 - 77,569,223 (-)NCBICHM1_1
T2T-CHM13v2.01376,222,648 - 76,250,801 (-)NCBIT2T-CHM13v2.0
Fbxl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914103,318,470 - 103,337,016 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14103,317,675 - 103,337,002 (-)EnsemblGRCm39 Ensembl
GRCm3814103,080,239 - 103,099,566 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14103,080,239 - 103,099,566 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714103,479,456 - 103,498,726 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614101,967,535 - 101,986,017 (-)NCBIMGSCv36mm8
Celera14101,708,112 - 101,723,414 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1451.73NCBI
Fbxl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81586,321,504 - 86,341,387 (-)NCBIGRCr8
mRatBN7.21579,906,795 - 79,926,678 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1579,906,795 - 79,927,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1583,885,188 - 83,905,079 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01585,008,227 - 85,028,119 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01581,935,852 - 81,955,744 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01593,647,307 - 93,667,395 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1593,647,310 - 93,667,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01597,135,100 - 97,155,065 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41587,093,141 - 87,113,003 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11587,110,759 - 87,128,783 (-)NCBI
Celera1579,046,955 - 79,066,741 (-)NCBICelera
Cytogenetic Map15q21NCBI
FBXL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21478,574,434 - 78,596,390 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11377,170,580 - 77,192,331 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01358,219,260 - 58,244,780 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11377,266,496 - 77,283,651 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1377,266,496 - 77,283,651 (-)Ensemblpanpan1.1panPan2
FBXL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12230,579,598 - 30,598,879 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2230,581,474 - 30,598,886 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2230,440,696 - 30,459,977 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02230,891,689 - 30,910,990 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2230,891,692 - 30,911,121 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12230,559,157 - 30,578,437 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02230,597,466 - 30,616,743 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02230,666,969 - 30,686,249 (-)NCBIUU_Cfam_GSD_1.0
Fbxl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945128,841,836 - 128,863,274 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365114,258,548 - 4,283,285 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365114,259,066 - 4,280,501 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1149,131,665 - 49,151,009 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11149,131,663 - 49,151,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21153,769,579 - 53,788,895 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1356,089,147 - 56,111,472 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl356,088,938 - 56,105,977 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604612,297,829 - 12,320,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475123,374,702 - 23,398,727 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475123,374,622 - 23,391,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000003609   ⟹   ENSCLAP00000003535
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540430,215,108 - 30,229,798 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000003610   ⟹   ENSCLAP00000003536
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540430,215,140 - 30,229,206 (+)Ensembl
RefSeq Acc Id: XM_005374164   ⟹   XP_005374221
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540430,215,140 - 30,229,798 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005374221 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000003535
  ENSCLAP00000003535.1
  ENSCLAP00000003536.1
RefSeq Acc Id: XP_005374221   ⟸   XM_005374164
- UniProtKB: A0A8C2UNK4 (UniProtKB/TrEMBL),   A0A8C2UNL0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000003536   ⟸   ENSCLAT00000003610
Ensembl Acc Id: ENSCLAP00000003535   ⟸   ENSCLAT00000003609
Protein Domains
F-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003609 ENTREZGENE
  ENSCLAT00000003609.1 UniProtKB/TrEMBL
  ENSCLAT00000003610.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Fbxl3 ENTREZGENE
PANTHER ES1 PROTEIN HOMOLOG, MITOCHONDRIAL UniProtKB/TrEMBL
  F-BOX DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A8C2UNK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UNL0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Fbxl3  F-box and leucine rich repeat protein 3    F-box and leucine-rich repeat protein 3  Symbol and/or name change 5135510 APPROVED