FBXL3 (F-box and leucine rich repeat protein 3) - Rat Genome Database

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Gene: FBXL3 (F-box and leucine rich repeat protein 3) Homo sapiens
Analyze
Symbol: FBXL3
Name: F-box and leucine rich repeat protein 3
RGD ID: 1343078
HGNC Page HGNC:13599
Description: Contributes to ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and regulation of circadian rhythm. Located in nuclear body. Part of SCF ubiquitin ligase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: F-box and leucine-rich repeat protein 3; F-box and leucine-rich repeat protein 3A; F-box protein Fbl3a; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; FBL3; FBL3A; FBXL3A; IDDSFAS
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381377,005,260 - 77,027,159 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1376,992,598 - 77,027,195 (-)EnsemblGRCh38hg38GRCh38
GRCh371377,579,395 - 77,601,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361376,477,397 - 76,499,258 (-)NCBINCBI36Build 36hg18NCBI36
Build 341376,477,396 - 76,499,258NCBI
Celera1358,477,376 - 58,499,318 (-)NCBICelera
Cytogenetic Map13q22.3NCBI
HuRef1358,277,088 - 58,299,043 (-)NCBIHuRef
CHM1_11377,547,295 - 77,569,223 (-)NCBICHM1_1
T2T-CHM13v2.01376,222,648 - 76,250,801 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,IEA,ISS,TAS)
nuclear body  (IDA)
nucleus  (IBA,IEA,ISS)
SCF ubiquitin ligase complex  (IBA,IDA)
ubiquitin ligase complex  (NAS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10531035   PMID:10531037   PMID:10828603   PMID:10945468   PMID:12477932   PMID:15489334   PMID:16344560   PMID:17207965   PMID:17463251   PMID:19028597   PMID:20360068   PMID:21873635  
PMID:22268729   PMID:22939624   PMID:22975506   PMID:23453757   PMID:23503662   PMID:23616524   PMID:24085301   PMID:25158072   PMID:25756610   PMID:26186194   PMID:26243628   PMID:27529127  
PMID:27565346   PMID:27840026   PMID:28514442   PMID:28614300   PMID:28749470   PMID:29103612   PMID:30481285   PMID:30594330   PMID:30596474   PMID:31155351   PMID:32296183   PMID:32350066  
PMID:32937135   PMID:33961781   PMID:33962073  


Genomics

Comparative Map Data
FBXL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381377,005,260 - 77,027,159 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1376,992,598 - 77,027,195 (-)EnsemblGRCh38hg38GRCh38
GRCh371377,579,395 - 77,601,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361376,477,397 - 76,499,258 (-)NCBINCBI36Build 36hg18NCBI36
Build 341376,477,396 - 76,499,258NCBI
Celera1358,477,376 - 58,499,318 (-)NCBICelera
Cytogenetic Map13q22.3NCBI
HuRef1358,277,088 - 58,299,043 (-)NCBIHuRef
CHM1_11377,547,295 - 77,569,223 (-)NCBICHM1_1
T2T-CHM13v2.01376,222,648 - 76,250,801 (-)NCBIT2T-CHM13v2.0
Fbxl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914103,318,470 - 103,337,016 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14103,317,675 - 103,337,002 (-)EnsemblGRCm39 Ensembl
GRCm3814103,080,239 - 103,099,566 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14103,080,239 - 103,099,566 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714103,479,456 - 103,498,726 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614101,967,535 - 101,986,017 (-)NCBIMGSCv36mm8
Celera14101,708,112 - 101,723,414 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1451.73NCBI
Fbxl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81586,321,504 - 86,341,387 (-)NCBIGRCr8
mRatBN7.21579,906,795 - 79,926,678 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1579,906,795 - 79,927,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1583,885,188 - 83,905,079 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01585,008,227 - 85,028,119 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01581,935,852 - 81,955,744 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01593,647,307 - 93,667,395 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1593,647,310 - 93,667,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01597,135,100 - 97,155,065 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41587,093,141 - 87,113,003 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11587,110,759 - 87,128,783 (-)NCBI
Celera1579,046,955 - 79,066,741 (-)NCBICelera
Cytogenetic Map15q21NCBI
Fbxl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540430,215,108 - 30,229,798 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540430,215,140 - 30,229,798 (+)NCBIChiLan1.0ChiLan1.0
FBXL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21478,574,434 - 78,596,390 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11377,170,580 - 77,192,331 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01358,219,260 - 58,244,780 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11377,266,496 - 77,283,651 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1377,266,496 - 77,283,651 (-)Ensemblpanpan1.1panPan2
FBXL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12230,579,598 - 30,598,879 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2230,581,474 - 30,598,886 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2230,440,696 - 30,459,977 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02230,891,689 - 30,910,990 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2230,891,692 - 30,911,121 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12230,559,157 - 30,578,437 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02230,597,466 - 30,616,743 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02230,666,969 - 30,686,249 (-)NCBIUU_Cfam_GSD_1.0
Fbxl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945128,841,836 - 128,863,274 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365114,258,548 - 4,283,285 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365114,259,066 - 4,280,501 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1149,131,665 - 49,151,009 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11149,131,663 - 49,151,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21153,769,579 - 53,788,895 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1356,089,147 - 56,111,472 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl356,088,938 - 56,105,977 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604612,297,829 - 12,320,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475123,374,702 - 23,398,727 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475123,374,622 - 23,391,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FBXL3
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh37/hg19 13q11-34(chr13:19053605-115108528)x3 copy number gain See cases [RCV001353184] Chr13:19053605..115108528 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.3-31.3(chr13:31363472-90575292)x3 copy number gain See cases [RCV000050293] Chr13:31363472..90575292 [GRCh38]
Chr13:31937609..91227546 [GRCh37]
Chr13:30835609..90025547 [NCBI36]
Chr13:13q12.3-31.3		 pathogenic
GRCh38/hg38 13q14.12-31.3(chr13:44967523-92738168)x1 copy number loss See cases [RCV000050891] Chr13:44967523..92738168 [GRCh38]
Chr13:45541658..93390421 [GRCh37]
Chr13:44439658..92188422 [NCBI36]
Chr13:13q14.12-31.3		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3 copy number gain See cases [RCV000053726] Chr13:18946182..114304628 [GRCh38]
Chr13:19520322..115070103 [GRCh37]
Chr13:18418322..114088205 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000053731] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q12.3-31.1(chr13:30318913-83610426)x3 copy number gain See cases [RCV000053737] Chr13:30318913..83610426 [GRCh38]
Chr13:30893050..84184561 [GRCh37]
Chr13:29791050..83082562 [NCBI36]
Chr13:13q12.3-31.1		 pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3 copy number gain See cases [RCV000053719] Chr13:18565048..114327173 [GRCh38]
Chr13:19139188..115085141 [GRCh37]
Chr13:18037188..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3 copy number gain See cases [RCV000053723] Chr13:18850545..114327173 [GRCh38]
Chr13:19296527..115085141 [GRCh37]
Chr13:18194527..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q13.2-34(chr13:33528097-114327173)x3 copy number gain See cases [RCV000053759] Chr13:33528097..114327173 [GRCh38]
Chr13:34102234..115085141 [GRCh37]
Chr13:33000234..114110750 [NCBI36]
Chr13:13q13.2-34		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:43219125-114327314)x3 copy number gain See cases [RCV000053762] Chr13:43219125..114327314 [GRCh38]
Chr13:43793261..115085141 [GRCh37]
Chr13:42691261..114110891 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:44164751-114327173)x3 copy number gain See cases [RCV000053764] Chr13:44164751..114327173 [GRCh38]
Chr13:44738887..115085141 [GRCh37]
Chr13:43636887..114110750 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q14.12-34(chr13:44733046-114327173)x3 copy number gain See cases [RCV000053767] Chr13:44733046..114327173 [GRCh38]
Chr13:45307182..115085141 [GRCh37]
Chr13:44205182..114110750 [NCBI36]
Chr13:13q14.12-34		 pathogenic
GRCh38/hg38 13q21.33-31.1(chr13:71509212-82146085)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053768]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053768]|See cases [RCV000053768] Chr13:71509212..82146085 [GRCh38]
Chr13:72083344..82720220 [GRCh37]
Chr13:70981345..81618221 [NCBI36]
Chr13:13q21.33-31.1		 pathogenic
GRCh38/hg38 13q22.1-34(chr13:74345951-114327314)x3 copy number gain See cases [RCV000053770] Chr13:74345951..114327314 [GRCh38]
Chr13:74920088..115085141 [GRCh37]
Chr13:73818089..114110891 [NCBI36]
Chr13:13q22.1-34		 pathogenic
GRCh38/hg38 13q14.11-31.1(chr13:41288493-85137552)x3 copy number gain See cases [RCV000133944] Chr13:41288493..85137552 [GRCh38]
Chr13:41862629..85711687 [GRCh37]
Chr13:40760629..84609688 [NCBI36]
Chr13:13q14.11-31.1		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3 copy number gain See cases [RCV000134104] Chr13:19833130..114298614 [GRCh38]
Chr13:20407270..115064089 [GRCh37]
Chr13:19305270..114082191 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q21.32-31.2(chr13:66320998-87855429)x1 copy number loss See cases [RCV000134874] Chr13:66320998..87855429 [GRCh38]
Chr13:66895130..88507684 [GRCh37]
Chr13:65793131..87305685 [NCBI36]
Chr13:13q21.32-31.2		 pathogenic
GRCh38/hg38 13q21.2-31.1(chr13:60536344-84553188)x1 copy number loss See cases [RCV000134951] Chr13:60536344..84553188 [GRCh38]
Chr13:61110478..85127323 [GRCh37]
Chr13:60008479..84025324 [NCBI36]
Chr13:13q21.2-31.1		 pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1 copy number loss See cases [RCV000135610] Chr13:18445862..114327173 [GRCh38]
Chr13:19020001..115085141 [GRCh37]
Chr13:10098739..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q14.11-31.1(chr13:41143820-85137552)x1 copy number loss See cases [RCV000136526] Chr13:41143820..85137552 [GRCh38]
Chr13:41717956..85711687 [GRCh37]
Chr13:40615956..84609688 [NCBI36]
Chr13:13q14.11-31.1		 pathogenic
GRCh38/hg38 13q14.2-31.1(chr13:47117587-84300935)x1 copy number loss See cases [RCV000136647] Chr13:47117587..84300935 [GRCh38]
Chr13:47691722..84875070 [GRCh37]
Chr13:46589723..83773071 [NCBI36]
Chr13:13q14.2-31.1		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:40942298-114340331)x1 copy number loss See cases [RCV000137893] Chr13:40942298..114340331 [GRCh38]
Chr13:41516434..115085141 [GRCh37]
Chr13:40414434..114123908 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q13.1-31.1(chr13:32531486-86757044)x3 copy number gain See cases [RCV000138339] Chr13:32531486..86757044 [GRCh38]
Chr13:33105623..87409299 [GRCh37]
Chr13:32003623..86207300 [NCBI36]
Chr13:13q13.1-31.1		 pathogenic
GRCh38/hg38 13q21.33-31.1(chr13:72681540-79638468)x1 copy number loss See cases [RCV000138575] Chr13:72681540..79638468 [GRCh38]
Chr13:73255678..80212603 [GRCh37]
Chr13:72153679..79110604 [NCBI36]
Chr13:13q21.33-31.1		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3 copy number gain See cases [RCV000139078] Chr13:19833130..114327106 [GRCh38]
Chr13:20407270..115085141 [GRCh37]
Chr13:19305270..114110683 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3 copy number gain See cases [RCV000140004] Chr13:18456040..114340285 [GRCh38]
Chr13:19030180..115105760 [GRCh37]
Chr13:17928180..114123862 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q22.2-31.1(chr13:76530209-78531570)x1 copy number loss See cases [RCV000141902] Chr13:76530209..78531570 [GRCh38]
Chr13:77104344..79105705 [GRCh37]
Chr13:76002345..78003706 [NCBI36]
Chr13:13q22.2-31.1		 pathogenic|uncertain significance
GRCh38/hg38 13q21.31-31.1(chr13:63713365-79638415)x1 copy number loss See cases [RCV000141460] Chr13:63713365..79638415 [GRCh38]
Chr13:64287498..80212550 [GRCh37]
Chr13:63185499..79110551 [NCBI36]
Chr13:13q21.31-31.1		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3 copy number gain See cases [RCV000142924] Chr13:19671934..114340331 [GRCh38]
Chr13:20246074..115085141 [GRCh37]
Chr13:19144074..114123908 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3 copy number gain See cases [RCV000143462] Chr13:18862146..114342258 [GRCh38]
Chr13:19436286..115107733 [GRCh37]
Chr13:18334286..114125835 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.3-31.3(chr13:31363472-90575292)x3 copy number gain See cases [RCV000148244] Chr13:31363472..90575292 [GRCh38]
Chr13:31937609..91227546 [GRCh37]
Chr13:30835609..90025547 [NCBI36]
Chr13:13q12.3-31.3		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000148126] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q21.33-31.2(chr13:72013791-88021559)x1 copy number loss See cases [RCV000240205] Chr13:72013791..88021559 [GRCh37]
Chr13:13q21.33-31.2		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3 copy number gain See cases [RCV000240150] Chr13:19571503..115092569 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q22.1-31.3(chr13:74459395-93481294)x1 copy number loss See cases [RCV000598789] Chr13:74459395..93481294 [GRCh37]
Chr13:13q22.1-31.3		 pathogenic
GRCh37/hg19 13q14.3-33.3(chr13:53551300-109850651)x1 copy number loss See cases [RCV000449272] Chr13:53551300..109850651 [GRCh37]
Chr13:13q14.3-33.3		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733)x3 copy number gain See cases [RCV000449118] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510) copy number gain See cases [RCV000449142] Chr13:19571503..115092510 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q22.3-31.1(chr13:77455170-81099829)x1 copy number loss See cases [RCV000447604] Chr13:77455170..81099829 [GRCh37]
Chr13:13q22.3-31.1		 pathogenic
GRCh37/hg19 13q14.11-31.3(chr13:42457841-91796698)x1 copy number loss See cases [RCV000446747] Chr13:42457841..91796698 [GRCh37]
Chr13:13q14.11-31.3		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain See cases [RCV000445886] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.1-34(chr13:56431743-115107733) copy number gain See cases [RCV000510722] Chr13:56431743..115107733 [GRCh37]
Chr13:13q21.1-34		 pathogenic
GRCh37/hg19 13q21.33-31.1(chr13:72174742-82221361)x1 copy number loss See cases [RCV000448053] Chr13:72174742..82221361 [GRCh37]
Chr13:13q21.33-31.1		 pathogenic
GRCh37/hg19 13q21.2-31.1(chr13:61686543-83302092)x1 copy number loss See cases [RCV000448229] Chr13:61686543..83302092 [GRCh37]
Chr13:13q21.2-31.1		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733) copy number gain See cases [RCV000510405] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.33-34(chr13:71871468-115107733)x4 copy number gain See cases [RCV000510281] Chr13:71871468..115107733 [GRCh37]
Chr13:13q21.33-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3 copy number gain See cases [RCV000511880] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
NM_012158.4(FBXL3):c.776T>C (p.Val259Ala) single nucleotide variant Inborn genetic diseases [RCV003300135] Chr13:77007656 [GRCh38]
Chr13:77581791 [GRCh37]
Chr13:13q22.3		 uncertain significance
GRCh37/hg19 13q14.3-32.1(chr13:53932358-96586363)x3 copy number gain See cases [RCV000512571] Chr13:53932358..96586363 [GRCh37]
Chr13:13q14.3-32.1		 pathogenic
GRCh37/hg19 13q22.2-31.3(chr13:76942604-90660121)x1 copy number loss not provided [RCV000683568] Chr13:76942604..90660121 [GRCh37]
Chr13:13q22.2-31.3		 pathogenic
NC_000013.11:g.46968080_87381985del40413906 deletion Chromosome 13q14 deletion syndrome [RCV000721955] Chr13:46968080..87381985 [GRCh38]
Chr13:13q14.2-31.2		 pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3 copy number gain not provided [RCV000738115] Chr13:19058717..115103529 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3 copy number gain not provided [RCV000750643] Chr13:19031237..115107157 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.1-31.3(chr13:57058434-94684615)x1 copy number loss not provided [RCV000750731] Chr13:57058434..94684615 [GRCh37]
Chr13:13q21.1-31.3		 pathogenic
NM_012158.4(FBXL3):c.445C>T (p.Arg149Ter) single nucleotide variant Intellectual disability, short stature, facial anomalies, and joint dislocations [RCV000767371] Chr13:77018626 [GRCh38]
Chr13:77592761 [GRCh37]
Chr13:13q22.3		 pathogenic
NM_012158.4(FBXL3):c.1072T>C (p.Cys358Arg) single nucleotide variant Intellectual disability, short stature, facial anomalies, and joint dislocations [RCV000767373] Chr13:77007360 [GRCh38]
Chr13:77581495 [GRCh37]
Chr13:13q22.3		 pathogenic
NM_012158.4(FBXL3):c.884del (p.Leu295fs) deletion Intellectual disability, short stature, facial anomalies, and joint dislocations [RCV000767372] Chr13:77007548 [GRCh38]
Chr13:77581683 [GRCh37]
Chr13:13q22.3		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV000849129] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61775567-115107733)x3 copy number gain not provided [RCV000848025] Chr13:61775567..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
NM_012158.4(FBXL3):c.473C>T (p.Ser158Phe) single nucleotide variant Inborn genetic diseases [RCV003271552] Chr13:77015579 [GRCh38]
Chr13:77589714 [GRCh37]
Chr13:13q22.3		 uncertain significance
NM_012158.4(FBXL3):c.472-10T>G single nucleotide variant Intellectual disability, short stature, facial anomalies, and joint dislocations [RCV001702031] Chr13:77015590 [GRCh38]
Chr13:77589725 [GRCh37]
Chr13:13q22.3		 benign
GRCh37/hg19 13q14.3-34(chr13:53262013-115107733)x1 copy number loss not provided [RCV001006567] Chr13:53262013..115107733 [GRCh37]
Chr13:13q14.3-34		 pathogenic
GRCh37/hg19 13q14.3-31.3(chr13:51512603-91631111)x1 copy number loss not provided [RCV001006564] Chr13:51512603..91631111 [GRCh37]
Chr13:13q14.3-31.3		 pathogenic
GRCh37/hg19 13q21.33-31.1(chr13:71502357-86571730)x1 copy number loss not provided [RCV001006577] Chr13:71502357..86571730 [GRCh37]
Chr13:13q21.33-31.1		 pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878) copy number gain Complete trisomy 13 syndrome [RCV002280659] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34		 pathogenic
NC_000013.10:g.(?_77566087)_(78492734_?)del deletion Neuronal ceroid lipofuscinosis [RCV001387711]|not provided [RCV003120596] Chr13:77566087..78492734 [GRCh37]
Chr13:13q22.3		 pathogenic|no classifications from unflagged records
GRCh37/hg19 13p13-q34(chr13:1-115169878)x3 copy number gain See cases [RCV001780076] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34		 pathogenic
NM_012158.4(FBXL3):c.751C>T (p.Arg251Ter) single nucleotide variant Intellectual disability, short stature, facial anomalies, and joint dislocations [RCV001806231] Chr13:77007681 [GRCh38]
Chr13:77581816 [GRCh37]
Chr13:13q22.3		 pathogenic
GRCh37/hg19 13q14.11-33.3(chr13:42504540-108206269)x3 copy number gain not provided [RCV001829235] Chr13:42504540..108206269 [GRCh37]
Chr13:13q14.11-33.3		 pathogenic
GRCh37/hg19 13q21.1-31.2(chr13:59574760-89410027)x1 copy number loss not provided [RCV001834426] Chr13:59574760..89410027 [GRCh37]
Chr13:13q21.1-31.2		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-114981726) copy number gain not specified [RCV002053035] Chr13:19436286..114981726 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q14.11-31.3(chr13:42457841-91796698) copy number loss not specified [RCV002053057] Chr13:42457841..91796698 [GRCh37]
Chr13:13q14.11-31.3		 pathogenic
GRCh37/hg19 13q13.3-31.1(chr13:36376204-80681753) copy number loss not specified [RCV002053052] Chr13:36376204..80681753 [GRCh37]
Chr13:13q13.3-31.1		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733) copy number gain not specified [RCV002053063] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q22.2-31.2(chr13:75574661-87784831) copy number loss not specified [RCV002053070] Chr13:75574661..87784831 [GRCh37]
Chr13:13q22.2-31.2		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733) copy number gain not specified [RCV002053036] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.2-31.1(chr13:61686543-83302092) copy number loss not specified [RCV002053064] Chr13:61686543..83302092 [GRCh37]
Chr13:13q21.2-31.1		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV001834436] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
NC_000013.10:g.(?_77566087)_(78492734_?)dup duplication not provided [RCV001930270] Chr13:77566087..78492734 [GRCh37]
Chr13:13q22.3		 uncertain significance
GRCh37/hg19 13q11-34(chr13:19253848-115108937)x3 copy number gain not provided [RCV002291540] Chr13:19253848..115108937 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q22.1-34(chr13:75268539-115107733)x3 copy number gain not provided [RCV002472537] Chr13:75268539..115107733 [GRCh37]
Chr13:13q22.1-34		 pathogenic
GRCh37/hg19 13q22.1-22.3(chr13:73600015-77624907)x1 copy number loss not provided [RCV002475822] Chr13:73600015..77624907 [GRCh37]
Chr13:13q22.1-22.3		 uncertain significance
NM_012158.4(FBXL3):c.446G>A (p.Arg149Gln) single nucleotide variant Inborn genetic diseases [RCV002910683] Chr13:77018625 [GRCh38]
Chr13:77592760 [GRCh37]
Chr13:13q22.3		 uncertain significance
NM_012158.4(FBXL3):c.1057C>T (p.Arg353Cys) single nucleotide variant Inborn genetic diseases [RCV002893021] Chr13:77007375 [GRCh38]
Chr13:77581510 [GRCh37]
Chr13:13q22.3		 uncertain significance
NM_012158.4(FBXL3):c.291G>T (p.Glu97Asp) single nucleotide variant Inborn genetic diseases [RCV002712350] Chr13:77021570 [GRCh38]
Chr13:77595705 [GRCh37]
Chr13:13q22.3		 uncertain significance
NM_012158.4(FBXL3):c.434T>C (p.Ile145Thr) single nucleotide variant Inborn genetic diseases [RCV002674137] Chr13:77018637 [GRCh38]
Chr13:77592772 [GRCh37]
Chr13:13q22.3		 uncertain significance
GRCh37/hg19 13q22.2-22.3(chr13:76441389-78303365)x3 copy number gain See cases [RCV003445447] Chr13:76441389..78303365 [GRCh37]
Chr13:13q22.2-22.3		 uncertain significance
GRCh37/hg19 13q21.33-33.1(chr13:73132193-104595598)x1 copy number loss not provided [RCV003483190] Chr13:73132193..104595598 [GRCh37]
Chr13:13q21.33-33.1		 pathogenic
GRCh37/hg19 13q22.1-34(chr13:73488238-115107733)x3 copy number gain not provided [RCV003484901] Chr13:73488238..115107733 [GRCh37]
Chr13:13q22.1-34		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61534068-115107733)x3 copy number gain not provided [RCV003484899] Chr13:61534068..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
NM_012158.4(FBXL3):c.387T>C (p.Asp129=) single nucleotide variant not provided [RCV003390377] Chr13:77018684 [GRCh38]
Chr13:77592819 [GRCh37]
Chr13:13q22.3		 likely benign
NM_012158.4(FBXL3):c.438A>C (p.Ser146=) single nucleotide variant not provided [RCV003393346] Chr13:77018633 [GRCh38]
Chr13:77592768 [GRCh37]
Chr13:13q22.3		 likely benign
GRCh37/hg19 13q14.2-32.2(chr13:49547974-98214905)x1 copy number loss not specified [RCV003987008] Chr13:49547974..98214905 [GRCh37]
Chr13:13q14.2-32.2		 pathogenic
GRCh37/hg19 13q21.1-31.3(chr13:56450978-93582180)x1 copy number loss not specified [RCV003987013] Chr13:56450978..93582180 [GRCh37]
Chr13:13q21.1-31.3		 pathogenic
GRCh37/hg19 13q21.31-33.1(chr13:64825656-103641349)x1 copy number loss not specified [RCV003987009] Chr13:64825656..103641349 [GRCh37]
Chr13:13q21.31-33.1		 pathogenic
NM_012158.4(FBXL3):c.1096C>T (p.Leu366=) single nucleotide variant FBXL3-related condition [RCV003921937] Chr13:77007336 [GRCh38]
Chr13:77581471 [GRCh37]
Chr13:13q22.3		 benign
NM_012158.4(FBXL3):c.644-9dup duplication FBXL3-related condition [RCV003932321] Chr13:77007796..77007797 [GRCh38]
Chr13:77581931..77581932 [GRCh37]
Chr13:13q22.3		 likely benign
NM_012158.4(FBXL3):c.644-9del deletion FBXL3-related condition [RCV003959240] Chr13:77007797 [GRCh38]
Chr13:77581932 [GRCh37]
Chr13:13q22.3		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1189
Count of miRNA genes:778
Interacting mature miRNAs:880
Transcripts:ENST00000355619, ENST00000417323, ENST00000470210, ENST00000472949, ENST00000477982, ENST00000485797
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-19996  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371377,579,536 - 77,579,660UniSTSGRCh37
Build 361376,477,537 - 76,477,661RGDNCBI36
Celera1358,477,523 - 58,477,647RGD
Cytogenetic Map13q22UniSTS
HuRef1358,277,235 - 58,277,359UniSTS
GeneMap99-GB4 RH Map13220.22UniSTS
Whitehead-RH Map13194.3UniSTS
RH119624  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371377,602,726 - 77,603,034UniSTSGRCh37
Build 361376,500,727 - 76,501,035RGDNCBI36
Celera1358,500,713 - 58,501,021RGD
Cytogenetic Map13q22UniSTS
HuRef1358,300,438 - 58,300,746UniSTS
TNG Radiation Hybrid Map1327401.0UniSTS
A006Y41  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371377,580,595 - 77,580,694UniSTSGRCh37
Build 361376,478,596 - 76,478,695RGDNCBI36
Celera1358,478,582 - 58,478,681RGD
Cytogenetic Map13q22UniSTS
HuRef1358,278,294 - 58,278,393UniSTS
GeneMap99-GB4 RH Map13220.75UniSTS
RH131875  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371377,581,320 - 77,581,522UniSTSGRCh37
Build 361376,479,321 - 76,479,523RGDNCBI36
Celera1358,479,307 - 58,479,509RGD
HuRef1358,279,019 - 58,279,221UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2396 2270 1526 461 1492 304 4150 1895 3307 353 1416 1575 170 1203 2714 4
Low 43 718 200 163 456 161 207 302 427 65 44 38 5 1 1 74 2 2
Below cutoff 3 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005266336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005266337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017020538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC001226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF126028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF129532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI133484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA119701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000355619   ⟹   ENSP00000347834
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1377,005,260 - 77,027,159 (-)Ensembl
RefSeq Acc Id: ENST00000417323   ⟹   ENSP00000412183
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1377,007,565 - 77,027,195 (-)Ensembl
RefSeq Acc Id: ENST00000470210
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1377,015,165 - 77,018,744 (-)Ensembl
RefSeq Acc Id: ENST00000472949
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1377,015,511 - 77,027,085 (-)Ensembl
RefSeq Acc Id: ENST00000477982
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1376,999,137 - 77,018,686 (-)Ensembl
RefSeq Acc Id: ENST00000485797
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1376,992,598 - 77,015,581 (-)Ensembl
RefSeq Acc Id: NM_012158   ⟹   NP_036290
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381377,005,260 - 77,027,159 (-)NCBI
GRCh371377,579,389 - 77,601,331 (-)RGD
Build 361376,477,397 - 76,499,258 (-)NCBI Archive
Celera1358,477,376 - 58,499,318 (-)RGD
HuRef1358,277,088 - 58,299,043 (-)RGD
CHM1_11377,547,295 - 77,569,223 (-)NCBI
T2T-CHM13v2.01376,228,900 - 76,250,796 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005266336   ⟹   XP_005266393
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381377,005,260 - 77,027,159 (-)NCBI
GRCh371377,579,389 - 77,601,331 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054374423   ⟹   XP_054230398
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01376,228,900 - 76,250,801 (-)NCBI
RefSeq Acc Id: XM_054374424   ⟹   XP_054230399
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01376,222,648 - 76,250,796 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_036290   ⟸   NM_012158
- UniProtKB: B2RB04 (UniProtKB/Swiss-Prot),   Q9P122 (UniProtKB/Swiss-Prot),   Q9UKT7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005266393   ⟸   XM_005266336
- Peptide Label: isoform X1
- UniProtKB: B2RB04 (UniProtKB/Swiss-Prot),   Q9P122 (UniProtKB/Swiss-Prot),   Q9UKT7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000412183   ⟸   ENST00000417323
RefSeq Acc Id: ENSP00000347834   ⟸   ENST00000355619
RefSeq Acc Id: XP_054230399   ⟸   XM_054374424
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054230398   ⟸   XM_054374423
- Peptide Label: isoform X1
- UniProtKB: Q9P122 (UniProtKB/Swiss-Prot),   Q9UKT7 (UniProtKB/Swiss-Prot),   B2RB04 (UniProtKB/Swiss-Prot)
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UKT7-F1-model_v2 AlphaFold Q9UKT7 1-428 view protein structure

Promoters
RGD ID:6790873
Promoter ID:HG_KWN:18144
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000045312,   OTTHUMT00000045313,   OTTHUMT00000045314
Position:
Human AssemblyChrPosition (strand)Source
Build 361376,499,134 - 76,499,634 (-)MPROMDB
RGD ID:7226615
Promoter ID:EPDNEW_H19052
Type:initiation region
Name:FBXL3_1
Description:F-box and leucine rich repeat protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381377,027,159 - 77,027,219EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13599 AgrOrtholog
COSMIC FBXL3 COSMIC
Ensembl Genes ENSG00000005812 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000355619 ENTREZGENE
  ENST00000355619.10 UniProtKB/Swiss-Prot
  ENST00000417323.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000005812 GTEx
HGNC ID HGNC:13599 ENTREZGENE
Human Proteome Map FBXL3 Human Proteome Map
InterPro F-box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:26224 UniProtKB/Swiss-Prot
NCBI Gene 26224 ENTREZGENE
OMIM 605653 OMIM
PANTHER ES1 PROTEIN HOMOLOG, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-BOX DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam F-box UniProtKB/TrEMBL
  F-box-like UniProtKB/Swiss-Prot
PharmGKB PA28022 PharmGKB
SMART FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RB04 ENTREZGENE
  C9J0Y7_HUMAN UniProtKB/TrEMBL
  FBXL3_HUMAN UniProtKB/Swiss-Prot
  Q9P122 ENTREZGENE
  Q9UKT7 ENTREZGENE
UniProt Secondary B2RB04 UniProtKB/Swiss-Prot
  Q9P122 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-14 FBXL3  F-box and leucine rich repeat protein 3    F-box and leucine-rich repeat protein 3  Symbol and/or name change 5135510 APPROVED
2011-09-01 FBXL3  F-box and leucine-rich repeat protein 3  FBXL3  F-box and leucine-rich repeat protein 3  Symbol and/or name change 5135510 APPROVED