Asic5 (acid sensing ion channel subunit family member 5)

Gene: Asic5 (acid sensing ion channel subunit family member 5) Chinchilla lanigera

Analyze

Symbol:

Asic5

Name:

acid sensing ion channel subunit family member 5

RGD ID:

8707232

Description:

ENCODES a protein that exhibits ligand-gated sodium channel activity (ortholog); proton channel activity (ortholog); sodium channel activity (ortholog); INVOLVED IN sodium ion transmembrane transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); Habitual Abortions (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

acid sensing (proton gated) ion channel family member 5; acid-sensing (proton-gated) ion channel family member 5; acid-sensing ion channel 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955471	11,262,216 - 11,287,709 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955471	11,262,213 - 11,287,720 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Habitual Abortions (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

sodium ion transmembrane transport (ISO)

Molecular Function

ligand-gated sodium channel activity (ISO)

proton channel activity (ISO)

sodium channel activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Asic5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955471	11,262,216 - 11,287,709 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955471	11,262,213 - 11,287,720 (+)	NCBI	ChiLan1.0	ChiLan1.0

ASIC5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	155,829,729 - 155,866,277 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	155,829,729 - 155,866,277 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	156,750,881 - 156,787,429 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	156,970,331 - 157,006,875 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	157,108,485 - 157,145,030	NCBI
Celera	4	154,082,485 - 154,119,021 (-)	NCBI		Celera
Cytogenetic Map	4	q32.1	NCBI
HuRef	4	152,489,804 - 152,526,264 (-)	NCBI		HuRef
CHM1_1	4	156,728,541 - 156,765,056 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	159,162,518 - 159,198,985 (-)	NCBI		T2T-CHM13v2.0

Asic5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	81,889,600 - 81,928,540 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	81,889,597 - 81,928,540 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	81,982,293 - 82,021,233 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	81,982,290 - 82,021,233 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	81,800,844 - 81,825,155 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	82,082,849 - 82,107,160 (+)	NCBI		MGSCv36	mm8
Celera	3	82,022,407 - 82,046,104 (+)	NCBI		Celera
Cytogenetic Map	3	E3	NCBI
cM Map	3	35.97	NCBI

Asic5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	169,606,059 - 169,634,885 (+)	NCBI		GRCr8
mRatBN7.2	2	167,307,984 - 167,336,812 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	167,307,984 - 167,336,812 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	174,514,268 - 174,541,956 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	172,535,508 - 172,563,194 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	167,121,553 - 167,150,627 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	180,935,392 - 180,964,365 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	180,936,688 - 180,964,365 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	200,343,769 - 200,372,742 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	173,632,309 - 173,662,245 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	173,582,414 - 173,612,351 (+)	NCBI
Celera	2	161,337,695 - 161,366,476 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

ASIC5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	153,741,843 - 153,778,208 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	154,097,460 - 154,133,821 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	148,195,680 - 148,232,042 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	160,012,564 - 160,048,763 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	160,012,564 - 160,048,763 (-)	Ensembl	panpan1.1		panPan2

ASIC5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	53,343,244 - 53,376,328 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	53,343,907 - 53,377,347 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	53,678,867 - 53,711,918 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	54,050,367 - 54,083,462 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	54,051,045 - 54,084,648 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	53,303,775 - 53,336,887 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	53,413,177 - 53,446,093 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	53,727,107 - 53,760,202 (-)	NCBI		UU_Cfam_GSD_1.0

Asic5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	37,035,723 - 37,063,163 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936576	2,483,324 - 2,507,473 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936576	2,483,715 - 2,510,037 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ASIC5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	44,646,814 - 44,674,650 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	44,646,451 - 44,674,639 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	46,642,042 - 46,670,075 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ASIC5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	102,400,785 - 102,470,174 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	102,401,405 - 102,438,308 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	82,059,073 - 82,095,821 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Asic5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624848	2,421,378 - 2,448,550 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624848	2,421,380 - 2,448,626 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005400949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01053251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000010961 ⟹ ENSCLAP00000010828

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955471	11,262,216 - 11,287,709 (+)	Ensembl

RefSeq Acc Id:

XM_005400949 ⟹ XP_005401006

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955471	11,262,213 - 11,287,720 (+)	NCBI

Sequence:

show sequence

ATGGAGCAGTTTGAGAAACCGAAATCACACACTGAGAAAGGAGTCTTTGAAAAGGTAAAGCTTT
ATCTTCTGAGGAAGCCATTGCCATCTCCCACTGACGGAAGGAAGTTTGACCATGACTTTGCCAT
CTCCACTTCCTTTCATGGGGTTCACAATATTGTTCGGAACCGGAGCAAAATCCGAAGGGCAATC
TGGTTAGCCGTGGTGCTGGGCTCAGTCTCAGTCCTGGTGTGGCAGATCTACAGTCGCCTGGTCA
ACTACTTCACGTGGCCCACCACCACAGCCATAGAGGTGCAGTATGTGGAAAAGATTGAGTTTCC
TGCTGTGACATTCTGCAATTTGAACAGGTTCAAAGCAGATGCTGTAGCCAGATTTGGCATCATT
TACTTCTTATGGAGTATTGTATCCAAGGTTTTCCATGCTCAGGAAATCAGTGCCAATTCCACCG
GCTCTCAAGAGGCTGTTGATTTTGTAGTGACTCACCAAAACTTCAGCATTACAGAATTTGTAAA
GAACAGCGGGTTTTACCTCAGTAGAAGCACCTTGCTGTCATGCAACTTTTTCGGAAAACGATGT
GGCCCAGAGGATTTTAAACACATCTTCACTGAATACGGAAACTGTTTTACTTTCAATCATGGTG
AAAATATCCAAGAAAAGAAGAAAGTGAGTGTGTCTGGAAGAGGCTTAAACTTGGTGTTCGACGT
CCGCCAGGAGGAGTTTACGGATAGCTCAGCCCTTGGTTTTGCTGATGCAGGGATTGTCTTTGCT
ATTCATTCACCTAAAAAAGAACCACAGTTCGATGGCTTAGGCTTGTCCTCACCCGTGGGGATGC
ATGCCAGGGTGACAATCCGCCAACTAAAGACAGTTCACCAAGAATATCCCTGGGGCGAATGCAA
GCCTGATATCAAGCTGCGGAACTTCAGCAGCTATAGCACTTTCGGTTGCTTGAAGGAGTGCAAA
GCCCGGCACATAGAAAAGCAGTGCGGATGTCTGCCTTTTATGCTTCCAGGAAATGGAGTAGAAT
GTGAACTACATAAGTACTACAACTGCGTTTCTCCAGTCCTTGACCACATAGAGTTGAAGGAACT
CTGCACCATGGGAACACACAACTCCAGCTGCCCTGTGTCTTGTGAAGAGACAGAATACCCTGCT
TCCATTTCTTACTCCACCTTTCCCCGACAGAACGCTCTGAAGCATCTTTCCAAGAAGCTGAACC
AGAGCGAGGACTATATCAGACAGAATCTAGTGAACATTGAAATAAACTACAGTGATTTAAACTA
TAAGACAACCCAGCAGCAAAAGGCAGTCAGCGTGCCCGAGTTACTTGCAGATGTTGGTGGTCAG
CTGGGCCTATTTTGTGGGGCCAGTGTGATTACAATTATTGAAATCATTGAGTATATATTCACCA
ATTTCTACTGGCTGTGCCTTTTCTTTTTGCTGAAGATACCTGAAGTGACCCAGTGGCTTCCTGC
ATCTCAGAATCATCCTGGGAATAAAAATAGGATAGAAGAATGCTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005401006	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000010828
	ENSCLAP00000010828.1

RefSeq Acc Id:

XP_005401006 ⟸ XM_005400949

- UniProtKB:

A0A8C2V7F3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEQFEKPKSHTEKGVFEKVKLYLLRKPLPSPTDGRKFDHDFAISTSFHGVHNIVRNRSKIRRAI
WLAVVLGSVSVLVWQIYSRLVNYFTWPTTTAIEVQYVEKIEFPAVTFCNLNRFKADAVARFGII
YFLWSIVSKVFHAQEISANSTGSQEAVDFVVTHQNFSITEFVKNSGFYLSRSTLLSCNFFGKRC
GPEDFKHIFTEYGNCFTFNHGENIQEKKKVSVSGRGLNLVFDVRQEEFTDSSALGFADAGIVFA
IHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTVHQEYPWGECKPDIKLRNFSSYSTFGCLKECK
ARHIEKQCGCLPFMLPGNGVECELHKYYNCVSPVLDHIELKELCTMGTHNSSCPVSCEETEYPA
SISYSTFPRQNALKHLSKKLNQSEDYIRQNLVNIEINYSDLNYKTTQQQKAVSVPELLADVGGQ
LGLFCGASVITIIEIIEYIFTNFYWLCLFFLLKIPEVTQWLPASQNHPGNKNRIEEC

hide sequence

RefSeq Acc Id:

ENSCLAP00000010828 ⟸ ENSCLAT00000010961

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000007474	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000010961	ENTREZGENE
	ENSCLAT00000010961.1	UniProtKB/TrEMBL
Gene3D-CATH	Acid-sensing ion channels like domains	UniProtKB/TrEMBL
	YojJ-like	UniProtKB/TrEMBL
InterPro	ENaC	UniProtKB/TrEMBL
NCBI Gene	Asic5	ENTREZGENE
PANTHER	ACID-SENSING ION CHANNEL 5	UniProtKB/TrEMBL
	PTHR11690	UniProtKB/TrEMBL
Pfam	ASC	UniProtKB/TrEMBL
PRINTS	AMINACHANNEL	UniProtKB/TrEMBL
UniProt	A0A8C2V7F3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Asic5	acid sensing ion channel subunit family member 5		acid sensing (proton gated) ion channel family member 5	Symbol and/or name change	5135510	APPROVED
2015-08-25	Asic5	acid sensing (proton gated) ion channel family member 5		acid-sensing (proton-gated) ion channel family member 5	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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