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Gene: FAT2 (FAT atypical cadherin 2) Homo sapiens
Symbol: FAT2
Name: FAT atypical cadherin 2
RGD ID: 732170
Description: Predicted to have calcium ion binding activity. Involved in cell-substrate adhesion and epithelial cell migration. Localizes to adherens junction. Implicated in spinocerebellar ataxia 45.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cadherin family member 8; cadherin-related family member 9; CDHF8; CDHR9; FAT tumor suppressor homolog 2; HFAT2; MEGF1; multiple EGF-like domains protein 1; multiple epidermal growth factor-like domains 1; multiple epidermal growth factor-like domains protein 1; protocadherin Fat 2; protocadherin FAT2; SCA45
Mus musculus (house mouse) : Fat2 (FAT atypical cadherin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fat2 (FAT atypical cadherin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fat2 (FAT atypical cadherin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FAT2 (FAT atypical cadherin 2)
Canis lupus familiaris (dog) : FAT2 (FAT atypical cadherin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fat2 (FAT atypical cadherin 2)
Sus scrofa (pig) : FAT2 (FAT atypical cadherin 2)
Chlorocebus sabaeus (African green monkey) : FAT2 (FAT atypical cadherin 2)
Heterocephalus glaber (naked mole-rat) : Fat2 (FAT atypical cadherin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl5151,504,093 - 151,568,944 (-)EnsemblGRCh38hg38GRCh38
GRCh385151,504,092 - 151,594,822 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375150,883,653 - 150,948,505 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365150,863,847 - 150,928,698 (-)NCBINCBI36hg18NCBI36
Build 345150,863,846 - 150,928,698NCBI
Celera5146,965,062 - 147,029,916 (-)NCBI
Cytogenetic Map5q33.1NCBI
HuRef5146,029,050 - 146,093,922 (-)NCBIHuRef
CHM1_15150,316,083 - 150,380,950 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FAT2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732170
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.