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Gene: KISS1R (KISS1 receptor) Homo sapiens
Symbol: KISS1R
Name: KISS1 receptor
Description: Exhibits neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Localizes to several cellular components, including the cilium; integral component of membrane; and plasma membrane. Implicated in gonadal disease; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Biomarker of breast cancer; papillary carcinoma; and transitional cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AXOR12; CPPB1; G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; GPR54; HH8; HOT7T175; hypogonadotropin-1; kiSS-1 receptor; KISS-1R; kisspeptins receptor; metastin receptor
Mus musculus (house mouse) : Kiss1r (KISS1 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kiss1r (KISS1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kiss1r (KISS1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : KISS1R (KISS1 receptor)
Canis lupus familiaris (dog) : KISS1R (KISS1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kiss1r (KISS1 receptor)
Sus scrofa (pig) : KISS1R (KISS1 receptor)
Chlorocebus sabaeus (green monkey) : KISS1R (KISS1 receptor)
Heterocephalus glaber (naked mole-rat) : Kiss1r (KISS1 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl19917,287 - 921,005 (+)Ensembl
GRCh3819916,693 - 921,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3719917,342 - 921,015 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619868,358 - 872,013 (+)NCBINCBI36hg18NCBI36
Build 3419868,502 - 872,001NCBI
Celera19849,702 - 853,371 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef19690,992 - 694,661 (+)NCBIHuRef
CHM1_119916,929 - 920,598 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on KISS1R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731975
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.