Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CBR4 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Cbr4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CBR4 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | ISO | Cbr4 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of CBR4 mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Cbr4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CBR4 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Cbr4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBR4 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CBR4 mRNA | CTD | PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CBR4 mRNA | CTD | PMID:33387578 | 2-methylcholine | affects expression | ISO | CBR4 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of CBR4 mRNA | CTD | PMID:21179406 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of CBR4 gene | CTD | PMID:31601247 | 5-aza-2'-deoxycytidine | affects expression | ISO | CBR4 (Homo sapiens) | 6480464 | Decitabine affects the expression of CBR4 mRNA | CTD | PMID:23300844 | 8-Br-cAMP | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CBR4 mRNA | CTD | PMID:22079614 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of CBR4 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of CBR4 mRNA | CTD | PMID:33354967 | arsane | affects methylation | ISO | CBR4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of CBR4 gene | CTD | PMID:25304211 | arsane | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of CBR4 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of CBR4 mRNA | CTD | PMID:32525701 | arsenic atom | affects methylation | ISO | CBR4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of CBR4 gene | CTD | PMID:25304211 | arsenous acid | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CBR4 mRNA | CTD | PMID:27829220 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CBR4 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CBR4 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CBR4 mRNA | CTD | PMID:33670352 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of CBR4 mRNA | CTD | PMID:24136188 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of CBR4 promoter | CTD | PMID:22457795 | carbon nanotube | increases expression | ISO | Cbr4 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of CBR4 mRNA | CTD | PMID:25620056 | cisplatin | affects expression | ISO | CBR4 (Homo sapiens) | 6480464 | Cisplatin affects the expression of CBR4 mRNA | CTD | PMID:23300844 | cisplatin | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of CBR4 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of CBR4 mRNA | CTD | PMID:19320972 and PMID:19376846 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of CBR4 mRNA | CTD | PMID:24386269 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CBR4 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CBR4 mRNA | CTD | PMID:20106945 more ... | diarsenic trioxide | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CBR4 mRNA | CTD | PMID:27829220 | dibutyl phthalate | decreases expression | ISO | Cbr4 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of CBR4 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of CBR4 mRNA | CTD | PMID:28302478 | doxorubicin | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CBR4 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CBR4 mRNA | CTD | PMID:29391264 | folic acid | multiple interactions | ISO | Cbr4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CBR4 mRNA | CTD | PMID:22206623 | fulvestrant | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CBR4 gene and [bisphenol S co-treated with Fulvestrant] results in decreased methylation of CBR4 gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of CBR4 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of CBR4 mRNA | CTD | PMID:24136188 | hydrogen peroxide | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of CBR4 mRNA | CTD | PMID:18951874 | ivermectin | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CBR4 protein | CTD | PMID:32959892 | methylmercury chloride | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of CBR4 mRNA | CTD | PMID:23179753 | methylmercury chloride | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CBR4 mRNA | CTD | PMID:28001369 | NAD zwitterion | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | NAD binds to and results in increased activity of CBR4 protein | CTD | PMID:25526675 | NAD(+) | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | NAD binds to and results in increased activity of CBR4 protein | CTD | PMID:25526675 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of CBR4 mRNA | CTD | PMID:24136188 | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of CBR4 mRNA | CTD | PMID:33484710 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of CBR4 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | Cbr4 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of CBR4 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Cbr4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CBR4 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CBR4 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of CBR4 mRNA | CTD | PMID:21420995 and PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Cbr4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CBR4 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of CBR4 protein | CTD | PMID:26879310 | phenobarbital | affects expression | ISO | CBR4 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of CBR4 mRNA | CTD | PMID:19159669 | pirinixic acid | increases expression | ISO | Cbr4 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of CBR4 mRNA | CTD | PMID:17426115 | potassium chromate | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of CBR4 mRNA | CTD | PMID:22714537 | quercetin | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of CBR4 mRNA | CTD | PMID:21632981 | sodium arsenate | multiple interactions | ISO | CBR4 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of CBR4 mRNA | CTD | PMID:32525701 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of CBR4 protein | CTD | PMID:29459688 | temozolomide | decreases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of CBR4 mRNA | CTD | PMID:31758290 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CBR4 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Cbr4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of CBR4 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of CBR4 mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of CBR4 mRNA | CTD | PMID:34492290 | tolcapone | decreases expression | EXP | | 6480464 | tolcapone results in decreased expression of CBR4 mRNA | CTD | PMID:24136188 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of CBR4 mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CBR4 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of CBR4 mRNA | CTD | PMID:24935251 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of CBR4 mRNA | CTD | PMID:30589522 | valproic acid | increases expression | ISO | CBR4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CBR4 mRNA | CTD | PMID:23179753 and PMID:28001369 | valproic acid | affects expression | ISO | CBR4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CBR4 mRNA | CTD | PMID:25979313 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of CBR4 mRNA | CTD | PMID:23555832 | |