CBR4 (carbonyl reductase 4) - Rat Genome Database

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Gene: CBR4 (carbonyl reductase 4) Sus scrofa
Analyze
Symbol: CBR4
Name: carbonyl reductase 4
RGD ID: 14014130
Description: ENCODES a protein that exhibits 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (inferred); NAD(P)H dehydrogenase (quinone) activity (inferred); NADPH binding (inferred); INVOLVED IN daunorubicin metabolic process (inferred); doxorubicin metabolic process (inferred); fatty acid biosynthetic process (inferred); ASSOCIATED WITH genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); pancreatic adenocarcinoma (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: carbonyl reductase family member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,621,981 - 20,682,240 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11420,621,960 - 20,642,351 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,908,782 - 21,929,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CBR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1420,621,981 - 20,682,240 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11420,621,960 - 20,642,351 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21421,908,782 - 21,929,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CBR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384168,894,486 - 169,010,255 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4168,863,770 - 169,010,275 (-)EnsemblGRCh38hg38GRCh38
GRCh374169,908,741 - 169,931,406 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364170,145,316 - 170,167,997 (-)NCBINCBI36Build 36hg18NCBI36
Celera4167,240,084 - 167,262,804 (-)NCBICelera
Cytogenetic Map4q32.3NCBI
HuRef4165,662,191 - 165,684,917 (-)NCBIHuRef
CHM1_14169,885,180 - 169,907,907 (-)NCBICHM1_1
T2T-CHM13v2.04172,254,054 - 172,369,681 (-)NCBIT2T-CHM13v2.0
Cbr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39861,940,768 - 61,956,534 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl861,940,768 - 61,959,728 (+)EnsemblGRCm39 Ensembl
GRCm38861,487,734 - 61,503,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl861,487,734 - 61,506,694 (+)EnsemblGRCm38mm10GRCm38
MGSCv37863,966,531 - 63,982,297 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36864,379,926 - 64,395,624 (+)NCBIMGSCv36mm8
MGSCv36860,656,117 - 60,671,212 (+)NCBIMGSCv36mm8
Celera864,050,917 - 64,066,676 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map831.18NCBI
Cbr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81633,625,734 - 33,695,067 (-)NCBIGRCr8
mRatBN7.21628,629,928 - 28,684,230 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1628,617,224 - 28,645,712 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1632,224,831 - 32,240,582 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01635,658,872 - 35,674,623 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01631,860,531 - 31,876,269 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01631,944,328 - 31,972,553 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1631,956,753 - 31,972,507 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01631,794,520 - 31,810,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41631,943,125 - 31,957,556 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11631,943,200 - 31,957,630 (-)NCBI
Celera1628,625,441 - 28,641,135 (-)NCBICelera
Cytogenetic Map16p12NCBI
Cbr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540337,206,634 - 37,226,407 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540337,201,474 - 37,226,414 (+)NCBIChiLan1.0ChiLan1.0
CBR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23166,663,224 - 166,794,172 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14167,015,483 - 167,149,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04161,103,477 - 161,235,840 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14173,182,755 - 173,309,905 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4173,282,162 - 173,309,905 (-)Ensemblpanpan1.1panPan2
CBR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12519,475,562 - 19,618,144 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2519,597,518 - 19,618,180 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2519,566,496 - 19,649,192 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02519,673,638 - 19,756,294 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2519,734,924 - 19,756,246 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12519,541,290 - 19,623,984 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02519,541,898 - 19,624,490 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02519,604,132 - 19,686,873 (-)NCBIUU_Cfam_GSD_1.0
Cbr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494320,768,596 - 20,791,385 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365161,181,524 - 1,205,760 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365161,184,859 - 1,205,668 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17115,223,813 - 115,246,925 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7115,223,386 - 115,246,818 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603795,082,408 - 95,160,389 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624769581,800 - 604,075 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624769564,148 - 603,402 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CBR4
1010 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000010653   ⟹   ENSSSCP00000010376
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,622,023 - 20,643,486 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000082083   ⟹   ENSSSCP00000065525
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,621,981 - 20,641,819 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000084941   ⟹   ENSSSCP00000069120
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1420,621,981 - 20,682,240 (+)Ensembl
RefSeq Acc Id: XM_001927085   ⟹   XP_001927120
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,621,960 - 20,642,351 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657284   ⟹   XP_005657341
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,621,960 - 20,629,664 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021072857   ⟹   XP_020928516
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11420,621,960 - 20,638,631 (+)NCBI
Sequence:
RefSeq Acc Id: XP_001927120   ⟸   XM_001927085
- Peptide Label: isoform X1
- UniProtKB: F1RIX8 (UniProtKB/TrEMBL),   A0A4X1V1P4 (UniProtKB/TrEMBL),   A0A4X1V2R2 (UniProtKB/TrEMBL),   A0A5G2QL25 (UniProtKB/TrEMBL),   A0A8D0XGB1 (UniProtKB/TrEMBL),   A0A8D1WSJ8 (UniProtKB/TrEMBL),   A0A8D0R983 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928516   ⟸   XM_021072857
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005657341   ⟸   XM_005657284
- Peptide Label: isoform X3
- UniProtKB: A0A8D0R9E0 (UniProtKB/TrEMBL),   A0A4X1V072 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000010376   ⟸   ENSSSCT00000010653
Ensembl Acc Id: ENSSSCP00000069120   ⟸   ENSSSCT00000084941
Ensembl Acc Id: ENSSSCP00000065525   ⟸   ENSSSCT00000082083


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009717 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005033462 UniProtKB/TrEMBL
  ENSSSCG00015040654 UniProtKB/TrEMBL
  ENSSSCG00025021937 UniProtKB/TrEMBL
  ENSSSCG00030057256 UniProtKB/TrEMBL
  ENSSSCG00035054913 UniProtKB/TrEMBL
  ENSSSCG00040051626 UniProtKB/TrEMBL
  ENSSSCG00045017708 UniProtKB/TrEMBL
  ENSSSCG00050025561 UniProtKB/TrEMBL
  ENSSSCG00055003467 UniProtKB/TrEMBL
  ENSSSCG00060072077 UniProtKB/TrEMBL
  ENSSSCG00065063566 UniProtKB/TrEMBL
  ENSSSCG00070020957 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010653 ENTREZGENE
  ENSSSCT00000010653.4 UniProtKB/TrEMBL
  ENSSSCT00000082083.2 UniProtKB/TrEMBL
  ENSSSCT00000084941.2 UniProtKB/TrEMBL
  ENSSSCT00005053482.1 UniProtKB/TrEMBL
  ENSSSCT00015054220.1 UniProtKB/TrEMBL
  ENSSSCT00015054263.1 UniProtKB/TrEMBL
  ENSSSCT00025029872.1 UniProtKB/TrEMBL
  ENSSSCT00025029882.1 UniProtKB/TrEMBL
  ENSSSCT00025029886.1 UniProtKB/TrEMBL
  ENSSSCT00030079831.1 UniProtKB/TrEMBL
  ENSSSCT00030079860.1 UniProtKB/TrEMBL
  ENSSSCT00035073259.1 UniProtKB/TrEMBL
  ENSSSCT00040069729.1 UniProtKB/TrEMBL
  ENSSSCT00040069787.1 UniProtKB/TrEMBL
  ENSSSCT00045030159.1 UniProtKB/TrEMBL
  ENSSSCT00050034419.1 UniProtKB/TrEMBL
  ENSSSCT00050034503.1 UniProtKB/TrEMBL
  ENSSSCT00055006774.1 UniProtKB/TrEMBL
  ENSSSCT00060098460.1 UniProtKB/TrEMBL
  ENSSSCT00060098489.1 UniProtKB/TrEMBL
  ENSSSCT00065087209.1 UniProtKB/TrEMBL
  ENSSSCT00065087223.1 UniProtKB/TrEMBL
  ENSSSCT00070041642.1 UniProtKB/TrEMBL
  ENSSSCT00070041653.1 UniProtKB/TrEMBL
  ENSSSCT00070041658.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
KEGG Report ssc:100153608 UniProtKB/TrEMBL
NCBI Gene CBR4 ENTREZGENE
PANTHER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  adh_short_C2 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
SMART PKS_KR UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A4X1V072 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V1P4 ENTREZGENE
  A0A4X1V2R2 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QL25 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R4K8_PIG UniProtKB/TrEMBL
  A0A8D0R983 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0R9E0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0XGB1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WSJ8 ENTREZGENE, UniProtKB/TrEMBL
  F1RIX8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1V1P4 UniProtKB/TrEMBL
VGNC ID VGNC:86229 ENTREZGENE