Tmigd3 (transmembrane and immunoglobulin domain containing 3) - Rat Genome Database

Tmigd3 (transmembrane and immunoglobulin domain containing 3) - Rat Genome Database

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Gene: Tmigd3 (transmembrane and immunoglobulin domain containing 3) Rattus norvegicus

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Symbol:

Tmigd3

Name:

transmembrane and immunoglobulin domain containing 3

RGD ID:

2324712

Description:

Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in several processes, including immune response-activating signaling pathway; negative regulation of NF-kappaB transcription factor activity; and negative regulation of cell migration. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TMIGD3 (transmembrane and immunoglobulin domain containing 3); INTERACTS WITH trichloroethene; leflunomide (ortholog).

Type:

protein-coding

RefSeq Status:

Previously known as:

Adora3 protein-like; LOC100363178

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

LOC100911347

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	196,027,286 - 196,103,430 (+)	NCBI		GRCr8
mRatBN7.2	2	193,338,950 - 193,415,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	193,338,950 - 193,415,105 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	200,933,404 - 201,009,584 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	198,829,211 - 198,905,343 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	193,646,168 - 193,722,310 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	208,478,373 - 208,557,356 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	208,323,882 - 208,557,356 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	227,900,017 - 227,978,209 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	201,107,970 - 201,186,359 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	186,040,322 - 186,117,254 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmigd3	Rat	COVID-19		ISO	TMIGD3 (Homo sapiens)	9068941	mRNA:increased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226 and REF_RGD_ID:28912744

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmigd3	Rat	autistic disorder		ISO	TMIGD3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism	ClinVar

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmigd3	Rat	leflunomide	increases expression	ISO	TMIGD3 (Homo sapiens)	6480464	leflunomide results in increased expression of TMIGD3 mRNA	CTD	PMID:28988120
Tmigd3	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of TMIGD3 mRNA	CTD	PMID:33387578

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmigd3	Rat	immune response-activating signaling pathway	involved_in	IBA	MGI:2687214 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tmigd3	Rat	negative regulation of cell migration	involved_in	ISO	TMIGD3 (Homo sapiens)	1624291	PMID:27886186	RGD	PMID:27886186
Tmigd3	Rat	negative regulation of cell population proliferation	involved_in	ISO	TMIGD3 (Homo sapiens)	1624291	PMID:27886186	RGD	PMID:27886186
Tmigd3	Rat	negative regulation of NF-kappaB transcription factor activity	involved_in	ISO	TMIGD3 (Homo sapiens)	1624291	PMID:27886186	RGD	PMID:27886186

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmigd3	Rat	membrane	located_in	ISO	TMIGD3 (Homo sapiens)	1624291	PMID:27886186	RGD	PMID:27886186
Tmigd3	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tmigd3	Rat	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Tmigd3	Rat	plasma membrane	is_active_in	IBA	MGI:1289168 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmigd3	Rat	transmembrane signaling receptor activity	enables	IBA	MGI:1913150 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12477932	PMID:27886186

Tmigd3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	196,027,286 - 196,103,430 (+)	NCBI		GRCr8
mRatBN7.2	2	193,338,950 - 193,415,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	193,338,950 - 193,415,105 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	200,933,404 - 201,009,584 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	198,829,211 - 198,905,343 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	193,646,168 - 193,722,310 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	208,478,373 - 208,557,356 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	208,323,882 - 208,557,356 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	227,900,017 - 227,978,209 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	201,107,970 - 201,186,359 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	186,040,322 - 186,117,254 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

TMIGD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	111,483,348 - 111,563,962 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	111,483,348 - 111,563,962 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	112,025,970 - 112,106,584 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	1	p13.2	NCBI
CHM1_1	1	112,140,977 - 112,221,590 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	111,498,030 - 111,578,832 (-)	NCBI		T2T-CHM13v2.0

Tmigd3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	105,778,174 - 105,831,360 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	105,811,799 - 105,826,108 (+)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	3	105,778,174 - 105,816,242 (+)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	3	105,778,219 - 105,831,358 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	105,870,858 - 105,924,044 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	105,904,483 - 105,918,792 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	3	105,870,858 - 105,908,926 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	3	105,870,903 - 105,924,042 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv36	3	105,998,963 - 106,052,092 (+)	NCBI		MGSCv36	mm8
Celera	3	108,059,748 - 108,112,934 (+)	NCBI		Celera
Cytogenetic Map	3	F2.2	NCBI

TMIGD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	63,904,582 - 63,907,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	63,418,171 - 63,420,460 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	65,076,072 - 65,078,361 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	17	63,811,019 - 63,813,306 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	63,869,840 - 63,872,128 (+)	NCBI		UNSW_CanFamBas_1.0

TMIGD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	108,854,357 - 108,873,925 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	108,814,405 - 108,871,101 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	118,996,431 - 119,053,021 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

.

Variants in Tmigd3
315 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	229
Count of miRNA genes:	162
Interacting mature miRNAs:	184
Transcripts:	ENSRNOT00000021288
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	184114274	202447032	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	185876309	219753474	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	189599258	226936289	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	189599258	218414891	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	189599258	234599258	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	190613715	226808892	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189599258	234599258	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat

ADORA3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	193,391,343 - 193,391,754 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	208,533,494 - 208,533,904	NCBI	Rnor6.0
Rnor_6.0	2	208,375,791 - 208,376,201	NCBI	Rnor6.0
Rnor_5.0	2	227,795,692 - 227,796,102	UniSTS	Rnor5.0
Rnor_5.0	2	227,954,972 - 227,955,382	UniSTS	Rnor5.0
RGSC_v3.4	2	201,160,413 - 201,160,823	UniSTS	RGSC3.4
Celera	2	186,092,710 - 186,093,120	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH94668

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	193,392,060 - 193,392,199 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	208,534,211 - 208,534,349	NCBI	Rnor6.0
Rnor_6.0	2	208,376,508 - 208,376,646	NCBI	Rnor6.0
Rnor_5.0	2	227,955,689 - 227,955,827	UniSTS	Rnor5.0
Rnor_5.0	2	227,796,409 - 227,796,547	UniSTS	Rnor5.0
RGSC_v3.4	2	201,161,130 - 201,161,268	UniSTS	RGSC3.4
Celera	2	186,093,427 - 186,093,565	UniSTS
RH 3.4 Map	2	1369.2	UniSTS
Cytogenetic Map	2	q34	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	1	6	26	26	22	10	12	10	6	52	30	14	3	25	12


RefSeq Transcripts	NM_001302749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC097395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM077301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021288 ⟹ ENSRNOP00000021288

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,338,950 - 193,410,796 (+)	Ensembl
Rnor_6.0 Ensembl	2	208,541,361 - 208,556,973 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000075939 ⟹ ENSRNOP00000068169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,338,950 - 193,415,105 (+)	Ensembl
Rnor_6.0 Ensembl	2	208,478,527 - 208,557,356 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085178 ⟹ ENSRNOP00000072287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,400,082 - 193,415,105 (+)	Ensembl
Rnor_6.0 Ensembl	2	208,323,882 - 208,557,354 (+)	Ensembl

RefSeq Acc Id:

NM_001302749 ⟹ NP_001289678

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,286 - 196,103,430 (+)	NCBI
mRatBN7.2	2	193,338,950 - 193,415,107 (+)	NCBI
Rnor_6.0	2	208,478,373 - 208,557,356 (+)	NCBI
Celera	2	186,040,322 - 186,117,254 (+)	NCBI

Sequence:

show sequence

TTACAGTTTCACAGCATCCAAATGGCTTGGAAAATCTGAGTGTGTCTGAGGCTCTGCTCTTACAGTCAAGGCATGCCTGCCTGGTTCTCTAGAGAAGGGTTGGAGGGATGGAATGTGGCTGCTGCAAG
CTTCCATGGCAGTTGCTAAAGATGACCAGATGGACCTGCAGGACTTCAGCGGGACCCACTGACCAAGAAGGGCAGATCCAGGGTTCCTGAGATCCTCCCTCGAGTTATTCCAGCTGAAGGCTCACTTC
CTTCTCAGCATGGAGCCCCTCCTACTGCTCTCCTTGGCTCTCTTTTCCGATGCCATGGTCATGGATGAAAAGGTGAAATCAGGCGTTGAGCTGGACACAGCTTCTGCAATCTGTAACTATGACGCCCA
CTACAAGGACCACACCAAGTACTGGTGCCGTGGCTATTTCAGGGACTCGTGCAACATTATTGCCTTCACCCCTAATAGCAGCAACCGTGTGGCCCTGAAAGACACAGGAGACCAACTCATCATCACTG
TCTCCTGCCTGGTCAAGGAGGACACAGGCTGGTACTGGTGTGGTATCCAGCGGGACTTTGCCAGAGATGACATGGATTTTACAAAGCTGATTGTGACTGACAACAGAGAAGACCGGGCCAATGGCCTT
TCACCTGGCACTTCAGGCAACAGGACCCGGAGCTGTAAGACGTCCAAAGCTGTTCAAAAGGCAGAGGGCTCCCGAATGTCCATTCTGATCGTTTGTGTACTGATTAGCGGGCTGGGGATCATCTTTTT
AATCAGTCATATGTCCAGAGGAAGACGAAGCCAAAGAAACAGAGGAGTTACTGGCAAAAGCATCAATAGAAACCCACAAGCAAGTCAAGCTCCGTCCATGGTCTCCATCCCCTTGACTGTCCTTCCCA
AGGTCCCAAGACAAAATGGTCAACAAAAAGCCCTCCAATGGACTGGAAATGCCACAAAGACCGGATAAGTGTATTCCTTTACTTGGGTTTGAAGGAATAGGGTGTAGAACTGGTCACTGGGGCTGCCG
TGGAGATTGTTCCTGCAGAGAACATGGAAGGTATCAGTTTTGGGGGGATCAGTATCTCTGCCCTACTCCTGCCGTCCCTCTCGGATAAGACCCTGAGCACGACCACTACCCACGGGAACTTGCAAGCC
GGCTACAACTCTTCAGAGGGAAGGGCAGTGAGTCTTTTCGCTGGTGCTGGGCAAGTGAACCCAGGACTGTTTGCACACTGGGTCAAGCCCTCTACCACTGAGCTACATGCTATATCTCAGTGAGACCT
TTAAAATGAGAAGTAGAGCTGTACTTGAAAGGGTATACGAAATAAAGGAGCAGAGGTAGAGTGGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017590568 ⟹ XP_017446057

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,041,074 - 196,099,110 (+)	NCBI
mRatBN7.2	2	193,399,151 - 193,411,065 (+)	NCBI
Rnor_6.0	2	208,541,299 - 208,553,179 (+)	NCBI

Sequence:

show sequence

ATCCAGGGTTCCTGAGATCCTCCCTCGAGTTATTCCAGCTGAAGGCTCACTTCCTTCTCAGCATGGAGCCCCTCCTACTGCTCTCCTTGGCTCTCTTTTCCGATGCCATGGTCATGGATGAAAAGGTG
AAATCAGGCGTTGAGCTGGACACAGCTTCTGCAATCTGTAACTATGACGCCCACTACAAGGACCACACCAAGTACTGGTGCCGTGGCTATTTCAGGGACTCGTGCAACATTATTGCCTTCACCCCTAA
TAGCAGCAACCGTGTGGCCCTGAAAGACACAGGAGACCAACTCATCATCACTGTCTCCTGCCTGGTCAAGGAGGACACAGGCTGGTACTGGTGTGGTATCCAGCGGGACTTTGCCAGAGATGACATGG
ATTTTACAAAGCTGATTGTGACTGACAACAGAGAAGACCGGGCCAATGGCCTTTCACCTGGCACTTCAGGCAACAGGACCCGGAGCTGTAAGACGTCCAAAGCTGTTCAAAAGGCAGAGGGCTCCCGA
ATGTCCATTCTGATCGTTTGTGTACTGATTAGCGGGCTGGGGATCATCTTTTTAATCAGTCATATGTCCAGAGGAAGACGAAGCCAAAGAAACAGAGGAGTTACTGGCAAAAGCATCAATAGAAACCC
ACAAGCAAGTCAAGCTCCGTCCATGGTCTCCATCCCCTTGGCAACGATTTGAAGTTCTTTCCACATGTCCTGACTCAAGGAAATGGCTCAAGCAGAACGCGTGTGACTGAAGATTTATTTCATTTAGC
TCCTAAATAAAGTGATATCATTACAGTAGACTCTCCATGCCAACTGGTCTGCATCTCAGAGACTGACTCTGACCTTTCAGGATTTCTAAAGGACTCTGTGACCTTGCAGCAATCTTTTATGGCCGATG
GCAACAGTGAGGCTCGGAAGATCTTTGGAGGAAGGCTGCCATT

hide sequence

RefSeq Acc Id:

XM_017590570 ⟹ XP_017446059

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,446 - 196,099,110 (+)	NCBI
mRatBN7.2	2	193,399,151 - 193,411,065 (+)	NCBI
Rnor_6.0	2	208,541,299 - 208,553,179 (+)	NCBI

Sequence:

show sequence

ATCCAGGGTTCCTGAGATCCTCCCTCGAGTTATTCCAGCTGAAGGCTCACTTCCTTCTCAGCAT
GGAGCCCCTCCTACTGCTCTCCTTGGCTCTCTTTTCCGATGCCATGGTCATGGATGAAAAGGTGAAATCAGGCGTTGAGCTGGACACAGCTTCTGCAATCTGTAACTATGACGCCCACTACAAGGACC
ACACCAAGTACTGGTGCCGTGGCTATTTCAGGGACTCGTGCAACATTATTGCCTTCACCCCTAATAGCAGCAACCGTGTGGCCCTGAAAGACACAGGAGACCAACTCATCATCACTGTCTCCTGCCTG
GTCAAGGAGGACACAGGCTGGTACTGGTGTGGTATCCAGCGGGACTTTGCCAGAGATGACATGGATTTTACAAAGCTGATTGTGACTGACAACAGAGAAGACCGGGCCAATGGCCTTTCACCTGGCAC
TTCAGGCAACAGGACCCGGAGCTGTAAGACGTCCAAAGCTGTTCAAAAGGCAGAGGGCTCCCGAATGTCCATTCTGATCGTTTGTGTACTGATTAGCGGGCTGGGGATCATCTTTTTAATCAGTCATA
TGTCCAGAGGAAGACGAAGCCAAAGAAACAGAGGAGTTACTGGCAAAAGCATCAATAGAAACCCACAAGCAAGTCAAGCTCCGTCCATGGTCTCCATCCCCTTGTAGGCAACGATTTGAAGTTCTTTC
CACATGTCCTGACTCAAGGAAATGGCTCAAGCAGAACGCGTGTGACTGAAGATTTATTTCATTTAGCTCCTAAATAAAGTGATATCATTACAGTAGACTCTCCATGCCAACTGGTCTGCATCTCAGAG
ACTGACTCTGACCTTTCAGGATTTCTAAAGGACTCTGTGACCTTGCAGCAATCTTTTATGGCCGATGGCAACAGTGAGGCTCGGAAGATCTTTGGAGGAAGGCTGCCATT

hide sequence

RefSeq Acc Id:

XM_063281089 ⟹ XP_063137159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,446 - 196,099,110 (+)	NCBI

RefSeq Acc Id:

XM_063281090 ⟹ XP_063137160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,473 - 196,099,110 (+)	NCBI

RefSeq Acc Id:

XM_063281091 ⟹ XP_063137161

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,075,804 - 196,099,110 (+)	NCBI


Protein RefSeqs	NP_001289678	(Get FASTA)	NCBI Sequence Viewer
	XP_017446057	(Get FASTA)	NCBI Sequence Viewer
	XP_017446059	(Get FASTA)	NCBI Sequence Viewer
	XP_063137159	(Get FASTA)	NCBI Sequence Viewer
	XP_063137160	(Get FASTA)	NCBI Sequence Viewer
	XP_063137161	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97395	(Get FASTA)	NCBI Sequence Viewer
	EDL81822	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021288
	ENSRNOP00000021288.5
	ENSRNOP00000068169
	ENSRNOP00000068169.1
	ENSRNOP00000072287.2

RefSeq Acc Id:	NP_001289678 ⟸ NM_001302749
- Peptide Label:	precursor
- UniProtKB:	Q4V8H0 (UniProtKB/TrEMBL), F7FB47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPG TSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG hide sequence

RefSeq Acc Id:	XP_017446059 ⟸ XM_017590570
- Peptide Label:	isoform X2
- UniProtKB:	F7FB47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPG TSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPL hide sequence

RefSeq Acc Id:	XP_017446057 ⟸ XM_017590568
- Peptide Label:	isoform X3
- UniProtKB:	A6HUN7 (UniProtKB/TrEMBL), F7FB47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPG TSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLATI hide sequence

Ensembl Acc Id:

ENSRNOP00000021288 ⟸ ENSRNOT00000021288

Ensembl Acc Id:

ENSRNOP00000072287 ⟸ ENSRNOT00000085178

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8H0-F1-model_v2	AlphaFold	Q4V8H0	1-232	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

Promoter ID:

Type:

initiation region

Name:

Tmigd3_1

Description:

transmembrane and immunoglobulin domain containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	208,478,511 - 208,478,571	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-51721	BioCyc
Ensembl Genes	ENSRNOG00000043375	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021288	ENTREZGENE
	ENSRNOT00000021288.7	UniProtKB/TrEMBL
	ENSRNOT00000075939	ENTREZGENE
	ENSRNOT00000075939.3	UniProtKB/TrEMBL
	ENSRNOT00000085178.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	CD300_family_receptors	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
KEGG Report	rno:100363178	UniProtKB/TrEMBL
NCBI Gene	100363178	ENTREZGENE
PANTHER	POLYMERIC-IMMUNOGLOBULIN RECEPTOR	UniProtKB/TrEMBL
	TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN TMIGD3	UniProtKB/TrEMBL
PhenoGen	Tmigd3	PhenoGen
RatGTEx	ENSRNOG00000043375	RatGTEx
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A0G2K2L2_RAT	UniProtKB/TrEMBL
	A6HUN7	ENTREZGENE, UniProtKB/TrEMBL
	F7FB47	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8H0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-09	Tmigd3	transmembrane and immunoglobulin domain containing 3	LOC100363178	Adora3 protein-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-12	LOC100363178	Adora3 protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL