Gene: Araf (A-Raf proto-oncogene, serine/threonine kinase) Rattus norvegicus
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Symbol: Araf
Name: A-Raf proto-oncogene, serine/threonine kinase
Description: ENCODES a protein that exhibits MAP kinase kinase kinase activity; protein serine/threonine kinase activity (ortholog); INVOLVED IN protein phosphorylation; immortalization of host cell (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Breast Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytosol; mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-Raf proto-oncogene serine/threonine-protein kinase; Araf1; proto-oncogene A-Raf; proto-oncogene A-Raf-1; Raf related protein; Ras-binding protein; serine/threonine-protein kinase A-Raf; v-raf murine sarcoma 3611 viral oncogene homolog; v-raf murine sarcoma 3611 viral oncogene homolog 1; v-raf oncogene homolog 1 (murine sarcoma 3611 virus)
Orthologs:
Homo sapiens (human) : ARAF (A-Raf proto-oncogene, serine/threonine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Araf (Araf proto-oncogene, serine/threonine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Araf (A-Raf proto-oncogene, serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ARAF (A-Raf proto-oncogene, serine/threonine kinase)
Canis lupus familiaris (dog) : ARAF (A-Raf proto-oncogene, serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Araf (A-Raf proto-oncogene, serine/threonine kinase)
Sus scrofa (pig) : ARAF (A-Raf proto-oncogene, serine/threonine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X1,369,534 - 1,391,603 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X2,194,385 - 2,206,064 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,556,904 - 12,568,583 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X12,562,471 - 12,572,791 (-)NCBI
CeleraX1,795,227 - 1,806,868 (-)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Araf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2148
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE