Mastl (microtubule associated serine/threonine kinase like) - Rat Genome Database

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Gene: Mastl (microtubule associated serine/threonine kinase like) Heterocephalus glaber
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Symbol: Mastl
Name: microtubule associated serine/threonine kinase like
RGD ID: 18933592
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); protein serine/threonine kinase activity (inferred); INVOLVED IN female meiosis II (ortholog); G2/M transition of mitotic cell cycle (ortholog); meiotic chromosome condensation (ortholog); ASSOCIATED WITH Scimitar Anomaly, Multiple Cardiac Malformations, and Craniofacial and Central Nervous System Abnormalities (ortholog); thrombocytopenia (ortholog); Thrombocytopenia 2 (ortholog); FOUND IN centrosome (ortholog); cleavage furrow (ortholog); meiotic spindle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase greatwall
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247962,216,034 - 2,243,962 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247962,215,951 - 2,244,307 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mastl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247962,216,034 - 2,243,962 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247962,215,951 - 2,244,307 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MASTL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381027,154,479 - 27,187,953 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1027,154,824 - 27,187,953 (+)EnsemblGRCh38hg38GRCh38
GRCh371027,444,281 - 27,476,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361027,484,298 - 27,515,854 (+)NCBINCBI36Build 36hg18NCBI36
Build 341027,484,297 - 27,515,854NCBI
Celera1027,160,210 - 27,192,290 (+)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1027,112,454 - 27,144,522 (+)NCBIHuRef
CHM1_11027,443,697 - 27,475,780 (+)NCBICHM1_1
T2T-CHM13v2.01027,184,483 - 27,217,949 (+)NCBIT2T-CHM13v2.0
Mastl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39223,006,549 - 23,046,036 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl223,005,618 - 23,046,036 (-)EnsemblGRCm39 Ensembl
GRCm38223,116,539 - 23,156,024 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl223,115,606 - 23,156,024 (-)EnsemblGRCm38mm10GRCm38
MGSCv37222,972,064 - 23,011,544 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36222,940,074 - 22,977,925 (-)NCBIMGSCv36mm8
Celera222,848,204 - 22,887,677 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map215.23NCBI
Mastl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81790,158,592 - 90,195,550 (-)NCBIGRCr8
mRatBN7.21785,250,512 - 85,287,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1785,251,997 - 85,287,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1788,736,222 - 88,771,568 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01792,571,598 - 92,606,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01786,588,377 - 86,623,723 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01789,839,562 - 89,875,855 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1789,742,140 - 89,876,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01791,504,296 - 91,540,607 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41796,722,615 - 96,757,971 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11796,733,772 - 96,751,272 (-)NCBI
Celera1783,608,795 - 83,644,003 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Mastl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554292,591,203 - 2,617,784 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554292,591,173 - 2,617,084 (+)NCBIChiLan1.0ChiLan1.0
MASTL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2839,783,630 - 39,816,414 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11039,788,957 - 39,821,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01027,264,475 - 27,296,085 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11027,626,892 - 27,658,180 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1027,626,892 - 27,658,180 (+)Ensemblpanpan1.1panPan2
MASTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.126,829,309 - 6,863,876 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl26,830,168 - 6,863,568 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha25,582,408 - 5,616,987 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.025,018,871 - 5,053,474 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl25,019,818 - 5,053,476 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.124,395,980 - 4,430,831 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.024,472,486 - 4,507,336 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.024,639,192 - 4,673,999 (+)NCBIUU_Cfam_GSD_1.0
Mastl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934426,109,771 - 26,141,730 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364842,276,744 - 2,306,035 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364842,276,463 - 2,306,119 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MASTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,856,072 - 48,880,475 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,855,895 - 48,877,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21054,162,099 - 54,186,773 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MASTL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1926,752,354 - 26,786,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl926,753,331 - 26,787,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605132,761,322 - 32,796,246 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013305   ⟹   ENSHGLP00000013167
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247962,216,034 - 2,243,962 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000013306   ⟹   ENSHGLP00000013168
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247962,216,034 - 2,243,962 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000013307   ⟹   ENSHGLP00000013169
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247962,216,034 - 2,242,897 (+)Ensembl
RefSeq Acc Id: XM_004859887   ⟹   XP_004859944
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,216,001 - 2,243,862 (+)NCBI
RefSeq Acc Id: XM_004859888   ⟹   XP_004859945
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,216,001 - 2,243,861 (+)NCBI
RefSeq Acc Id: XM_004859889   ⟹   XP_004859946
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,216,001 - 2,243,862 (+)NCBI
RefSeq Acc Id: XM_013077805   ⟹   XP_012933259
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,215,951 - 2,243,863 (+)NCBI
RefSeq Acc Id: XM_021240474   ⟹   XP_021096133
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,215,951 - 2,243,863 (+)NCBI
RefSeq Acc Id: XM_021240475   ⟹   XP_021096134
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,216,001 - 2,243,861 (+)NCBI
RefSeq Acc Id: XM_021240477   ⟹   XP_021096136
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,215,951 - 2,243,863 (+)NCBI
RefSeq Acc Id: XM_021240478   ⟹   XP_021096137
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,215,951 - 2,243,861 (+)NCBI
RefSeq Acc Id: XR_002387835
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247962,216,001 - 2,244,307 (+)NCBI
RefSeq Acc Id: XP_021096133   ⟸   XM_021240474
- Peptide Label: isoform X1
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096136   ⟸   XM_021240477
- Peptide Label: isoform X5
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012933259   ⟸   XM_013077805
- Peptide Label: isoform X7
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096137   ⟸   XM_021240478
- Peptide Label: isoform X6
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004859944   ⟸   XM_004859887
- Peptide Label: isoform X3
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004859946   ⟸   XM_004859889
- Peptide Label: isoform X8
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096134   ⟸   XM_021240475
- Peptide Label: isoform X2
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004859945   ⟸   XM_004859888
- Peptide Label: isoform X4
- UniProtKB: G5AUW5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000013169   ⟸   ENSHGLT00000013307
Ensembl Acc Id: ENSHGLP00000013168   ⟸   ENSHGLT00000013306
Ensembl Acc Id: ENSHGLP00000013167   ⟸   ENSHGLT00000013305


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009411 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013306 ENTREZGENE
  ENSHGLT00000013307 ENTREZGENE
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_kinase_AGC UniProtKB/TrEMBL
NCBI Gene Mastl ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE GREATWALL UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Protein kinase-like (PK-like) UniProtKB/TrEMBL
UniProt A0AAX6PUL8_HETGA UniProtKB/TrEMBL
  A0AAX6PUW7_HETGA UniProtKB/TrEMBL
  A0AAX6PVB8_HETGA UniProtKB/TrEMBL
  A0AAX6R1X3_HETGA UniProtKB/TrEMBL
  A0AAX6RH34_HETGA UniProtKB/TrEMBL
  A0AAX6RHQ1_HETGA UniProtKB/TrEMBL
  A0AAX6RJJ6_HETGA UniProtKB/TrEMBL
  A0AAX6RJY9_HETGA UniProtKB/TrEMBL
  G5AUW5 ENTREZGENE, UniProtKB/TrEMBL