Mastl (microtubule associated serine/threonine kinase like) - Rat Genome Database

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Gene: Mastl (microtubule associated serine/threonine kinase like) Chinchilla lanigera
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Symbol: Mastl
Name: microtubule associated serine/threonine kinase like
RGD ID: 8728660
Description: ENCODES a protein that exhibits kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN female meiosis II (ortholog); G2/M transition of mitotic cell cycle (ortholog); meiotic chromosome condensation (ortholog); ASSOCIATED WITH Scimitar Anomaly, Multiple Cardiac Malformations, and Craniofacial and Central Nervous System Abnormalities (ortholog); thrombocytopenia (ortholog); Thrombocytopenia 2 (ortholog); FOUND IN centrosome (ortholog); cleavage furrow (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: microtubule associated serine/threonine kinase-like; serine/threonine-protein kinase greatwall
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554292,591,203 - 2,617,784 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554292,591,173 - 2,617,084 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mastl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554292,591,203 - 2,617,784 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554292,591,173 - 2,617,084 (+)NCBIChiLan1.0ChiLan1.0
MASTL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381027,154,479 - 27,187,953 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1027,154,824 - 27,187,953 (+)EnsemblGRCh38hg38GRCh38
GRCh371027,444,281 - 27,476,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361027,484,298 - 27,515,854 (+)NCBINCBI36Build 36hg18NCBI36
Build 341027,484,297 - 27,515,854NCBI
Celera1027,160,210 - 27,192,290 (+)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1027,112,454 - 27,144,522 (+)NCBIHuRef
CHM1_11027,443,697 - 27,475,780 (+)NCBICHM1_1
T2T-CHM13v2.01027,184,483 - 27,217,949 (+)NCBIT2T-CHM13v2.0
Mastl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39223,006,549 - 23,046,036 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl223,005,618 - 23,046,036 (-)EnsemblGRCm39 Ensembl
GRCm38223,116,539 - 23,156,024 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl223,115,606 - 23,156,024 (-)EnsemblGRCm38mm10GRCm38
MGSCv37222,972,064 - 23,011,544 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36222,940,074 - 22,977,925 (-)NCBIMGSCv36mm8
Celera222,848,204 - 22,887,677 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map215.23NCBI
Mastl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81790,158,592 - 90,195,550 (-)NCBIGRCr8
mRatBN7.21785,250,512 - 85,287,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1785,251,997 - 85,287,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1788,736,222 - 88,771,568 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01792,571,598 - 92,606,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01786,588,377 - 86,623,723 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01789,839,562 - 89,875,855 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1789,742,140 - 89,876,825 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01791,504,296 - 91,540,607 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41796,722,615 - 96,757,971 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11796,733,772 - 96,751,272 (-)NCBI
Celera1783,608,795 - 83,644,003 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
MASTL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2839,783,630 - 39,816,414 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11039,788,957 - 39,821,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01027,264,475 - 27,296,085 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11027,626,892 - 27,658,180 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1027,626,892 - 27,658,180 (+)Ensemblpanpan1.1panPan2
MASTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.126,829,309 - 6,863,876 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl26,830,168 - 6,863,568 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha25,582,408 - 5,616,987 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.025,018,871 - 5,053,474 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl25,019,818 - 5,053,476 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.124,395,980 - 4,430,831 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.024,472,486 - 4,507,336 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.024,639,192 - 4,673,999 (+)NCBIUU_Cfam_GSD_1.0
Mastl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934426,109,771 - 26,141,730 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364842,276,744 - 2,306,035 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364842,276,463 - 2,306,119 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MASTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,856,072 - 48,880,475 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,855,895 - 48,877,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21054,162,099 - 54,186,773 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MASTL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1926,752,354 - 26,786,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl926,753,331 - 26,787,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605132,761,322 - 32,796,246 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mastl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247962,216,034 - 2,243,962 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247962,215,951 - 2,244,307 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000009617   ⟹   ENSCLAP00000009488
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554292,591,203 - 2,617,784 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000009618   ⟹   ENSCLAP00000009489
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554292,591,203 - 2,617,784 (+)Ensembl
RefSeq Acc Id: XM_005386869   ⟹   XP_005386926
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554292,591,173 - 2,617,084 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005386870   ⟹   XP_005386927
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554292,591,173 - 2,617,084 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515563   ⟹   XP_013371017
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554292,591,173 - 2,617,084 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386926 (Get FASTA)   NCBI Sequence Viewer  
  XP_005386927 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371017 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000009488
  ENSCLAP00000009488.1
  ENSCLAP00000009489
  ENSCLAP00000009489.1
RefSeq Acc Id: XP_005386926   ⟸   XM_005386869
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V2W0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005386927   ⟸   XM_005386870
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V7Z7 (UniProtKB/TrEMBL),   A0A8C2V2W0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371017   ⟸   XM_013515563
- Peptide Label: isoform X3
- UniProtKB: A0A8C2V2W0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000009488   ⟸   ENSCLAT00000009617
Ensembl Acc Id: ENSCLAP00000009489   ⟸   ENSCLAT00000009618

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006587 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009617 ENTREZGENE
  ENSCLAT00000009617.1 UniProtKB/TrEMBL
  ENSCLAT00000009618 ENTREZGENE
  ENSCLAT00000009618.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_kinase_AGC UniProtKB/TrEMBL
NCBI Gene Mastl ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE GREATWALL UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2V2W0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V7Z7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Mastl  microtubule associated serine/threonine kinase like    microtubule associated serine/threonine kinase-like  Symbol and/or name change 5135510 APPROVED