Piezo1 (piezo type mechanosensitive ion channel component 1 (Er blood group)) - Rat Genome Database

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Gene: Piezo1 (piezo type mechanosensitive ion channel component 1 (Er blood group)) Heterocephalus glaber
Analyze
Symbol: Piezo1
Name: piezo type mechanosensitive ion channel component 1 (Er blood group) (Ensembl:piezo type mechanosensitive ion channel component 1)
RGD ID: 18932973
Description: ENCODES a protein that exhibits identical protein binding (ortholog); mechanosensitive monoatomic cation channel activity (ortholog); monoatomic cation channel activity (ortholog); INVOLVED IN detection of mechanical stimulus (ortholog); monoatomic cation transmembrane transport (ortholog); monoatomic cation transport (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); adrenocorticotropic hormone deficiency (ortholog); autosomal recessive chronic granulomatous disease 4 (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: piezo type mechanosensitive ion channel component 1; piezo-type mechanosensitive ion channel component 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746821,726 - 871,481 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746821,651 - 871,481 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Piezo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746821,726 - 871,481 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746821,651 - 871,481 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PIEZO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,715,338 - 88,785,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,715,338 - 88,785,220 (-)EnsemblGRCh38hg38GRCh38
GRCh371688,781,746 - 88,851,628 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,309,247 - 87,351,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 341687,309,255 - 87,330,160NCBI
Celera1673,852,958 - 73,920,009 (-)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,477,633 - 74,549,500 (-)NCBIHuRef
CHM1_11690,193,016 - 90,262,540 (-)NCBICHM1_1
T2T-CHM13v2.01694,785,806 - 94,856,736 (-)NCBIT2T-CHM13v2.0
Piezo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,208,437 - 123,278,068 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,208,437 - 123,278,068 (-)EnsemblGRCm39 Ensembl
GRCm388122,481,698 - 122,551,329 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,481,698 - 122,551,329 (-)EnsemblGRCm38mm10GRCm38
MGSCv378125,005,598 - 125,075,229 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,372,380 - 125,437,419 (-)NCBIMGSCv36mm8
Celera8126,710,730 - 126,780,760 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.31NCBI
Piezo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,453,120 - 67,515,347 (-)NCBIGRCr8
mRatBN7.21950,544,580 - 50,606,812 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,544,582 - 50,606,501 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,339,473 - 57,401,301 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,019,509 - 58,081,421 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,238,096 - 60,299,923 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,305,494 - 55,367,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,305,496 - 55,367,353 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,014,939 - 66,075,869 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,770,967 - 52,834,347 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,776,154 - 52,852,837 (-)NCBI
Celera1949,784,059 - 49,845,831 (-)NCBICelera
Cytogenetic Map19q12NCBI
Piezo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,618,438 - 2,643,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,618,167 - 2,655,349 (-)NCBIChiLan1.0ChiLan1.0
PIEZO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,488,560 - 98,558,324 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,400,502 - 104,470,495 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,428,461 - 69,498,454 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,088,323 - 89,143,463 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,088,323 - 89,125,068 (-)Ensemblpanpan1.1panPan2
PIEZO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,584,153 - 64,640,423 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,570,035 - 64,640,375 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,595,638 - 64,651,743 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,804,439 - 64,860,493 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,804,155 - 64,860,483 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,830,683 - 64,886,668 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,662,209 - 64,718,234 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,068,355 - 65,124,410 (+)NCBIUU_Cfam_GSD_1.0
Piezo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,178,700 - 25,226,974 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641932,577 - 980,233 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641932,291 - 980,440 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIEZO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6914,709 - 967,111 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16914,480 - 967,113 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,610,402 - 54,612,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIEZO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,100,675 - 74,167,194 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,100,929 - 74,134,167 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,512,166 - 1,579,247 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021256576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01025582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000018744   ⟹   ENSHGLP00000018560
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624746821,726 - 871,481 (+)Ensembl
RefSeq Acc Id: XM_021256576   ⟹   XP_021112235
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624746821,651 - 871,481 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021112235 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018560
Reference Protein Sequences
RefSeq Acc Id: XP_021112235   ⟸   XM_021256576
- UniProtKB: G5C2U0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000018560   ⟸   ENSHGLT00000018744


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013281 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000018744 ENTREZGENE
InterPro Piezo UniProtKB/TrEMBL
  Piezo_dom UniProtKB/TrEMBL
  Piezo_RRas-bd_dom UniProtKB/TrEMBL
NCBI Gene Piezo1 ENTREZGENE
PANTHER PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT UniProtKB/TrEMBL
  PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL HOMOLOG UniProtKB/TrEMBL
Pfam PIEZO UniProtKB/TrEMBL
  Piezo_RRas_bdg UniProtKB/TrEMBL
UniProt G5C2U0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-11-07 Piezo1  piezo type mechanosensitive ion channel component 1 (Er blood group)  Piezo1  piezo type mechanosensitive ion channel component 1  Symbol and/or name change 5135510 APPROVED