Ptprq (protein tyrosine phosphatase receptor type Q) - Rat Genome Database

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Gene: Ptprq (protein tyrosine phosphatase receptor type Q) Heterocephalus glaber
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Symbol: Ptprq
Name: protein tyrosine phosphatase receptor type Q
RGD ID: 18932396
Description: ENCODES a protein that exhibits histone H2AXY142 phosphatase activity (inferred); non-membrane spanning protein tyrosine phosphatase activity (inferred); phosphoprotein phosphatase activity (inferred); INVOLVED IN detection of mechanical stimulus involved in sensory perception of sound (ortholog); hematopoietic progenitor cell differentiation (ortholog); inner ear morphogenesis (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; ASSOCIATED WITH autosomal dominant centronuclear myopathy (ortholog); autosomal dominant nonsyndromic deafness 73 (ortholog); autosomal recessive nonsyndromic deafness (ortholog); FOUND IN apical plasma membrane (ortholog); stereocilium base (ortholog); stereocilium bundle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol phosphatase PTPRQ
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475017,622,627 - 17,863,899 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475017,621,520 - 17,863,902 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ptprq
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475017,622,627 - 17,863,899 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475017,621,520 - 17,863,902 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTPRQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381280,444,235 - 80,680,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1280,402,178 - 80,680,273 (+)EnsemblGRCh38hg38GRCh38
GRCh371280,838,015 - 81,074,052 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361279,363,383 - 79,531,770 (+)NCBINCBI36Build 36hg18NCBI36
Celera1280,503,778 - 80,740,182 (+)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1277,895,115 - 78,130,849 (+)NCBIHuRef
CHM1_11280,804,585 - 81,040,375 (+)NCBICHM1_1
T2T-CHM13v2.01280,422,862 - 80,658,975 (+)NCBIT2T-CHM13v2.0
Ptprq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910107,350,224 - 107,555,939 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10107,352,910 - 107,555,912 (-)EnsemblGRCm39 Ensembl
GRCm3810107,514,363 - 107,720,098 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10107,517,049 - 107,720,051 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710106,954,416 - 107,157,083 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610106,921,470 - 107,124,137 (-)NCBIMGSCv36mm8
Celera10109,459,813 - 109,656,738 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.97NCBI
Ptprq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8744,720,916 - 44,903,291 (-)NCBIGRCr8
mRatBN7.2742,834,455 - 43,016,807 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl742,837,109 - 43,016,917 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx744,746,942 - 44,929,416 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0746,950,023 - 47,132,521 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0746,727,852 - 46,910,339 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0749,763,657 - 50,034,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl749,763,657 - 50,034,932 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0749,939,446 - 50,045,544 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0749,773,565 - 49,852,881 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4746,224,075 - 46,400,107 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1746,244,345 - 46,420,378 (-)NCBI
Celera739,709,561 - 39,889,789 (-)NCBICelera
RH 3.4 Map7352.32RGD
Cytogenetic Map7q21NCBI
Ptprq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540519,123,905 - 19,318,619 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540519,123,905 - 19,318,619 (+)NCBIChiLan1.0ChiLan1.0
PTPRQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21088,485,852 - 88,728,258 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11288,482,247 - 88,724,653 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01277,957,758 - 78,200,206 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11281,070,130 - 81,310,857 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1281,068,545 - 81,310,857 (+)Ensemblpanpan1.1panPan2
PTPRQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11522,771,653 - 23,017,694 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1522,825,348 - 23,013,762 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1523,195,305 - 23,441,460 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01523,131,808 - 23,378,520 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1523,132,778 - 23,375,811 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11522,709,249 - 22,955,886 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01522,768,982 - 23,015,356 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01523,008,878 - 23,255,710 (+)NCBIUU_Cfam_GSD_1.0
Ptprq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494537,341,524 - 37,539,896 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366981,372,607 - 1,569,905 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366981,372,604 - 1,569,905 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5100,787,027 - 101,033,334 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15100,787,025 - 101,081,145 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25105,794,917 - 105,833,241 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11175,943,793 - 76,154,604 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1175,943,260 - 76,154,083 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037169,282,954 - 169,531,980 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000016590   ⟹   ENSHGLP00000016421
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475017,622,627 - 17,863,899 (-)Ensembl
RefSeq Acc Id: XM_021258496   ⟹   XP_021114155
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475017,621,520 - 17,863,902 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021114155 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016421
RefSeq Acc Id: XP_021114155   ⟸   XM_021258496
- UniProtKB: G5C9J4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000016421   ⟸   ENSHGLT00000016590


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011762 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000016590 ENTREZGENE
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
  Protein tyrosine phosphatase superfamily UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  RTP_Phos/Ushers UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptprq ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  PHOSPHATIDYLINOSITOL PHOSPHATASE PTPRQ UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP (Phosphotyrosine protein) phosphatases II UniProtKB/TrEMBL
  Fibronectin type III UniProtKB/TrEMBL
UniProt A0AAX6T068_HETGA UniProtKB/TrEMBL
  G5C9J4 ENTREZGENE, UniProtKB/TrEMBL