Mid1 (midline 1) - Rat Genome Database

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Gene: Mid1 (midline 1) Heterocephalus glaber
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Symbol: Mid1
Name: midline 1
RGD ID: 18931765
Description: ENCODES a protein that exhibits enzyme binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of microtubule depolymerization (ortholog); ASSOCIATED WITH autistic disorder (ortholog); B-Cell Immunodeficiency, Distal Limb Anomalies, and Urogenital Malformations (ortholog); Dandy-Walker syndrome (ortholog); FOUND IN centriolar satellite (inferred); cytoplasm (inferred); cytoplasmic microtubule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase Midline-1; midline 1 (Opitz/BBB syndrome); Midline-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248823,627,879 - 3,876,526 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248823,504,660 - 3,876,526 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Mid1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248823,627,879 - 3,876,526 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248823,504,660 - 3,876,526 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MID1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X10,445,310 - 10,833,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX10,445,310 - 10,833,654 (-)EnsemblGRCh38hg38GRCh38
GRCh37X10,413,350 - 10,851,802 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X10,373,596 - 10,761,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X10,225,901 - 10,398,195NCBI
CeleraX14,584,610 - 14,973,762 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX8,245,662 - 8,632,012 (-)NCBIHuRef
CHM1_1X10,443,740 - 10,882,213 (-)NCBICHM1_1
T2T-CHM13v2.0X10,027,869 - 10,416,213 (-)NCBIT2T-CHM13v2.0
Mid1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X168,468,178 - 168,773,692 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX168,468,195 - 168,773,794 (+)EnsemblGRCm39 Ensembl
GRCm38X169,685,199 - 169,990,798 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX169,685,199 - 170,005,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X166,123,179 - 166,428,730 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X165,029,352 - 165,344,845 (+)NCBIMGSCv36mm8
CeleraX152,849,611 - 153,131,383 (+)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX79.19NCBI
Mid1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X27,678,248 - 28,053,049 (-)NCBIGRCr8
mRatBN7.2X24,116,674 - 24,491,205 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX24,120,293 - 24,248,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX25,102,036 - 25,230,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X28,523,075 - 28,651,528 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X24,768,159 - 24,896,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X25,458,782 - 25,839,941 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX25,458,771 - 25,628,272 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X25,869,975 - 26,249,296 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X44,751,950 - 44,879,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X44,805,418 - 44,933,468 (-)NCBI
CeleraX24,547,301 - 24,674,105 (-)NCBICelera
Cytogenetic MapXq13NCBI
Mid1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555442,484,854 - 2,719,112 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555442,379,766 - 2,718,282 (+)NCBIChiLan1.0ChiLan1.0
MID1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X12,247,798 - 12,635,811 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X12,251,464 - 12,483,362 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X3,075,834 - 3,463,845 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X10,328,476 - 10,715,914 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX10,328,476 - 10,459,284 (-)Ensemblpanpan1.1panPan2
MID1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X7,087,890 - 7,438,553 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX7,089,831 - 7,194,267 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX7,042,862 - 7,395,336 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X7,033,632 - 7,390,212 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX7,036,207 - 7,242,435 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X7,023,168 - 7,375,574 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X7,058,915 - 7,411,617 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X7,049,392 - 7,406,171 (-)NCBIUU_Cfam_GSD_1.0
Mid1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X414,418 - 767,610 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936470414,409 - 576,669 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936470414,420 - 576,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MID1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX7,237,942 - 7,620,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X7,235,386 - 7,906,049 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X7,630,961 - 7,771,708 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MID1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X8,897,424 - 9,289,187 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX8,895,602 - 9,076,871 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605610,595,252 - 10,977,148 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000001924   ⟹   ENSHGLP00000001878
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248823,627,879 - 3,872,617 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000001925   ⟹   ENSHGLP00000001879
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248823,711,401 - 3,876,526 (+)Ensembl
RefSeq Acc Id: XM_004871029   ⟹   XP_004871086
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248823,711,390 - 3,876,526 (+)NCBI
RefSeq Acc Id: XM_013067892   ⟹   XP_012923346
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248823,750,784 - 3,876,526 (+)NCBI
RefSeq Acc Id: XM_013067893   ⟹   XP_012923347
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248823,504,660 - 3,876,526 (+)NCBI
RefSeq Acc Id: XM_013067894   ⟹   XP_012923348
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248823,711,390 - 3,876,526 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004871086 (Get FASTA)   NCBI Sequence Viewer  
  XP_012923346 (Get FASTA)   NCBI Sequence Viewer  
  XP_012923347 (Get FASTA)   NCBI Sequence Viewer  
  XP_012923348 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04766 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001879
  ENSHGLP00100007389
RefSeq Acc Id: XP_012923347   ⟸   XM_013067893
- Peptide Label: isoform X1
- UniProtKB: G5B655 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004871086   ⟸   XM_004871029
- Peptide Label: isoform X1
- UniProtKB: G5B655 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923348   ⟸   XM_013067894
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012923346   ⟸   XM_013067892
- Peptide Label: isoform X1
- UniProtKB: G5B655 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000001878   ⟸   ENSHGLT00000001924
Ensembl Acc Id: ENSHGLP00000001879   ⟸   ENSHGLT00000001925


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001434 Ensembl, ENTREZGENE
  ENSHGLG00100005528 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001925 ENTREZGENE
  ENSHGLT00100007485 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  4.10.830.40 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Bbox_C UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  COS_domain UniProtKB/TrEMBL
  E3_ligase_FN3/SPRY UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  MID1 UniProtKB/TrEMBL
  MID1_Bbox1_Zfn UniProtKB/TrEMBL
  Midline-1_COS UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report hgl:101701977 UniProtKB/TrEMBL
NCBI Gene Mid1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED UniProtKB/TrEMBL
  PTHR24099:SF23 UniProtKB/TrEMBL
Pfam ANCHR-like_BBOX UniProtKB/TrEMBL
  COS UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  COS UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBC UniProtKB/TrEMBL
  BBOX UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0AAX6QQV9_HETGA UniProtKB/TrEMBL
  G5B655 ENTREZGENE, UniProtKB/TrEMBL