Sncb (synuclein beta) - Rat Genome Database

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Gene: Sncb (synuclein beta) Heterocephalus glaber
Analyze
Symbol: Sncb
Name: synuclein beta
RGD ID: 18929597
Description: ENCODES a protein that exhibits alpha-tubulin binding (ortholog); beta-tubulin binding (ortholog); calcium ion binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); dopamine metabolic process (ortholog); negative regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute megakaryocytic leukemia (ortholog); Alzheimer's disease (ortholog); Autosomal Dominant Diffuse Lewy Body Disease (ortholog); FOUND IN axon terminus (ortholog); growth cone (ortholog); inclusion body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-synuclein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473313,506,180 - 13,513,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473313,506,181 - 13,513,979 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sncb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473313,506,180 - 13,513,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473313,506,181 - 13,513,979 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SNCB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385176,620,082 - 176,630,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5176,620,082 - 176,630,556 (-)EnsemblGRCh38hg38GRCh38
GRCh375176,047,083 - 176,057,535 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365175,979,816 - 175,990,163 (-)NCBINCBI36Build 36hg18NCBI36
Build 345175,979,816 - 175,990,163NCBI
Celera5172,442,697 - 172,464,864 (+)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5170,970,990 - 170,981,256 (-)NCBIHuRef
CHM1_15175,479,633 - 175,489,981 (-)NCBICHM1_1
T2T-CHM13v2.05177,166,665 - 177,177,114 (-)NCBIT2T-CHM13v2.0
Sncb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391354,906,673 - 54,914,435 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1354,906,673 - 54,914,408 (-)EnsemblGRCm39 Ensembl
GRCm381354,758,860 - 54,766,622 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,758,860 - 54,766,595 (-)EnsemblGRCm38mm10GRCm38
MGSCv371354,860,221 - 54,867,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361354,768,482 - 54,776,062 (-)NCBIMGSCv36mm8
Celera1355,824,326 - 55,831,944 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1329.28NCBI
Sncb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8179,851,825 - 9,860,143 (+)NCBIGRCr8
mRatBN7.2179,846,802 - 9,855,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,846,802 - 9,855,012 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx179,860,708 - 9,869,180 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,394,284 - 11,402,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0179,857,117 - 9,865,594 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,384,472 - 10,392,776 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,384,511 - 10,392,843 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,510,521 - 12,518,728 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,907,498 - 15,915,705 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11715,907,640 - 15,915,194 (+)NCBI
Celera179,921,982 - 9,930,166 (+)NCBICelera
Cytogenetic Map17p14NCBI
Sncb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,894,204 - 28,903,095 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,894,204 - 28,903,095 (-)NCBIChiLan1.0ChiLan1.0
SNCB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24171,700,736 - 171,711,148 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15169,840,275 - 169,850,687 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05171,918,297 - 171,928,672 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15178,988,314 - 178,998,805 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5178,988,439 - 178,998,800 (-)Ensemblpanpan1.1panPan2
SNCB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,710,236 - 36,719,455 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl436,616,039 - 36,764,501 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha436,677,103 - 36,686,289 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0437,076,409 - 37,085,600 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl437,048,276 - 37,103,097 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1436,902,261 - 36,911,447 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0437,089,947 - 37,099,120 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0437,598,214 - 37,607,385 (+)NCBIUU_Cfam_GSD_1.0
Sncb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213121,853,363 - 121,863,441 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936597878,286 - 888,331 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936597878,270 - 888,346 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNCB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,287,759 - 81,302,861 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1281,287,764 - 81,302,859 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2282,889,540 - 82,899,597 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNCB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12378,626,876 - 78,637,337 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,627,479 - 78,636,287 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660759,760,600 - 9,770,954 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014270   ⟹   ENSHGLP00000014127
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473313,506,180 - 13,513,712 (+)Ensembl
RefSeq Acc Id: XM_004836323   ⟹   XP_004836380
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473313,506,181 - 13,513,979 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004836380 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014127
GenBank Protein JAO03433 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004836380   ⟸   XM_004836323
- UniProtKB: A0A0P6JG91 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014127   ⟸   ENSHGLT00000014270


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010088 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014270 ENTREZGENE
Gene3D-CATH Helix hairpin bin UniProtKB/TrEMBL
InterPro Synuclein UniProtKB/TrEMBL
  Synuclein_beta UniProtKB/TrEMBL
KEGG Report hgl:101708817 UniProtKB/TrEMBL
NCBI Gene Sncb ENTREZGENE
PANTHER PTHR13820 UniProtKB/TrEMBL
  PTHR13820:SF4 UniProtKB/TrEMBL
Pfam Synuclein UniProtKB/TrEMBL
PRINTS BSYNUCLEIN UniProtKB/TrEMBL
  SYNUCLEIN UniProtKB/TrEMBL
Superfamily-SCOP Synuclein UniProtKB/TrEMBL
UniProt A0A0P6JG91 ENTREZGENE, UniProtKB/TrEMBL