Plxnc1 (plexin C1) - Rat Genome Database

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Gene: Plxnc1 (plexin C1) Heterocephalus glaber
Analyze
Symbol: Plxnc1
Name: plexin C1
RGD ID: 18927562
Description: ENCODES a protein that exhibits semaphorin receptor activity (inferred); INVOLVED IN regulation of synapse pruning (ortholog); ASSOCIATED WITH endometriosis (ortholog); genetic disease (ortholog); nephronophthisis 18 (ortholog); FOUND IN cerebellar climbing fiber to Purkinje cell synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plexin-C1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475012,641,674 - 12,777,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475012,639,292 - 12,777,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Plxnc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475012,641,674 - 12,777,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475012,639,292 - 12,777,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLXNC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381294,148,577 - 94,307,675 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1294,148,577 - 94,307,675 (+)EnsemblGRCh38hg38GRCh38
GRCh371294,542,353 - 94,701,451 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361293,066,630 - 93,223,356 (+)NCBINCBI36Build 36hg18NCBI36
Build 341293,044,966 - 93,201,693NCBI
Celera1294,213,729 - 94,370,485 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1291,610,270 - 91,768,612 (+)NCBIHuRef
CHM1_11294,507,552 - 94,666,454 (+)NCBICHM1_1
T2T-CHM13v2.01294,129,732 - 94,288,500 (+)NCBIT2T-CHM13v2.0
Plxnc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391094,626,728 - 94,780,875 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1094,626,728 - 94,780,697 (-)EnsemblGRCm39 Ensembl
GRCm381094,790,866 - 94,945,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1094,790,866 - 94,944,835 (-)EnsemblGRCm38mm10GRCm38
MGSCv371094,253,611 - 94,407,212 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,222,985 - 94,374,266 (-)NCBIMGSCv36mm8
Celera1096,763,537 - 96,917,770 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.09NCBI
Plxnc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8731,276,978 - 31,430,823 (-)NCBIGRCr8
mRatBN7.2729,390,038 - 29,543,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl729,390,048 - 29,543,779 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0735,848,083 - 36,000,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl735,850,398 - 36,000,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0735,912,101 - 36,063,768 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4731,984,866 - 32,137,758 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,007,444 - 32,157,845 (-)NCBI
Celera726,469,439 - 26,621,620 (-)NCBICelera
Cytogenetic Map7q13NCBI
Plxnc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540530,885,278 - 31,021,544 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540530,885,277 - 31,023,947 (+)NCBIChiLan1.0ChiLan1.0
PLXNC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210102,194,435 - 102,352,972 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112102,190,829 - 102,349,366 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01291,694,449 - 91,852,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11295,092,467 - 95,251,251 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1295,093,332 - 95,251,249 (+)Ensemblpanpan1.1panPan2
PLXNC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11534,279,880 - 34,417,134 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1534,279,932 - 34,417,720 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,730,384 - 34,867,603 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,943,288 - 35,080,504 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,942,721 - 35,079,123 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11534,216,942 - 34,354,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01534,306,467 - 34,443,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01534,575,260 - 34,712,431 (+)NCBIUU_Cfam_GSD_1.0
Plxnc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494525,564,925 - 25,709,461 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650710,525,975 - 10,670,514 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650710,525,975 - 10,670,511 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLXNC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl588,900,234 - 89,055,924 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1588,900,238 - 89,055,837 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,325,725 - 93,459,846 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLXNC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11189,549,312 - 89,701,890 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037155,455,641 - 155,614,944 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004844955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01030590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000008080   ⟹   ENSHGLP00000007992
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475012,641,674 - 12,777,702 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000008081   ⟹   ENSHGLP00000007993
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475012,641,674 - 12,777,702 (-)Ensembl
RefSeq Acc Id: XM_004844955   ⟹   XP_004845012
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475012,639,292 - 12,777,237 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004845012 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007993
Reference Protein Sequences
RefSeq Acc Id: XP_004845012   ⟸   XM_004844955
- UniProtKB: G5C0U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000007993   ⟸   ENSHGLT00000008081
RefSeq Acc Id: ENSHGLP00000007992   ⟸   ENSHGLT00000008080


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005788 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000008081 ENTREZGENE
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
  YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  Plexin UniProtKB/TrEMBL
  Plexin_cytoplasmic_RasGAP_dom UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Plxnc1 ENTREZGENE
PANTHER PLEXIN UniProtKB/TrEMBL
  PLEXIN-C1 UniProtKB/TrEMBL
Pfam Plexin_cytopl UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  TIG UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
Superfamily-SCOP GTPase activation domain, GAP UniProtKB/TrEMBL
  Plexin repeat UniProtKB/TrEMBL
  Sema domain UniProtKB/TrEMBL
UniProt G5C0U3 ENTREZGENE, UniProtKB/TrEMBL