Plxnc1 (plexin C1) - Rat Genome Database

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Gene: Plxnc1 (plexin C1) Ictidomys tridecemlineatus
Analyze
Symbol: Plxnc1
Name: plexin C1
RGD ID: 12560688
Description: ENCODES a protein that exhibits semaphorin receptor activity (inferred); INVOLVED IN negative regulation of cell adhesion (inferred); positive regulation of axonogenesis (inferred); regulation of cell migration (inferred); ASSOCIATED WITH endometriosis (ortholog); genetic disease (ortholog); nephronophthisis 18 (ortholog); FOUND IN cerebellar climbing fiber to Purkinje cell synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plexin-C1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494525,564,925 - 25,709,461 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650710,525,975 - 10,670,514 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650710,525,975 - 10,670,511 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Plxnc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494525,564,925 - 25,709,461 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650710,525,975 - 10,670,514 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650710,525,975 - 10,670,511 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLXNC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381294,148,577 - 94,307,675 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1294,148,577 - 94,307,675 (+)EnsemblGRCh38hg38GRCh38
GRCh371294,542,353 - 94,701,451 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361293,066,630 - 93,223,356 (+)NCBINCBI36Build 36hg18NCBI36
Build 341293,044,966 - 93,201,693NCBI
Celera1294,213,729 - 94,370,485 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1291,610,270 - 91,768,612 (+)NCBIHuRef
CHM1_11294,507,552 - 94,666,454 (+)NCBICHM1_1
T2T-CHM13v2.01294,129,732 - 94,288,500 (+)NCBIT2T-CHM13v2.0
Plxnc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391094,626,728 - 94,780,875 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1094,626,728 - 94,780,697 (-)EnsemblGRCm39 Ensembl
GRCm381094,790,866 - 94,945,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1094,790,866 - 94,944,835 (-)EnsemblGRCm38mm10GRCm38
MGSCv371094,253,611 - 94,407,212 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,222,985 - 94,374,266 (-)NCBIMGSCv36mm8
Celera1096,763,537 - 96,917,770 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.09NCBI
Plxnc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8731,276,978 - 31,430,823 (-)NCBIGRCr8
mRatBN7.2729,390,038 - 29,543,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl729,390,048 - 29,543,779 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0735,848,083 - 36,000,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl735,850,398 - 36,000,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0735,912,101 - 36,063,768 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4731,984,866 - 32,137,758 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,007,444 - 32,157,845 (-)NCBI
Celera726,469,439 - 26,621,620 (-)NCBICelera
Cytogenetic Map7q13NCBI
Plxnc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540530,885,278 - 31,021,544 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540530,885,277 - 31,023,947 (+)NCBIChiLan1.0ChiLan1.0
PLXNC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210102,194,435 - 102,352,972 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112102,190,829 - 102,349,366 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01291,694,449 - 91,852,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11295,092,467 - 95,251,251 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1295,093,332 - 95,251,249 (+)Ensemblpanpan1.1panPan2
PLXNC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11534,279,880 - 34,417,134 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1534,279,932 - 34,417,720 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,730,384 - 34,867,603 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,943,288 - 35,080,504 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,942,721 - 35,079,123 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11534,216,942 - 34,354,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01534,306,467 - 34,443,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01534,575,260 - 34,712,431 (+)NCBIUU_Cfam_GSD_1.0
PLXNC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl588,900,234 - 89,055,924 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1588,900,238 - 89,055,837 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2593,325,725 - 93,459,846 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLXNC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11189,549,312 - 89,701,890 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037155,455,641 - 155,614,944 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plxnc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475012,641,674 - 12,777,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475012,639,292 - 12,777,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005324463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000000730   ⟹   ENSSTOP00000000654
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493650710,525,975 - 10,670,514 (+)Ensembl
RefSeq Acc Id: XM_005324463   ⟹   XP_005324520
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494525,564,925 - 25,709,461 (-)NCBI
SpeTri2.0NW_00493650710,525,975 - 10,670,511 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005324520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000000654.3
Reference Protein Sequences
RefSeq Acc Id: XP_005324520   ⟸   XM_005324463
- UniProtKB: I3LX88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000000654   ⟸   ENSSTOT00000000730
Protein Domains
Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000728 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000730.3 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  Plexin UniProtKB/TrEMBL
  Plexin-C1_Sema UniProtKB/TrEMBL
  Plexin_cytoplasmic_RasGAP_dom UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Plxnc1 ENTREZGENE
PANTHER PLEXIN-C1 UniProtKB/TrEMBL
  PTHR22625 UniProtKB/TrEMBL
Pfam Plexin_cytopl UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  TIG UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
UniProt I3LX88 ENTREZGENE, UniProtKB/TrEMBL