Oaz3 (ornithine decarboxylase antizyme 3) - Rat Genome Database

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Gene: Oaz3 (ornithine decarboxylase antizyme 3) Heterocephalus glaber
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Symbol: Oaz3
Name: ornithine decarboxylase antizyme 3
RGD ID: 18927072
Description: ENCODES a protein that exhibits ankyrin repeat binding (ortholog); INVOLVED IN negative regulation of polyamine transmembrane transport (ortholog); negative regulation of stress fiber assembly (ortholog); positive regulation of intracellular protein transport (ortholog); PARTICIPATES IN polyamine metabolic pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); immunodeficiency 42 (ortholog); MHC class II deficiency (ortholog); FOUND IN nucleoplasm (ortholog); sperm flagellum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477219,442,015 - 19,445,182 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477219,438,742 - 19,445,293 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Oaz3Naked Mole-Ratgastrointestinal stromal tumor  ISOOAZ3 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Oaz3Naked Mole-Ratimmunodeficiency 42  ISOOAZ3 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiencyClinVarPMID:28492532
Oaz3Naked Mole-RatMHC class II deficiency  ISOOAZ3 (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
Oaz3Naked Mole-Ratparathyroid carcinoma  ISOOAZ3 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Oaz3Naked Mole-Ratsevere congenital neutropenia 3  ISOOAZ3 (Homo sapiens)8554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:28492532
Oaz3Naked Mole-Ratsevere congenital neutropenia 5  ISOOAZ3 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532


Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Oaz3Naked Mole-Ratcytoplasm located_inIEAPANTHER:PTN000031468150520179 TreeGrafterGO_REF:0000118
Oaz3Naked Mole-Ratnucleoplasm located_inISOOAZ3 (Homo sapiens)9068941 HPAGO_REF:0000052
Oaz3Naked Mole-Ratnucleus located_inIEAPANTHER:PTN000031468150520179 TreeGrafterGO_REF:0000118
Oaz3Naked Mole-Ratsperm flagellum  ISOOaz3 (Rattus norvegicus)9068941 RGDPMID:21712390 and REF_RGD_ID:7245493

Molecular Function
1 to 11 of 11 rows

  
1 to 11 of 11 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Oaz3Naked Mole-Ratpolyamine metabolic pathway   ISOOAZ3 (Homo sapiens)9068941 RGDPMID:21849468 and REF_RGD_ID:7244195
PMID:22301074   PMID:30032202  



Oaz3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477219,442,015 - 19,445,182 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477219,438,742 - 19,445,293 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
OAZ3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,762,969 - 151,771,330 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,762,899 - 151,771,334 (+)EnsemblGRCh38hg38GRCh38
GRCh371151,735,445 - 151,743,806 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,005,755 - 150,010,429 (+)NCBINCBI36Build 36hg18NCBI36
Build 341148,552,203 - 148,556,878NCBI
Celera1124,850,058 - 124,858,481 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1123,112,255 - 123,120,706 (+)NCBIHuRef
CHM1_11153,130,577 - 153,138,934 (+)NCBICHM1_1
T2T-CHM13v2.01150,886,358 - 150,894,807 (+)NCBIT2T-CHM13v2.0
Oaz3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,340,694 - 94,343,958 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,339,721 - 94,351,222 (-)EnsemblGRCm39 Ensembl
GRCm38394,433,387 - 94,436,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,432,414 - 94,443,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv37394,237,088 - 94,240,538 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36394,518,794 - 94,522,020 (-)NCBIMGSCv36mm8
Celera395,877,993 - 95,881,443 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.66NCBI
Oaz3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82184,762,242 - 184,765,176 (-)NCBIGRCr8
mRatBN7.22182,073,212 - 182,076,147 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,073,215 - 182,082,399 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2189,736,364 - 189,739,297 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02187,540,629 - 187,543,554 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,368,832 - 182,371,765 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02195,675,925 - 195,678,859 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2195,676,048 - 195,678,848 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,154,619 - 215,157,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,408,566 - 189,411,500 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2174,623,440 - 174,626,374 (-)NCBICelera
Cytogenetic Map2q34NCBI
Oaz3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955589654,088 - 658,003 (-)NCBIChiLan1.0ChiLan1.0
OAZ3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,052,408 - 98,060,973 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,803,599 - 97,812,162 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,121,375 - 127,129,940 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11130,765,003 - 130,773,974 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,765,290 - 130,773,859 (+)Ensemblpanpan1.1panPan2
OAZ3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,789,541 - 60,792,954 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,786,963 - 60,792,954 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1760,230,905 - 60,234,318 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,806,097 - 61,809,510 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,803,498 - 61,809,510 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11760,632,865 - 60,636,278 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,719,198 - 60,722,609 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01761,448,108 - 61,451,521 (+)NCBIUU_Cfam_GSD_1.0
Oaz3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,932,990 - 22,935,704 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,963,415 - 1,965,950 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,963,372 - 1,966,086 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OAZ3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,439,993 - 97,448,493 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,439,993 - 97,448,493 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24106,463,000 - 106,471,500 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OAZ3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12011,916,163 - 11,922,770 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603811,486,262 - 11,492,728 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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RefSeq Transcripts XM_004854097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01051521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000006947   ⟹   ENSHGLP00000006863
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477219,442,015 - 19,445,182 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000006948   ⟹   ENSHGLP00000006864
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477219,442,015 - 19,445,182 (+)Ensembl
RefSeq Acc Id: XM_004854097   ⟹   XP_004854154
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477219,438,742 - 19,445,293 (+)NCBI
Protein RefSeqs XP_004854154 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004854154   ⟸   XM_004854097
- UniProtKB: A0AAX6PL71 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006863   ⟸   ENSHGLT00000006947
Ensembl Acc Id: ENSHGLP00000006864   ⟸   ENSHGLT00000006948



1 to 11 of 11 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000005010 Ensembl
Gene3D-CATH 3.40.630.60 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  ODC_AZ UniProtKB/TrEMBL
  ODC_AZ_sf UniProtKB/TrEMBL
NCBI Gene Oaz3 ENTREZGENE
PANTHER ORNITHINE DECARBOXYLASE ANTIZYME UniProtKB/TrEMBL
  ORNITHINE DECARBOXYLASE ANTIZYME 3 UniProtKB/TrEMBL
Pfam ODC_AZ UniProtKB/TrEMBL
Superfamily-SCOP Acyl-CoA N-acyltransferases (Nat) UniProtKB/TrEMBL
UniProt A0AAX6PL71 ENTREZGENE, UniProtKB/TrEMBL
1 to 11 of 11 rows